propofol has been researched along with Alcoholism in 16 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Alcoholism: A primary, chronic disease with genetic, psychosocial, and environmental factors influencing its development and manifestations. The disease is often progressive and fatal. It is characterized by impaired control over drinking, preoccupation with the drug alcohol, use of alcohol despite adverse consequences, and distortions in thinking, most notably denial. Each of these symptoms may be continuous or periodic. (Morse & Flavin for the Joint Commission of the National Council on Alcoholism and Drug Dependence and the American Society of Addiction Medicine to Study the Definition and Criteria for the Diagnosis of Alcoholism: in JAMA 1992;268:1012-4)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thirty male patients (alcoholic group; n = 30) with chronic alcoholism and 30 patients (control group; n = 30) with a history of small alcohol intake were anaesthetized with propofol and remifentanil by target-controlled infusion." | 7.77 | Chronic alcoholism increases the induction dose of propofol. ( Chen, J; Gu, W; Liang, C; Wang, H; Xue, Z, 2011) |
| "The doses of propofol that produce loss of consciousness were investigated in 26 patients with chronic alcoholism and in 20 patients with a history of small alcoholic intake undergoing ear, nose, and throat surgery under general anesthesia." | 7.68 | Chronic alcoholism increases the induction dose of propofol in humans. ( Desmonts, JM; Farinotti, R; Fassoulaki, A; Servin, F, 1993) |
| "Fifty patients with chronic alcoholism scheduled for elective ERCP were randomized 1:1 to receive dexmedetomidine (Dex group) (loading dose 1 μg kg(-1) over 10 min, followed by constant intravenous infusion 0." | 5.17 | Dexmedetomidine impairs success of patient-controlled sedation in alcoholics during ERCP: a randomized, double-blind, placebo-controlled study. ( Halttunen, J; Kylänpää, L; Lindström, O; Mazanikov, M; Mustonen, H; Pöyhiä, R; Udd, M, 2013) |
| "Chronic alcoholism induces only mild changes in the pharmacokinetics of propofol." | 5.10 | Pharmacokinetics of propofol administered by target-controlled infusion to alcoholic patients. ( Bougeois, B; Desmonts, JM; Farinotti, R; Gomeni, R; Mentré, F; Servin, FS, 2003) |
| "Thirty male patients (alcoholic group; n = 30) with chronic alcoholism and 30 patients (control group; n = 30) with a history of small alcohol intake were anaesthetized with propofol and remifentanil by target-controlled infusion." | 3.77 | Chronic alcoholism increases the induction dose of propofol. ( Chen, J; Gu, W; Liang, C; Wang, H; Xue, Z, 2011) |
| "The doses of propofol that produce loss of consciousness were investigated in 26 patients with chronic alcoholism and in 20 patients with a history of small alcoholic intake undergoing ear, nose, and throat surgery under general anesthesia." | 3.68 | Chronic alcoholism increases the induction dose of propofol in humans. ( Desmonts, JM; Farinotti, R; Fassoulaki, A; Servin, F, 1993) |
| "Propofol is a viable alternative for patients refractory to benzodiazepines; however, the role of other agents remains unclear." | 2.53 | Treatment of Severe Alcohol Withdrawal. ( Cadiz, M; Doshi, MR; Holzhausen, JM; Natavio, A; Schmidt, KJ; Winegardner, JE, 2016) |
| "Bradycardia was experienced by 11." | 1.56 | Use of Propofol Plus Dexmedetomidine in Patients Experiencing Severe Alcohol Withdrawal in the Intensive Care Unit. ( Love, K; Zimmermann, AE, 2020) |
| "propofol was not significantly different between ethanol-treated and control rats." | 1.32 | Chronic ethanol consumption does not affect action of propofol on rat hippocampal acetylcholine release in vivo. ( Andoh, T; Inagawa, G; Kikuchi, T; Koyama, Y; Nishihama, M; Sato, K; Shioda, M; Yamada, Y, 2004) |
| "Propofol was administered intravenously." | 1.29 | Behavioral effects and pharmacokinetics of propofol in rats selected for differential ethanol sensitivity. ( Deitrich, RA; Fay, T; Liu, Y, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (6.25) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Love, K | 1 |
| Zimmermann, AE | 1 |
| Fernández, S | 1 |
| Castro, P | 1 |
| Nogué, S | 1 |
| Nicolás, JM | 1 |
| Schmidt, KJ | 1 |
| Doshi, MR | 1 |
| Holzhausen, JM | 1 |
| Natavio, A | 1 |
| Cadiz, M | 1 |
| Winegardner, JE | 1 |
| Long, D | 1 |
| Long, B | 1 |
| Koyfman, A | 1 |
| Liang, C | 1 |
| Chen, J | 1 |
| Gu, W | 1 |
| Wang, H | 1 |
| Xue, Z | 1 |
| Mazanikov, M | 1 |
| Udd, M | 1 |
| Kylänpää, L | 1 |
| Mustonen, H | 1 |
| Lindström, O | 1 |
| Halttunen, J | 1 |
| Pöyhiä, R | 1 |
| Elmas, T | 1 |
| Mavioglu, O | 1 |
| Oztekin, S | 1 |
| Elar, Z | 1 |
| Guven, H | 1 |
| Servin, FS | 1 |
| Bougeois, B | 1 |
| Gomeni, R | 1 |
| Mentré, F | 1 |
| Farinotti, R | 2 |
| Desmonts, JM | 2 |
| Subramaniam, K | 1 |
| Gowda, RM | 1 |
| Rosa, U | 1 |
| Inagawa, G | 1 |
| Sato, K | 1 |
| Kikuchi, T | 1 |
| Nishihama, M | 1 |
| Shioda, M | 1 |
| Koyama, Y | 1 |
| Yamada, Y | 1 |
| Andoh, T | 1 |
| González González, G | 1 |
| Yanes Vidal, G | 1 |
| Marenco de la Fuente, ML | 1 |
| Liu, Y | 1 |
| Fay, T | 1 |
| Deitrich, RA | 1 |
| Schnorf, H | 1 |
| Landis, T | 1 |
| Brimacombe, J | 1 |
| Fassoulaki, A | 1 |
| Servin, F | 1 |
| du Cailar, J | 1 |
| d'Athis, F | 1 |
| Eledjam, JJ | 1 |
| Bonnet, MC | 1 |
2 reviews available for propofol and Alcoholism
| Article | Year |
|---|---|
Treatment of Severe Alcohol Withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Critical Care; Dexmedetomidine; Drug Thera | 2016 |
The emergency medicine management of severe alcohol withdrawal.
Topics: Alcohol Withdrawal Delirium; Alcoholism; Benzodiazepines; Critical Care; Dose-Response Relationship, | 2017 |
3 trials available for propofol and Alcoholism
| Article | Year |
|---|---|
Dexmedetomidine impairs success of patient-controlled sedation in alcoholics during ERCP: a randomized, double-blind, placebo-controlled study.
Topics: Alcoholism; Alfentanil; Anesthetics, Intravenous; Cholangiopancreatography, Endoscopic Retrograde; C | 2013 |
The effect of propofol (anesthetic and inhibitor of CYP3A4) on serum lidocaine concentrations in smokers and chronic alcohol consumers.
Topics: Adult; Aged; Alcoholism; Anesthetics; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cy | 2003 |
Pharmacokinetics of propofol administered by target-controlled infusion to alcoholic patients.
Topics: Adolescent; Adult; Aged; Alcoholism; Anesthesia Recovery Period; Anesthetics, Intravenous; Bayes The | 2003 |
11 other studies available for propofol and Alcoholism
| Article | Year |
|---|---|
Use of Propofol Plus Dexmedetomidine in Patients Experiencing Severe Alcohol Withdrawal in the Intensive Care Unit.
Topics: Alcoholism; Bradycardia; Critical Care; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; | 2020 |
[Green urine due to propofol].
Topics: Alcoholism; Color; Conscious Sedation; Consciousness Disorders; Diagnosis, Differential; Dibenzothia | 2013 |
Chronic alcoholism increases the induction dose of propofol.
Topics: Adult; Alcoholism; Anesthetics, Intravenous; Dose-Response Relationship, Drug; Electroencephalograph | 2011 |
Delayed neuroexcitatory symptoms following propofol sedation in a patient with polysubstance abuse.
Topics: Akathisia, Drug-Induced; Alcoholism; Conscious Sedation; Electroencephalography; Humans; Hypnotics a | 2003 |
Chronic ethanol consumption does not affect action of propofol on rat hippocampal acetylcholine release in vivo.
Topics: Acetylcholine; Alcoholism; Anesthetics, Intravenous; Animals; Chromatography, High Pressure Liquid; | 2004 |
[Eclampsia in a pregnant drug addict].
Topics: Adult; Alcoholism; Cocaine; Cocaine-Related Disorders; Eclampsia; Epilepsy, Tonic-Clonic; Female; Hu | 2006 |
Behavioral effects and pharmacokinetics of propofol in rats selected for differential ethanol sensitivity.
Topics: Alcoholism; Animals; Female; Hypnotics and Sedatives; Male; Metabolic Clearance Rate; Phenotype; Pro | 1995 |
Motor neuron disease after enflurane/propofol anaesthesia in patient with alcohol abuse.
Topics: Aged; Alcoholism; Anesthesia, General; Enflurane; Ethanol; Female; Follow-Up Studies; Humans; Motor | 1995 |
An extreme case of resistance to anaesthetic agents.
Topics: Adult; Alcoholism; Anesthesia, Inhalation; Anesthesia, Intravenous; Drug Resistance; Fentanyl; Halot | 1994 |
Chronic alcoholism increases the induction dose of propofol in humans.
Topics: Adult; Alcoholism; Anesthesia, General; Chronic Disease; Dose-Response Relationship, Drug; Drug Tole | 1993 |
[Propofol and alcoholism].
Topics: Adult; Alcoholism; Anesthesia, General; Anesthetics; Female; Humans; Male; Middle Aged; Phenols; Pro | 1987 |