Page last updated: 2024-11-03

propofol and Acathisia, Drug-Induced

propofol has been researched along with Acathisia, Drug-Induced in 27 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
" This study tested whether the addition of an intra-operative low-dose infusion of dexmedetomidine to fentanyl treatment reduced the incidence of emergence delirium following desflurane anesthesia in children undergoing strabismus surgery."9.19Low-dose dexmedetomidine reduces emergence agitation after desflurane anaesthesia in children undergoing strabismus surgery. ( Kang, YR; Kim, J; Kim, SY; Koo, BN; Lee, JH, 2014)
" This, however, does not result in a reduced incidence of emergence delirium after sevoflurane anesthesia."9.12Midazolam does not reduce emergence delirium after sevoflurane anesthesia in children. ( Breschan, C; Jost, R; Likar, R; Platzer, M; Stettner, H, 2007)
" This study tested whether the addition of an intra-operative low-dose infusion of dexmedetomidine to fentanyl treatment reduced the incidence of emergence delirium following desflurane anesthesia in children undergoing strabismus surgery."5.19Low-dose dexmedetomidine reduces emergence agitation after desflurane anaesthesia in children undergoing strabismus surgery. ( Kang, YR; Kim, J; Kim, SY; Koo, BN; Lee, JH, 2014)
" This, however, does not result in a reduced incidence of emergence delirium after sevoflurane anesthesia."5.12Midazolam does not reduce emergence delirium after sevoflurane anesthesia in children. ( Breschan, C; Jost, R; Likar, R; Platzer, M; Stettner, H, 2007)
"Pain is a well known complication of propofol injection."5.08Modulating effects of lignocaine on propofol. ( Khoo, ST; Tham, CS, 1995)
"Propofol was better than fentanyl due to a lower incidence of nausea and vomiting."2.78Comparison of propofol and fentanyl administered at the end of anaesthesia for prevention of emergence agitation after sevoflurane anaesthesia in children. ( Kim, H; Kim, MS; Lee, JR; Moon, BE, 2013)
"Midazolam and propofol have been examined with the aim of reducing emergence agitation after sevoflurane anaesthesia."2.76Prophylactic use of midazolam or propofol at the end of surgery may reduce the incidence of emergence agitation after sevoflurane anaesthesia. ( Kim, YH; Lim, HJ; Yoon, SM; Yoon, SZ, 2011)
"Remifentanil is a new rapid-acting and ultra-short acting mu-opioid receptor agonist with few reports from use in children."2.69Total intravenous anaesthesia with propofol and remifentanil in paediatric patients: a comparison with a desflurane-nitrous oxide inhalation anaesthesia. ( Eichner, A; Grundmann, U; Larsen, R; Uth, M; Wilhelm, W, 1998)
"Pediatric migraine is a common, chronic, and disabling neurological disorder in children and adolescents."2.66Intravenous Migraine Treatment in Children and Adolescents. ( Hershey, AD; Kabbouche, M; Maconochie, I; Murphy, B; Qaiser, S; Werner, K, 2020)
"Propofol was effective when used throughout anaesthesia (RR 0."2.50Effects of sevoflurane versus other general anaesthesia on emergence agitation in children. ( Ahmed, S; Burgoyne, LL; Chooi, C; Costi, D; Cyna, AM; Ellwood, J; Larsson, JN; Middleton, P; Stephens, K; Strickland, P, 2014)
" Eight patients developed adverse reactions, 3 of which required further evaluation in the emergency department."1.37Safety of deep sedation in an urban oral and maxillofacial surgery training program. ( Braidy, HF; Singh, P; Ziccardi, VB, 2011)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's6 (22.22)18.2507
2000's8 (29.63)29.6817
2010's11 (40.74)24.3611
2020's1 (3.70)2.80

Authors

AuthorsStudies
Werner, K1
Qaiser, S1
Kabbouche, M1
Murphy, B1
Maconochie, I1
Hershey, AD1
Tan, D1
Xia, H1
Sun, S1
Wang, F1
Lee, JR2
Kim, MS2
Moon, BE2
Kim, H2
Narayanasamy, AK1
Ghori, A1
Kim, J1
Kim, SY1
Lee, JH1
Kang, YR1
Koo, BN1
Lim, BG1
Shen, FY1
Kim, YB1
Kim, WB1
Kim, YS1
Han, HC1
Lee, MK1
Kong, MH1
Kim, YI1
Zhou, Y1
Jin, X1
Kang, Y1
Liang, G1
Liu, T1
Deng, N1
Costi, D1
Cyna, AM1
Ahmed, S1
Stephens, K1
Strickland, P1
Ellwood, J1
Larsson, JN1
Chooi, C1
Burgoyne, LL1
Middleton, P1
Tsai, PS1
Hsu, YW1
Lin, CS1
Ko, YP1
Huang, CJ1
Bakhamees, HS1
Mercan, A1
El-Halafawy, YM1
Dahmani, S1
Stany, I1
Brasher, C1
Lejeune, C1
Bruneau, B1
Wood, C1
Nivoche, Y1
Constant, I1
Murat, I1
Braidy, HF1
Singh, P1
Ziccardi, VB1
Kim, YH1
Yoon, SZ1
Lim, HJ1
Yoon, SM1
Chiba, S1
Shima, T1
Murakami, N1
Kato, M1
Subramaniam, K1
Gowda, RM1
Rosa, U1
Nakayama, S1
Furukawa, H1
Yanai, H1
Santiveri, X1
Moltò, L1
Rodríguez, C1
Sandín, F1
Vilaplana, J1
Castillo, J1
Breschan, C1
Platzer, M1
Jost, R1
Stettner, H1
Likar, R1
Bhakta, P1
Goel, A1
Acharjee, P1
Biswas, BK1
Lieblich, SE1
Tham, CS1
Khoo, ST1
Grundmann, U1
Uth, M1
Eichner, A1
Wilhelm, W1
Larsen, R1
Beskow, A1
Westrin, P1
de Mello, WF1
Kirkman, E1
Imray, JM1
Hay, A1
Stark, RD1
Binks, SM1
Dutka, VN1
O'Connor, KM1
Arnstein, MJ1
Glen, JB1

Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Unit[NCT03194360]141 participants (Actual)Observational2015-12-01Completed
Emergence Delirium in Children: a Randomized Clinical Trial of Different Doses of Sevoflurane During Induction of Anesthesia[NCT02707016]80 participants (Anticipated)Interventional2015-12-31Recruiting
Investigation of the DNA Methylation Profile in Children Who Presented Emergence Delirium[NCT03787849]175 participants (Actual)Interventional2018-09-24Completed
Effect of Single-dose Dexmedetomidine on Emergence Agitation and Postoperative Behavior Changes After Sevoflurane Anesthesia in Children[NCT03596775]Early Phase 196 participants (Anticipated)Interventional2018-09-01Not yet recruiting
Prospective Cohort Study Evaluating Incidence and Correlation Between Pain and Emergence Delirium After Adenotonsillectomy in Preschool Children[NCT01096797]Phase 4150 participants (Actual)Interventional2009-11-30Completed
Caudal Versus Intravenous Magnesium Sulfate In The Prevention OF Emergence Agitation After Sevoflurane Anesthesia For Lower Abdominal Surgeries In Children.[NCT03846284]93 participants (Actual)Interventional2017-10-08Active, not recruiting
Effectivity of 0.5 mg/kg Propofol in the End of Anesthesia to Reduce the Incidence of Postanesthetic Emergence Agitation in Pediatric Patients Under General Inhalation Anesthesia[NCT03528954]54 participants (Actual)Interventional2018-05-31Completed
Changes of the Short Portable Mental Status Questionnaire (SPMSQ-E) After Ketamine Administration on Ophthalmic Surgery in Geriatric Population.[NCT02049411]Phase 280 participants (Actual)Interventional2013-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for propofol and Acathisia, Drug-Induced

ArticleYear
Intravenous Migraine Treatment in Children and Adolescents.
    Current pain and headache reports, 2020, Jul-08, Volume: 24, Issue:8

    Topics: Administration, Intravenous; Adolescent; Akathisia, Drug-Induced; Anesthetics, Local; Anti-Inflammat

2020
Effect of ancillary drugs on sevoflurane related emergence agitation in children undergoing ophthalmic surgery: a Bayesian network meta-analysis.
    BMC anesthesiology, 2019, 08-01, Volume: 19, Issue:1

    Topics: Akathisia, Drug-Induced; Analgesics; Anesthesia Recovery Period; Anesthetics, Inhalation; Bayes Theo

2019
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Effects of sevoflurane versus other general anaesthesia on emergence agitation in children.
    The Cochrane database of systematic reviews, 2014, Sep-12, Issue:9

    Topics: Adjuvants, Anesthesia; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Ane

2014
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Pharmacological prevention of sevoflurane- and desflurane-related emergence agitation in children: a meta-analysis of published studies.
    British journal of anaesthesia, 2010, Volume: 104, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesia; Anesthesia Recovery Period; Anesthetics, Inhalation; Anesthetics

2010
Methohexital versus propofol for outpatient anesthesia. Part I: Methohexital is superior.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 1995, Volume: 53, Issue:7

    Topics: Akathisia, Drug-Induced; Ambulatory Surgical Procedures; Anesthesia, Dental; Apnea; Drug Costs; Endo

1995

Trials

13 trials available for propofol and Acathisia, Drug-Induced

ArticleYear
Low-dose dexmedetomidine reduces emergence agitation after desflurane anaesthesia in children undergoing strabismus surgery.
    Yonsei medical journal, 2014, Volume: 55, Issue:2

    Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; C

2014
Midazolam and propofol used alone or sequentially for long-term sedation in critically ill, mechanically ventilated patients: a prospective, randomized study.
    Critical care (London, England), 2014, Jun-16, Volume: 18, Issue:3

    Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthetics, Intravenous; Critical Illness; Dru

2014
Ketamine but not propofol provides additional effects on attenuating sevoflurane-induced emergence agitation in midazolam premedicated pediatric patients.
    Paediatric anaesthesia, 2008, Volume: 18, Issue:11

    Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthetics, Dissociative; Anesthetics, Inhalat

2008
Combination effect of low dose fentanyl and propofol on emergence agitation in children following sevoflurane anesthesia.
    Saudi medical journal, 2009, Volume: 30, Issue:4

    Topics: Adenoidectomy; Akathisia, Drug-Induced; Analgesics, Opioid; Anesthetics, Inhalation; Child, Preschoo

2009
Prophylactic use of midazolam or propofol at the end of surgery may reduce the incidence of emergence agitation after sevoflurane anaesthesia.
    Anaesthesia and intensive care, 2011, Volume: 39, Issue:5

    Topics: Adolescent; Akathisia, Drug-Induced; Anesthesia; Anesthesia Recovery Period; Anesthetics, Inhalation

2011
Comparison of propofol and fentanyl administered at the end of anaesthesia for prevention of emergence agitation after sevoflurane anaesthesia in children.
    British journal of anaesthesia, 2013, Volume: 110, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Inhalation; Ane

2013
Comparison of propofol and fentanyl administered at the end of anaesthesia for prevention of emergence agitation after sevoflurane anaesthesia in children.
    British journal of anaesthesia, 2013, Volume: 110, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Inhalation; Ane

2013
Comparison of propofol and fentanyl administered at the end of anaesthesia for prevention of emergence agitation after sevoflurane anaesthesia in children.
    British journal of anaesthesia, 2013, Volume: 110, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Inhalation; Ane

2013
Comparison of propofol and fentanyl administered at the end of anaesthesia for prevention of emergence agitation after sevoflurane anaesthesia in children.
    British journal of anaesthesia, 2013, Volume: 110, Issue:2

    Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Inhalation; Ane

2013
[Effect of propofol on sevoflurane agitation in children].
    Masui. The Japanese journal of anesthesiology, 2003, Volume: 52, Issue:6

    Topics: Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, General; Anesthetics, Inhalation; A

2003
Propofol reduces the incidence of emergence agitation in preschool-aged children as well as in school-aged children: a comparison with sevoflurane.
    Journal of anesthesia, 2007, Volume: 21, Issue:1

    Topics: Age Factors; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthetics, Inhalation; Anestheti

2007
[Sedation and analgesia with propofol plus low-dose ketamine for retrobulbar block].
    Revista espanola de anestesiologia y reanimacion, 2006, Volume: 53, Issue:9

    Topics: Aged; Aged, 80 and over; Akathisia, Drug-Induced; Ambulatory Surgical Procedures; Analgesics, Non-Na

2006
Midazolam does not reduce emergence delirium after sevoflurane anesthesia in children.
    Paediatric anaesthesia, 2007, Volume: 17, Issue:4

    Topics: Administration, Rectal; Age Factors; Akathisia, Drug-Induced; Anesthesia, General; Anesthetics, Inha

2007
Modulating effects of lignocaine on propofol.
    Anaesthesia and intensive care, 1995, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Aged; Akathisia, Drug-Induced; Anesthesia, Intravenous; Female; Forearm; Hand; Hu

1995
Total intravenous anaesthesia with propofol and remifentanil in paediatric patients: a comparison with a desflurane-nitrous oxide inhalation anaesthesia.
    Acta anaesthesiologica Scandinavica, 1998, Volume: 42, Issue:7

    Topics: Adenoidectomy; Akathisia, Drug-Induced; Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthes

1998
Sevoflurane causes more postoperative agitation in children than does halothane.
    Acta anaesthesiologica Scandinavica, 1999, Volume: 43, Issue:5

    Topics: Adolescent; Age Factors; Akathisia, Drug-Induced; Anesthetics, Inhalation; Anesthetics, Intravenous;

1999

Other Studies

9 other studies available for propofol and Acathisia, Drug-Induced

ArticleYear
Comparison of propofol and fentanyl for preventing emergence agitation in children.
    British journal of anaesthesia, 2013, Volume: 111, Issue:1

    Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Female

2013
Emergence agitation after sevoflurane anaesthesia in children.
    British journal of anaesthesia, 2013, Volume: 111, Issue:1

    Topics: Akathisia, Drug-Induced; Analgesics, Opioid; Anesthesia, Inhalation; Anesthetics, Inhalation; Female

2013
Possible role of GABAergic depolarization in neocortical neurons in generating hyperexcitatory behaviors during emergence from sevoflurane anesthesia in the rat.
    ASN neuro, 2014, Apr-04, Volume: 6, Issue:2

    Topics: Age Factors; Akathisia, Drug-Induced; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Bu

2014
Safety of deep sedation in an urban oral and maxillofacial surgery training program.
    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons, 2011, Volume: 69, Issue:8

    Topics: Adjuvants, Anesthesia; Adult; Age Factors; Aggression; Akathisia, Drug-Induced; Ambulatory Surgical

2011
Delayed neuroexcitatory symptoms following propofol sedation in a patient with polysubstance abuse.
    Journal of clinical anesthesia, 2003, Volume: 15, Issue:5

    Topics: Akathisia, Drug-Induced; Alcoholism; Conscious Sedation; Electroencephalography; Humans; Hypnotics a

2003
Propofol for the management of glycine-mediated excitatory symptoms of TURP syndrome.
    European journal of anaesthesiology, 2008, Volume: 25, Issue:5

    Topics: Aged; Akathisia, Drug-Induced; Glycine; Glycine Agents; Humans; Hyperammonemia; Hypnotics and Sedati

2008
Propofol and excitatory sequelae in rats.
    Anaesthesia, 1992, Volume: 47, Issue:2

    Topics: Akathisia, Drug-Induced; Anesthesia, Intravenous; Animals; Male; Propofol; Rats; Rats, Inbred Strain

1992
Withdrawal syndrome after propofol.
    Anaesthesia, 1991, Volume: 46, Issue:8

    Topics: Akathisia, Drug-Induced; Female; Humans; Infant; Propofol; Substance Withdrawal Syndrome

1991
A review of the safety and tolerance of propofol ('Diprivan').
    Postgraduate medical journal, 1985, Volume: 61 Suppl 3

    Topics: Akathisia, Drug-Induced; Anesthesia, Intravenous; Drug Tolerance; Hematologic Tests; Humans; Hydroco

1985