propofol has been researched along with Acute Confusional Senile Dementia in 11 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to evaluate the effect of minocycline preadministration on cognitive dysfunction, hippocampal inflammatory response, and hippocampal senile dementia-related proteins induced by propofol anesthesia in aged rats." | 8.12 | Effects of Minocycline on Cognitive Impairment, Hippocampal Inflammatory Response, and Hippocampal Alzheimer's Related Proteins in Aged Rats after Propofol Anesthesia. ( Liang, X; Zhang, R, 2022) |
| "The aim of this study was to evaluate the effect of minocycline preadministration on cognitive dysfunction, hippocampal inflammatory response, and hippocampal senile dementia-related proteins induced by propofol anesthesia in aged rats." | 4.12 | Effects of Minocycline on Cognitive Impairment, Hippocampal Inflammatory Response, and Hippocampal Alzheimer's Related Proteins in Aged Rats after Propofol Anesthesia. ( Liang, X; Zhang, R, 2022) |
| "Propofol was administrated to the WT and AD Tg mice once a week for 8 or 12 weeks, respectively." | 1.40 | Chronic treatment with anesthetic propofol improves cognitive function and attenuates caspase activation in both aged and Alzheimer's disease transgenic mice. ( Dong, Y; Shao, H; Xia, W; Xie, Z; Yu, B; Zhang, Y, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (90.91) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Liang, X | 1 |
| Zhang, R | 1 |
| Pikwer, A | 1 |
| Castegren, M | 1 |
| Namdar, S | 1 |
| Blennow, K | 2 |
| Zetterberg, H | 2 |
| Mattsson, N | 1 |
| Mardini, F | 1 |
| Tang, JX | 1 |
| Li, JC | 1 |
| Arroliga, MJ | 1 |
| Eckenhoff, RG | 2 |
| Eckenhoff, MF | 2 |
| Woodhouse, A | 1 |
| Fernandez-Martos, CM | 1 |
| Atkinson, RAK | 1 |
| Hanson, KA | 1 |
| Collins, JM | 1 |
| O'Mara, AR | 1 |
| Terblanche, N | 1 |
| Skinner, MW | 1 |
| Vickers, JC | 1 |
| King, AE | 1 |
| Yang, M | 1 |
| Wang, Y | 1 |
| Liang, G | 1 |
| Xu, Z | 2 |
| Chu, CT | 1 |
| Wei, H | 1 |
| Anckarsäter, R | 1 |
| Anckarsäter, H | 1 |
| Bromander, S | 1 |
| Wass, C | 1 |
| Shao, H | 1 |
| Zhang, Y | 2 |
| Dong, Y | 2 |
| Yu, B | 1 |
| Xia, W | 1 |
| Xie, Z | 2 |
| Quiroga, C | 1 |
| Chaparro, RE | 1 |
| Karlnoski, R | 1 |
| Erasso, D | 1 |
| Gordon, M | 1 |
| Morgan, D | 1 |
| Bosco, G | 1 |
| Rubini, A | 1 |
| Parmagnani, A | 1 |
| Paoli, A | 1 |
| Mangar, D | 1 |
| Camporesi, EM | 1 |
| Berger, M | 1 |
| Nadler, JW | 1 |
| Friedman, A | 1 |
| McDonagh, DL | 1 |
| Bennett, ER | 1 |
| Cooter, M | 1 |
| Qi, W | 1 |
| Laskowitz, DT | 1 |
| Ponnusamy, V | 1 |
| Newman, MF | 1 |
| Shaw, LM | 1 |
| Warner, DS | 1 |
| Mathew, JP | 1 |
| James, ML | 1 |
| Zhen, Y | 1 |
| Yue, Y | 1 |
| Golde, TE | 1 |
| Tanzi, RE | 1 |
| Moir, RD | 1 |
| Ye, X | 1 |
| Lian, Q | 1 |
| Pan, JZ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Isoflurane Versus Propofol Anesthesia on Alzheimers Disease CSF Markers[NCT01640275] | Phase 1 | 105 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for propofol and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
The Effect of Propofol Versus Isoflurane Anesthesia on Human Cerebrospinal Fluid Markers of Alzheimer's Disease: Results of a Randomized Trial.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Anesthesia, Intravenous; Anesthetics, Intravenous; Biomark | 2016 |
10 other studies available for propofol and Acute Confusional Senile Dementia
| Article | Year |
|---|---|
Effects of Minocycline on Cognitive Impairment, Hippocampal Inflammatory Response, and Hippocampal Alzheimer's Related Proteins in Aged Rats after Propofol Anesthesia.
Topics: Alzheimer Disease; Anesthesia; Animals; Cognitive Dysfunction; Glycogen Synthase Kinase 3 beta; Hipp | 2022 |
Effects of surgery and propofol-remifentanil total intravenous anesthesia on cerebrospinal fluid biomarkers of inflammation, Alzheimer's disease, and neuronal injury in humans: a cohort study.
Topics: Adult; Alzheimer Disease; Amyloid beta-Peptides; Anesthesia, Intravenous; Biomarkers; Cohort Studies | 2017 |
Effects of propofol and surgery on neuropathology and cognition in the 3xTgAD Alzheimer transgenic mouse model.
Topics: Alzheimer Disease; Anesthesia, Inhalation; Animals; Brain; Cognition; Cognition Disorders; Disease M | 2017 |
Repeat propofol anesthesia does not exacerbate plaque deposition or synapse loss in APP/PS1 Alzheimer's disease mice.
Topics: Alzheimer Disease; Anesthetics, Intravenous; Animals; Blotting, Western; Brain; Disease Models, Anim | 2018 |
Alzheimer's Disease Presenilin-1 Mutation Sensitizes Neurons to Impaired Autophagy Flux and Propofol Neurotoxicity: Role of Calcium Dysregulation.
Topics: Adenosine Triphosphatases; Alzheimer Disease; Anesthetics, Intravenous; Animals; Autophagy; Calcium | 2019 |
Non-neurological surgery and cerebrospinal fluid biomarkers for neuronal and astroglial integrity.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Arthroplast | 2014 |
Chronic treatment with anesthetic propofol improves cognitive function and attenuates caspase activation in both aged and Alzheimer's disease transgenic mice.
Topics: Aging; Alzheimer Disease; Amyloidogenic Proteins; Animals; Brain; Caspases; Cell Line, Tumor; Cognit | 2014 |
Effects of repetitive exposure to anesthetics and analgesics in the Tg2576 mouse Alzheimer's model.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analgesics; Anesthetics; A | 2014 |
Anesthetic propofol attenuates the isoflurane-induced caspase-3 activation and Aβ oligomerization.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anesthetics, Inhalation; A | 2011 |
Differential general anesthetic effects on microglial cytokine expression.
Topics: Alzheimer Disease; Anesthetics; Cells, Cultured; Cytokines; Gene Expression Regulation; Humans; Infl | 2013 |