Page last updated: 2024-11-03

propofol and Amnesia

propofol has been researched along with Amnesia in 33 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Amnesia: Pathologic partial or complete loss of the ability to recall past experiences (AMNESIA, RETROGRADE) or to form new memories (AMNESIA, ANTEROGRADE). This condition may be of organic or psychologic origin. Organic forms of amnesia are usually associated with dysfunction of the DIENCEPHALON or HIPPOCAMPUS. (From Adams et al., Principles of Neurology, 6th ed, pp426-7)

Research Excerpts

ExcerptRelevanceReference
"Propofol may produce amnesia by affecting encoding."9.13Low-dose propofol-induced amnesia is not due to a failure of encoding: left inferior prefrontal cortex is still active. ( Johnson, R; Mehta, M; Pan, H; Pryor, KO; Reinsel, RA; Veselis, RA, 2008)
"(1) 70%, 95% and 90% of patients manifested amnesia in propofol, midazolam and the combination group, respectively."9.13[Effects of combination of midazolam and propofol on anterograde amnesia in critical patients]. ( Dai, TJ; Li, JQ; Li, L; Li, MQ; Liu, J; Lu, F; Mo, X; Xu, JY; Xu, YJ; Zhang, Z, 2008)
"Propofol and midazolam are commonly used in the ICU to alleviate physical and psychological disturbances in consequence of anxiety."9.12Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety. ( Chen, FC; Hsiao, PC; Liaw, WJ; Tang, YY; Wang, KY; Yue-Cune Chang, YH, 2006)
" In contrast, a significant difference was observed at a sedation score of two; midazolam produced amnesia in more subjects than did propofol."9.12Amnesia for electric dental pulp stimulation and picture recall test under different levels of propofol or midazolam sedation. ( Ichinohe, T; Kaneko, Y; Matsuki, Y, 2007)
"Sixty adult patients were assigned to one of 3 groups according to the anesthetic technique chosen: isolfurane inhalation, propofol infusion at a higher rate, and propofol infusion at a lower rate supplemented with epidural anesthesia."9.08[Comparison of the amnesic effects of propofol and isoflurane anesthesia]. ( Maeshima, K; Ono, K, 1998)
" Propofol leads to amnesia, however, the mechanism remains unclear."7.83Inhibition of PARP-1 participates in the mechanisms of propofol-induced amnesia in mice and human. ( Jia, L; Lu, H; Luo, Y; Wang, W; Xue, Q; Yu, B; Zhang, F, 2016)
"The largest dose of bicuculline methiodide (100 pmol) not only blocked the propofol-induced amnesia but also reversed the inhibition effect of propofol on Arc protein expression in the hippocampus (P < 0."7.74Bilateral inhibition of gamma-aminobutyric acid type A receptor function within the basolateral amygdala blocked propofol-induced amnesia and activity-regulated cytoskeletal protein expression inhibition in the hippocampus. ( Ren, Y; Xue, QS; Yu, BW; Zhang, FJ; Zhao, X, 2008)
" In the current study, we test the hypothesis that the basolateral amygdala complex (BLAC) is a brain site involved with mediating propofol-induced amnesia."7.71Lesions of the basolateral amygdala complex block propofol-induced amnesia for inhibitory avoidance learning in rats. ( Alkire, MT; Cahill, L; Dickinson-Anson, H; Vazdarjanova, A; White, NS, 2001)
" We have evaluated the ability of nefiracetam, a novel cognition-enhancing agent, to alleviate propofol-induced amnesia in a rodent model of learning."7.70Nefiracetam prevents propofol-induced anterograde and retrograde amnesia in the rodent without compromising quality of anesthesia. ( Moriarty, DC; Murphy, KJ; O'Connell, AW; O'Gorman, DA; Regan, CM; Shiotani, T, 1998)
"Propofol is a short-acting, intravenous general anesthetic that is widely used in clinical practice for short procedures; however, it causes depressed cognitive function for several hours thereafter."5.40(R)-alpha-methylhistamine suppresses inhibitory neurotransmission in hippocampal CA1 pyramidal neurons counteracting propofol-induced amnesia in rats. ( Cheng, LZ; Li, WW; Raya, AD; Shi, XY; Tian, ML; Wang, Y; Zhang, H; Zou, Z, 2014)
"Propofol may produce amnesia by affecting encoding."5.13Low-dose propofol-induced amnesia is not due to a failure of encoding: left inferior prefrontal cortex is still active. ( Johnson, R; Mehta, M; Pan, H; Pryor, KO; Reinsel, RA; Veselis, RA, 2008)
"(1) 70%, 95% and 90% of patients manifested amnesia in propofol, midazolam and the combination group, respectively."5.13[Effects of combination of midazolam and propofol on anterograde amnesia in critical patients]. ( Dai, TJ; Li, JQ; Li, L; Li, MQ; Liu, J; Lu, F; Mo, X; Xu, JY; Xu, YJ; Zhang, Z, 2008)
"Propofol and midazolam are commonly used in the ICU to alleviate physical and psychological disturbances in consequence of anxiety."5.12Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety. ( Chen, FC; Hsiao, PC; Liaw, WJ; Tang, YY; Wang, KY; Yue-Cune Chang, YH, 2006)
"This prospective, randomized trial was designed to test the hypothesis that continuous infusion of low-dose remifentanil can provide effective analgesia, sedation, amnesia, patient comfort and stable recovery profile without respiratory depression when compared with propofol infusion during colonoscopy."5.12Can remifentanil be a better choice than propofol for colonoscopy during monitored anesthesia care? ( Akcaboy, EY; Akcaboy, ZN; Albayrak, D; Altinoren, B; Dikmen, B; Gogus, N, 2006)
" In contrast, a significant difference was observed at a sedation score of two; midazolam produced amnesia in more subjects than did propofol."5.12Amnesia for electric dental pulp stimulation and picture recall test under different levels of propofol or midazolam sedation. ( Ichinohe, T; Kaneko, Y; Matsuki, Y, 2007)
"As amnesia becomes maximal, rCBF reductions induced by propofol occur in brain regions identified with working memory processes."5.10A neuroanatomical construct for the amnesic effects of propofol. ( Dnistrian, AM; Feshchenko, VA; Reinsel, RA; Veselis, RA, 2002)
"Sixty adult patients were assigned to one of 3 groups according to the anesthetic technique chosen: isolfurane inhalation, propofol infusion at a higher rate, and propofol infusion at a lower rate supplemented with epidural anesthesia."5.08[Comparison of the amnesic effects of propofol and isoflurane anesthesia]. ( Maeshima, K; Ono, K, 1998)
" Propofol leads to amnesia, however, the mechanism remains unclear."3.83Inhibition of PARP-1 participates in the mechanisms of propofol-induced amnesia in mice and human. ( Jia, L; Lu, H; Luo, Y; Wang, W; Xue, Q; Yu, B; Zhang, F, 2016)
"The largest dose of bicuculline methiodide (100 pmol) not only blocked the propofol-induced amnesia but also reversed the inhibition effect of propofol on Arc protein expression in the hippocampus (P < 0."3.74Bilateral inhibition of gamma-aminobutyric acid type A receptor function within the basolateral amygdala blocked propofol-induced amnesia and activity-regulated cytoskeletal protein expression inhibition in the hippocampus. ( Ren, Y; Xue, QS; Yu, BW; Zhang, FJ; Zhao, X, 2008)
"Midazolam and propofol increased central serotonergic activity and provoked retrograde amnesia."3.73Facilitation of serotonergic activity and amnesia in rats caused by intravenous anesthetics. ( Adachi, N; Arai, T; Semba, K, 2005)
" In the current study, we test the hypothesis that the basolateral amygdala complex (BLAC) is a brain site involved with mediating propofol-induced amnesia."3.71Lesions of the basolateral amygdala complex block propofol-induced amnesia for inhibitory avoidance learning in rats. ( Alkire, MT; Cahill, L; Dickinson-Anson, H; Vazdarjanova, A; White, NS, 2001)
" We have evaluated the ability of nefiracetam, a novel cognition-enhancing agent, to alleviate propofol-induced amnesia in a rodent model of learning."3.70Nefiracetam prevents propofol-induced anterograde and retrograde amnesia in the rodent without compromising quality of anesthesia. ( Moriarty, DC; Murphy, KJ; O'Connell, AW; O'Gorman, DA; Regan, CM; Shiotani, T, 1998)
" The combination with fentanyl had a significantly lower effect on pulse rate and blood pressure."2.76Sedation, analgesia, and cardiorespiratory function in colonoscopy using midazolam combined with fentanyl or propofol. ( Shen, SR; Tang, WL; Wang, F; Xiao, DH; Xu, CX, 2011)
"Propofol proves to be an excellent sedative for therapeutic ERCP."2.71Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography. ( Chen, WX; Gu, Q; Gu, ZY; Li, YM; Lin, HJ; Yu, CH; Zhang, WF; Zhong, XQ, 2005)
"Thiopental has mild memory effects whereas fentanyl has none."2.68The comparative amnestic effects of midazolam, propofol, thiopental, and fentanyl at equisedative concentrations. ( Feshchenko, VA; Reinsel, RA; Veselis, RA; Wroński, M, 1997)
" Dosage was: propofol, bolus 1."2.67Total i.v. anaesthesia with propofol-alfentanil or propofol-fentanyl. ( Fruergård, K; Jenstrup, M; Møller, AM; Nielsen, J; Wiberg-Jørgensen, F, 1990)
" It also reviews the comparative pharmacokinetics, adverse effects, and dosing of ketamine, propofol, and ketofol as agents for procedural sedation and analgesia."2.48Ketamine, propofol, and ketofol use for pediatric sedation. ( Alletag, MJ; Auerbach, MA; Baum, CR, 2012)
"Propofol is a short-acting, intravenous general anesthetic that is widely used in clinical practice for short procedures; however, it causes depressed cognitive function for several hours thereafter."1.40(R)-alpha-methylhistamine suppresses inhibitory neurotransmission in hippocampal CA1 pyramidal neurons counteracting propofol-induced amnesia in rats. ( Cheng, LZ; Li, WW; Raya, AD; Shi, XY; Tian, ML; Wang, Y; Zhang, H; Zou, Z, 2014)
"As propofol has some amnesic properties, any instructions given to the patient postoperatively should be in writing."1.29[Recovery after anesthesia with Diprivan]. ( Nguyen, HN, 1994)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.03)18.7374
1990's8 (24.24)18.2507
2000's16 (48.48)29.6817
2010's8 (24.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sori, R1
Poojar, B1
Hodlur, N1
Gandigawad, P1
Kretschmannova, K1
Hines, RM1
Revilla-Sanchez, R1
Terunuma, M1
Tretter, V1
Jurd, R1
Kelz, MB1
Moss, SJ1
Davies, PA1
Li, WW1
Cheng, LZ1
Zou, Z1
Tian, ML1
Zhang, H1
Raya, AD1
Wang, Y1
Shi, XY1
Jia, L1
Wang, W1
Luo, Y1
Zhang, F1
Lu, H1
Xue, Q1
Yu, B1
Veselis, RA3
Pryor, KO1
Reinsel, RA3
Mehta, M1
Pan, H1
Johnson, R1
Xu, JY1
Li, MQ1
Zhang, Z1
Lu, F1
Li, L1
Li, JQ1
Mo, X1
Xu, YJ1
Liu, J1
Dai, TJ1
Ren, Y1
Zhang, FJ1
Xue, QS1
Zhao, X1
Yu, BW1
Eckle, VS1
Hucklenbruch, C1
Todorovic, SM1
Wang, F1
Shen, SR1
Xiao, DH1
Xu, CX1
Tang, WL1
Hemmings, HC1
Mackie, K1
Rinehart, JB1
Baker, B1
Raphael, D1
Alletag, MJ1
Auerbach, MA1
Baum, CR1
Feshchenko, VA2
Dnistrian, AM1
Chang, Y1
Huang, CH1
Wen, YR1
Chen, JY1
Wu, GJ1
Semba, K1
Adachi, N1
Arai, T1
Miner, JR1
Bachman, A1
Kosman, L1
Teng, B1
Heegaard, W1
Biros, MH1
Chen, WX1
Lin, HJ1
Zhang, WF1
Gu, Q1
Zhong, XQ1
Yu, CH1
Li, YM1
Gu, ZY1
Hsiao, PC1
Tang, YY1
Liaw, WJ1
Yue-Cune Chang, YH1
Chen, FC1
Wang, KY1
Akcaboy, ZN1
Akcaboy, EY1
Albayrak, D1
Altinoren, B1
Dikmen, B1
Gogus, N1
Matsuki, Y1
Ichinohe, T1
Kaneko, Y1
Fibuch, EE1
Wang, JQ1
Moller, DH1
Rampil, IJ1
Nguyen, HN1
Wessén, A1
Persson, PM1
Nilsson, A1
Hartvig, P1
Polster, MR1
Gray, PA1
O'Sullivan, G1
McCarthy, RA1
Park, GR1
Wroński, M1
Ono, K1
Maeshima, K1
O'Gorman, DA1
O'Connell, AW1
Murphy, KJ1
Moriarty, DC1
Shiotani, T1
Regan, CM1
Baker, GW1
Sleigh, JW1
Smith, P1
Alkire, MT1
Vazdarjanova, A1
Dickinson-Anson, H1
White, NS1
Cahill, L1
Schaer, H1
Prochacka, K1
Jenstrup, M1
Nielsen, J1
Fruergård, K1
Møller, AM1
Wiberg-Jørgensen, F1
Rupreht, J1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Neurotoxic Effect of Sevoflurane-Based Anaesthesia Guided by Significant Short-Term Olfactory Identification Impairment in Old Age[NCT03726580]600 participants (Actual)Observational [Patient Registry]2017-03-01Completed
[NCT02039453]160 participants (Anticipated)Interventional2013-09-30Recruiting
Midazolam With Meperidine and Dexmedetomidine vs Midazolam With Meperidine for Sedation During ERCP[NCT01404689]Phase 4110 participants (Actual)Interventional2011-08-31Completed
Etomidate With Meperidine vs Midazolam With Meperidine for Sedation During Endodscopic Retrograde Cholangiopancreatogram (ERCP)[NCT02027311]Phase 463 participants (Actual)Interventional2013-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Event of Hypoxia

Hypoxia defined as peripheral blood oxygen saturation measured by pulse oxymeter < 90% (NCT02027311)
Timeframe: Every 5min in Preoperative, intraoperative phase and 15 min in Recovery phase

InterventionHypoxia events (Number)
Midazolam19
Etomidate27

Number of Intervention

The frequency of intervention which was defined as any restraint of the patient's head, arms, or legs if they became agitated, or if patient movement was not controlled with verbal instruction from the endoscopist during the whole intraoperative phases. (NCT02027311)
Timeframe: Throughout the whole ERCP procedure

InterventionNumber of intervention (Mean)
Etomidate1.9
Midazolam7.5

Reviews

2 reviews available for propofol and Amnesia

ArticleYear
[What do we know about anesthetic mechanisms?: hypnosis, unresponsiveness to surgical incision and amnesia].
    Der Anaesthesist, 2009, Volume: 58, Issue:11

    Topics: Amnesia; Anesthesia; Anesthetics; Anesthetics, Dissociative; Anesthetics, Inhalation; Anesthetics, I

2009
Ketamine, propofol, and ketofol use for pediatric sedation.
    Pediatric emergency care, 2012, Volume: 28, Issue:12

    Topics: Adolescent; Amnesia; Analgesia; Analgesics, Non-Narcotic; Anesthetics, Dissociative; Antiemetics; An

2012

Trials

16 trials available for propofol and Amnesia

ArticleYear
Low-dose propofol-induced amnesia is not due to a failure of encoding: left inferior prefrontal cortex is still active.
    Anesthesiology, 2008, Volume: 109, Issue:2

    Topics: Adult; Amnesia; Cerebrum; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans;

2008
[Effects of combination of midazolam and propofol on anterograde amnesia in critical patients].
    Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue, 2008, Volume: 20, Issue:8

    Topics: Adolescent; Adult; Amnesia; Critical Illness; Drug Therapy, Combination; Female; Humans; Hypnotics a

2008
Sedation, analgesia, and cardiorespiratory function in colonoscopy using midazolam combined with fentanyl or propofol.
    International journal of colorectal disease, 2011, Volume: 26, Issue:6

    Topics: Amnesia; Analgesia; Blood Pressure; Colonoscopy; Demography; Drug Therapy, Combination; Female; Fent

2011
A neuroanatomical construct for the amnesic effects of propofol.
    Anesthesiology, 2002, Volume: 97, Issue:2

    Topics: Adult; Amnesia; Anesthetics, Intravenous; Brain; Conscious Sedation; Female; Humans; Male; Memory; N

2002
Assessment of the onset and persistence of amnesia during procedural sedation with propofol.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2005, Volume: 12, Issue:6

    Topics: Adult; Amnesia; Blood Gas Analysis; Conscious Sedation; Dose-Response Relationship, Drug; Humans; Hy

2005
Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2005, Volume: 4, Issue:3

    Topics: Adult; Aged; Amnesia; Blood Pressure; Case-Control Studies; Cholangiopancreatography, Endoscopic Ret

2005
Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2005, Volume: 4, Issue:3

    Topics: Adult; Aged; Amnesia; Blood Pressure; Case-Control Studies; Cholangiopancreatography, Endoscopic Ret

2005
Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2005, Volume: 4, Issue:3

    Topics: Adult; Aged; Amnesia; Blood Pressure; Case-Control Studies; Cholangiopancreatography, Endoscopic Ret

2005
Sedation and safety of propofol for therapeutic endoscopic retrograde cholangiopancreatography.
    Hepatobiliary & pancreatic diseases international : HBPD INT, 2005, Volume: 4, Issue:3

    Topics: Adult; Aged; Amnesia; Blood Pressure; Case-Control Studies; Cholangiopancreatography, Endoscopic Ret

2005
Postoperative sedation after major surgery with midazolam or propofol in the ICU: effects on amnesia and anxiety.
    Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists, 2006, Volume: 44, Issue:2

    Topics: Adult; Aged; Amnesia; Anxiety; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Male;

2006
Can remifentanil be a better choice than propofol for colonoscopy during monitored anesthesia care?
    Acta anaesthesiologica Scandinavica, 2006, Volume: 50, Issue:6

    Topics: Adolescent; Adult; Aged; Amnesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Carbon Dioxide;

2006
Amnesia for electric dental pulp stimulation and picture recall test under different levels of propofol or midazolam sedation.
    Acta anaesthesiologica Scandinavica, 2007, Volume: 51, Issue:1

    Topics: Adult; Amnesia; Conscious Sedation; Cross-Over Studies; Dental Care; Dental Pulp; Electric Stimulati

2007
Spectral entropy predicts auditory recall in volunteers.
    Anesthesia and analgesia, 2008, Volume: 106, Issue:3

    Topics: Adult; Amnesia; Auditory Perception; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Admi

2008
Concentration-effect relationships of propofol after total intravenous anesthesia.
    Anesthesia and analgesia, 1993, Volume: 77, Issue:5

    Topics: Adult; Alfentanil; Amnesia; Anesthesia Recovery Period; Anesthesia, Epidural; Anesthesia, Intravenou

1993
Comparison of the sedative and amnesic effects of midazolam and propofol.
    British journal of anaesthesia, 1993, Volume: 70, Issue:6

    Topics: Adolescent; Adult; Amnesia; Humans; Hypnotics and Sedatives; Memory; Midazolam; Propofol; Reaction T

1993
The comparative amnestic effects of midazolam, propofol, thiopental, and fentanyl at equisedative concentrations.
    Anesthesiology, 1997, Volume: 87, Issue:4

    Topics: Adult; Amnesia; Double-Blind Method; Female; Fentanyl; Humans; Hypnotics and Sedatives; Male; Memory

1997
[Comparison of the amnesic effects of propofol and isoflurane anesthesia].
    Masui. The Japanese journal of anesthesiology, 1998, Volume: 47, Issue:7

    Topics: Adult; Amnesia; Anesthesia; Anesthesia Recovery Period; Anesthesia, Epidural; Female; Humans; Isoflu

1998
[Recovery, amnesia and affective state following propofol in comparison with thiopental].
    Der Anaesthesist, 1990, Volume: 39, Issue:6

    Topics: Adult; Affect; Amnesia; Anesthesia Recovery Period; Anesthesia, Intravenous; Female; Humans; Middle

1990
Total i.v. anaesthesia with propofol-alfentanil or propofol-fentanyl.
    British journal of anaesthesia, 1990, Volume: 64, Issue:6

    Topics: Adult; Alfentanil; Amnesia; Anesthesia, Intravenous; Blood Pressure; Cognition; Drug Combinations; F

1990

Other Studies

15 other studies available for propofol and Amnesia

ArticleYear
Effect of Gmelina arborea on learning and memory in amnesia-induced and non-amnesia groups of albino Wistar rats.
    Journal of basic and clinical physiology and pharmacology, 2019, Jun-05, Volume: 30, Issue:5

    Topics: Amnesia; Animals; Avoidance Learning; Ethanol; Female; Fruit; Male; Maze Learning; Memory; Plant Ext

2019
Enhanced tonic inhibition influences the hypnotic and amnestic actions of the intravenous anesthetics etomidate and propofol.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013, Apr-24, Volume: 33, Issue:17

    Topics: Amnesia; Anesthetics, Intravenous; Animals; Etomidate; Female; Hippocampus; Hypnotics and Sedatives;

2013
(R)-alpha-methylhistamine suppresses inhibitory neurotransmission in hippocampal CA1 pyramidal neurons counteracting propofol-induced amnesia in rats.
    CNS neuroscience & therapeutics, 2014, Volume: 20, Issue:9

    Topics: Action Potentials; Amnesia; Anesthetics, Intravenous; Animals; CA1 Region, Hippocampal; Disease Mode

2014
Inhibition of PARP-1 participates in the mechanisms of propofol-induced amnesia in mice and human.
    Brain research, 2016, Apr-15, Volume: 1637

    Topics: Adult; Amnesia; Animals; Hippocampus; Humans; Male; Memory; Mice; Mice, Inbred C57BL; Poly (ADP-Ribo

2016
Bilateral inhibition of gamma-aminobutyric acid type A receptor function within the basolateral amygdala blocked propofol-induced amnesia and activity-regulated cytoskeletal protein expression inhibition in the hippocampus.
    Anesthesiology, 2008, Volume: 109, Issue:5

    Topics: Amnesia; Amygdala; Animals; Bicuculline; Cytoskeletal Proteins; Functional Laterality; GABA-A Recept

2008
The rivers of Lethe and Mnemosyne converge: propofol and memory consolidation.
    Anesthesiology, 2011, Volume: 114, Issue:6

    Topics: Amnesia; Animals; Humans; Memory; Propofol; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2;

2011
Postoperative global amnesia reversed with flumazenil.
    The neurologist, 2012, Volume: 18, Issue:4

    Topics: Amnesia; Analgesics; Anesthesia, General; Cholangiopancreatography, Endoscopic Retrograde; Desfluran

2012
Dissociative amnesia after general anesthesia--a case report.
    Acta anaesthesiologica Sinica, 2002, Volume: 40, Issue:2

    Topics: Adult; Amnesia; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Diagnosis

2002
Facilitation of serotonergic activity and amnesia in rats caused by intravenous anesthetics.
    Anesthesiology, 2005, Volume: 102, Issue:3

    Topics: Amnesia; Anesthetics, Intravenous; Animals; Avoidance Learning; Brain; Male; Microdialysis; Midazola

2005
Inhibition of the MAPK/ERK cascade: a potential transcription-dependent mechanism for the amnesic effect of anesthetic propofol.
    Neuroscience bulletin, 2007, Volume: 23, Issue:2

    Topics: Amnesia; Anesthetics, Intravenous; Animals; Cells, Cultured; Extracellular Signal-Regulated MAP Kina

2007
[Recovery after anesthesia with Diprivan].
    Annales francaises d'anesthesie et de reanimation, 1994, Volume: 13, Issue:4

    Topics: Amnesia; Anesthesia Recovery Period; Anesthesia, Intravenous; Drug Delivery Systems; Etomidate; Huma

1994
Nefiracetam prevents propofol-induced anterograde and retrograde amnesia in the rodent without compromising quality of anesthesia.
    Anesthesiology, 1998, Volume: 89, Issue:3

    Topics: Amnesia; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Cognition; Male; Propofol; Psyc

1998
Electroencephalographic indices related to hypnosis and amnesia during propofol anaesthesia for cardioversion.
    Anaesthesia and intensive care, 2000, Volume: 28, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amnesia; Anesthesia Recovery Period; Anesthesia, Intravenous; Anesth

2000
Lesions of the basolateral amygdala complex block propofol-induced amnesia for inhibitory avoidance learning in rats.
    Anesthesiology, 2001, Volume: 95, Issue:3

    Topics: Amnesia; Amygdala; Anesthetics, Intravenous; Animals; Avoidance Learning; Male; Memory; Propofol; Ra

2001
Awareness with amnesia during total intravenous anaesthesia with propofol.
    Anaesthesia, 1989, Volume: 44, Issue:12

    Topics: Adult; Amnesia; Anesthesia, Intravenous; Awareness; Cognition; Female; Humans; Intraoperative Compli

1989