propofol has been researched along with Agitation, Psychomotor in 86 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
Excerpt | Relevance | Reference |
---|---|---|
"The subjects were 83 premedicated children aged 1 to 6 years who underwent surgical procedures with propofol (group P, n=41) or with halothane (group H, n=42) anesthesia." | 9.14 | Emergence agitation in children after propofol versus halothane anesthesia. ( Baftiu, N; Hasani, A; Ozgen, S, 2009) |
" The authors compared the incidence and severity of emergence agitation in children who received a single dose of propofol at the end of strabismus surgery versus children who received saline." | 9.12 | A single dose of propofol at the end of surgery for the prevention of emergence agitation in children undergoing strabismus surgery during sevoflurane anesthesia. ( Aouad, MT; Bleik, JH; El-Khatib, MF; Kanazi, GE; Nasr, VG; Yazbeck-Karam, VG, 2007) |
"Emergence delirium and agitation (EAD) associated with sevoflurane general anesthesia are very commonly observed in young children." | 8.89 | Prevention of sevoflurane delirium and agitation with propofol. ( Messieha, Z, 2013) |
"Agitation is common in subarachnoid hemorrhage (SAH), and sedation with midazolam, propofol and dexmedetomidine is essential in agitation management." | 8.12 | Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study. ( A, JY; Ding, XS; Ge, WH; Li, YC; Liu, T; Na, SJ; Sun, RB; Wang, R, 2022) |
"The incidence of emergence agitation (EA) after sevoflurane anesthesia is high, especially in pediatric strabismus surgery." | 8.12 | Postoperative propofol bolus treatment did not affect recovery time in patients with emergence agitation after sevoflurane anesthesia in pediatric patients undergoing strabismus surgery: Prospective nonrandomized case-control study. ( Choi, YJ; Kim, JH; Shin, HW; Xu, GS; Yoon, SZ, 2022) |
"Accordingly, health care providers may consider using dexmedetomidine as adjunctive therapy for cases of severe serotonin syndrome that are refractory to standard treatment." | 7.80 | Dexmedetomidine in the treatment of serotonin syndrome. ( Charlton, NP; Rushton, WF, 2014) |
"Within the framework of this study the question arose whether the barbiturate methohexital could be associated with a lower incidence of delirium in comparison to midazolam or propofol in analgosedated and ventilated ICU patients." | 7.80 | [Methohexital for analgosedation of ventilated intensive care patients : prospective nonrandomized single center observational study on incidence of delirium]. ( Hopf, HB; Schütz, M; Vogt, A; Volz, D, 2014) |
" Although delirium caused by midazolam or propofol in different patients has been reported, the present case represents a delirium that developed from both drugs in the same patient, possibly because of the patient's smaller tolerance to midazolam and propofol." | 7.73 | Delirium during intravenous sedation with midazolam alone and with propofol in dental treatment. ( Inada, H; Jinno, S; Kohase, H; Mohri-Ikuzawa, Y; Takahashi, N; Umino, M, 2006) |
"Propofol is thought to act on gamma-aminobutyric acid receptors, which have some role in pain transmission in the spinal cord." | 7.72 | Intrathecal propofol has analgesic effects on inflammation-induced pain in rats. ( Hanaoka, K; Matsukawa, T; Nishiyama, T, 2004) |
"The subjects were 83 premedicated children aged 1 to 6 years who underwent surgical procedures with propofol (group P, n=41) or with halothane (group H, n=42) anesthesia." | 5.14 | Emergence agitation in children after propofol versus halothane anesthesia. ( Baftiu, N; Hasani, A; Ozgen, S, 2009) |
" The authors compared the incidence and severity of emergence agitation in children who received a single dose of propofol at the end of strabismus surgery versus children who received saline." | 5.12 | A single dose of propofol at the end of surgery for the prevention of emergence agitation in children undergoing strabismus surgery during sevoflurane anesthesia. ( Aouad, MT; Bleik, JH; El-Khatib, MF; Kanazi, GE; Nasr, VG; Yazbeck-Karam, VG, 2007) |
"Emergence delirium and agitation (EAD) associated with sevoflurane general anesthesia are very commonly observed in young children." | 4.89 | Prevention of sevoflurane delirium and agitation with propofol. ( Messieha, Z, 2013) |
"The incidence of emergence agitation (EA) after sevoflurane anesthesia is high, especially in pediatric strabismus surgery." | 4.12 | Postoperative propofol bolus treatment did not affect recovery time in patients with emergence agitation after sevoflurane anesthesia in pediatric patients undergoing strabismus surgery: Prospective nonrandomized case-control study. ( Choi, YJ; Kim, JH; Shin, HW; Xu, GS; Yoon, SZ, 2022) |
"Agitation is common in subarachnoid hemorrhage (SAH), and sedation with midazolam, propofol and dexmedetomidine is essential in agitation management." | 4.12 | Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study. ( A, JY; Ding, XS; Ge, WH; Li, YC; Liu, T; Na, SJ; Sun, RB; Wang, R, 2022) |
" This case report describes the successful use of propofol, an ultra-fast-acting anaesthetic agent commonly used for anaesthesia induction and maintenance to manage refractory agitated delirium in an acute inpatient palliative medicine setting." | 3.96 | Propofol for palliative sedation. ( Michael, NG; Sulistio, M; Wojnar, R, 2020) |
" Fentanyl (77%) and hydromorphone (48%) were the most common intravenous opioids used to manage pain." | 3.91 | Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation. ( Abrams, D; Agerstrand, C; Brodie, D; Dzierba, AL; Madahar, P; Muir, J, 2019) |
"Accordingly, health care providers may consider using dexmedetomidine as adjunctive therapy for cases of severe serotonin syndrome that are refractory to standard treatment." | 3.80 | Dexmedetomidine in the treatment of serotonin syndrome. ( Charlton, NP; Rushton, WF, 2014) |
"Within the framework of this study the question arose whether the barbiturate methohexital could be associated with a lower incidence of delirium in comparison to midazolam or propofol in analgosedated and ventilated ICU patients." | 3.80 | [Methohexital for analgosedation of ventilated intensive care patients : prospective nonrandomized single center observational study on incidence of delirium]. ( Hopf, HB; Schütz, M; Vogt, A; Volz, D, 2014) |
" Although delirium caused by midazolam or propofol in different patients has been reported, the present case represents a delirium that developed from both drugs in the same patient, possibly because of the patient's smaller tolerance to midazolam and propofol." | 3.73 | Delirium during intravenous sedation with midazolam alone and with propofol in dental treatment. ( Inada, H; Jinno, S; Kohase, H; Mohri-Ikuzawa, Y; Takahashi, N; Umino, M, 2006) |
"Propofol is thought to act on gamma-aminobutyric acid receptors, which have some role in pain transmission in the spinal cord." | 3.72 | Intrathecal propofol has analgesic effects on inflammation-induced pain in rats. ( Hanaoka, K; Matsukawa, T; Nishiyama, T, 2004) |
"Patients with superficial esophageal cancers who underwent esophageal endoscopic submucosal dissection at Yokohama City University Hospital were prospectively enrolled and were randomly assigned to the propofol and the propofol plus dexmedetomidine groups." | 3.01 | Efficacy of sedation with dexmedetomidine plus propofol during esophageal endoscopic submucosal dissection. ( Arimoto, J; Ashikari, K; Chiba, H; Fuyuki, A; Higurashi, T; Kanoshima, K; Matsuura, T; Misawa, N; Nakajima, A; Nonaka, T; Ohkubo, H; Takatsu, T; Yoshihara, T, 2021) |
"Modafinil 200 mg was administered to the treatment group patients 1 h before sedation/analgesia." | 2.75 | Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills. ( Boesjes, H; Galvin, E; Hol, J; Klein, J; Ubben, JF; Verbrugge, SJ, 2010) |
"Propofol was administered until the patients did not respond to a verbal command." | 2.74 | Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy. ( Bulut, M; Ganidagli, S; Koruk, S; Mizrak, A; Oner, U, 2009) |
"Propofol is an effective alternative to amobarbital in the Wada test, and may be used successfully in multiple repeated injections within the same test without significant residual sedation or significant adverse effects." | 2.74 | Intracarotid propofol testing: a comparative study with amobarbital. ( Baydoun, A; Comair, YG; El Yamen, S; Mikati, MA; Naasan, G; Tarabay, H, 2009) |
"Propofol doses were reduced by 20% (P = 0." | 2.74 | Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: a centre randomised, cross-over, open-label study in the Netherlands. ( Bakker, J; Foudraine, NA; Mulder, PG; Rozendaal, FW; Schoen, A; Snellen, FF; Spronk, PE; van Zanten, AR, 2009) |
"Midazolam and Propofol were used following a bolus-infusion sequence, both separately and in combination among themselves (MID\\PROP group), or with an opioid, Remifentanil (MID\\PROP\\REMI group)." | 2.72 | Neurosedation in dentistry of the disabled patient: the use of midazolam, propofol, and remifentanil. ( Barraco, G; Collini, S; Di Carlo, S; Gatto, R; Lejeune, L; Meloncelli, S; Pinto, G, 2006) |
" There were no statistically significant differences between the renal function groups in the incidence of adverse events, and no deaths were attributable to remifentanil use." | 2.71 | Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment. ( Albrecht, S; Bach, V; Bodenham, A; Bonde, J; Breen, D; Kessler, P; Shaikh, S; Wilmer, A, 2004) |
" It also reviews the comparative pharmacokinetics, adverse effects, and dosing of ketamine, propofol, and ketofol as agents for procedural sedation and analgesia." | 2.48 | Ketamine, propofol, and ketofol use for pediatric sedation. ( Alletag, MJ; Auerbach, MA; Baum, CR, 2012) |
"Conclusions A PTSD flashback may occur from ketamine sedation in patients with a past history of military experience and can be a manifestation of psychologic adverse effects of ketamine." | 1.51 | Post-traumatic stress disorder or emergence phenomena? A case of psychomotor agitation after procedural sedation and analgesia. ( Akbari, H; Bahreini, M; Jalali, A, 2019) |
"Intratracheal suctioning evoked significant changes in some physiological and behavioral parameters." | 1.38 | Assessment of pain in sedated and mechanically ventilated patients: an observational study. ( Hamers, JP; Hantikainen, V; Jakob, SM; Jeitziner, MM; Rohrer, O; Schwendimann, R, 2012) |
"57% of patients having complications (52 patients having 60 adverse events)." | 1.37 | Safety of intravenous sedation administered by the operating oral surgeon: the second 7 years of office practice. ( Rodgers, MS; Rodgers, SF, 2011) |
"Propofol was well tolerated with occasional, transient, and reversible drops in blood the pressure being the only adverse event noted." | 1.33 | Propofol for the management of emergence agitation after electroconvulsive therapy: review of a case series. ( Augoustides, JG; Datto, CJ; O'Reardon, JP; Takieddine, N, 2006) |
"Propofol therapy was begun in combination with valproic acid, fluoxetine, and risperidone to assist in the treatment of his severe agitation associated with the bipolar disease, inhibiting ventilatory weaning." | 1.32 | Propofol withdrawal syndrome in an adult patient with thermal injury. ( Ackerman, BH; Cawley, MJ; Guse, TM; Haith, LR; Laroia, A, 2003) |
"A propofol infusion was chosen for anaesthesia to achieve early discharge and to reduce the incidence of postoperative emesis." | 1.29 | Propofol for pulsed dye laser treatments in paediatric outpatients. ( Charest, J; Vischoff, D, 1994) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 7 (8.14) | 18.2507 |
2000's | 30 (34.88) | 29.6817 |
2010's | 40 (46.51) | 24.3611 |
2020's | 9 (10.47) | 2.80 |
Authors | Studies |
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Li, YC | 1 |
Wang, R | 1 |
A, JY | 1 |
Sun, RB | 1 |
Na, SJ | 1 |
Liu, T | 1 |
Ding, XS | 1 |
Ge, WH | 1 |
Xu, GS | 1 |
Yoon, SZ | 1 |
Choi, YJ | 1 |
Shin, HW | 1 |
Kim, JH | 2 |
Sumie, M | 1 |
Yang, A | 1 |
Hayes, J | 1 |
Yamaura, K | 1 |
Aoyama, K | 1 |
Beilstein, CM | 1 |
Meyer, A | 1 |
Lehmann, LE | 1 |
Wuethrich, PY | 1 |
Sulistio, M | 1 |
Wojnar, R | 1 |
Michael, NG | 1 |
Patel, C | 1 |
Kleinig, P | 1 |
Bakker, M | 1 |
Tait, P | 1 |
Jalali, A | 1 |
Akbari, H | 1 |
Bahreini, M | 1 |
Tang, W | 1 |
He, D | 1 |
Liu, Y | 1 |
Yang, L | 1 |
Ton, H | 1 |
Zhao, R | 1 |
Geron, E | 1 |
Li, M | 2 |
Dong, Y | 1 |
Zhang, Y | 1 |
Yu, B | 1 |
Yang, G | 1 |
Xie, Z | 1 |
Ashikari, K | 1 |
Nonaka, T | 1 |
Higurashi, T | 1 |
Takatsu, T | 1 |
Yoshihara, T | 1 |
Misawa, N | 1 |
Arimoto, J | 1 |
Kanoshima, K | 1 |
Matsuura, T | 1 |
Fuyuki, A | 1 |
Ohkubo, H | 1 |
Chiba, H | 1 |
Nakajima, A | 1 |
Azizkhani, R | 1 |
Kouhestani, S | 1 |
Heydari, F | 1 |
Majidinejad, S | 1 |
Shin, HJ | 1 |
Koo, BW | 1 |
Bang, SU | 1 |
Hwang, JW | 1 |
DO, SH | 1 |
Na, HS | 1 |
Zhong, Q | 1 |
Qu, X | 1 |
Xu, C | 1 |
Dzierba, AL | 1 |
Abrams, D | 1 |
Madahar, P | 1 |
Muir, J | 1 |
Agerstrand, C | 1 |
Brodie, D | 1 |
Tan, D | 1 |
Xia, H | 1 |
Sun, S | 1 |
Wang, F | 1 |
Cohen, MB | 1 |
Stewart, JT | 1 |
Jarman, A | 1 |
Duke, G | 1 |
Reade, M | 1 |
Casamento, A | 1 |
Messieha, Z | 1 |
Tzabazis, A | 1 |
Schmitt, HJ | 2 |
Ihmsen, H | 1 |
Schmidtlein, M | 1 |
Zimmermann, R | 1 |
Wielopolski, J | 1 |
Münster, T | 1 |
Kanaya, A | 1 |
Kuratani, N | 1 |
Satoh, D | 1 |
Kurosawa, S | 1 |
Sharma, A | 1 |
Singh, PM | 1 |
Trikha, A | 2 |
Rewari, V | 2 |
Chen, L | 1 |
Yu, L | 1 |
Fan, Y | 1 |
Manyande, A | 1 |
Liu, GY | 1 |
Chen, ZQ | 1 |
Zhang, ZW | 1 |
Volz, D | 1 |
Vogt, A | 1 |
Schütz, M | 1 |
Hopf, HB | 1 |
Tzabazis, AZ | 1 |
Muenster, T | 1 |
Benedict, N | 1 |
Felbinger, M | 1 |
Ridenour, T | 1 |
Anthes, A | 1 |
Altawalbeh, S | 1 |
Kane-Gill, S | 1 |
Almenrader, N | 1 |
Galante, D | 1 |
Engelhardt, T | 1 |
Swartz, CM | 2 |
Rushton, WF | 1 |
Charlton, NP | 1 |
Costi, D | 1 |
Ellwood, J | 1 |
Wallace, A | 1 |
Ahmed, S | 1 |
Waring, L | 1 |
Cyna, A | 1 |
Carrió, M | 1 |
Carmona, P | 1 |
van Hoff, SL | 1 |
O'Neill, ES | 1 |
Cohen, LC | 1 |
Collins, BA | 1 |
Jiang, S | 1 |
Liu, J | 1 |
Ji, W | 1 |
Liang, J | 1 |
Riddell, J | 1 |
Tran, A | 1 |
Bengiamin, R | 1 |
Hendey, GW | 1 |
Armenian, P | 1 |
Rozendaal, FW | 1 |
Spronk, PE | 1 |
Snellen, FF | 1 |
Schoen, A | 1 |
van Zanten, AR | 1 |
Foudraine, NA | 1 |
Mulder, PG | 1 |
Bakker, J | 1 |
Ting, JY | 1 |
Chatterjee, R | 1 |
Mikati, MA | 1 |
Naasan, G | 1 |
Tarabay, H | 1 |
El Yamen, S | 1 |
Baydoun, A | 1 |
Comair, YG | 1 |
Mizrak, A | 1 |
Koruk, S | 1 |
Ganidagli, S | 1 |
Bulut, M | 1 |
Oner, U | 1 |
Hasani, A | 1 |
Ozgen, S | 1 |
Baftiu, N | 1 |
Bryan, YF | 1 |
Hoke, LK | 1 |
Taghon, TA | 1 |
Nick, TG | 1 |
Wang, Y | 2 |
Kennedy, SM | 1 |
Furstein, JS | 1 |
Kurth, CD | 1 |
Galvin, E | 1 |
Boesjes, H | 1 |
Hol, J | 1 |
Ubben, JF | 1 |
Klein, J | 1 |
Verbrugge, SJ | 1 |
Almgren, M | 1 |
Lundmark, M | 1 |
Samuelson, K | 1 |
Karamchandani, K | 1 |
Batra, RK | 1 |
Dong, YX | 1 |
Meng, LX | 1 |
Zhang, JJ | 1 |
Zhao, GY | 1 |
Ma, CH | 1 |
Chen, J | 1 |
Li, W | 1 |
Hu, X | 1 |
Wang, D | 1 |
Apan, A | 1 |
Aykaç, E | 1 |
Kazkayasi, M | 1 |
Doganci, N | 1 |
Tahran, FD | 1 |
Seo, IS | 1 |
Seong, CR | 1 |
Jung, G | 1 |
Park, SJ | 1 |
Kim, SY | 1 |
Kim, MM | 1 |
Eich, C | 1 |
Verhagen-Henning, S | 1 |
Roessler, M | 1 |
Cremer, F | 1 |
Cremer, S | 1 |
Strack, M | 1 |
Russo, SG | 1 |
Key, KL | 1 |
Rich, C | 1 |
DeCristofaro, C | 1 |
Collins, S | 1 |
Rodgers, SF | 1 |
Rodgers, MS | 1 |
Anghelescu, DL | 1 |
Rakes, LC | 1 |
Shearer, JR | 1 |
Bikhazi, GB | 1 |
Jeitziner, MM | 1 |
Schwendimann, R | 1 |
Hamers, JP | 1 |
Rohrer, O | 1 |
Hantikainen, V | 1 |
Jakob, SM | 1 |
Gallegos, J | 1 |
Vaidya, P | 1 |
D'Agati, D | 1 |
Jayaram, G | 1 |
Nguyen, T | 1 |
Tripathi, A | 1 |
Trivedi, JK | 1 |
Reti, IM | 1 |
Tabrizi, R | 1 |
Eftekharian, HR | 1 |
Langner, NJ | 1 |
Ozkan, BT | 1 |
Alletag, MJ | 1 |
Auerbach, MA | 1 |
Baum, CR | 1 |
Cohen, IT | 2 |
Drewsen, S | 1 |
Hannallah, RS | 2 |
Augoustides, JG | 2 |
Greenblatt, E | 1 |
Abbas, MA | 1 |
O'Reardon, JP | 2 |
Datto, CJ | 2 |
Finkel, JC | 1 |
Hummer, KA | 1 |
Patel, KM | 1 |
Saito, M | 1 |
Terao, Y | 1 |
Fukusaki, M | 1 |
Makita, T | 1 |
Shibata, O | 1 |
Sumikawa, K | 1 |
Chiba, S | 1 |
Shima, T | 1 |
Murakami, N | 1 |
Kato, M | 1 |
Cawley, MJ | 1 |
Guse, TM | 1 |
Laroia, A | 1 |
Haith, LR | 1 |
Ackerman, BH | 1 |
Stewart, PC | 1 |
Cunnington, P | 1 |
Martin, R | 1 |
Siegel, MD | 1 |
Breen, D | 1 |
Wilmer, A | 1 |
Bodenham, A | 1 |
Bach, V | 1 |
Bonde, J | 1 |
Kessler, P | 1 |
Albrecht, S | 1 |
Shaikh, S | 1 |
Nishiyama, T | 1 |
Matsukawa, T | 1 |
Hanaoka, K | 1 |
Huang, SJ | 1 |
Shieh, JS | 1 |
Fu, M | 1 |
Kao, MC | 1 |
Collini, S | 1 |
Pinto, G | 1 |
Lejeune, L | 1 |
Di Carlo, S | 1 |
Meloncelli, S | 1 |
Barraco, G | 1 |
Gatto, R | 1 |
Auerswald, K | 1 |
Behrends, K | 1 |
Burkhardt, U | 1 |
Olthoff, D | 1 |
Takieddine, N | 1 |
Aoki, M | 1 |
Nishimura, Y | 1 |
Baba, H | 1 |
Okawa, Y | 1 |
Mohri-Ikuzawa, Y | 1 |
Inada, H | 1 |
Takahashi, N | 1 |
Kohase, H | 1 |
Jinno, S | 1 |
Umino, M | 1 |
Weitz, G | 1 |
Homann, N | 1 |
von Jagow, DC | 1 |
Wellhöner, P | 1 |
Sauer, A | 1 |
Ludwig, D | 1 |
Aouad, MT | 2 |
Yazbeck-Karam, VG | 1 |
Nasr, VG | 1 |
El-Khatib, MF | 1 |
Kanazi, GE | 2 |
Bleik, JH | 1 |
Abu-Shahwan, I | 1 |
Moussa, AR | 1 |
Dagher, CM | 1 |
Muwakkit, SA | 1 |
Jabbour-Khoury, SI | 1 |
Zbeidy, RA | 1 |
Abboud, MR | 1 |
Fowler, SB | 1 |
Hertzog, J | 1 |
Wagner, BK | 1 |
Vischoff, D | 1 |
Charest, J | 1 |
Moyle, J | 1 |
Manninen, PH | 1 |
Chan, AS | 1 |
Papworth, D | 1 |
Covington, H | 1 |
Holger, JS | 1 |
Hale, DB | 1 |
Harris, CR | 1 |
Solberg, C | 1 |
Benfante, F | 1 |
Picard, V | 1 |
Dumont, L | 1 |
Pellegrini, M | 1 |
Uezono, S | 1 |
Goto, T | 1 |
Terui, K | 1 |
Ichinose, F | 1 |
Ishguro, Y | 1 |
Nakata, Y | 1 |
Morita, S | 1 |
Gozal, D | 1 |
Gozal, Y | 1 |
Collins, PD | 1 |
Poole, K | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Clinical Study on the Effects of Propofol for Treatment on Emergence Agitation After Sevoflurane Anesthesia in Pediatric Strabismus Surgery[NCT02738814] | Phase 4 | 100 participants (Anticipated) | Interventional | 2016-04-30 | Enrolling by invitation | ||
Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954] | 54 participants (Actual) | Interventional | 2018-05-31 | Completed | |||
Effect of Different Administrations of Propofol on Emergence Agitation in Preschool Children Undergoing Ambulatory Surgery[NCT05420402] | 168 participants (Anticipated) | Interventional | 2022-08-01 | Active, not recruiting | |||
A Randomized, Double Blind, Placebo Controlled Evaluation of Modafinil vs Placebo for the Treatment of General Anesthesia Related Delayed Emergence in Patients With the Diagnosis of Obstructive Sleep Apnea[NCT02494102] | Phase 4 | 105 participants (Actual) | Interventional | 2016-02-29 | Terminated | ||
Delirium Screening 3 Methods Study (DELIS-3). Agreement Between CAM-ICU, CAM-ICU-7 and ICDSC in a Danish Population of ICU Patients and Nurses' Perception of the Clinical Relevance of Delirium Screening[NCT04551508] | 1,126 participants (Actual) | Observational | 2020-09-09 | Completed | |||
[NCT01506622] | 222 participants (Actual) | Interventional | 2011-01-31 | Completed | |||
Efficacy and Safety of Esketamine or Sevoflurane Add to Dexmedetomidine-based Sedation for Ophthalmology Procedure in Children[NCT05321160] | 116 participants (Actual) | Interventional | 2021-03-10 | Completed | |||
Comparison of Efficacy of Premedication Between Dexmedetomidine and Midazolam Intranasal for the Prevention of Emergence Delirium in Children Undergoing Ophthalmic Surgery[NCT04263844] | Phase 4 | 66 participants (Actual) | Interventional | 2019-01-10 | Completed | ||
Smart Pain Assesment Tool Based on Internet of Things[NCT03061240] | 58 participants (Actual) | Interventional | 2017-11-20 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Length of time of above compared between groups (NCT02494102)
Timeframe: 24 hours
Intervention | minutes (Mean) |
---|---|
Placebo | 53.5 |
Modafinil | 61.0 |
Postanesthesia quality recovery scale (PQRS). Component and aggregate scoring on the scale. Measures physiology, nociceptive, emotional activities of daily living cognitive and overall patient perspective. The scale is dimensionless and the aggregate of all individually tested dimensions is scaled from 17-65. A higher value implies improved postanesthesia recovery. Mean difference was assessed in each patient and aggregated thus patients with no difference between pre- and post-operative scores were zeroed (received a zero score if the difference was zero). A negative value was associated with worse outcome. (NCT02494102)
Timeframe: baseline and 6 hours after surgery
Intervention | units on a scale (Mean) |
---|---|
Placebo | -5.67 |
Modafinil | -8.91 |
13 reviews available for propofol and Agitation, Psychomotor
Article | Year |
---|---|
Palliative sedation: A safety net for the relief of refractory and intolerable symptoms at the end of life.
Topics: Aged; Analgesics; Conscious Sedation; Dehydration; Dyspnea; Humans; Hydromorphone; Hypnotics and Sed | 2019 |
Effect of Dexmedetomidine in children undergoing general anaesthesia with sevoflurane: a meta-analysis and systematic review.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; C | 2020 |
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theo | 2019 |
Prevention of sevoflurane delirium and agitation with propofol.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Consciousness Monitors; Delirium; Humans; Methyl | 2013 |
Lower incidence of emergence agitation in children after propofol anesthesia compared with sevoflurane: a meta-analysis of randomized controlled trials.
Topics: Adolescent; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, I | 2014 |
Does a prophylactic dose of propofol reduce emergence agitation in children receiving anesthesia? A systematic review and meta-analysis.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Humans; Hy | 2015 |
Does a prophylactic dose of propofol reduce emergence agitation in children receiving anesthesia? A systematic review and meta-analysis.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Humans; Hy | 2015 |
Does a prophylactic dose of propofol reduce emergence agitation in children receiving anesthesia? A systematic review and meta-analysis.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Humans; Hy | 2015 |
Does a prophylactic dose of propofol reduce emergence agitation in children receiving anesthesia? A systematic review and meta-analysis.
Topics: Adolescent; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Humans; Hy | 2015 |
The efficacy of propofol on emergence agitation--a meta-analysis of randomized controlled trials.
Topics: Desflurane; Humans; Isoflurane; Length of Stay; Methyl Ethers; Propofol; Psychomotor Agitation; Rand | 2015 |
Use of propofol and emergence agitation in children: a literature review.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation | 2010 |
Use of propofol and emergence agitation in children: a literature review.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation | 2010 |
Use of propofol and emergence agitation in children: a literature review.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation | 2010 |
Use of propofol and emergence agitation in children: a literature review.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation | 2010 |
Decreasing adverse outcomes of unmodified electroconvulsive therapy: suggestions and possibilities.
Topics: Anesthesia; Anesthetics, Intravenous; Anxiety; Benzodiazepines; Confusion; Depressive Disorder; Deve | 2012 |
Ketamine, propofol, and ketofol use for pediatric sedation.
Topics: Adolescent; Amnesia; Analgesia; Analgesics, Non-Narcotic; Anesthetics, Dissociative; Antiemetics; An | 2012 |
Management of agitation in the intensive care unit.
Topics: Benzodiazepines; Clinical Protocols; Critical Care; Critical Illness; Delirium; Humans; Hypnotics an | 2003 |
Pharmacological interventions for agitation in head-injured patients in the acute care setting.
Topics: Adult; Brain Injuries; Critical Care; Dose-Response Relationship, Drug; Drug Administration Schedule | 1995 |
Use of propofol for sedation in the ICU.
Topics: Anxiety; Critical Care; Drug Monitoring; Humans; Hypnotics and Sedatives; Intensive Care Units; Nurs | 1998 |
33 trials available for propofol and Agitation, Psychomotor
Article | Year |
---|---|
Efficacy of sedation with dexmedetomidine plus propofol during esophageal endoscopic submucosal dissection.
Topics: Conscious Sedation; Dexmedetomidine; Endoscopic Mucosal Resection; Esophageal Neoplasms; Humans; Hyp | 2021 |
A comparative study of dexmedetomidine and propofol to prevent recovery agitation in adults undergoing procedural sedation with ketamine: A randomized double-blind clinical trial.
Topics: Adult; Anesthetics, Dissociative; Conscious Sedation; Dexmedetomidine; Double-Blind Method; Emergenc | 2021 |
Effect of preoperative visiting operation room on emergence agitation in preschool children under sevoflurane anesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Child; Child, Preschool; E | 2018 |
Entropy correlates with Richmond Agitation Sedation Scale in mechanically ventilated critically ill patients.
Topics: Adolescent; Adult; Aged; Anesthetics, Intravenous; Conscious Sedation; Consciousness; Consciousness | 2014 |
A comparison between total intravenous anaesthesia using propofol plus remifentanil and volatile induction/ maintenance of anaesthesia using sevoflurane in children undergoing flexible fibreoptic bronchoscopy.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Biomarkers; Blood Glu | 2013 |
Comparative study of emergence agitation between isoflurane and propofol anesthesia in adults after closed reduction of distal radius fracture.
Topics: Adult; Aged; Anesthesia; Demography; Female; Humans; Isoflurane; Male; Middle Aged; Perioperative Ca | 2014 |
Transition to propofol after sevoflurane anesthesia to prevent emergence agitation: a randomized controlled trial.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Causality; Child; Chi | 2015 |
Remifentanil-propofol analgo-sedation shortens duration of ventilation and length of ICU stay compared to a conventional regimen: a centre randomised, cross-over, open-label study in the Netherlands.
Topics: Cross-Over Studies; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Netherlands; Piperid | 2009 |
Intracarotid propofol testing: a comparative study with amobarbital.
Topics: Adult; Aggression; Amobarbital; Anesthesia, Intravenous; Anesthetics, Intravenous; Carotid Arteries; | 2009 |
Premedication with dexmedetomidine and midazolam attenuates agitation after electroconvulsive therapy.
Topics: Adult; Anesthesia; Bipolar Disorder; Blood Pressure; Depressive Disorder, Major; Dexmedetomidine; El | 2009 |
Emergence agitation in children after propofol versus halothane anesthesia.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; De | 2009 |
A randomized trial comparing sevoflurane and propofol in children undergoing MRI scans.
Topics: Algorithms; Anesthesia, General; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhal | 2009 |
Modafinil reduces patient-reported tiredness after sedation/analgesia but does not improve patient psychomotor skills.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Anesthesia Recovery Period; Anesthetics, Inha | 2010 |
The effect of remifentanil on the incidence of agitation on emergence from sevoflurane anaesthesia in children undergoing adenotonsillectomy.
Topics: Adenoids; Analgesics, Opioid; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intr | 2010 |
Emergence agitation after cataract surgery in children: a comparison of midazolam, propofol and ketamine.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Dissociative; Anesthetics, Inhalation; | 2010 |
Magnesium sulphate infusion is not effective on discomfort or emergence phenomenon in paediatric adenoidectomy/tonsillectomy.
Topics: Adenoidectomy; Adolescent; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Combined; A | 2010 |
The effect of sub-Tenon lidocaine injection on emergence agitation after general anaesthesia in paediatric strabismus surgery.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Combined; Anesthetics, Inhalation; Ane | 2011 |
Propofol or midazolam do not reduce the incidence of emergence agitation associated with desflurane anaesthesia in children undergoing adenotonsillectomy.
Topics: Adenoidectomy; Anesthesia Recovery Period; Anesthetics, Inhalation; Child; Child, Preschool; Desflur | 2002 |
Rapid emergence does not explain agitation following sevoflurane anaesthesia in infants and children: a comparison with propofol.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2003 |
Sequential use of midazolam and propofol for long-term sedation in postoperative mechanically ventilated patients.
Topics: Analgesics, Opioid; Buprenorphine; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Male | 2003 |
[Effect of propofol on sevoflurane agitation in children].
Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; A | 2003 |
Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Conscious Sedation; Drug Therapy, Combination; Female; | 2004 |
Fuzzy logic control for intracranial pressure via continuous propofol sedation in a neurosurgical intensive care unit.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Biomedical Engineering; Brain Injuries; Critical Care; F | 2006 |
Neurosedation in dentistry of the disabled patient: the use of midazolam, propofol, and remifentanil.
Topics: Adult; Conscious Sedation; Dental Anxiety; Dental Implantation; Disabled Persons; Drug Synergism; Dr | 2006 |
[Propofol for paediatric patients in ear, nose and throat surgery. Practicability, quality and cost-effectiveness of different anaesthesia procedures for adenoidectomy in infants].
Topics: Adenoidectomy; Alfentanil; Anesthesia, Inhalation; Anesthesia, Intravenous; Anesthetics, Inhalation; | 2006 |
Premedication with orally administered lorazepam in adults undergoing ERCP: a randomized double-blind study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograd | 2007 |
A single dose of propofol at the end of surgery for the prevention of emergence agitation in children undergoing strabismus surgery during sevoflurane anesthesia.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Prescho | 2007 |
Effect of propofol on emergence behavior in children after sevoflurane general anesthesia.
Topics: Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; Anesthetics, Intravenous; | 2008 |
Addition of ketamine to propofol for initiation of procedural anesthesia in children reduces propofol consumption and preserves hemodynamic stability.
Topics: Adolescent; Analgesics; Anesthesia; Anesthetics, Intravenous; Biopsy, Needle; Blood Pressure; Child; | 2008 |
Conscious sedation for interventional neuroradiology: a comparison of midazolam and propofol infusion.
Topics: Adult; Anesthetics, Intravenous; Anxiety; Attitude of Health Personnel; Cerebrovascular Disorders; C | 1997 |
Sedation of intoxicated, agitated patients requiring CT to evaluate head injury.
Topics: Adolescent; Adult; Aged; Alcoholic Intoxication; Craniocerebral Trauma; Female; Humans; Hypnotics an | 1999 |
Quality of recovery in children: sevoflurane versus propofol.
Topics: Anesthetics; Child; Child, Preschool; Female; Humans; Male; Methyl Ethers; Propofol; Psychomotor Agi | 2000 |
Emergence agitation after sevoflurane versus propofol in pediatric patients.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Child, Preschool; Cro | 2000 |
40 other studies available for propofol and Agitation, Psychomotor
Article | Year |
---|---|
Cerebrospinal fluid metabolic profiling reveals divergent modulation of pentose phosphate pathway by midazolam, propofol and dexmedetomidine in patients with subarachnoid hemorrhage: a cohort study.
Topics: Aged; Cohort Studies; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Midazolam; Mid | 2022 |
Postoperative propofol bolus treatment did not affect recovery time in patients with emergence agitation after sevoflurane anesthesia in pediatric patients undergoing strabismus surgery: Prospective nonrandomized case-control study.
Topics: Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Case-Control Studies; Child; Emerge | 2022 |
How to mitigate confounding factors in observational studies.
Topics: Anesthetics, Intravenous; Humans; Propofol; Psychomotor Agitation | 2023 |
Comments on "Postanesthesia Recovery Unit Optimization for Patients With Postictal Agitation Secondary to Electroconvulsive Therapy" by Arora et al.
Topics: Depressive Disorder, Major; Electroconvulsive Therapy; Humans; Propofol; Psychomotor Agitation | 2023 |
Propofol for palliative sedation.
Topics: Delirium; Female; Humans; Hypnotics and Sedatives; Middle Aged; Pain; Palliative Care; Propofol; Psy | 2020 |
Post-traumatic stress disorder or emergence phenomena? A case of psychomotor agitation after procedural sedation and analgesia.
Topics: Analgesia; Analgesics; Conscious Sedation; Emergency Service, Hospital; Humans; Injections, Intramus | 2019 |
Sevoflurane induces neuronal activation and behavioral hyperactivity in young mice.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Behavior, Animal; Disease Models, Animal; | 2020 |
Intraoperative dexmedetomidine sedation reduces the postoperative agitated behavior in elderly patients undergoing orthopedic surgery compared to the propofol sedation.
Topics: Aged; Deep Sedation; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Incidence; Intraopera | 2017 |
Current practice and perceptions regarding pain, agitation and delirium management in patients receiving venovenous extracorporeal membrane oxygenation.
Topics: Adult; Analgesics, Opioid; Anesthesia; Anesthetics, Intravenous; Attitude of Health Personnel; Benzo | 2019 |
Treatment of post-electroconvulsive therapy agitation with dexmedetomidine.
Topics: Aged; Depressive Disorder, Major; Dexmedetomidine; Electroconvulsive Therapy; Humans; Hypnotics and | 2013 |
The association between sedation practices and duration of mechanical ventilation in intensive care.
Topics: Adult; Aged; Analgesics, Opioid; Conscious Sedation; Critical Care; Female; Humans; Hypnotics and Se | 2013 |
Postictal agitation after electroconvulsive therapy: incidence, severity, and propofol as a treatment option.
Topics: Adult; Age Factors; Anesthesia; Anesthesia Recovery Period; Depressive Disorder, Major; Electroconvu | 2013 |
[Methohexital for analgosedation of ventilated intensive care patients : prospective nonrandomized single center observational study on incidence of delirium].
Topics: Aged; Analgesics, Opioid; Anesthetics, Intravenous; Checklist; Cohort Studies; Critical Care; Deliri | 2014 |
Postictal agitation after electroconvulsive therapy.
Topics: Electroconvulsive Therapy; Female; Humans; Hypnotics and Sedatives; Male; Propofol; Psychomotor Agit | 2014 |
Correlation of patient-reported outcomes of sedation and sedation assessment scores in critically ill patients.
Topics: Adult; Conscious Sedation; Critical Illness; Dexmedetomidine; Female; Humans; Hypnotics and Sedative | 2014 |
Emergence agitation: is there a European consensus?
Topics: Analgesics, Opioid; Anesthesia Recovery Period; Child; Consensus; Delirium; Europe; Humans; Hypnotic | 2014 |
Postictal agitation syndrome or anxiety symptoms.
Topics: Electroconvulsive Therapy; Female; Humans; Hypnotics and Sedatives; Male; Propofol; Psychomotor Agit | 2014 |
Dexmedetomidine in the treatment of serotonin syndrome.
Topics: Adolescent; Adrenergic alpha-Agonists; Benzodiazepines; Dexmedetomidine; Female; Humans; Hypnotics a | 2014 |
[Ventricular fibrillation and cardiorespiratory arrest during dexmedetomidine administration].
Topics: Adrenergic alpha-2 Receptor Agonists; Advanced Cardiac Life Support; Aged; Airway Extubation; Aortic | 2015 |
Ketamine as a first-line treatment for severely agitated emergency department patients.
Topics: Adolescent; Adult; Anesthetics, Dissociative; California; Conscious Sedation; Dose-Response Relation | 2017 |
Using propofol as salvage therapy to contain severe drug-induced agitation in the Emergency Department: a case report.
Topics: Adult; Emergency Service, Hospital; Female; Humans; Hypnotics and Sedatives; Illicit Drugs; Infusion | 2008 |
The Richmond Agitation-Sedation Scale: translation and reliability testing in a Swedish intensive care unit.
Topics: Aged; APACHE; Awareness; Conscious Sedation; Female; Humans; Hypnotics and Sedatives; Intensive Care | 2010 |
Bispectral index correlates well with Richmond agitation sedation scale in mechanically ventilated critically ill patients.
Topics: Adolescent; Adult; Blood Gas Analysis; Conscious Sedation; Consciousness Monitors; Critical Care; Cr | 2010 |
Low-dose S-ketamine added to propofol anesthesia for magnetic resonance imaging in children is safe and ensures faster recovery--a prospective evaluation.
Topics: Anesthesia, Intravenous; Anesthetics, Dissociative; Anesthetics, Intravenous; Child; Child, Preschoo | 2011 |
Safety of intravenous sedation administered by the operating oral surgeon: the second 7 years of office practice.
Topics: Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthetics, Intravenous; Conscious | 2011 |
Prevention of emergence agitation in seven children receiving low-dose ketamine and propofol total intravenous anesthesia.
Topics: Anesthetics, Dissociative; Anesthetics, Intravenous; Child, Preschool; Drug Interactions; Humans; In | 2011 |
Assessment of pain in sedated and mechanically ventilated patients: an observational study.
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Analysis of Variance; Behavior; Cons | 2012 |
Comparison of the effect of 2 hypotensive anesthetic techniques on early recovery complications after orthognathic surgery.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Chi-Square Distributi | 2012 |
Clinical approach to agitation after electroconvulsive therapy: a case report and literature review.
Topics: Anesthesia Recovery Period; Bipolar Disorder; Drug Therapy, Combination; Electroconvulsive Therapy; | 2002 |
Propofol withdrawal syndrome in an adult patient with thermal injury.
Topics: Bipolar Disorder; Burns; Ethanol; Fatal Outcome; Humans; Hypnotics and Sedatives; Male; Middle Aged; | 2003 |
Comment on Cohen et al.
Topics: Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics, Intravenous; Child; Child, Prescho | 2003 |
Intrathecal propofol has analgesic effects on inflammation-induced pain in rats.
Topics: Analgesics; Animals; Disease Models, Animal; Formaldehyde; Hot Temperature; Inflammation; Injections | 2004 |
Aspiration and postictal agitation after electroconvulsive therapy with propofol but no succinylcholine or atropinic agent.
Topics: Adjuvants, Anesthesia; Anesthetics, Intravenous; Atropine; Electroconvulsive Therapy; Humans; Neurom | 2005 |
Propofol for the management of emergence agitation after electroconvulsive therapy: review of a case series.
Topics: Adult; Aged; Aged, 80 and over; Bipolar Disorder; Depressive Disorder, Major; Electroconvulsive Ther | 2006 |
[Effects of dexmedetomidine hydrochloride on postoperative sedation in cardiovascular surgery].
Topics: Aged; Anxiety; Cardiovascular Surgical Procedures; Dexmedetomidine; Female; Humans; Hypnotics and Se | 2006 |
Delirium during intravenous sedation with midazolam alone and with propofol in dental treatment.
Topics: Alveolar Ridge Augmentation; Anesthesia, Dental; Anesthetics, Combined; Anesthetics, Intravenous; Co | 2006 |
Propofol for pulsed dye laser treatments in paediatric outpatients.
Topics: Acetaminophen; Anesthesia Recovery Period; Anesthesia, Intravenous; Child; Child, Preschool; Facial | 1994 |
The use of propofol in palliative medicine.
Topics: Aged; Anesthetics, Intravenous; Delirium; Humans; Hypnotics and Sedatives; Male; Neoplasms; Palliati | 1995 |
An unusual cause of failed sedation.
Topics: Adolescent; Adolescent Behavior; Anesthesia, Intravenous; Anesthetics, Intravenous; Animals; Cardiac | 2000 |
Terminal restlessness--its management and the role of midazolam.
Topics: Humans; Midazolam; Propofol; Psychomotor Agitation | 1992 |