Page last updated: 2024-11-03

propofol and 2019 Novel Coronavirus Disease

propofol has been researched along with 2019 Novel Coronavirus Disease in 30 studies

Propofol: An intravenous anesthetic agent which has the advantage of a very rapid onset after infusion or bolus injection plus a very short recovery period of a couple of minutes. (From Smith and Reynard, Textbook of Pharmacology, 1992, 1st ed, p206). Propofol has been used as ANTICONVULSANTS and ANTIEMETICS.
propofol : A phenol resulting from the formal substitution of the hydrogen at the 2 position of 1,3-diisopropylbenzene by a hydroxy group.

Research Excerpts

ExcerptRelevanceReference
"A higher-than-usual resistance to standard sedation regimens in COVID-19 patients suffering from acute respiratory distress syndrome (ARDS) has led to the frequent use of the second-line anaesthetic agent ketamine."8.12Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome. ( Andermatt, R; Bartussek, J; Buehler, PK; Camen, G; David, S; Erlebach, R; Hofmaenner, DA; Jüngst, C; Müllhaupt, B; Schuepbach, RA; Wendel-Garcia, PD, 2022)
"Propofol was promptly discontinued."5.91Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19. ( Henley, E; Siddiqui, MN; Xue, B, 2023)
"Status Epilepticus is the most common non-traumatic neurologic emergency in childhood."5.72Resolution of status epilepticus after ketamine administration. ( Hakmeh, W; Howing, CE; Razi, F, 2022)
"A higher-than-usual resistance to standard sedation regimens in COVID-19 patients suffering from acute respiratory distress syndrome (ARDS) has led to the frequent use of the second-line anaesthetic agent ketamine."4.12Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome. ( Andermatt, R; Bartussek, J; Buehler, PK; Camen, G; David, S; Erlebach, R; Hofmaenner, DA; Jüngst, C; Müllhaupt, B; Schuepbach, RA; Wendel-Garcia, PD, 2022)
"Hypertriglyceridemia occurred frequently in patients with COVID-19 who received propofol but did not lead to acute pancreatitis."4.12The Safety of Continuous Infusion Propofol in Mechanically Ventilated Adults With Coronavirus Disease 2019. ( Abedian, S; An, A; Barie, PS; Berger, K; Littlefield, AJ; Witenko, CJ, 2022)
"Propofol was infused at 1."1.91Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS. ( Babu, VK; Garcia-Fernandez, A; Perez Del Nogal, G; Rojas, P, 2023)
"Propofol was promptly discontinued."1.91Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19. ( Henley, E; Siddiqui, MN; Xue, B, 2023)
"Propofol was exclusively administered by anesthetists according to 94% of answers, and for 6% of respondents the endoscopist is allowed to administer propofol in presence of a dedicated nurse, but with a readily available anesthetist."1.91Rethink analgo-sedation in digestive endoscopy: the role of scientific societies in tracing training path. ( Conigliaro, R; De Robertis, E; Fanti, L; Martino, R; Monzani, R; Pasquale, L; Petrini, F; Pietrini, L; Rossi, M; Sbaraglia, F; Tritapepe, L, 2023)
"Phenobarbital was trialed for possible propofol withdrawal syndrome, allowing for a dose reduction of 10 μg/kg/min within 2 hours of the first dose without any corresponding symptoms."1.91Successful management of suspected propofol dependence with phenobarbital in an adult patient with COVID-19. ( Feeney, ME; Steiling, K, 2023)
"Status Epilepticus is the most common non-traumatic neurologic emergency in childhood."1.72Resolution of status epilepticus after ketamine administration. ( Hakmeh, W; Howing, CE; Razi, F, 2022)
"Pneumonia caused by coronavirus disease 2019 (COVID-19) is a highly contagious disease."1.62A Case Report of Sedation Strategy for a Patient With Coronavirus Disease 2019 Supported by Extracorporeal Membrane Oxygenation After Cesarean Section. ( Cheng, Z; Li, B; Liao, X; Wen, J, 2021)

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's30 (100.00)2.80

Authors

AuthorsStudies
El Nekidy, WS1
Shatnawei, A1
Abdelsalam, MM1
Hassan, M1
Dajani, RZ1
Salem, N1
St John, TJL1
Rahman, N1
Hamed, F1
Mallat, J1
Witenko, CJ2
Littlefield, AJ2
Abedian, S2
An, A2
Barie, PS2
Berger, K2
Sohn, JT2
Howing, CE1
Razi, F1
Hakmeh, W1
Viana, MV1
Pantet, O1
Charrière, M1
Favre, D1
Piquilloud, L1
Schneider, AG1
Hurni, CA1
Berger, MM1
Wendel-Garcia, PD1
Erlebach, R1
Hofmaenner, DA1
Camen, G1
Schuepbach, RA1
Jüngst, C1
Müllhaupt, B1
Bartussek, J1
Buehler, PK1
Andermatt, R1
David, S1
Koutsogiannaki, S1
Bu, W1
Maisat, W1
Manzor, M1
Zhang, Z1
Ohto, U1
Eckenhoff, RG1
Yuki, K1
Wiemann, B3
Mitchell, J3
Sarangarm, P3
Miskimins, R3
Babu, VK1
Rojas, P1
Perez Del Nogal, G1
Garcia-Fernandez, A1
Rooimans, T1
Damen, M1
Markesteijn, CMA1
Schuurmans, CCL1
de Zoete, NHC1
van Hasselt, PM1
Hennink, WE1
van Nostrum, CF1
Hermes, M1
Besseling, R1
Vromans, H1
Siddiqui, MN1
Henley, E1
Xue, B1
Rossi, M1
Tritapepe, L1
Conigliaro, R1
Fanti, L1
Monzani, R1
De Robertis, E1
Martino, R1
Pietrini, L1
Sbaraglia, F1
Pasquale, L1
Petrini, F1
Feeney, ME1
Steiling, K1
Payen, JF1
Chanques, G1
Futier, E1
Velly, L1
Jaber, S1
Constantin, JM1
Lönnqvist, PA1
Bell, M1
Karlsson, T1
Wiklund, L1
Höglund, AS1
Larsson, L1
Soh, M2
Hifumi, T2
Isokawa, S2
Shimizu, M2
Otani, N2
Ishimatsu, S2
Jiang, S1
Petriceks, AH1
Burke, H1
Stern, TA1
Senthilkumaran, S1
Koushik, M1
Sanjay, P1
Thirumalaikolundusubramanian, P1
Charbonneau, H1
Mrozek, S1
Pradere, B1
Cornu, JN1
Misrai, V1
Lucchetta, V1
Bonvicini, D1
Ballin, A1
Tiberio, I1
Hirota, K1
Lambert, DG1
Yamamoto, K1
Liao, X1
Cheng, Z1
Wen, J1
Li, B1
Wei, P1
Zheng, Q1
Ye, H1
Lyu, W1
Li, J1
Yang, JJ1
Kermad, A1
Speltz, J1
Danziger, G1
Mertke, T1
Bals, R1
Volk, T1
Lepper, PM1
Meiser, A1
Waters, TW1
Dickens, DS1
Gutierrez, J1
Sepulveda, W1
Ramirez, R1
Acosta, G1
Ambiado, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Assessment of Analgesics and Sedatives in Mechanically Ventilated Patients With COVID-19[NCT05336656]353 participants (Actual)Observational2022-01-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for propofol and 2019 Novel Coronavirus Disease

ArticleYear
Sedation for critically ill patients with COVID-19: Which specificities? One size does not fit all.
    Anaesthesia, critical care & pain medicine, 2020, Volume: 39, Issue:3

    Topics: Analgesics, Opioid; Betacoronavirus; Coronavirus Infections; COVID-19; Critical Illness; Deep Sedati

2020

Other Studies

29 other studies available for propofol and 2019 Novel Coronavirus Disease

ArticleYear
Hypertriglyceridemia in Critically Ill Patients With SARS-CoV-2 Infection.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:6

    Topics: Adult; COVID-19; Critical Illness; Female; Humans; Hypertriglyceridemia; Intensive Care Units; Lipas

2022
Reply: The Safety of Continuous Infusion Propofol in Mechanically Ventilated Adults With Coronavirus Disease 2019.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:5

    Topics: Adult; COVID-19; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Respiration, Artif

2022
Comment: The Safety of Continuous Infusion Propofol in Mechanically Ventilated Adults With Coronavirus Disease 2019.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:5

    Topics: Adult; COVID-19; Humans; Hypnotics and Sedatives; Intensive Care Units; Propofol; Respiration, Artif

2022
Resolution of status epilepticus after ketamine administration.
    The American journal of emergency medicine, 2022, Volume: 54

    Topics: Aftercare; Anticonvulsants; COVID-19; Female; Humans; Infant; Ketamine; Levetiracetam; Lorazepam; Pa

2022
Specific nutrition and metabolic characteristics of critically ill patients with persistent COVID-19.
    JPEN. Journal of parenteral and enteral nutrition, 2022, Volume: 46, Issue:5

    Topics: Aged; COVID-19; Critical Illness; Energy Intake; Female; Humans; Intensive Care Units; Male; Middle

2022
Long-term ketamine infusion-induced cholestatic liver injury in COVID-19-associated acute respiratory distress syndrome.
    Critical care (London, England), 2022, 05-23, Volume: 26, Issue:1

    Topics: Bilirubin; COVID-19; Critical Illness; Humans; Hypnotics and Sedatives; Ketamine; Liver; Propofol; R

2022
Propofol directly binds to and inhibits TLR7.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36, Issue:8

    Topics: Animals; COVID-19; Dendritic Cells; Humans; Hypnotics and Sedatives; Imiquimod; Interferon-alpha; In

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sed

2022
Unusual case of propofol-related infusion syndrome complicating severe COVID-19 ARDS.
    BMJ case reports, 2023, Feb-07, Volume: 16, Issue:2

    Topics: Acidosis; Aged; COVID-19; Humans; Hyperlipidemias; Hypertriglyceridemia; Male; Propofol; Propofol In

2023
Development of a compounded propofol nanoemulsion using multiple non-invasive process analytical technologies.
    International journal of pharmaceutics, 2023, Jun-10, Volume: 640

    Topics: COVID-19; Emulsions; Humans; Pandemics; Parenteral Nutrition; Propofol

2023
Refractory atrial fibrillation with rapid ventricular response as a heralding sign of propofol infusion syndrome in a patient with COVID-19.
    BMJ case reports, 2023, May-04, Volume: 16, Issue:5

    Topics: Atrial Fibrillation; COVID-19; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Prop

2023
Rethink analgo-sedation in digestive endoscopy: the role of scientific societies in tracing training path.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:10

    Topics: Anesthesia; Conscious Sedation; COVID-19; Endoscopy, Gastrointestinal; Humans; Hypnotics and Sedativ

2023
Successful management of suspected propofol dependence with phenobarbital in an adult patient with COVID-19.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2023, 09-22, Volume: 80, Issue:19

    Topics: Adult; COVID-19; Dexmedetomidine; Fentanyl; Humans; Hypertension; Hypnotics and Sedatives; Male; Mid

2023
Does prolonged propofol sedation of mechanically ventilated COVID-19 patients contribute to critical illness myopathy?
    British journal of anaesthesia, 2020, Volume: 125, Issue:3

    Topics: Animals; Betacoronavirus; Coronavirus Infections; COVID-19; Critical Illness; Humans; Hypnotics and

2020
The authors' response: Propofol and sedation in patients with coronavirus disease 2019.
    The American journal of emergency medicine, 2021, Volume: 42

    Topics: Conscious Sedation; Coronavirus; COVID-19; Humans; Hypnotics and Sedatives; Propofol; SARS-CoV-2

2021
Weaning From Exogenous Sedation in the Era of COVID-19 Infection: Recommendations for Sedation and Its Discontinuation.
    The primary care companion for CNS disorders, 2020, Jul-16, Volume: 22, Issue:4

    Topics: Adult; Analgesics, Opioid; Benzodiazepines; Betacoronavirus; Coronavirus Infections; COVID-19; Depre

2020
The authors' response: Propofol in COVID 19: From basic science to clinical impact.
    The American journal of emergency medicine, 2021, Volume: 45

    Topics: COVID-19; Humans; Hypnotics and Sedatives; Neuroleptic Malignant Syndrome; Propofol; SARS-CoV-2

2021
Propofol in COVID 19 - From basic science to clinical impact.
    The American journal of emergency medicine, 2021, Volume: 45

    Topics: COVID-19; Humans; Hypnotics and Sedatives; Propofol; SARS-CoV-2

2021
Propofol and sedation in patients with coronavirus disease.
    The American journal of emergency medicine, 2021, Volume: 42

    Topics: Conscious Sedation; Coronavirus; COVID-19; Humans; Hypnotics and Sedatives; Neuroleptic Malignant Sy

2021
How to resume elective surgery in light of COVID-19 post-pandemic propofol shortage: The common concern of anaesthesists and surgeons.
    Anaesthesia, critical care & pain medicine, 2020, Volume: 39, Issue:5

    Topics: Anesthesia, Conduction; Anesthetics, Intravenous; Anesthetists; Attitude of Health Personnel; Betaco

2020
Propofol infusion syndrome in severe COVID-19.
    British journal of anaesthesia, 2020, Volume: 125, Issue:5

    Topics: Betacoronavirus; Conscious Sedation; Coronavirus Infections; COVID-19; Critical Illness; Humans; Hyp

2020
Propofol and SARS-CoV-2 infection.
    British journal of anaesthesia, 2020, Volume: 125, Issue:6

    Topics: Anesthetics, Intravenous; Coronavirus Infections; COVID-19; Critical Illness; Drug Repositioning; Hu

2020
Risk of propofol use for sedation in COVID-19 patient.
    Anaesthesiology intensive therapy, 2020, Volume: 52, Issue:4

    Topics: Animals; Betacoronavirus; Conscious Sedation; Coronavirus Infections; COVID-19; Humans; Hypnotics an

2020
A Case Report of Sedation Strategy for a Patient With Coronavirus Disease 2019 Supported by Extracorporeal Membrane Oxygenation After Cesarean Section.
    The heart surgery forum, 2021, 01-14, Volume: 24, Issue:1

    Topics: Cesarean Section; Combined Modality Therapy; COVID-19; Dexmedetomidine; Extracorporeal Membrane Oxyg

2021
Putative antiviral effects of propofol in COVID-19.
    British journal of anaesthesia, 2021, Volume: 126, Issue:5

    Topics: Anesthetics, Intravenous; Angiotensin-Converting Enzyme 2; Antiviral Agents; COVID-19; COVID-19 Drug

2021
The Safety of Continuous Infusion Propofol in Mechanically Ventilated Adults With Coronavirus Disease 2019.
    The Annals of pharmacotherapy, 2022, Volume: 56, Issue:1

    Topics: Acute Disease; Adult; COVID-19; Humans; Intensive Care Units; Pancreatitis; Propofol; Respiration, A

2022
Comparison of isoflurane and propofol sedation in critically ill COVID-19 patients-a retrospective chart review.
    Journal of anesthesia, 2021, Volume: 35, Issue:5

    Topics: Conscious Sedation; COVID-19; Critical Illness; Humans; Hypnotics and Sedatives; Intensive Care Unit

2021
Reducing sedated lumbar punctures in pediatric patients with acute lymphoblastic leukemia.
    Pediatric blood & cancer, 2021, Volume: 68, Issue:11

    Topics: Adolescent; Adult; Child; COVID-19; Female; Humans; Hypnotics and Sedatives; Male; Pain Management;

2021
Fetal Bladder Rupture as a Complication of Adjunctive Therapy in Severe Maternal SARS-CoV-2 Pneumonia.
    Fetal and pediatric pathology, 2022, Volume: 41, Issue:5

    Topics: Adult; Analgesics, Opioid; COVID-19; Dexmedetomidine; Female; Fentanyl; Humans; Midazolam; Pregnancy

2022