propofol has been researched along with Academic Disorder, Developmental in 11 studies
Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There is an ongoing debate as to whether propofol exhibits pro- or anticonvulsant effects, and whether it should be used in patients with epilepsy." | 7.73 | Effect of propofol on seizure-like phenomena and electroencephalographic activity in children with epilepsy vs children with learning difficulties. ( Gortner, L; Gottschling, S; Grundmann, U; Kegel, B; Mencke, T; Meyer, S; Shamdeen, MG, 2006) |
| "3 mg/kg ketamine and then underwent ECT under propofol anesthesia, and a control group, which received isovolumetric placebo (normal saline) and then underwent ECT under propofol anesthesia." | 5.24 | Effect of Low Dose of Ketamine on Learning Memory Function in Patients Undergoing Electroconvulsive Therapy-A Randomized, Double-Blind, Controlled Clinical Study. ( Chen, J; Chen, Q; Hao, X; Li, X; Luo, Q; Meng, H; Min, S; Peng, L, 2017) |
| "There is an ongoing debate as to whether propofol exhibits pro- or anticonvulsant effects, and whether it should be used in patients with epilepsy." | 3.73 | Effect of propofol on seizure-like phenomena and electroencephalographic activity in children with epilepsy vs children with learning difficulties. ( Gortner, L; Gottschling, S; Grundmann, U; Kegel, B; Mencke, T; Meyer, S; Shamdeen, MG, 2006) |
| " Intralipid (10%, 10 mL/kg) for vehicle control and different dosage of propofol for three treatment groups (50, 100 and 200 mg/kg) were administered intraperitoneally." | 1.48 | PKA-CREB-BDNF signaling pathway mediates propofol-induced long-term learning and memory impairment in hippocampus of rats. ( Chen, J; Jiang, Y; Li, L; Pan, S; Qin, Y; Wei, Y; Xie, Y; Zhong, Y, 2018) |
| "The isoflurane anaesthesia treatment increased the escape latency contrast to propofol anaesthesia group." | 1.38 | Changes of learning and memory in aged rats after isoflurane inhalational anaesthesia correlated with hippocampal acetylcholine level. ( Feng, C; Jia, X; Wang, H; Wang, Y; Wu, A; Xu, Z; Yue, Y, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 9 (81.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, L | 1 |
| Wang, S | 1 |
| Feng, Y | 1 |
| Zhao, W | 2 |
| Zuo, W | 1 |
| Zhong, L | 1 |
| Lin, J | 1 |
| Luo, F | 1 |
| Zhong, Y | 1 |
| Chen, J | 3 |
| Li, L | 1 |
| Qin, Y | 1 |
| Wei, Y | 1 |
| Pan, S | 1 |
| Jiang, Y | 1 |
| Xie, Y | 1 |
| Yang, B | 1 |
| Liang, G | 1 |
| Khojasteh, S | 1 |
| Wu, Z | 1 |
| Yang, W | 1 |
| Joseph, D | 1 |
| Wei, H | 1 |
| Zhu, X | 1 |
| Hao, X | 2 |
| Luo, J | 1 |
| Min, S | 2 |
| Xie, F | 1 |
| Zhang, F | 1 |
| Zhang, J | 1 |
| Tan, H | 1 |
| Jiang, W | 1 |
| Zuo, Z | 1 |
| Liu, G | 1 |
| Liu, C | 2 |
| Zhang, XN | 1 |
| Liu, WF | 1 |
| Chen, Q | 1 |
| Peng, L | 1 |
| Meng, H | 1 |
| Luo, Q | 1 |
| Li, X | 1 |
| Wang, H | 1 |
| Xu, Z | 1 |
| Feng, C | 1 |
| Wang, Y | 1 |
| Jia, X | 1 |
| Wu, A | 1 |
| Yue, Y | 1 |
| Meyer, S | 1 |
| Shamdeen, MG | 1 |
| Kegel, B | 1 |
| Mencke, T | 1 |
| Gottschling, S | 1 |
| Gortner, L | 1 |
| Grundmann, U | 1 |
| Baxter, MG | 1 |
| Murphy, KL | 1 |
| Crosby, G | 1 |
| Culley, DJ | 1 |
1 trial available for propofol and Academic Disorder, Developmental
| Article | Year |
|---|---|
Effect of Low Dose of Ketamine on Learning Memory Function in Patients Undergoing Electroconvulsive Therapy-A Randomized, Double-Blind, Controlled Clinical Study.
Topics: Adolescent; Adult; Aged; Anesthesia; Anesthetics, Intravenous; Asian People; Depressive Disorder, Ma | 2017 |
10 other studies available for propofol and Academic Disorder, Developmental
| Article | Year |
|---|---|
KIF17 mediates the learning and memory impairment in offspring induced by maternal exposure to propofol during middle pregnancy.
Topics: Animals; Biomarkers; Disease Models, Animal; Female; Hippocampus; Kinesins; Learning Disabilities; M | 2018 |
PKA-CREB-BDNF signaling pathway mediates propofol-induced long-term learning and memory impairment in hippocampus of rats.
Topics: Animals; Animals, Newborn; Apoptosis; Brain-Derived Neurotrophic Factor; CREB-Binding Protein; Cycli | 2018 |
Comparison of neurodegeneration and cognitive impairment in neonatal mice exposed to propofol or isoflurane.
Topics: Administration, Inhalation; Anesthetics; Animals; Animals, Newborn; Apoptosis; Brain Damage, Chronic | 2014 |
Propofol inhibits inflammatory cytokine-mediated glutamate uptake dysfunction to alleviate learning/memory impairment in depressed rats undergoing electroconvulsive shock.
Topics: Analysis of Variance; Animals; Cytokines; Depression; Disease Models, Animal; Food Deprivation; Food | 2015 |
The choice of general anesthetics may not affect neuroinflammation and impairment of learning and memory after surgery in elderly rats.
Topics: Anesthetics, General; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Buprenorphine; Cal | 2015 |
Comparison of the neuropsychological mechanisms of 2,6-diisopropylphenol and N-methyl-D-aspartate receptor antagonist against electroconvulsive therapy-induced learning and memory impairment in depressed rats.
Topics: Animals; Depressive Disorder; Dizocilpine Maleate; Electroconvulsive Therapy; Excitatory Amino Acid | 2015 |
Propofol can Protect Against the Impairment of Learning-memory Induced by Electroconvulsive Shock via Tau Protein Hyperphosphorylation in Depressed Rats.
Topics: Animals; Depression; Dizocilpine Maleate; Electroshock; Glutamic Acid; Learning Disabilities; Male; | 2015 |
Changes of learning and memory in aged rats after isoflurane inhalational anaesthesia correlated with hippocampal acetylcholine level.
Topics: Acetylcholine; Aging; Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Brain; Brain Chemi | 2012 |
Effect of propofol on seizure-like phenomena and electroencephalographic activity in children with epilepsy vs children with learning difficulties.
Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Drug Administration Schedule; Electroencephalo | 2006 |
Different behavioral effects of neurotoxic dorsal hippocampal lesions placed under either isoflurane or propofol anesthesia.
Topics: Anesthetics, Inhalation; Anesthetics, Intravenous; Animals; Behavior, Animal; Denervation; Hippocamp | 2008 |