Page last updated: 2024-11-03

propofol and Adrenal Gland Hypofunction

propofol has been researched along with Adrenal Gland Hypofunction in 5 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" Patients were divided into two groups based on intraoperative anesthetic technique: sevoflurane-based inhalation anesthesia group (n = 74) and propofol-based intravenous anesthesia group (n = 355)."8.12Sevoflurane anesthesia rather than propofol anesthesia is associated with 3-month postoperative hypocortisolism in patients undergoing endoscopic transsphenoidal surgery for non-functional pituitary adenoma with preoperative normal hypothalamic-pituitary- ( Choi, S; Kim, N; Kim, YH; Kim, YJ; Oh, H; Park, HP, 2022)
"In elective cardiac surgery, laboratory indicators of etomidate-induced adrenal insufficiency do not translate into increased vasopressor requirement or inferior early outcomes."5.22Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial. ( Basciani, RM; Begert, E; Brander, L; Carrel, T; Eberle, B; Etter, R; Jakob, SM; Rindlisbacher, A, 2016)
"The consequences of inhibition of cortisol synthesis by a single dose of etomidate on subsequent vasopressor drug usage and the duration of relative adrenal insufficiency (RAI) after cardiac surgery are not known."5.15Haemodynamic consequences of etomidate administration in elective cardiac surgery: a randomized double-blinded study. ( Auboyer, C; Bayon, MC; Castelain, C; Lambert, P; Molliex, S; Morel, J; Salard, M; Vola, M, 2011)
" Patients were divided into two groups based on intraoperative anesthetic technique: sevoflurane-based inhalation anesthesia group (n = 74) and propofol-based intravenous anesthesia group (n = 355)."4.12Sevoflurane anesthesia rather than propofol anesthesia is associated with 3-month postoperative hypocortisolism in patients undergoing endoscopic transsphenoidal surgery for non-functional pituitary adenoma with preoperative normal hypothalamic-pituitary- ( Choi, S; Kim, N; Kim, YH; Kim, YJ; Oh, H; Park, HP, 2022)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Choi, S1
Kim, YJ1
Oh, H1
Kim, N1
Kim, YH1
Park, HP1
Basciani, RM1
Rindlisbacher, A1
Begert, E1
Brander, L1
Jakob, SM1
Etter, R1
Carrel, T1
Eberle, B1
Sweeney, DA1
Natanson, C1
Banks, SM1
Solomon, SB1
Behrend, EN1
Annane, D1
Morel, J1
Salard, M1
Castelain, C1
Bayon, MC1
Lambert, P1
Vola, M1
Auboyer, C1
Molliex, S1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Etomidate Versus Propofol As An Anesthesia Induction Agent For Patients Undergoing CABG Surgery, Assessing Hemodynamic Stability. A Single Blinded, Randomized Controlled Trial.[NCT06068764]Phase 4300 participants (Anticipated)Interventional2023-12-05Recruiting
Effect of an Anesthetic Induction Dose of Etomidate on Hemodynamics and Adrenocortical Function After Cardiac Surgery[NCT00415701]Phase 4130 participants (Anticipated)Interventional2006-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for propofol and Adrenal Gland Hypofunction

ArticleYear
Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial.
    European journal of anaesthesiology, 2016, Volume: 33, Issue:6

    Topics: Adrenal Insufficiency; Aged; Anesthesia; Anesthetics, Intravenous; Cardiac Surgical Procedures; Coro

2016
Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial.
    European journal of anaesthesiology, 2016, Volume: 33, Issue:6

    Topics: Adrenal Insufficiency; Aged; Anesthesia; Anesthetics, Intravenous; Cardiac Surgical Procedures; Coro

2016
Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial.
    European journal of anaesthesiology, 2016, Volume: 33, Issue:6

    Topics: Adrenal Insufficiency; Aged; Anesthesia; Anesthetics, Intravenous; Cardiac Surgical Procedures; Coro

2016
Anaesthetic induction with etomidate in cardiac surgery: A randomised controlled trial.
    European journal of anaesthesiology, 2016, Volume: 33, Issue:6

    Topics: Adrenal Insufficiency; Aged; Anesthesia; Anesthetics, Intravenous; Cardiac Surgical Procedures; Coro

2016
Haemodynamic consequences of etomidate administration in elective cardiac surgery: a randomized double-blinded study.
    British journal of anaesthesia, 2011, Volume: 107, Issue:4

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Aged; Anesthetics, Intravenous; Blood Pressure;

2011

Other Studies

3 other studies available for propofol and Adrenal Gland Hypofunction

ArticleYear
Sevoflurane anesthesia rather than propofol anesthesia is associated with 3-month postoperative hypocortisolism in patients undergoing endoscopic transsphenoidal surgery for non-functional pituitary adenoma with preoperative normal hypothalamic-pituitary-
    Acta neurochirurgica, 2022, Volume: 164, Issue:8

    Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Anesthesia; Humans; Hypothalamo-Hypophyseal Syst

2022
Defining normal adrenal function testing in the intensive care unit setting: a canine study.
    Critical care medicine, 2010, Volume: 38, Issue:2

    Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldosterone; Animals; Conscious

2010
Defining critical illness-related corticosteroid insufficiency: one step forward!
    Critical care medicine, 2010, Volume: 38, Issue:2

    Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aldosterone; Animals; Conscious

2010