propofol has been researched along with Amentia in 4 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients suffering from Alzheimer's disease, Parkinson's disease and dementia with Lewy bodies can be treated well with the cholinesterase inhibitors rivastigmine or donepezil, and because of the increasing number of these patients undergoing surgery in general anaesthesia we find it urgent to draw attention to possible complications such as severe bradycardia or third-degree heart block when propofol and remifentanil are being used." | 3.81 | [Severe bradycardia in general anaesthesia in a patient treated with cholinesterase inhibitors for dementia]. ( Ferguson, AH; Jellinge, ME, 2015) |
| "Patients with Huntington's disease develop a progressive but variable dementia." | 2.40 | Huntington's disease: review and anesthetic case management. ( Cangemi, CF; Miller, RJ, 1998) |
| "Patients with dementia are thought to be more sensitive to anesthesia, although volatile anesthetic requirement has not specifically been evaluated in this population." | 1.40 | Sensitivity to volatile anesthetics in patients with dementia: a case-control analysis. ( Dalton, JE; Geube, M; Kurz, A; Ontaneda, D; Perez-Protto, S; Sessler, DI, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perez-Protto, S | 1 |
| Geube, M | 1 |
| Ontaneda, D | 1 |
| Dalton, JE | 1 |
| Kurz, A | 1 |
| Sessler, DI | 1 |
| Jellinge, ME | 1 |
| Ferguson, AH | 1 |
| Ho, AM | 1 |
| Karmakar, MK | 1 |
| Cangemi, CF | 1 |
| Miller, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Prospective, Randomized, Blinded, Controlled Study Evaluating the Efficacy of Continuous Lumbar Plexus Block With and Without Parasacral Block in Patients Undergoing Total Hip Replacement[NCT02161484] | 10 participants (Actual) | Interventional | 2014-01-31 | Terminated (stopped due to The computer is crushed and all data is lost (IT was not able to recover it. Last data was collected 6.17.14)) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Complications such as drug toxicity, arrhythmia, bradycardia, hematoma, Foot Drop, allergic reaction will be recorded" (NCT02161484)
Timeframe: 48 hours after the start of the surgery
| Intervention | Number of complications (Number) |
|---|---|
| Continuous Lumbar Plexus Block With Parasacral Nerve Block | 0 |
| Lumbar Plexus Nerve Block | 0 |
Postoperative pain assessments using a 11-point numerical rating during physical therapy and at rest. This pain scale ranges from 0, being no pain at all, up to 10 being the worst pain ever experience. (NCT02161484)
Timeframe: 24 hours after the start of surgery
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pain at Rest | Pain with Movement | |
| Continuous Lumbar Plexus Block With Parasacral Nerve Block | 4.25 | 7.25 |
| Lumbar Plexus Nerve Block | 2.2 | 4.4 |
Postoperative pain assessments using a 11-point numerical rating during physical therapy and at rest. This pain scale ranges from 0, being no pain at all, up to 10 being the worst pain ever experience. (NCT02161484)
Timeframe: 48 hours after the start of surgery
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pain at Rest | Pain with Movement | |
| Continuous Lumbar Plexus Block With Parasacral Nerve Block | 1 | 8 |
| Lumbar Plexus Nerve Block | 2 | 5 |
Postoperative pain assessments using a 11-point numerical rating during physical therapy and at rest. This pain scale ranges from 0, being no pain at all, up to 10 being the worst pain ever experience. (NCT02161484)
Timeframe: 6 hours after the start of surgery
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Pain at Rest | Pain with Movement | |
| Continuous Lumbar Plexus Block With Parasacral Nerve Block | 2.6 | 3.5 |
| Lumbar Plexus Nerve Block | 3.6 | 5 |
1 review available for propofol and Amentia
| Article | Year |
|---|---|
Huntington's disease: review and anesthetic case management.
Topics: Aged; Analgesics, Opioid; Anesthesia, Dental; Anesthesia, General; Anesthetics, Inhalation; Anesthet | 1998 |
3 other studies available for propofol and Amentia
| Article | Year |
|---|---|
Sensitivity to volatile anesthetics in patients with dementia: a case-control analysis.
Topics: Aged; Aged, 80 and over; Anesthesia, General; Anesthetics, Inhalation; Case-Control Studies; Conscio | 2014 |
[Severe bradycardia in general anaesthesia in a patient treated with cholinesterase inhibitors for dementia].
Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Bradycardia; Cholinesterase Inhibitors; Dementi | 2015 |
Combined paravertebral lumbar plexus and parasacral sciatic nerve block for reduction of hip fracture in a patient with severe aortic stenosis.
Topics: Aged; Aged, 80 and over; Anesthesia, Spinal; Anesthetics, Intravenous; Aortic Valve Stenosis; Dement | 2002 |