Page last updated: 2024-11-03

propofol and Anaphylaxis

propofol has been researched along with Anaphylaxis in 48 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Anaphylaxis: An acute hypersensitivity reaction due to exposure to a previously encountered ANTIGEN. The reaction may include rapidly progressing URTICARIA, respiratory distress, vascular collapse, systemic SHOCK, and death.

Research Excerpts

ExcerptRelevanceReference
" Propofol induced anaphylaxis has been described."7.83Severe anaphylaxis to Propofol: first case of evidence of sensitization to soy oil. ( Beaudouin, E; Jacquenet, S; Kohler, C; Moneret-Vautrin, DA; Nguyen-Grosjean, VM; Richard, C, 2016)
"To report a case of anaphylaxis due to propofol in a child with allergies to egg and peanut oil."7.72Possible anaphylaxis after propofol in a child with food allergy. ( Buck, ML; Hendrick, AE; Hofer, KN; McCarthy, MW, 2003)
"Anaphylaxis to propofol is rare and has not been previously reported in Asia."7.71Anaphylaxis after propofol infusion for Port-A-Cath insertion in a 35-year old man. ( Hong, RL; Kuo, PH; Tsai, MH; Yang, PC, 2001)
"Propofol is an anesthetic agent suspended in an emulsion system that includes egg yolk lecithin and soybean oil, because of which, there is concern about the use of propofol in patients allergic to these substances."5.46Incidence of anaphylactic reactions after propofol administration in dogs. ( Ishida, T; Murakami, A; Ono, S; Onuma, M; Sano, T; Terada, M, 2017)
"Suspecting the development of pulmonary embolism or anaphylaxis, we performed transesophageal echography; however, no evidence of right heart dilatation was observed, indicating a low possibility of pulmonary embolism."5.43[A Case of Rocuronium-induced Anaphylaxis in Which Surgery was Subsequently Performed under General Anesthesia without Neuromuscular Blocking Agents]. ( Horiuchi, T; Saito, S; Takazawa, T, 2016)
" The aim of this report is to describe a suspected anaphylactic reaction to propofol in a 14 years old Shih-Tzu undergoing general anaesthesia for ovariohysterectomy due to a pyometra."4.02A Suspected Anaphylactoid Reaction to Propofol in a Dog. ( Del Prete, T; Scarabelli, S, 2021)
" Propofol induced anaphylaxis has been described."3.83Severe anaphylaxis to Propofol: first case of evidence of sensitization to soy oil. ( Beaudouin, E; Jacquenet, S; Kohler, C; Moneret-Vautrin, DA; Nguyen-Grosjean, VM; Richard, C, 2016)
"To report a case of anaphylaxis due to propofol in a child with allergies to egg and peanut oil."3.72Possible anaphylaxis after propofol in a child with food allergy. ( Buck, ML; Hendrick, AE; Hofer, KN; McCarthy, MW, 2003)
"Anaphylaxis to propofol is rare and has not been previously reported in Asia."3.71Anaphylaxis after propofol infusion for Port-A-Cath insertion in a 35-year old man. ( Hong, RL; Kuo, PH; Tsai, MH; Yang, PC, 2001)
"Fourteen patients who had had a life-threatening reaction within a few minutes after receiving propofol (Diprivan) were investigated for anaphylaxis 4-6 weeks after the incident."3.68Life-threatening anaphylactoid reactions to propofol (Diprivan) ( Gueant, JL; Laxenaire, MC; Mata-Bermejo, E; Moneret-Vautrin, DA, 1992)
"Recently, the pathophysiology of anaphylactic reactions via mast cell related G-protein und complement-activated pseudo-allergy have been added to the "old" IgE mediated etiology."1.72[Peri-Operative Anaphylaxis - Antiquated Customs and News Towards the Culprits]. ( Bayerl, C, 2022)
"Propofol is an anesthetic agent suspended in an emulsion system that includes egg yolk lecithin and soybean oil, because of which, there is concern about the use of propofol in patients allergic to these substances."1.46Incidence of anaphylactic reactions after propofol administration in dogs. ( Ishida, T; Murakami, A; Ono, S; Onuma, M; Sano, T; Terada, M, 2017)
"Suspecting the development of pulmonary embolism or anaphylaxis, we performed transesophageal echography; however, no evidence of right heart dilatation was observed, indicating a low possibility of pulmonary embolism."1.43[A Case of Rocuronium-induced Anaphylaxis in Which Surgery was Subsequently Performed under General Anesthesia without Neuromuscular Blocking Agents]. ( Horiuchi, T; Saito, S; Takazawa, T, 2016)
"Any anaphylactoid reaction has to be systematically reported (e."1.29[Use of Diprivan in allergic patient]. ( Laxenaire, MC, 1994)
"A case of an anaphylactoid reaction following the induction of anaesthesia is reported."1.28Anaphylactoid reaction to propofol. ( Konieczko, K; McHale, SP, 1992)

Research

Studies (48)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.33)18.7374
1990's11 (22.92)18.2507
2000's12 (25.00)29.6817
2010's19 (39.58)24.3611
2020's2 (4.17)2.80

Authors

AuthorsStudies
Bayerl, C1
Del Prete, T1
Scarabelli, S1
Onuma, M1
Terada, M1
Ono, S1
Murakami, A1
Ishida, T1
Sano, T1
Yamaguchi, S1
Martínez, S1
Lasa, EM1
Joral, A1
Infante, S1
Perez, R1
Ibáñez, MD1
Anderson, BJ1
Sinclair, J1
Kounis, N1
Kounis, G1
Lee, SJ2
Bhatt, HV1
Frost, EA1
Horiuchi, T1
Takazawa, T1
Saito, S1
Richard, C1
Beaudouin, E1
Moneret-Vautrin, DA3
Kohler, C1
Nguyen-Grosjean, VM1
Jacquenet, S1
Same, M1
Smith, J2
Kuric, V1
Zaza, KJ1
Algazlan, SS1
Forshaw, N1
Cabaton, J1
Rondelet, B1
Gergele, L1
Besnard, C1
Piriou, V1
del Nogal Sáez, F1
Blasco Navalpotro, MA1
Jiménez Jiménez, J1
Seoane Leston, FJ1
Belso, N1
Kui, R1
Szegesdi, I1
Kakuja, M1
Kapitány, K1
Kemény, L1
Bata-Csörgo, Z1
Murphy, A1
Campbell, DE1
Baines, D1
Mehr, S1
Dewachter, P1
Mouton-Faivre, C1
Castells, MC1
Hepner, DL2
Kim, SI1
Jung, BI1
Lee, SM1
Kim, MG1
Park, SY1
Kim, SH1
Ok, SY1
Cochico, SG1
Baombe, JP1
Parvez, K1
Mertes, PM1
Laxenaire, MC5
Hofer, KN1
McCarthy, MW1
Buck, ML1
Hendrick, AE1
Marone, G1
Bova, M1
Detoraki, A1
Onorati, AM1
Rossi, FW1
Spadaro, G1
McNeill, O1
Kerridge, RK1
Boyle, MJ1
Glen, JB1
Hunter, SC1
Briggs, LP1
Clarke, RS1
Watkins, J1
Doenicke, A1
Lawes, EG1
Davis, A1
Hassoun, S1
Sabbah, A1
Drouet, M1
Cottineau, C1
Sánchez-Guerrero, IM1
Tortosa, JA1
Hernández-Palazón, J1
Escudero, AI1
Ducart, AR1
Watremez, C1
Louagie, YA1
Collard, EL1
Broka, SM1
Joucken, KL1
Konarzewski, W1
De'Ath, S1
Tsai, MH1
Kuo, PH1
Hong, RL1
Yang, PC1
Girgis, Y1
Kluger, MT1
Lewis, S1
Simpson, P1
Mata-Bermejo, E1
Gueant, JL2
McHale, SP1
Konieczko, K1
de Leon-Casasola, OA1
Weiss, A1
Lema, MJ1
McLeskey, CH1
Williamson, J1
Bermejo, E1
Mouton, C1
Navez, MT1
Naquib, M1

Reviews

2 reviews available for propofol and Anaphylaxis

ArticleYear
Anesthesia in the patient with multiple drug allergies: are all allergies the same?
    Current opinion in anaesthesiology, 2011, Volume: 24, Issue:3

    Topics: Analgesics; Anaphylaxis; Anesthesia; Anesthetics; Anesthetics, Intravenous; Animals; Anti-Bacterial

2011
Towards evidence-based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 1: is propofol safe in patients with egg anaphylaxis?
    Emergency medicine journal : EMJ, 2013, Volume: 30, Issue:1

    Topics: Anaphylaxis; Contraindications; Egg Hypersensitivity; Evidence-Based Emergency Medicine; Humans; Hyp

2013

Other Studies

46 other studies available for propofol and Anaphylaxis

ArticleYear
[Peri-Operative Anaphylaxis - Antiquated Customs and News Towards the Culprits].
    Laryngo- rhino- otologie, 2022, Volume: 101, Issue:11

    Topics: Anaphylaxis; Food Hypersensitivity; Humans; Mast Cells; Propofol

2022
A Suspected Anaphylactoid Reaction to Propofol in a Dog.
    Topics in companion animal medicine, 2021, Volume: 44

    Topics: Anaphylaxis; Anesthetics, Intravenous; Animals; Dog Diseases; Dogs; Female; Hysterectomy; Midazolam;

2021
Incidence of anaphylactic reactions after propofol administration in dogs.
    The Journal of veterinary medical science, 2017, Aug-18, Volume: 79, Issue:8

    Topics: Anaphylaxis; Anesthesia, General; Anesthetics, Intravenous; Animals; Dog Diseases; Dogs; Egg Hyperse

2017
[A Case of Anaphylactic Shock Immediately after Administration of Sugammadex].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:9

    Topics: Aged, 80 and over; Anaphylaxis; Epinephrine; Hemodynamics; Humans; Japan; Male; Propofol; Remifentan

2016
Recommendations for the Use of Propofol in Egg-Allergic Patients.
    Journal of investigational allergology & clinical immunology, 2019, Volume: 29, Issue:1

    Topics: Adult; Anaphylaxis; Anesthetics, Intravenous; Child; Egg Hypersensitivity; Humans; Hypnotics and Sed

2019
Food, fads, allergies and anaphylaxis with propofol.
    Anaesthesia, 2019, Volume: 74, Issue:10

    Topics: Anaphylaxis; Arachis; Child; Egg Hypersensitivity; Fabaceae; Glycine max; Humans; Propofol

2019
Anaphylactic cardiovascular collapse during anesthesia: the Kounis acute hypersensitivity syndrome seems to be the most likely cause.
    Journal of Korean medical science, 2013, Volume: 28, Issue:4

    Topics: Anaphylaxis; Anesthetics, Intravenous; Humans; Male; Propofol

2013
Suspected anaphylactic reaction associated with microemulsion propofol during anesthesia induction.
    Journal of Korean medical science, 2013, Volume: 28, Issue:4

    Topics: Anaphylaxis; Anesthetics, Intravenous; Humans; Male; Propofol

2013
Cardiovascular Collapse After Induction.
    Journal of neurosurgical anesthesiology, 2015, Volume: 27, Issue:3

    Topics: Adrenergic alpha-Agonists; Aged, 80 and over; Anaphylaxis; Anesthetics, Intravenous; Anti-Allergic A

2015
[A Case of Rocuronium-induced Anaphylaxis in Which Surgery was Subsequently Performed under General Anesthesia without Neuromuscular Blocking Agents].
    Masui. The Japanese journal of anesthesiology, 2016, Volume: 65, Issue:3

    Topics: Adult; Anaphylaxis; Androstanols; Anesthesia, General; Female; Humans; Neoplasm Recurrence, Local; N

2016
Severe anaphylaxis to Propofol: first case of evidence of sensitization to soy oil.
    European annals of allergy and clinical immunology, 2016, Volume: 48, Issue:3

    Topics: Allergens; Anaphylaxis; Food Hypersensitivity; Glycine max; Humans; Plant Oils; Propofol

2016
Should neuromuscular blockers be used for every paediatric intubation?
    British journal of hospital medicine (London, England : 2005), 2016, Volume: 77, Issue:6

    Topics: Analgesics, Opioid; Anaphylaxis; Anesthesiology; Anesthetics; Anesthetics, Inhalation; Anesthetics,

2016
Atypical presentation to rocuronium allergy in a 19-year-old female patient.
    Journal of clinical anesthesia, 2017, Volume: 37

    Topics: Adult; Anaphylaxis; Androstanols; Anesthesia, General; Anesthetics, Intravenous; Cardiopulmonary Res

2017
Is propofol safe to use in children with food allergies?
    British journal of hospital medicine (London, England : 2005), 2017, Mar-02, Volume: 78, Issue:3

    Topics: Anaphylaxis; Anesthetics, Intravenous; Child; Cross Reactions; Drug Hypersensitivity; Food Hypersens

2017
[Tako-Tsubo syndrome after anaphylaxis caused by succinylcholine during general anaesthesia].
    Annales francaises d'anesthesie et de reanimation, 2008, Volume: 27, Issue:10

    Topics: Anaphylaxis; Anesthesia, General; Anesthesia, Intravenous; Diabetes Mellitus, Type 2; Female; Gastro

2008
[Serious adverse reaction to diclofenac].
    Medicina intensiva, 2011, Volume: 35, Issue:3

    Topics: Anaphylaxis; Anticonvulsants; Cardiopulmonary Resuscitation; Coma; Combined Modality Therapy; Diclof

2011
Propofol and fentanyl induced perioperative anaphylaxis.
    British journal of anaesthesia, 2011, Volume: 106, Issue:2

    Topics: Adult; Anaphylaxis; Anesthetics, Intravenous; Fentanyl; Humans; Intraoperative Complications; Male;

2011
Allergic reactions to propofol in egg-allergic children.
    Anesthesia and analgesia, 2011, Volume: 113, Issue:1

    Topics: Adolescent; Anaphylaxis; Child; Child, Preschool; Drug Hypersensitivity; Egg Hypersensitivity; Egg W

2011
Suspected anaphylactic reaction associated with microemulsion propofol during anesthesia induction.
    Journal of Korean medical science, 2012, Volume: 27, Issue:7

    Topics: Adolescent; Anaphylaxis; Anesthetics, Intravenous; Bronchodilator Agents; Dexamethasone; Emulsions;

2012
Propofol allergy: assessing for patient risks.
    AORN journal, 2012, Volume: 96, Issue:4

    Topics: Anaphylaxis; Contraindications; Drug Hypersensitivity; Food Hypersensitivity; Humans; Hypnotics and

2012
Unrecognised fatal reaction to propofol or fentanyl.
    Anaesthesia, 2002, Volume: 57, Issue:8

    Topics: Anaphylaxis; Anesthetics; Fentanyl; Humans; Neuromuscular Blocking Agents; Propofol

2002
Possible anaphylaxis after propofol in a child with food allergy.
    The Annals of pharmacotherapy, 2003, Volume: 37, Issue:3

    Topics: Anaphylaxis; Child, Preschool; Drug Hypersensitivity; Drug Interactions; Egg Hypersensitivity; Human

2003
The human heart as a shock organ in anaphylaxis.
    Novartis Foundation symposium, 2004, Volume: 257

    Topics: Anaphylaxis; Atracurium; Autoantibodies; Cytokines; Heart; Histamine; Humans; Immunoglobulin E; Leuk

2004
Review of procedures for investigation of anaesthesia-associated anaphylaxis in Newcastle, Australia.
    Anaesthesia and intensive care, 2008, Volume: 36, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anaphylaxis; Anesthesia, General; Anesthetics; Anestheti

2008
Pharmacology of an emulsion formulation of ICI 35 868.
    British journal of anaesthesia, 1984, Volume: 56, Issue:6

    Topics: Anaphylaxis; Anesthetics; Animals; Behavior, Animal; Chemistry, Pharmaceutical; Dogs; Emulsions; Fem

1984
An adverse reaction to the administration of disoprofol (Diprivan).
    Anaesthesia, 1982, Volume: 37, Issue:11

    Topics: Adult; Anaphylaxis; Anesthesia, Intravenous; Anesthetics; Drug Hypersensitivity; Female; Humans; Phe

1982
Anaphylactoid or carcinoid crisis?
    British journal of anaesthesia, 1993, Volume: 71, Issue:4

    Topics: Anaphylaxis; Carcinoid Tumor; Female; Humans; Hydroxyindoleacetic Acid; Propofol; Succinylcholine

1993
[Use of Diprivan in allergic patient].
    Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:4

    Topics: Anaphylaxis; Anesthesia, Intravenous; Contraindications; Histamine Release; Humans; Hypersensitivity

1994
Is Atracurium contraindicated in patients with a known allergy to drugs?
    Anesthesiology, 1993, Volume: 78, Issue:3

    Topics: Anaphylaxis; Atracurium; Contraindications; Drug Hypersensitivity; Histamine Release; Humans; Propof

1993
Anaphylactoid reaction to propofol.
    Anaesthesia, 1993, Volume: 48, Issue:5

    Topics: Anaphylaxis; Epinephrine; Humans; Pneumonia, Aspiration; Propofol

1993
[Predictive value of the allergologic profile in anesthesia and resuscitation].
    Allergie et immunologie, 1998, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Anesthetics; Anesthetics, Intravenous; Bronchial Spasm; Child;

1998
Anaphylactoid reaction induced by pancuronium during general anaesthesia.
    European journal of anaesthesiology, 1998, Volume: 15, Issue:5

    Topics: Aged; Anaphylaxis; Anesthesia, Intravenous; Anesthetics, Intravenous; Bronchial Spasm; Humans; Hypot

1998
Propofol-induced anaphylactoid reaction during anesthesia for cardiac surgery.
    Journal of cardiothoracic and vascular anesthesia, 2000, Volume: 14, Issue:2

    Topics: Anaphylaxis; Anesthesia, Intravenous; Anesthetics, Intravenous; Angina, Unstable; Cardiac Surgical P

2000
Unrecognised fatal anaphylactic reaction to propofol or fentanyl.
    Anaesthesia, 2001, Volume: 56, Issue:5

    Topics: Anaphylaxis; Anesthetics, Intravenous; Fatal Outcome; Female; Fentanyl; Humans; Middle Aged; Propofo

2001
Anaphylaxis after propofol infusion for Port-A-Cath insertion in a 35-year old man.
    Journal of the Formosan Medical Association = Taiwan yi zhi, 2001, Volume: 100, Issue:6

    Topics: Adult; Anaphylaxis; Anesthesia, Intravenous; Anesthetics, Intravenous; Catheters, Indwelling; Humans

2001
Unrecognised fatal anaphylactic reaction to propofol or fentanyl.
    Anaesthesia, 2001, Volume: 56, Issue:10

    Topics: Anaphylaxis; Anesthetics, Intravenous; Fentanyl; Humans; Propofol

2001
The bispectral index during an anaphylactic circulatory arrest.
    Anaesthesia and intensive care, 2001, Volume: 29, Issue:5

    Topics: Anaphylaxis; Cardiopulmonary Resuscitation; Electroencephalography; Female; Heart Arrest; Humans; Mi

2001
Unrecognised anaphylaxis to propofol or fentanyl.
    Anaesthesia, 2001, Volume: 56, Issue:11

    Topics: Anaphylaxis; Anesthetics, Intravenous; Fentanyl; Humans; Neuromuscular Blocking Agents; Propofol

2001
Propofol-induced bronchoconstriction: asthma or allergy?
    Anesthesia and analgesia, 2002, Volume: 94, Issue:4

    Topics: Anaphylaxis; Anesthetics, Intravenous; Asthma; Bronchoconstriction; Diagnosis, Differential; Humans;

2002
Life-threatening anaphylactoid reactions to propofol (Diprivan)
    Anesthesiology, 1992, Volume: 77, Issue:2

    Topics: Adolescent; Adult; Aged; Anaphylaxis; Anesthesia, Intravenous; Basophils; Child; Female; Histamine R

1992
Anaphylactoid reaction to propofol.
    Anaesthesia, 1992, Volume: 47, Issue:10

    Topics: Anaphylaxis; Anesthesia, Intravenous; Drug Eruptions; Humans; Intradermal Tests; Male; Middle Aged;

1992
Anaphylaxis due to propofol.
    Anesthesiology, 1992, Volume: 77, Issue:2

    Topics: Anaphylaxis; Anesthesia, Intravenous; Female; Humans; Middle Aged; Propofol; Surgical Procedures, Op

1992
Anaphylactoid reactions following propofol-atracurium sequence.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1990, Volume: 37, Issue:8

    Topics: Anaphylaxis; Anesthesia, Intravenous; Atracurium; Humans; Infusions, Intravenous; Injections, Intrav

1990
Safe induction with propofol following thiopentone anaphylaxis.
    Anaesthesia and intensive care, 1990, Volume: 18, Issue:2

    Topics: Adult; Anaphylaxis; Anesthesia, Intravenous; Arthroscopy; Drug Hypersensitivity; Female; Humans; Pro

1990
Anaphylactic shock due to propofol.
    Lancet (London, England), 1988, Sep-24, Volume: 2, Issue:8613

    Topics: Aged; Anaphylaxis; Anesthetics; Epitopes; Humans; Male; Phenols; Propofol; Skin Tests

1988
Anaphylactoid reactions following propofol-atracurium sequence.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1989, Volume: 36, Issue:3 Pt 1

    Topics: Adolescent; Adult; Anaphylaxis; Anesthetics; Atracurium; Bronchial Spasm; Drug Eruptions; Drug Hyper

1989