propofol has been researched along with Alloxan Diabetes in 11 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We hypothesized that propofol, an anesthetic with antioxidant capacity, may attenuate hyperglycemia-induced oxidative stress in cardiomyocytes via enhancing heme oxygenase-1 activation and ameliorate hyperglycemia-induced cardiac hypertrophy and apoptosis via heme oxygenase-1/signal transducer and activator of transcription 3 signaling and improve cardiac function in diabetes." | 7.80 | Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats. ( Cheung, CW; Clanachan, AS; Fang, X; Hung, V; Irwin, MG; Lei, S; Li, H; Mao, X; Wong, GT; Xia, Z; Xia, ZY; Xu, J, 2014) |
| " We hypothesized that propofol, an anesthetic with antioxidant capacity, may attenuate hyperglycemia-induced oxidative stress in cardiomyocytes via enhancing heme oxygenase-1 activation and ameliorate hyperglycemia-induced cardiac hypertrophy and apoptosis via heme oxygenase-1/signal transducer and activator of transcription 3 signaling and improve cardiac function in diabetes." | 3.80 | Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats. ( Cheung, CW; Clanachan, AS; Fang, X; Hung, V; Irwin, MG; Lei, S; Li, H; Mao, X; Wong, GT; Xia, Z; Xia, ZY; Xu, J, 2014) |
| "Propofol has been reported to have an inhibitory effect on ischemia/reperfusion (I/R) injury in various experimental models by reducing oxidative stress, protecting mitochondrial function and suppressing apoptosis." | 1.39 | Effect and mechanism of propofol on myocardial ischemia reperfusion injury in type 2 diabetic rats. ( Deng, L; Ding, W; Gu, J; Li, D; Li, W; Lin, C; Sui, H; Yang, X; Yang, Y, 2013) |
| " In the pharmacokinetic study, propofol was administered intravenously at 6 mg kg(-1) min(-1) for 2 min." | 1.33 | Altered dose-to-effect of propofol due to pharmacokinetics in rats with experimental diabetes mellitus. ( Agrad, FZ; Calvo, R; de la Fuente, L; Leal, N; Lukas, JC; Suarez, E, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 4 (36.36) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Facey, J | 1 |
| Young, L | 1 |
| Nwokocha, C | 1 |
| Lin, C | 1 |
| Sui, H | 1 |
| Gu, J | 1 |
| Yang, X | 1 |
| Deng, L | 1 |
| Li, W | 1 |
| Ding, W | 1 |
| Li, D | 1 |
| Yang, Y | 1 |
| Xu, J | 1 |
| Li, H | 1 |
| Irwin, MG | 1 |
| Xia, ZY | 1 |
| Mao, X | 1 |
| Lei, S | 1 |
| Wong, GT | 1 |
| Hung, V | 1 |
| Cheung, CW | 1 |
| Fang, X | 1 |
| Clanachan, AS | 1 |
| Xia, Z | 1 |
| Li Volti, G | 1 |
| Murabito, P | 1 |
| Comu, FM | 1 |
| Ozturk, L | 1 |
| Alkan, M | 1 |
| Pampal, K | 1 |
| Arslan, M | 1 |
| Isik, B | 1 |
| Atac, MS | 1 |
| Yilmaz, D | 1 |
| Crespo, MJ | 1 |
| Marrero, M | 1 |
| Cruz, N | 1 |
| Quidgley, J | 1 |
| Creagh, O | 1 |
| Torres, H | 1 |
| Rivera, K | 1 |
| Leal, N | 1 |
| Calvo, R | 1 |
| Agrad, FZ | 1 |
| Lukas, JC | 1 |
| de la Fuente, L | 1 |
| Suarez, E | 1 |
| Wickley, PJ | 2 |
| Shiga, T | 2 |
| Murray, PA | 2 |
| Damron, DS | 2 |
| Ohsawa, M | 1 |
| Kamei, J | 1 |
| Chen, TL | 1 |
| Chang, HC | 1 |
| Chen, TG | 1 |
| Tai, YT | 1 |
| Chen, RM | 1 |
11 other studies available for propofol and Alloxan Diabetes
| Article | Year |
|---|---|
Relaxation Responses of Ketamine and Propofol to Vasoactive Agents in Streptozotocin-Induced Diabetic Rats.
Topics: Acetylcholine; Animals; Diabetes Mellitus, Experimental; Endothelium, Vascular; Ketamine; Oxidative | 2020 |
Effect and mechanism of propofol on myocardial ischemia reperfusion injury in type 2 diabetic rats.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cytoprotection; Diabetes Mellitus, Experi | 2013 |
Propofol ameliorates hyperglycemia-induced cardiac hypertrophy and dysfunction via heme oxygenase-1/signal transducer and activator of transcription 3 signaling pathway in rats.
Topics: Activating Transcription Factor 3; Animals; Antioxidants; Apoptosis; Cardiomegaly; Diabetes Mellitus | 2014 |
Pharmacologic induction of heme oxygenase-1: it is time to take it seriously*.
Topics: Activating Transcription Factor 3; Animals; Cardiomegaly; Diabetes Mellitus, Experimental; Diabetes | 2014 |
Investigation of the effects of propofol and vitamin C administration on erythrocyte deformability in rats with streptozotocin-induced diabetes mellitis.
Topics: Animals; Ascorbic Acid; Diabetes Mellitus, Experimental; Erythrocyte Deformability; Humans; Male; Pr | 2014 |
Diabetes alters cardiovascular responses to anaesthetic induction agents in STZ-diabetic rats.
Topics: Anesthetics; Animals; Blood Glucose; Cardiac Output; Diabetes Complications; Diabetes Mellitus, Expe | 2011 |
Altered dose-to-effect of propofol due to pharmacokinetics in rats with experimental diabetes mellitus.
Topics: Anesthetics, Intravenous; Animals; Blood Glucose; Blood Proteins; Brain; Cholesterol; Chromatography | 2005 |
Propofol decreases myofilament Ca2+ sensitivity via a protein kinase C-, nitric oxide synthase-dependent pathway in diabetic cardiomyocytes.
Topics: Actin Cytoskeleton; Anesthetics, Intravenous; Animals; Blood Glucose; Calcium Signaling; Diabetes Me | 2006 |
Propofol modulates Na+-Ca2+ exchange activity via activation of protein kinase C in diabetic cardiomyocytes.
Topics: Animals; Blood Glucose; Calcium; Diabetes Mellitus, Experimental; Enzyme Activation; Male; Myocytes, | 2007 |
Modification of the effect of diazepam on the propofol-induced loss of the righting reflex in mice by diabetes.
Topics: Anesthetics, Intravenous; Animals; Diabetes Mellitus, Experimental; Diazepam; Flumazenil; GABA Modul | 1999 |
Modulation of cytochrome P-450 dependent monooxygenases in streptozotocin-induced diabetic hamster: I. Effects of propofol on defluorination and cytochrome P-450 activities.
Topics: Animals; Cricetinae; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme Inhibitors; Diabetes Mellitus, | 2000 |