Page last updated: 2024-11-03

propofol and Airway Obstruction

propofol has been researched along with Airway Obstruction in 82 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Airway Obstruction: Any hindrance to the passage of air into and out of the lungs.

Research Excerpts

ExcerptRelevanceReference
"The probability of each sedation and airway obstruction score was properly described using a sigmoid Emax model with a narrow therapeutic range of propofol Ce in OSAHS patients."7.81Pharmacodynamic Estimate of Propofol-Induced Sedation and Airway Obstruction Effects in Obstructive Sleep Apnea-Hypopnea Syndrome. ( Han, DW; Jeong, KH; Kang, YR; Kim, SY; Koo, BN; Shin, S, 2015)
" All patients had received initial anesthesia with inhaled sevoflurane."7.80A retrospective study of anesthesia during rigid bronchoscopy for airway foreign body removal in children: propofol and sevoflurane with spontaneous ventilation. ( Chai, J; Chen, WM; Han, N; Wang, LY; Wu, XY, 2014)
" This study reports a population pharmacodynamic model of propofol sedation and airway obstruction in the Parkinson disease population."7.71Modeling of the sedative and airway obstruction effects of propofol in patients with Parkinson disease undergoing stereotactic surgery. ( Carrero, E; Fábregas, N; Gambús, PL; Nalda-Felipe, MA; Rapado, J; Salvador, L; Trocóniz, IF; Valero, R, 2002)
"Upper airway obstruction during sleep can trigger compensatory neuromuscular responses and/or prolong inspiration in order to maintain adequate minute ventilation."6.74The compensatory responses to upper airway obstruction in normal subjects under propofol anesthesia. ( Ayuse, T; Hoshino, Y; Kirkness, JP; Kurata, S; Oi, K; Patil, SP; Schneider, H; Schwartz, AR, 2009)
"The incidence of airway obstruction during induction of anesthesia was higher (34% vs 10%, P < 0."6.67Propofol anesthesia reduces emesis and airway obstruction in pediatric outpatients. ( Bargas, MS; Martin, TM; Nicolson, SC, 1993)
" In the control group, patients were anesthetized with propofol, while patients in the experimental group received propofol combined with 2% lidocaine spray for topical pharyngeal anesthesia."5.69Application of topical pharyngeal anesthesia to reduce adverse reactions during painless gastroscopy: A prospective randomized study. ( Hu, S; Lin, X; Liu, Y; Song, C; Sun, H; Yu, Y, 2023)
"Twenty-one patients with obstructive sleep apnea underwent polysomnography and sleep endoscopy during zolpidem-induced sleep and during DISE with propofol."5.56Comparison of upper airway obstruction during zolpidem-induced sleep and propofol-induced sleep in patients with obstructive sleep apnea: a pilot study. ( Cahali, MB; Genta, PR; Grad, GF; Lorenzi-Filho, G; Ordones, AB; Sennes, LU, 2020)
"These observations suggest that dexmedetomidine sedation does not inherently protect against upper airway obstruction."5.30Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study. ( Eastwood, PR; Eriksson, LI; Fagerlund, MJ; Hillman, DR; Lawther, BK; Lodenius, Å; Maddison, KJ; Scheinin, M; Walsh, JH, 2019)
" We compare AIAE rates (coughing, gagging, apnea, airway obstruction, and laryngospasm) in children who received TPA as part of their propofol-based procedural sedation for EGD with those who did not receive TPA."4.31Topical Pharyngeal Anesthesia in Sedated Pediatric Patients Undergoing Esophagogastroduodenoscopy. ( Aljabari, S; El-Halabi, I; Friedman, S; Ohler, A; Tryon, C; Waheed, S, 2023)
"We did not find a significant difference in the degree of upper airway obstruction on DISE in children sedated with propofol versus dexmedetomidine."4.02Propofol versus dexmedetomidine during drug-induced sleep endoscopy (DISE) for pediatric obstructive sleep apnea. ( Chervin, RD; Henderson, LM; Hoi, K; Kirkham, EM; Leis, AM; Melendez, JB; Puglia, MP, 2021)
" Propofol is a commonly used sedative for magnetic resonance imaging in pediatric patients, but patients who receive it may exhibit dose-dependent upper airway obstruction and respiratory depression."3.88A retrospective comparison of propofol to dexmedetomidine for pediatric magnetic resonance imaging sedation in patients with mucopolysaccharidosis type II. ( Gil, NS; Hahm, TS; Jeong, JS; Kang, R; Oh, YN; Shin, YH, 2018)
"The addition of a dexmedetomidine infusion prior to our propofol MRI sedation protocol resulted in fewer sedation-related adverse events, particularly upper airway obstruction."3.85A retrospective comparison of propofol alone to propofol in combination with dexmedetomidine for pediatric 3T MRI sedation. ( Boriosi, JP; Eickhoff, JC; Hollman, GA; Klein, KB, 2017)
"The probability of each sedation and airway obstruction score was properly described using a sigmoid Emax model with a narrow therapeutic range of propofol Ce in OSAHS patients."3.81Pharmacodynamic Estimate of Propofol-Induced Sedation and Airway Obstruction Effects in Obstructive Sleep Apnea-Hypopnea Syndrome. ( Han, DW; Jeong, KH; Kang, YR; Kim, SY; Koo, BN; Shin, S, 2015)
" All patients had received initial anesthesia with inhaled sevoflurane."3.80A retrospective study of anesthesia during rigid bronchoscopy for airway foreign body removal in children: propofol and sevoflurane with spontaneous ventilation. ( Chai, J; Chen, WM; Han, N; Wang, LY; Wu, XY, 2014)
" This study reports a population pharmacodynamic model of propofol sedation and airway obstruction in the Parkinson disease population."3.71Modeling of the sedative and airway obstruction effects of propofol in patients with Parkinson disease undergoing stereotactic surgery. ( Carrero, E; Fábregas, N; Gambús, PL; Nalda-Felipe, MA; Rapado, J; Salvador, L; Trocóniz, IF; Valero, R, 2002)
"We assessed the impact of DISE on the treatment plan of snoring patients."2.79Drug-induced sleep endoscopy changes snoring management plan very significantly compared to standard clinical evaluation. ( De Medts, J; Delsupehe, KG; Pilaete, K, 2014)
"Propofol infusion was used for induction and to maintain blood at a constant target concentration between 1."2.76Effect of head elevation on passive upper airway collapsibility in normal subjects during propofol anesthesia. ( Ayuse, T; Hoshino, Y; Kirkness, JP; Kobayashi, M; Kurata, S; Moromugi, S; Oi, K; Schneider, H; Schwartz, AR, 2011)
"Subjects with obstructive sleep apnea unable to tolerate positive airway pressure therapy."2.75Interrater reliability of drug-induced sleep endoscopy. ( Goldberg, AN; Kezirian, EJ; Ma, W; Malhotra, A; McCulloch, CE; White, DP, 2010)
"Upper airway obstruction (UAO) during sedation can often cause clinically significant adverse events."2.72Differences between midazolam and propofol sedation on upper airway collapsibility using dynamic negative airway pressure. ( Bailey, P; Karan, S; Norton, JR; Palmer, L; Rackovsky, O; Varlese, A; Voter, WA; Ward, DS, 2006)
"We found that the incidence of partial airway obstruction needing intraoperative airway manipulation was higher with the laryngeal tube than with the laryngeal mask airway."2.71The use of modified VBM laryngeal tube compared to Laryngeal Mask Airway during spontaneous ventilation. ( Chan, L; Chiu, CL; Murugasu, J, 2003)
"Complete airway obstruction occurred in one patient after insertion of the device and in two patients during maintenance of anaesthesia."2.69The cuffed oropharyngeal airway. Its clinical use in 100 patients. ( Asai, T; Jones, RM; Koga, K; Latto, IP; Stacey, M; Vaughan, RS, 1998)
"Coughing and airway obstruction were both significantly reduced by pretreatment with lignocaine, as was the incidence of failure of insertion requiring deepening of anaesthesia (p < 0."2.68Facilitation of laryngeal mask insertion. Effects of lignocaine given intravenously before induction with propofol. ( Bree, SE; Sneyd, JR; Stoneham, MD, 1995)
" We conclude that the laryngeal mask provides a safe and effective form of airway management for infants and children in the hands of supervised anaesthesia trainees both for spontaneous and controlled ventilation using either isoflurane or total intravenous anaesthesia."2.68Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children. ( Alvarez, M; Brimacombe, J; Lopez-Gil, M, 1996)
"After opening the Boyle-Davis gag, airway obstruction occurred in ten patients (18."2.67Anaesthesia for adenotonsillectomy: a comparison between tracheal intubation and the armoured laryngeal mask airway. ( Au, A; Cook, MJ; Dain, S; Ganapathy, S; Morley-Forster, PK; Ruby, R; Webster, AC, 1993)
"The incidence of airway obstruction during induction of anesthesia was higher (34% vs 10%, P < 0."2.67Propofol anesthesia reduces emesis and airway obstruction in pediatric outpatients. ( Bargas, MS; Martin, TM; Nicolson, SC, 1993)
"In children with persistent obstructive sleep apnea after adenotonsillectomy, the most common sites of obstruction were the adenoids (54."1.62Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea. ( Adónis, C; Freire, F; Loureiro, HC; Menezes, M; Raposo, D; Rito, J; Trindade-Soares, M, 2021)
"Twenty-one patients with obstructive sleep apnea underwent polysomnography and sleep endoscopy during zolpidem-induced sleep and during DISE with propofol."1.56Comparison of upper airway obstruction during zolpidem-induced sleep and propofol-induced sleep in patients with obstructive sleep apnea: a pilot study. ( Cahali, MB; Genta, PR; Grad, GF; Lorenzi-Filho, G; Ordones, AB; Sennes, LU, 2020)
"PE1 group had a higher incidence of muscle spasm, body moving, choking, and deglutition."1.56Clinical observation of the combined use of propofol and etomidate in painless gastroscopy. ( Hao, L; Hu, X; Huang, X; Kang, F; Li, W; Zhu, B, 2020)
" So far, a dose-response relationship between sedation and collapsibility has not been demonstrated."1.43Depth-dependent changes of obstruction patterns under increasing sedation during drug-induced sedation endoscopy: results of a German monocentric clinical trial. ( Herzog, B; Herzog, M; Kellner, P; Kühnel, T; Plontke, S; Plößl, S; Rohrmeier, C; Wanzek, R, 2016)
"All of the patients had positional obstructive sleep apnea (OSA)."1.43Drug-induced sleep endoscopy in children with Prader-Willi syndrome. ( Chen, YC; Chiu, TJ; Hsu, YB; Huang, TT; Lan, MC; Lan, MY; Tsai, LP; Wong, SB, 2016)
"Overall, there were few SAEs, and airway obstruction was the most common SAE."1.43Complications of Deep Sedation for Individual Procedures (Lumbar Puncture Alone) Versus Combined Procedures (Lumbar Puncture and Bone Marrow Aspirate) in Pediatric Oncology Patients. ( Kamat, PP; McCracken, CE; Patel, MM; Simon, HK, 2016)
"A retrospective chart review of OSAHS patients who underwent DISE at our institution during the 2006-2010 period was conducted."1.42Drug-induced sedation endoscopy versus clinical exploration for the diagnosis of severe upper airway obstruction in OSAHS patients. ( Agostini Porras, G; Carrasco Llatas, M; Dalmau Galofre, J; Zerpa Zerpa, V, 2015)
"Severe airway obstruction was defined as >75% collapse on endoscopy."1.39Drug-induced sleep endoscopy vs awake Müller's maneuver in the diagnosis of severe upper airway obstruction. ( Badr, MS; Folbe, AJ; Lin, HS; Rowley, JA; Soares, D; Yoo, G, 2013)
"Residual upper airway obstruction in surgery nonresponders likely occurs due to multiple mechanisms, and DISE may enhance the understanding of them."1.37Nonresponders to pharyngeal surgery for obstructive sleep apnea: insights from drug-induced sleep endoscopy. ( Kezirian, EJ, 2011)
"Partial airway obstruction was observed in 4 patients but manual lifting of the jaw was enough to free the partial obstruction and dental treatment was uneventfully conducted."1.35Office-based ambulatory sedation--the use of the airway protector system during oral surgery: a prospective audit of the first 100 patients. ( Bodner, L; Klein, M; Weksler, D; Weksler, N, 2008)
"Although the incidence of respiratory depression was higher in patients receiving deep sedation with propofol than in patients who were lightly sedated (17."1.32Use of deep intravenous sedation with propofol and the laryngeal mask airway during transesophageal echocardiography. ( Arens, J; Ferson, D; Sapire, K; Sinha, A; Swafford, J; Thakar, D, 2003)
"In no case was laryngospasm or total airway obstruction observed."1.31Additional clinical observations utilizing bispectral analysis. ( Sandler, NA, 2000)

Research

Studies (82)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's13 (15.85)18.2507
2000's19 (23.17)29.6817
2010's43 (52.44)24.3611
2020's7 (8.54)2.80

Authors

AuthorsStudies
Zhang, W1
Yin, H1
Xu, Y1
Fang, Z1
Wang, W1
Zhang, C1
Shi, H1
Wang, X1
Aljabari, S1
Ohler, A1
Waheed, S1
El-Halabi, I1
Tryon, C1
Friedman, S1
Lin, X2
Sun, H1
Liu, Y1
Hu, S1
Yu, Y1
Song, C1
Lodenius, Å1
Maddison, KJ2
Lawther, BK1
Scheinin, M1
Eriksson, LI1
Eastwood, PR3
Hillman, DR4
Fagerlund, MJ1
Walsh, JH2
Ordones, AB1
Grad, GF1
Cahali, MB1
Lorenzi-Filho, G1
Sennes, LU1
Genta, PR1
Raposo, D1
Menezes, M1
Rito, J1
Trindade-Soares, M1
Adónis, C1
Loureiro, HC1
Freire, F1
Kirkham, EM1
Hoi, K1
Melendez, JB1
Henderson, LM1
Leis, AM1
Puglia, MP1
Chervin, RD1
Hao, L1
Hu, X1
Zhu, B1
Li, W1
Huang, X1
Kang, F1
Hsu, YS1
Jacobowitz, O1
Lee, JJ1
Ford, MD1
Tobey, AB1
Jabbour, N1
Constable, N1
Thomas, C1
Jones, M1
Walters, M1
Kang, R1
Shin, YH1
Gil, NS1
Oh, YN1
Hahm, TS1
Jeong, JS1
Aiello, L1
Corso, RM1
Bellantonio, D1
Maitan, S1
Vanderveken, OM3
Maurer, JT1
Hohenhorst, W3
Hamans, E3
Lin, HS2
Vroegop, AV2
Anders, C1
de Vries, N2
Van de Heyning, PH2
Yasir, M1
Khan, FA1
Boudewyns, AN1
Scholman, J1
Saldien, V1
Wouters, K1
Braem, MJ1
Cavaliere, M1
Russo, F1
Iemma, M1
Pilaete, K1
De Medts, J1
Delsupehe, KG1
De Vito, A1
Carrasco Llatas, M2
Vanni, A1
Bosi, M1
Braghiroli, A1
Campanini, A1
Kotecha, BT1
Maurer, J1
Montevecchi, F1
Piccin, O1
Sorrenti, G1
Vicini, C1
Aktas, O1
Erdur, O1
Cirik, AA1
Kayhan, FT1
Quante, M1
Merkenschlager, A1
Kiess, W1
Horn, IS1
Kyas, D1
Dietz, A1
Fischer, M1
Shepherd, KL1
Baker, VA1
Lawther, B1
Platt, P1
Chai, J1
Wu, XY1
Han, N1
Wang, LY1
Chen, WM1
Herzog, M2
Plößl, S2
Glien, A1
Herzog, B2
Rohrmeier, C2
Kühnel, T2
Plontke, S2
Kellner, P2
Moustafa, MA1
Emara, DM1
Nouh, MR1
Blumen, MB1
Latournerie, V1
Bequignon, E1
Guillere, L1
Chabolle, F1
Verse, T1
Koo, BN1
Shin, S1
Kim, SY2
Kang, YR1
Jeong, KH1
Han, DW1
Zerpa Zerpa, V1
Agostini Porras, G1
Dalmau Galofre, J1
Eich, C1
Funke, OR1
Patel, MM1
Kamat, PP1
McCracken, CE1
Simon, HK1
Kurata, S4
Sanuki, T1
Okayasu, I1
Kawai, M2
Moromugi, S2
Ayuse, T5
Lan, MC1
Hsu, YB1
Lan, MY1
Chiu, TJ1
Huang, TT1
Wong, SB1
Chen, YC1
Tsai, LP1
Wanzek, R1
Kandil, A1
Subramanyam, R1
Hossain, MM1
Ishman, S1
Shott, S1
Tewari, A1
Mahmoud, M1
Boriosi, JP1
Eickhoff, JC1
Klein, KB1
Hollman, GA1
Watt, S1
Sabouri, S1
Hegazy, R1
Gupta, P1
Heard, C1
Hybášková, J1
Jor, O1
Novák, V1
Zeleník, K1
Matoušek, P1
Komínek, P1
Kim, KN1
Lee, HJ1
Kim, JY1
Hoshino, Y3
Schneider, H3
Kirkness, JP3
Patil, SP2
Schwartz, AR5
Oi, K3
Kempen, PM1
Fernández, E1
Martínez, I1
Martín, B1
Valero, A1
Gerónimo Pardo, M1
Mateo Cerdán, CM1
Moreno Salcedo, JM1
Kezirian, EJ2
White, DP1
Malhotra, A1
Ma, W1
McCulloch, CE1
Goldberg, AN1
Friedberg, BL1
Overdyk, FJ1
Mueller, MF1
Baughman, VL1
Paisansathan, C1
Kobayashi, M2
Papaioannou, A1
Mathioudakis, E1
Nyktari, V1
Astyrakaki, E1
Sgourou, K1
Askitopoulou, H1
Soares, D1
Folbe, AJ1
Yoo, G1
Badr, MS1
Rowley, JA2
Fábregas, N1
Rapado, J1
Gambús, PL1
Valero, R1
Carrero, E1
Salvador, L1
Nalda-Felipe, MA1
Trocóniz, IF1
Chiu, CL1
Murugasu, J1
Chan, L1
Ferson, D1
Thakar, D1
Swafford, J1
Sinha, A1
Sapire, K1
Arens, J1
McGill, F1
Shobha, R1
Stacey, M2
Turley, A1
Hall, JE1
Koomen, E1
Poortmans, G1
Anderson, BJ1
Janssens, MM1
Platt, PR1
Shepherd, K1
Maddison, K1
Norton, JR1
Ward, DS1
Karan, S1
Voter, WA1
Palmer, L1
Varlese, A1
Rackovsky, O1
Bailey, P1
Kotsev, S1
Gueret, G1
Billard, V1
Bourgain, JL1
Chang, LC1
Kuczkowski, KM1
Disma, N1
Astuto, M1
Giorgio, AD1
Russo, G1
Klein, M1
Weksler, N1
Weksler, D1
Bodner, L1
Monclus, E1
Garcés, A1
Artés, D1
Mabrock, M1
Stoneham, MD1
Bree, SE1
Sneyd, JR1
Lawson, R1
Hickey, S1
Webster, AC1
Morley-Forster, PK1
Dain, S1
Ganapathy, S1
Ruby, R1
Au, A1
Cook, MJ1
Martin, TM1
Nicolson, SC1
Bargas, MS1
Mayor, AH1
Willey, SJ1
Gillespie, MB1
Smith, PL1
Robotham, JL1
Mathru, M1
Esch, O1
Lang, J1
Herbert, ME1
Chaljub, G1
Goodacre, B1
vanSonnenberg, E1
Lewer, BM1
Torrance, JM1
Lopez-Gil, M1
Brimacombe, J1
Alvarez, M1
Ludbrook, GL1
Hitchcock, M1
Upton, RN1
Conacher, ID1
Paes, LL1
McMahon, CC1
Morritt, GN1
Asai, T1
Koga, K1
Jones, RM1
Latto, IP1
Vaughan, RS1
Okazaki, J1
Isono, S1
Tanaka, A1
Tagaito, Y1
Nishino, T1
Cameron, AJ1
Sellers, WF1
Sandler, NA1
Mamaya, B1
Abernethy, LJ1
Allan, PL1
Drummond, GB1
Mignone, L1
Villani, L1
Zappi, L1
Paglia, A1
Mereu, C1
Ivaldi, P1
Verna, A1

Clinical Trials (13)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison Between Natural Sleep Endoscopy and Drug-induced Sleep Endoscopy Among Obstructive Sleep Apnea Subjects Referred for Surgical Treatment[NCT03004014]28 participants (Actual)Interventional2015-01-31Completed
Trial of Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea[NCT05303987]Phase 290 participants (Anticipated)Interventional2022-10-05Recruiting
Propofol and Etomidate Admixtures Comparisons Trial (PEAC Trial)[NCT05358535]Phase 3200 participants (Anticipated)Interventional2022-09-19Recruiting
The Role of Drug-Induced Sleep Endoscopy for the Optimisation of Treatment of Patients With Obstruction Sleep Apnoea[NCT02855515]120 participants (Actual)Interventional2016-05-31Completed
Propofolsleep - A Observational Study on Cardiopulmonary and Pharyngeal Reactions While Drug Induced Sleep Endoscopy in Patients With Obstructive Sleep Apnea Syndrome Under PSI Monitoring[NCT03224936]20 participants (Anticipated)Observational2017-08-22Active, not recruiting
An Observer-blinded Randomized Study of Propofol Infusion vs Bolus Dexmedetomidine and Propofol Sedation for Pediatric Magnetic Resonance Imaging[NCT03513757]Phase 440 participants (Actual)Interventional2018-03-04Completed
Drug-Induced Sleep Endoscopy for Upper Airway Evaluation in Obstructive Sleep Apnea[NCT00695214]Phase 2800 participants (Anticipated)Interventional2004-02-29Suspended (stopped due to Transfer to another institution)
Supraglottic Airway Use for Transesophageal Echocardiography: a Safe Alternative to Deep Sedation for Patients With High-risk Cardiopulmonary Disease. (SGA-TEE)[NCT04939220]110 participants (Anticipated)Interventional2024-02-29Not yet recruiting
Incidence and Nature of Respiratory Impairment in Consecutive Patients Undergoing Bronchoscopy Under Conscious Sedation: A Pilot Study[NCT03886454]33 participants (Actual)Observational2017-06-19Completed
Effect of Increasing Depth of Dexmedetomidine and Propofol Anesthesia on Upper Airway Morphology in Children With History of Obstructive Sleep Apnea[NCT01344759]Phase 460 participants (Actual)Interventional2009-06-30Completed
A Comparison of Different Ventilation Strategies in Children Using the Proseal™ Laryngeal Mask Airway[NCT00966433]33 participants (Actual)Interventional2009-08-31Completed
The Safety and Efficacy of Supraglottic Airway Use in Children[NCT02202174]10,000 participants (Anticipated)Observational2014-06-30Recruiting
Comparison of Weight-based Versus External Ear-size Based Technique for Selection of Laryngeal Mask Airway in Pediatric Surgical Patients.[NCT03931122]136 participants (Anticipated)Interventional2019-12-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Delirium

Pediatric Anesthesia Emergence Delirium (PAED) score greater than 12 as defined by Sikich and Lerman. 0 = no delirium, 20 = worst possible delirium; 5 categories scored from 0-4 additive for a maximum score of 20. Categories 1-3 are scored the same and categories ar scored inversely as described. 1. Child makes contact with caregiver, 2. child's actions are purposeful, 3. child is aware of his surroundings. For each of these category, score 0 for extremely, 1 for very much, 2 for quite a bit, 3 for just a little, 4 for not at all. The other 2 categories 4. Child is restless and 5 Child is inconsolable are scored as 0 for not at all, 1 for just a little, 2 for quite a bit, 3 for very much, 4 for extremely (NCT03513757)
Timeframe: up to 24 hours.

Interventionparticipants (Number)
Propofol0
Propofol Dexmedetomidine0

Dexmedetomidine Dose

dexmedetomidine dose (mcg/kg) (NCT03513757)
Timeframe: up to 90 minutes

Interventionmcg/kg (Median)
Propofol0
Propofol Dexmedetomidine0.70

Discharge Ready

minutes from completion of scan to discharge ready (NCT03513757)
Timeframe: up to 2 hours

Interventionminutes (Median)
Propofol40
Propofol Dexmedetomidine17

Efficiency of Propofol Dexmedetomidine Sedation Compared With Propofol Infusion

Time (minutes) from anesthesia start to readiness for discharge from the department to home or clinic. (NCT03513757)
Timeframe: through study completion, an average of 2 hours

Interventionminutes (Median)
Propofol98
Propofol Dexmedetomidine77

Eye Opening

minutes from completion of scan to spontaneous eye opening (NCT03513757)
Timeframe: up to 90 minutes

Interventionminutes (Median)
Propofol28
Propofol Dexmedetomidine3

Glycopyrrolate Dose

glycopyrrolate dose (mcg/kg) (NCT03513757)
Timeframe: 5 minutes

Interventionmcg/kg (Median)
Propofol0
Propofol Dexmedetomidine4.2

Irritability

behavior deemed inappropriate and a deviation from child's normal though parental observation obtained through follow-up phone call (NCT03513757)
Timeframe: up to 48 hours

Interventionparticipants (Number)
Propofol3
Propofol Dexmedetomidine0

Lidocaine Dose

lidocaine dose (mg/kg) (NCT03513757)
Timeframe: up to 90 minutes

Interventionmg/kg (Median)
Propofol1.00
Propofol Dexmedetomidine1.00

Nitrous Oxide

documentation of use (NCT03513757)
Timeframe: up to 10 minutes

Interventionparticipants (Number)
Propofol18
Propofol Dexmedetomidine17

Oral/Enteral Intake

minutes from completion of scan to oral/enteral intake (NCT03513757)
Timeframe: up to 2 hours

Interventionminutes (Median)
Propofol33
Propofol Dexmedetomidine14

Sevoflurane

sevoflurane induction time of 5 minutes (NCT03513757)
Timeframe: sevoflurane induction time up to 10 minutes

Interventionparticipants (Number)
Propofol18
Propofol Dexmedetomidine17

Sleep Pattern

parental observation of deviation from child's normal habit obtained through follow-up phone call (NCT03513757)
Timeframe: up to 48 hours

Interventionparticipants (Number)
Propofol3
Propofol Dexmedetomidine2

Total Propofol Administered

total propofol administered (mg/kg) (NCT03513757)
Timeframe: up to 90 minutes

Interventionmg/kg (Median)
Propofol10.6
Propofol Dexmedetomidine3.0

Needed Artificial Airway

This is the count of the number of patients who needed an artificial airway. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes

InterventionNumber of artifical airway events (Number)
Mild OSA and Dexmedetomidine0
Mild OSA and Propofol1
Moderate OSA and Dexmedetomidine1
Moderate OSA and Propofol1
Severe OSA and Dexmedetomidine2
Severe OSA and Propofol5

Obstructive Index Until Recovery Room Discharge

The Obstructive Index is a count of the obstructive apnea events per hour of sleep (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes

InterventionApnea events/hour of sleep (Mean)
Mild OSA and Dexmedetomidine4.2
Mild OSA and Propofol3.0
Moderate OSA and Dexmedetomidine8.0
Moderate OSA and Propofol8.0
Severe OSA and Dexmedetomidine16.7
Severe OSA and Propofol17.1

Respiratory Disturbance Index

The respiratory disturbance index is a count of respiratory disturbance events per hour of sleep. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes

Interventionrespir.disturbance events/hr of sleep (Mean)
Mild OSA and Dexmedetomidine5.1
Mild OSA and Propofol3.2
Moderate OSA and Dexmedetomidine8.8
Moderate OSA and Propofol7.1
Severe OSA and Dexmedetomidine16.6
Severe OSA and Propofol25.2

Room Air SpO2

The patient's oxygen saturation on room air. (NCT01344759)
Timeframe: During MRI and until recovery room discharge - approximately 30-250 minutes

Interventionpercentage of SpO2 (Mean)
Mild OSA and Dexmedetomidine87.2
Mild OSA and Propofol88.0
Moderate OSA and Dexmedetomidine86.3
Moderate OSA and Propofol89.0
Severe OSA and Dexmedetomidine84.0
Severe OSA and Propofol88.0

Cross Sectional Area of the Pharyngeal Airway

The primary outcome measures will be the cross sectional area of the pharyngeal airway of the patients measured at two levels soft palate (nasopharyngeal) and base of the tongue (retroglossal). Magnetic resonance images of the airway were obtained during low (1 mcg/kg/hr) and high (3 mcg/kg/hr) doses of DEX or low (100 mcg/kg/m) and high (200 mcg/kg/m) doses of Propofol. All were administered through an intravenous (IV) catheter. (NCT01344759)
Timeframe: during MRI within first 10 minutes of scanning

,
Interventionmm^2 (Median)
Low Dose Sedative, Nasopharyngeal measurementHigh Dose Sedative, Nasopharyngeal measurementLow Dose Sedative, Retroglossal measurementHigh dose sedative, Retroglossal measurement
Dexmedetomidine178.5235.4120.9120.5
Propofol239.9201.6115.1108.1

Differences in End-tidal Carbon Dioxide Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups.

Differences in End-tidal Carbon Dioxide Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups will be calculated by subtracting the mean of End-tidal Carbon Dioxide from the PSV group to the SV group (NCT00966433)
Timeframe: up to 90 minutes

InterventionmmHg (Mean)
Spontaneous Ventilation55.2
Pressure Support Ventilation47

Differences in Respiratory Rates Between Spontaneous Ventilation and Pressure Support Ventilation Groups.

Differences in respiratory rates between spontaneous ventilation and pressure support ventilation groups will be calculated by subtracting the mean of from the respiratory rates PSV group to the SV group. (NCT00966433)
Timeframe: up to 90 minutes

Interventionbreath/min (Mean)
Spontaneous Ventilation28.1
Pressure Support Ventilation14.2

Differences Tidal Volume Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups.

Tidal Volume Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups. Measured in mL/Kg and will be calculated by subtracting the mean of tidal volume from the PSV group to the SV group (NCT00966433)
Timeframe: up to 90 minutes

InterventionmL/kg (Mean)
Spontaneous Ventilation4.0
Pressure Support Ventilation7.6

Mean Tidal Volume Values Compared Between SV and PCV Groups

Mean Tidal Volume Values compared between SV and PCV Groups. Measured in mL/kg (NCT00966433)
Timeframe: up to 90 minutes

InterventionmL/kg (Mean)
Spontaneous Ventilation4.0
Pressure Control Ventilation7.6

Mean Values of ETCO2 Between the PSV and PCV Groups

Mean Values of ETCO2 between the PSV and PCV Groups. Measured in mmHg (NCT00966433)
Timeframe: up to 90 minutes

InterventionmmHg (Mean)
Pressure Support Ventilation47.0
Pressure Control Ventilation43.1

Mean Values of ETCO2 in SV and PCV Groups

Mean Values of ETCO2 in SV and PCV groups reported in mmHg (NCT00966433)
Timeframe: up to 90 minutes

InterventionmmHg (Mean)
Spontaneous Ventilation55.2
Pressure Control Ventilation43.1

Mean Values of Respiratory Rate Compared Between Pressure Support Ventilation and Pressure Control Ventilation Groups.

(NCT00966433)
Timeframe: up to 90 minutes

Interventionbreath/min (Mean)
Pressure Support Ventilation14.2
Pressure Control Ventilation21.2

Mean Values of Respiratory Rate Compared Between the Spontaneous Ventilation and Pressure Control Ventilation Groups.

(NCT00966433)
Timeframe: up to 90 minutes

Interventionbreath/min (Mean)
Spontaneous Ventilation28.1
Pressure Control Ventilation21.2

Mean Values of Tidal Volume Between the PSV and PCV Groups

Mean Values of Tidal Volume Between the PSV and PCV Groups. Measured in mL/kg (NCT00966433)
Timeframe: up to 90 minutes

InterventionmL/kg (Mean)
Pressure Support Ventilation7.6
Pressure Control Ventilation7.6

Trials

23 trials available for propofol and Airway Obstruction

ArticleYear
The effect of varying inhaled oxygen concentrations of high-flow nasal cannula oxygen therapy during gastroscopy with propofol sedation in elderly patients: a randomized controlled study.
    BMC anesthesiology, 2022, 11-02, Volume: 22, Issue:1

    Topics: Aged; Airway Obstruction; Cannula; Gastroscopy; Humans; Hypoxia; Oxygen; Oxygen Inhalation Therapy;

2022
Application of topical pharyngeal anesthesia to reduce adverse reactions during painless gastroscopy: A prospective randomized study.
    Technology and health care : official journal of the European Society for Engineering and Medicine, 2023, Volume: 31, Issue:4

    Topics: Airway Obstruction; Anesthesia; Anesthetics, Intravenous; Gastroscopy; Humans; Propofol; Prospective

2023
Upper Airway Collapsibility during Dexmedetomidine and Propofol Sedation in Healthy Volunteers: A Nonblinded Randomized Crossover Study.
    Anesthesiology, 2019, Volume: 131, Issue:5

    Topics: Adult; Aged; Airway Obstruction; Cross-Over Studies; Dexmedetomidine; Female; Healthy Volunteers; Hu

2019
LMA Gastro Airway® Cuff Pilot for endoscopic retrograde cholangiopancreatography: a preliminary experience.
    Minerva anestesiologica, 2019, Volume: 85, Issue:7

    Topics: Aged; Airway Management; Airway Obstruction; Anesthesia, General; Cholangiopancreatography, Endoscop

2019
Drug-induced sleep endoscopy changes snoring management plan very significantly compared to standard clinical evaluation.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2014, Volume: 271, Issue:5

    Topics: Adolescent; Adult; Aged; Airway Obstruction; Anesthesia, Intravenous; Continuous Positive Airway Pre

2014
Effects on upper airway collapsibility of presence of a pharyngeal catheter.
    Journal of sleep research, 2015, Volume: 24, Issue:1

    Topics: Adult; Airway Obstruction; Anesthesiology; Body Mass Index; Catheters; Female; Humans; Male; Pharynx

2015
A pilot study of upper airway management using a remote-controlled artificial muscle device during propofol anesthesia.
    Journal of clinical anesthesia, 2016, Volume: 29

    Topics: Adult; Airway Management; Airway Obstruction; Airway Resistance; Anesthesia, Intravenous; Anesthetic

2016
Combined use of dexmedetomidine and propofol in monitored anesthesia care: a randomized controlled study.
    BMC anesthesiology, 2017, 03-01, Volume: 17, Issue:1

    Topics: Airway Obstruction; Blood Pressure; Bradycardia; Dexmedetomidine; Double-Blind Method; Drug Therapy,

2017
The compensatory responses to upper airway obstruction in normal subjects under propofol anesthesia.
    Respiratory physiology & neurobiology, 2009, Mar-31, Volume: 166, Issue:1

    Topics: Adolescent; Adult; Airway Obstruction; Airway Resistance; Anesthetics, Intravenous; Blood Pressure;

2009
Interrater reliability of drug-induced sleep endoscopy.
    Archives of otolaryngology--head & neck surgery, 2010, Volume: 136, Issue:4

    Topics: Adult; Aged; Airway Obstruction; Endoscopy; Female; Humans; Hypnotics and Sedatives; Male; Middle Ag

2010
Effect of head elevation on passive upper airway collapsibility in normal subjects during propofol anesthesia.
    Anesthesiology, 2011, Volume: 115, Issue:2

    Topics: Adult; Airway Obstruction; Anesthesia, Intravenous; Anesthetics, Intravenous; Dose-Response Relation

2011
The effects of hormonal status on upper airway patency in normal female subjects during propofol anesthesia.
    Journal of clinical anesthesia, 2011, Volume: 23, Issue:7

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Consciousness Monitors; Electromyography; Femal

2011
The use of modified VBM laryngeal tube compared to Laryngeal Mask Airway during spontaneous ventilation.
    Anaesthesia and intensive care, 2003, Volume: 31, Issue:2

    Topics: Adult; Airway Obstruction; Anesthesia, General; Anesthetics, Intravenous; Equipment Design; Female;

2003
Clinical assessment of use of the Airway Management Device (AMD).
    European journal of anaesthesiology, 2004, Volume: 21, Issue:2

    Topics: Airway Obstruction; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Intravenous; Equip

2004
Differences between midazolam and propofol sedation on upper airway collapsibility using dynamic negative airway pressure.
    Anesthesiology, 2006, Volume: 104, Issue:6

    Topics: Adult; Air Pressure; Airway Obstruction; Electroencephalography; Female; Humans; Hypnotics and Sedat

2006
Fibre-optic intubation teaching in sedated patients with anticipated difficult intubation.
    European journal of anaesthesiology, 2007, Volume: 24, Issue:3

    Topics: Airway Obstruction; Anesthesia, General; Anesthesiology; Anesthetics, Intravenous; Conscious Sedatio

2007
Facilitation of laryngeal mask insertion. Effects of lignocaine given intravenously before induction with propofol.
    Anaesthesia, 1995, Volume: 50, Issue:5

    Topics: Adult; Airway Obstruction; Blood Pressure; Cough; Double-Blind Method; Female; Gagging; Heart Rate;

1995
Anaesthesia for adenotonsillectomy: a comparison between tracheal intubation and the armoured laryngeal mask airway.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1993, Volume: 40, Issue:12

    Topics: Adenoidectomy; Airway Obstruction; Anesthesia, General; Blood Loss, Surgical; Blood Pressure; Bronch

1993
Propofol anesthesia reduces emesis and airway obstruction in pediatric outpatients.
    Anesthesia and analgesia, 1993, Volume: 76, Issue:1

    Topics: Airway Obstruction; Ambulatory Surgical Procedures; Anesthesia, Inhalation; Child; Child, Preschool;

1993
Magnetic resonance imaging of the upper airway. Effects of propofol anesthesia and nasal continuous positive airway pressure in humans.
    Anesthesiology, 1996, Volume: 84, Issue:2

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Female; Humans; Magnetic Resonance Imaging; Mal

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
Safety and efficacy of the laryngeal mask airway. A prospective survey of 1400 children.
    Anaesthesia, 1996, Volume: 51, Issue:10

    Topics: Adolescent; Airway Obstruction; Anesthesia, General; Child; Child, Preschool; Female; Humans; Infant

1996
The cuffed oropharyngeal airway. Its clinical use in 100 patients.
    Anaesthesia, 1998, Volume: 53, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Airway Obstruction; Anesthesia, General; Anesthetics, In

1998
Early vs late LMA removal; risks to patients and damage to equipment.
    Anaesthesia and intensive care, 2001, Volume: 29, Issue:1

    Topics: Aged; Airway Obstruction; Anesthesia Recovery Period; Anesthesia, Inhalation; Bite Force; Child, Pre

2001

Other Studies

59 other studies available for propofol and Airway Obstruction

ArticleYear
Topical Pharyngeal Anesthesia in Sedated Pediatric Patients Undergoing Esophagogastroduodenoscopy.
    Journal of pediatric gastroenterology and nutrition, 2023, 05-01, Volume: 76, Issue:5

    Topics: Airway Obstruction; Anesthesia; Apnea; Benzocaine; Child; Conscious Sedation; Endoscopy, Digestive S

2023
Comparison of upper airway obstruction during zolpidem-induced sleep and propofol-induced sleep in patients with obstructive sleep apnea: a pilot study.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2020, 05-15, Volume: 16, Issue:5

    Topics: Airway Obstruction; Endoscopy; Humans; Pilot Projects; Propofol; Sleep; Sleep Apnea, Obstructive; Zo

2020
Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2021, Volume: 164, Issue:2

    Topics: Adenoidectomy; Airway Obstruction; Child; Endoscopy; Female; Follow-Up Studies; Humans; Hypnotics an

2021
Propofol versus dexmedetomidine during drug-induced sleep endoscopy (DISE) for pediatric obstructive sleep apnea.
    Sleep & breathing = Schlaf & Atmung, 2021, Volume: 25, Issue:2

    Topics: Adolescent; Airway Obstruction; Child; Child, Preschool; Dexmedetomidine; Endoscopy; Female; Humans;

2021
Clinical observation of the combined use of propofol and etomidate in painless gastroscopy.
    Medicine, 2020, Nov-06, Volume: 99, Issue:45

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Arterial Pressure; Case-Control Studies; Drug T

2020
Does Sleep Endoscopy Staging Pattern Correlate With Outcome of Advanced Palatopharyngoplasty for Moderate to Severe Obstructive Sleep Apnea?
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2017, Oct-15, Volume: 13, Issue:10

    Topics: Adult; Airway Obstruction; Cohort Studies; Endoscopy; Female; Humans; Hypnotics and Sedatives; Male;

2017
Diagnosing Tongue Base Obstruction in Pierre Robin Sequence Infants: Sleep vs Awake Endoscopy.
    The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association, 2018, Volume: 55, Issue:5

    Topics: Airway Obstruction; Anesthetics, Inhalation; Anesthetics, Intravenous; Endoscopy; Female; Humans; In

2018
Acute presentation of a partially obstructing laryngeal tumour: adjuvant agents to gaseous induction of anaesthesia.
    BMJ case reports, 2018, Jul-12, Volume: 2018

    Topics: Airway Management; Airway Obstruction; Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous

2018
A retrospective comparison of propofol to dexmedetomidine for pediatric magnetic resonance imaging sedation in patients with mucopolysaccharidosis type II.
    Paediatric anaesthesia, 2018, Volume: 28, Issue:12

    Topics: Airway Obstruction; Anesthesia; Child; Child, Preschool; Deep Sedation; Dexmedetomidine; Hemodynamic

2018
Evaluation of drug-induced sleep endoscopy as a patient selection tool for implanted upper airway stimulation for obstructive sleep apnea.
    Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2013, May-15, Volume: 9, Issue:5

    Topics: Airway Obstruction; Electric Stimulation; Endoscopy; Female; Fiber Optic Technology; Humans; Hypnoti

2013
Airway management in a patient with bullous pemphigoid.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2013, Volume: 23, Issue:8

    Topics: Adult; Airway Management; Airway Obstruction; Anesthesia; Anesthetics, Intravenous; Female; Humans;

2013
Drug-induced sleep endoscopy in sleep-disordered breathing: report on 1,249 cases.
    The Laryngoscope, 2014, Volume: 124, Issue:3

    Topics: Adult; Age Factors; Airway Obstruction; Anthropometry; Body Mass Index; Clinical Competence; Cohort

2014
Awake versus drug-induced sleep endoscopy: evaluation of airway obstruction in obstructive sleep apnea/hypopnoea syndrome.
    The Laryngoscope, 2013, Volume: 123, Issue:9

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Cohort Studies; Endoscopy; Female; Humans; Lary

2013
European position paper on drug-induced sedation endoscopy (DISE).
    Sleep & breathing = Schlaf & Atmung, 2014, Volume: 18, Issue:3

    Topics: Airway Obstruction; Conscious Sedation; Drug Therapy, Combination; Endoscopy; Europe; Evidence-Based

2014
European position paper on drug-induced sedation endoscopy (DISE).
    Sleep & breathing = Schlaf & Atmung, 2014, Volume: 18, Issue:3

    Topics: Airway Obstruction; Conscious Sedation; Drug Therapy, Combination; Endoscopy; Europe; Evidence-Based

2014
European position paper on drug-induced sedation endoscopy (DISE).
    Sleep & breathing = Schlaf & Atmung, 2014, Volume: 18, Issue:3

    Topics: Airway Obstruction; Conscious Sedation; Drug Therapy, Combination; Endoscopy; Europe; Evidence-Based

2014
European position paper on drug-induced sedation endoscopy (DISE).
    Sleep & breathing = Schlaf & Atmung, 2014, Volume: 18, Issue:3

    Topics: Airway Obstruction; Conscious Sedation; Drug Therapy, Combination; Endoscopy; Europe; Evidence-Based

2014
The role of drug-induced sleep endoscopy in surgical planning for obstructive sleep apnea syndrome.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:8

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Endoscopy; Female; Humans; Male; Middle Aged; O

2015
The role of drug-induced sleep endoscopy in surgical planning for obstructive sleep apnea syndrome.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:8

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Endoscopy; Female; Humans; Male; Middle Aged; O

2015
The role of drug-induced sleep endoscopy in surgical planning for obstructive sleep apnea syndrome.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:8

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Endoscopy; Female; Humans; Male; Middle Aged; O

2015
The role of drug-induced sleep endoscopy in surgical planning for obstructive sleep apnea syndrome.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015, Volume: 272, Issue:8

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Endoscopy; Female; Humans; Male; Middle Aged; O

2015
[The impact of sleep endoscopy for obstructive sleep-disordered breathing in children and adolescents].
    Laryngo- rhino- otologie, 2014, Volume: 93, Issue:12

    Topics: Adolescent; Airway Obstruction; Anesthesia, Intravenous; Child; Child, Preschool; Diagnosis, Differe

2014
A retrospective study of anesthesia during rigid bronchoscopy for airway foreign body removal in children: propofol and sevoflurane with spontaneous ventilation.
    Paediatric anaesthesia, 2014, Volume: 24, Issue:10

    Topics: Airway Obstruction; Anesthesia; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intraveno

2014
Evaluation of acoustic characteristics of snoring sounds obtained during drug-induced sleep endoscopy.
    Sleep & breathing = Schlaf & Atmung, 2015, Volume: 19, Issue:3

    Topics: Airway Obstruction; Anesthesia, Intravenous; Diagnosis, Differential; Endoscopy; Humans; Male; Middl

2015
Effect of a neck collar on upper airway size in children sedated with propofol-midazolam combination during magnetic resonance imaging.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:4

    Topics: Airway Management; Airway Obstruction; Anatomy, Cross-Sectional; Body Weight; Child, Preschool; Cons

2015
Are the obstruction sites visualized on drug-induced sleep endoscopy reliable?
    Sleep & breathing = Schlaf & Atmung, 2015, Volume: 19, Issue:3

    Topics: Adult; Airway Obstruction; Anesthesia, Intravenous; Endoscopy; Female; Humans; Male; Middle Aged; Po

2015
[Is sleep endoscopy effective in snoring?].
    Laryngo- rhino- otologie, 2015, Volume: 94, Issue:4

    Topics: Airway Obstruction; Anesthesia, Intravenous; Endoscopy; Female; Humans; Male; Polysomnography; Propo

2015
Pharmacodynamic Estimate of Propofol-Induced Sedation and Airway Obstruction Effects in Obstructive Sleep Apnea-Hypopnea Syndrome.
    Yonsei medical journal, 2015, Volume: 56, Issue:5

    Topics: Adult; Aged; Airway Obstruction; Anesthesia; Anesthetics, Intravenous; Female; Humans; Hypnotics and

2015
Drug-induced sedation endoscopy versus clinical exploration for the diagnosis of severe upper airway obstruction in OSAHS patients.
    Sleep & breathing = Schlaf & Atmung, 2015, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Airway Obstruction; Conscious Sedation; Endoscopy; Female; Humans; Incidenc

2015
The Guedel airway: too large is too bad.
    Paediatric anaesthesia, 2015, Volume: 25, Issue:12

    Topics: Airway Management; Airway Obstruction; Anesthesia; Anesthetics, Intravenous; Craniosynostoses; Femal

2015
Complications of Deep Sedation for Individual Procedures (Lumbar Puncture Alone) Versus Combined Procedures (Lumbar Puncture and Bone Marrow Aspirate) in Pediatric Oncology Patients.
    Hospital pediatrics, 2016, Volume: 6, Issue:2

    Topics: Airway Obstruction; Biopsy, Needle; Bone Marrow Examination; Child; Child, Preschool; Deep Sedation;

2016
Drug-induced sleep endoscopy in children with Prader-Willi syndrome.
    Sleep & breathing = Schlaf & Atmung, 2016, Volume: 20, Issue:3

    Topics: Adolescent; Airway Obstruction; Anesthesia, Intravenous; Body Mass Index; Child; Child, Preschool; E

2016
Depth-dependent changes of obstruction patterns under increasing sedation during drug-induced sedation endoscopy: results of a German monocentric clinical trial.
    Sleep & breathing = Schlaf & Atmung, 2016, Volume: 20, Issue:3

    Topics: Adult; Airway Obstruction; Anesthesia, Intravenous; Dose-Response Relationship, Drug; Endoscopy; Fem

2016
Comparison of the combination of dexmedetomidine and ketamine to propofol or propofol/sevoflurane for drug-induced sleep endoscopy in children.
    Paediatric anaesthesia, 2016, Volume: 26, Issue:7

    Topics: Airway Obstruction; Analgesics; Anesthetics, Inhalation; Anesthetics, Intravenous; Causality; Child;

2016
A retrospective comparison of propofol alone to propofol in combination with dexmedetomidine for pediatric 3T MRI sedation.
    Paediatric anaesthesia, 2017, Volume: 27, Issue:1

    Topics: Airway Obstruction; Child, Preschool; Dexmedetomidine; Drug Therapy, Combination; Female; Humans; Hy

2017
Does dexmedetomidine cause less airway collapse than propofol when used for deep sedation?
    Journal of clinical anesthesia, 2016, Volume: 35

    Topics: Airway Obstruction; Anesthesia; Anesthetics, Inhalation; Child; Child, Preschool; Deep Sedation; Dex

2016
Drug-Induced Sleep Endoscopy Changes the Treatment Concept in Patients with Obstructive Sleep Apnoea.
    BioMed research international, 2016, Volume: 2016

    Topics: Adolescent; Adult; Airway Obstruction; Anesthetics, Intravenous; Anesthetics, Local; Continuous Posi

2016
Airway collapse or closure via the soft palate as mechanism of obstruction in sedated patients?
    Anesthesiology, 2010, Volume: 112, Issue:2

    Topics: Airway Obstruction; Conscious Sedation; Humans; Hypnotics and Sedatives; Monitoring, Intraoperative;

2010
[Anesthetic management in a tracheostomized patient with a bronchial foreign body].
    Revista espanola de anestesiologia y reanimacion, 2009, Volume: 56, Issue:9

    Topics: Airway Obstruction; Anesthesia, Intravenous; Bronchi; Bronchoscopes; Bronchoscopy; Carcinoma; Fiber

2009
[Transient decerebrate rigidity from hypoxemia during administration of propofol, midazolam-flumazenil, and remifentanil-naloxone].
    Revista espanola de anestesiologia y reanimacion, 2010, Volume: 57, Issue:2

    Topics: Airway Obstruction; Anesthetics, Intravenous; Bradycardia; Cardiotonic Agents; Cholangiopancreatogra

2010
The difficult airway in office-based anesthesia.
    Plastic and reconstructive surgery, 2010, Volume: 125, Issue:5

    Topics: Airway Obstruction; Ambulatory Surgical Procedures; Anesthesia, General; Anesthetics, Intravenous; H

2010
Opioid modeling of central respiratory drive must take upper airway obstruction into account.
    Anesthesiology, 2011, Volume: 114, Issue:1

    Topics: Airway Obstruction; Analgesics, Opioid; Anesthetics, Intravenous; Humans; Models, Biological; Piperi

2011
Takotsubo cardiomyopathy and the difficult airway.
    Journal of neurosurgical anesthesiology, 2011, Volume: 23, Issue:3

    Topics: Airway Obstruction; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intubation, Intratrach

2011
Nonresponders to pharyngeal surgery for obstructive sleep apnea: insights from drug-induced sleep endoscopy.
    The Laryngoscope, 2011, Volume: 121, Issue:6

    Topics: Adult; Aged; Airway Obstruction; Anesthetics, Intravenous; Conscious Sedation; Endoscopy; Female; Hu

2011
Does propofol induction in patients on olanzapine increase the susceptibility to dystonic reactions?
    Acta anaesthesiologica Scandinavica, 2011, Volume: 55, Issue:5

    Topics: Adult; Airway Obstruction; Anesthetics, Intravenous; Antipsychotic Agents; Benzodiazepines; Drug Int

2011
Drug-induced sleep endoscopy vs awake Müller's maneuver in the diagnosis of severe upper airway obstruction.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2013, Volume: 148, Issue:1

    Topics: Adult; Aged; Airway Obstruction; Anesthetics, Intravenous; Cohort Studies; Endoscopy; Female; Humans

2013
Modeling of the sedative and airway obstruction effects of propofol in patients with Parkinson disease undergoing stereotactic surgery.
    Anesthesiology, 2002, Volume: 97, Issue:6

    Topics: Adult; Aged; Airway Obstruction; Anesthetics, Intravenous; Conscious Sedation; Female; Humans; Male;

2002
Use of deep intravenous sedation with propofol and the laryngeal mask airway during transesophageal echocardiography.
    Journal of cardiothoracic and vascular anesthesia, 2003, Volume: 17, Issue:4

    Topics: Adult; Aged; Airway Obstruction; Anesthesiology; Anesthetics, Intravenous; Cardiology; Drug Therapy,

2003
Jet ventilation for laryngotracheal surgery in an ex-premature infant.
    Paediatric anaesthesia, 2005, Volume: 15, Issue:9

    Topics: Airway Obstruction; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; Anesth

2005
Collapsibility of the upper airway at different concentrations of propofol anesthesia.
    Anesthesiology, 2005, Volume: 103, Issue:3

    Topics: Adult; Airway Obstruction; Airway Resistance; Anesthetics, Intravenous; Child; Dose-Response Relatio

2005
Collapsibility of the upper airway at different concentrations of propofol anesthesia.
    Anesthesiology, 2005, Volume: 103, Issue:3

    Topics: Adult; Airway Obstruction; Airway Resistance; Anesthetics, Intravenous; Child; Dose-Response Relatio

2005
Collapsibility of the upper airway at different concentrations of propofol anesthesia.
    Anesthesiology, 2005, Volume: 103, Issue:3

    Topics: Adult; Airway Obstruction; Airway Resistance; Anesthetics, Intravenous; Child; Dose-Response Relatio

2005
Collapsibility of the upper airway at different concentrations of propofol anesthesia.
    Anesthesiology, 2005, Volume: 103, Issue:3

    Topics: Adult; Airway Obstruction; Airway Resistance; Anesthetics, Intravenous; Child; Dose-Response Relatio

2005
An unusual case of airway obstruction.
    European journal of anaesthesiology, 2006, Volume: 23, Issue:8

    Topics: Airway Obstruction; Alfentanil; Anesthetics, Inhalation; Humans; Intubation, Intratracheal; Male; Me

2006
The ex utero intrapartum treatment procedure: anesthetic considerations.
    Archives of gynecology and obstetrics, 2008, Volume: 277, Issue:1

    Topics: Adjuvants, Anesthesia; Adult; Airway Obstruction; Anesthesia, General; Anesthetics, Inhalation; Fema

2008
Scurvy: a disease of anesthetic interest? Scurvy and anesthesia.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:7

    Topics: Airway Obstruction; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Ascorbic

2008
Office-based ambulatory sedation--the use of the airway protector system during oral surgery: a prospective audit of the first 100 patients.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2008, Volume: 66, Issue:5

    Topics: Adolescent; Adult; Aged; Airway Obstruction; Ambulatory Surgical Procedures; Anesthesia, Dental; Ane

2008
Oral to nasal tube exchange under fibroscopic view: a new technique for nasal intubation in a predicted difficult airway.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:7

    Topics: Adjuvants, Anesthesia; Adolescent; Airway Obstruction; Anesthetics, Intravenous; Atropine; Cherubism

2008
Puncture of the laryngeal mask airway cuff.
    Anaesthesia, 1994, Volume: 49, Issue:10

    Topics: Airway Obstruction; Anesthesia, Intravenous; Fentanyl; Humans; Laryngeal Masks; Male; Obesity; Propo

1994
Effect of blood pressure changes on air flow dynamics in the upper airway of the decerebrate cat.
    Anesthesiology, 1996, Volume: 84, Issue:1

    Topics: Airway Obstruction; Airway Resistance; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; B

1996
Anaesthesia for a patient with a mediastinal mass presenting with acute stridor.
    Anaesthesia and intensive care, 1996, Volume: 24, Issue:5

    Topics: Aged; Airway Obstruction; Anesthesia, Intravenous; Anesthesia, Local; Anesthetics, Intravenous; Anes

1996
The difficult airway: propofol infusion as an alternative to gaseous induction.
    Anaesthesia and intensive care, 1997, Volume: 25, Issue:1

    Topics: Adult; Airway Obstruction; Anesthesia, Intravenous; Anesthetics, Intravenous; Hematoma; Humans; Intu

1997
Anesthetic management of laser surgery for central airway obstruction: a 12-year case series.
    Journal of cardiothoracic and vascular anesthesia, 1998, Volume: 12, Issue:2

    Topics: Airway Obstruction; Anesthesia, Intravenous; Anesthetics, Intravenous; Bronchial Diseases; Bronchosc

1998
Usefulness of continuous oxygen insufflation into trachea for management of upper airway obstruction during anesthesia.
    Anesthesiology, 2000, Volume: 93, Issue:1

    Topics: Adult; Aged; Airway Obstruction; Anesthesia, General; Anesthetics, Intravenous; Animals; Blood Gas A

2000
Additional clinical observations utilizing bispectral analysis.
    Anesthesia progress, 2000,Summer, Volume: 47, Issue:3

    Topics: Airway Obstruction; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthesia, General; Anesthe

2000
Airway management in spontaneously breathing anaesthetized children: comparison of the Laryngeal Mask Airway with the cuffed oropharyngeal airway.
    Paediatric anaesthesia, 2002, Volume: 12, Issue:5

    Topics: Adjuvants, Anesthesia; Adolescent; Airway Obstruction; Anesthesia; Anesthetics; Anesthetics, Inhalat

2002
Ultrasound assessment of the position of the tongue during induction of anaesthesia.
    British journal of anaesthesia, 1990, Volume: 65, Issue:6

    Topics: Adult; Airway Obstruction; Anesthesia, Intravenous; Female; Humans; Middle Aged; Movement; Propofol;

1990
[A ketalar-propofol combination in laser surgery for removal of obstruction from the upper respiratory tract].
    Minerva anestesiologica, 1990, Volume: 56, Issue:9

    Topics: Aged; Airway Obstruction; Anesthesia, General; Bronchial Neoplasms; Female; Humans; Ketamine; Laser

1990