propiverine has been researched along with Muscle Contraction in 34 studies
propiverine: anticholinergic used for overactive bladder syndrome
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propiverine is a muscarinic receptor antagonist possessing additional properties, i." | 1.37 | The muscarinic receptor antagonist propiverine exhibits α(1)-adrenoceptor antagonism in human prostate and porcine trigonum. ( Braeter, M; Michel, MC; Michel-Reher, MB; Propping, S; Ravens, U; Strugala, GJ; Wirth, MP; Witte, LP; Wuest, M, 2011) |
| "Muscle contraction was measured with a force transducer; L-type Ca2+ currents (ICa,L) of isolated detrusor myocytes were recorded with standard voltage clamp technique." | 1.35 | Muscarinic receptor expression and receptor-mediated detrusor contraction: comparison of juvenile and adult porcine tissue. ( Braeter, M; Eichhorn, B; Michel, MC; Ravens, U; Strugala, G; Wuest, M, 2008) |
| "Pretreatment with propiverine and tolterodine caused parallel shifts to the right of the concentration-response curves to carbachol." | 1.35 | Pharmacological effects of propiverine and its active metabolite, M-1, on isolated human urinary bladder smooth muscle, and on bladder contraction in rats. ( Inadome, A; Maeda, Y; Masunaga, K; Nagata, T; Satoji, Y; Sugiyama, Y; Ueda, S; Yoshida, M, 2008) |
| "Propiverine was identified to be an inhibitor of the protein kinase C." | 1.33 | The anticholinergic drug propiverine inhibits the protein kinase C activity in the rat urinary bladder. ( Giessmann, T; May, K; Möritz, KU; Siegmund, W; Walter, R, 2005) |
| "Propiverine is a commonly used antimuscarinic drug used as therapy for symptoms of an overactive bladder." | 1.33 | Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction. ( Braeter, M; Hakenberg, OW; Kelly, LU; Ravens, U; Waelbroeck, M; Weiss, A; Wuest, M, 2006) |
| "To evaluate type of neurogenic bladder and to observe changes of autonomous detrusor contraction (ADC) after the normalization of the compliance and capacity of the bladder in cauda equina injury." | 1.31 | Significance of low compliance bladder in cauda equina injury. ( Kim, HJ; Lee, IY; Park, CI; Shin, JC, 2002) |
| "Propiverine is a drug for the treatment of incontinence and pollakiuria." | 1.30 | [Effects of propiverine hydrochloride (propiverine) on isolated rat and dog urinary bladder]. ( Kaneko, S; Nakano, D; Nishimori, T; Ohara, M, 1999) |
| " At doses of 10(-6) or 10(-5) M, P-4 shifted the dose-response curve for acetylcholine (ACh) to the right, and at a dose of 10(-5) M, it also inhibited the maximum response of ACh." | 1.28 | [Effects of propiverine hydrochloride and its metabolites on isolated guinea pig urinary bladder]. ( Haruno, A; Iriki, M; Kosaka, M; Miyake, H; Miyoshi, K; Nagai, M; Tsuchiya, K; Yamasaki, Y, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (17.65) | 18.7374 |
| 1990's | 6 (17.65) | 18.2507 |
| 2000's | 18 (52.94) | 29.6817 |
| 2010's | 4 (11.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Propping, S | 2 |
| Braeter, M | 6 |
| Grimm, MO | 1 |
| Wirth, MP | 3 |
| Ravens, U | 7 |
| Wuest, M | 6 |
| Witte, LP | 1 |
| Michel-Reher, MB | 1 |
| Strugala, GJ | 1 |
| Michel, MC | 2 |
| Sugaya, K | 5 |
| Nishijima, S | 5 |
| Kadekawa, K | 3 |
| Ashitomi, K | 2 |
| Yamamoto, H | 2 |
| Wüst, M | 1 |
| Averbeck, B | 1 |
| Reif, S | 1 |
| Bräter, M | 1 |
| Shin, JC | 1 |
| Park, CI | 1 |
| Kim, HJ | 1 |
| Lee, IY | 1 |
| Shimizu, I | 1 |
| Kawashima, K | 1 |
| Ishii, D | 1 |
| Oka, M | 1 |
| Möritz, KU | 1 |
| Walter, R | 1 |
| May, K | 1 |
| Giessmann, T | 1 |
| Siegmund, W | 2 |
| Miyazato, M | 3 |
| Shimabukuro, S | 1 |
| Morozumi, M | 1 |
| Ogawa, Y | 3 |
| Hecht, J | 1 |
| Christ, T | 1 |
| Schoeberl, C | 2 |
| Hakenberg, OW | 2 |
| Weiss, A | 1 |
| Waelbroeck, M | 1 |
| Kelly, LU | 2 |
| Oda, M | 1 |
| Ohtake, A | 1 |
| Saitoh, C | 1 |
| Yuyama, H | 1 |
| Ukai, M | 1 |
| Okutsu, H | 1 |
| Noguchi, Y | 1 |
| Hatanaka, T | 1 |
| Suzuki, M | 1 |
| Sato, S | 1 |
| Sasamata, M | 1 |
| Miyata, K | 1 |
| Scheepe, JR | 1 |
| van den Hoek, J | 1 |
| Jünemann, KP | 1 |
| Alken, P | 1 |
| Takayanagi, R | 1 |
| Mizushima, H | 1 |
| Ozeki, T | 1 |
| Yokoyama, H | 1 |
| Iga, T | 1 |
| Yamada, Y | 1 |
| Yokoyama, O | 1 |
| Miwa, Y | 1 |
| Oyama, N | 1 |
| Aoki, Y | 1 |
| Ito, H | 1 |
| Akino, H | 1 |
| Tasaki, S | 1 |
| Eichhorn, B | 1 |
| Strugala, G | 1 |
| Sugiyama, Y | 1 |
| Yoshida, M | 2 |
| Masunaga, K | 1 |
| Satoji, Y | 1 |
| Maeda, Y | 1 |
| Nagata, T | 1 |
| Inadome, A | 2 |
| Ueda, S | 2 |
| Nagai, M | 4 |
| Nakajima, M | 1 |
| Usuda, S | 1 |
| Iriki, M | 4 |
| Wehnert, J | 1 |
| Sage, S | 1 |
| Tokuno, H | 1 |
| Chowdhury, JU | 1 |
| Tomita, T | 1 |
| Yono, M | 1 |
| Wada, Y | 1 |
| Kikukawa, H | 1 |
| Takahashi, W | 1 |
| Seshita, H | 1 |
| Kaneko, S | 3 |
| Nakano, D | 1 |
| Ohara, M | 1 |
| Nishimori, T | 1 |
| Doi, T | 2 |
| Kamo, I | 2 |
| Imai, S | 2 |
| Okanishi, S | 2 |
| Ikeura, Y | 1 |
| Natsugari, H | 1 |
| Haruno, A | 4 |
| Nigussie, M | 1 |
| Tilahun, K | 1 |
| Aitenfissu, H | 1 |
| Franke, G | 1 |
| Wengler, A | 1 |
| Suzuki, N | 1 |
| Kitazato, K | 1 |
| Yamazaki, Y | 1 |
| Tsuchiya, K | 2 |
| Kosaka, M | 2 |
| Yamasaki, Y | 1 |
| Miyoshi, K | 1 |
| Miyake, H | 1 |
| Nomura, N | 1 |
| Hamakawa, T | 1 |
| Riotte, J | 1 |
| Mutschler, E | 1 |
34 other studies available for propiverine and Muscle Contraction
| Article | Year |
|---|---|
Anticholinergic effects of cis- and trans-isomers of two metabolites of propiverine.
Topics: Animals; Benzilates; Calcium; Carbachol; Cholinergic Antagonists; Dose-Response Relationship, Drug; | 2010 |
The muscarinic receptor antagonist propiverine exhibits α(1)-adrenoceptor antagonism in human prostate and porcine trigonum.
Topics: Adrenergic alpha-1 Receptor Antagonists; Aged; Animals; Benzilates; Calcium; Calcium Channel Blocker | 2011 |
Effect of distigmine combined with propiverine on bladder activity in rats with spinal cord injury.
Topics: Animals; Benzilates; Cholinergic Antagonists; Drug Therapy, Combination; Female; Muscle Contraction; | 2012 |
Excitatory effect of propiverine hydrochloride on urethral activity in rats.
Topics: Adrenergic alpha-Antagonists; Animals; Benzilates; Female; Imidazoles; Indoles; Muscarinic Antagonis | 2012 |
Different responses to drugs against overactive bladder in detrusor muscle of pig, guinea pig and mouse.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cholinergic Agonists; Cholinergic An | 2002 |
Significance of low compliance bladder in cauda equina injury.
Topics: Administration, Intravesical; Administration, Oral; Adult; Benzilates; Cauda Equina; Compliance; Fem | 2002 |
Urodynamics in a rat neurogenic bladder model with a unilateral electrolytic lesion of the basal forebrain.
Topics: Animals; Benzilates; Brain Diseases; Cholinergic Antagonists; Disease Models, Animal; Fumarates; Mal | 2003 |
The anticholinergic drug propiverine inhibits the protein kinase C activity in the rat urinary bladder.
Topics: Animals; Benzilates; Cell Membrane; Enzyme Inhibitors; Liver; Male; Muscle Contraction; Muscle Relax | 2005 |
Activation of the rostral pontine reticular formation increases the spinal glycine level and inhibits bladder contraction in rats.
Topics: Animals; Benzilates; Carbachol; Flavoxate; Glycine; Muscle Contraction; Rats; Rats, Sprague-Dawley; | 2005 |
Pharmacodynamics of propiverine and three of its main metabolites on detrusor contraction.
Topics: Aged; Aged, 80 and over; Animals; Atropine; Benzilates; Biotransformation; Calcium Channels, L-Type; | 2005 |
Juvenile pig detrusor: effects of propiverine and three of its metabolites.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cresols; Dose-Response Relationship, | 2005 |
Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction.
Topics: Animals; Benzilates; Binding, Competitive; Calcium; Carbachol; Cell Line; Cells, Cultured; CHO Cells | 2006 |
A gap junction blocker inhibits isolated whole bladder activity in normal rats and rats with partial bladder outlet obstruction.
Topics: Animals; Benzilates; Female; Gap Junctions; Glycyrrhetinic Acid; In Vitro Techniques; Muscle Contrac | 2006 |
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; C | 2007 |
A standardised mini pig model for in vivo investigations of anticholinergic effects on bladder function and salivation.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Blood Pressure; Cholinergic Antagonists; Cresol | 2007 |
Analysis of pharmacological effects of drugs used for treatment of urinary disturbance based on anticholinergic and smooth muscle-relaxing effects.
Topics: Animals; Benzilates; Butylamines; Guinea Pigs; Humans; Mandelic Acids; Muscarinic Antagonists; Muscl | 2007 |
Antimuscarinic drug inhibits detrusor overactivity induced by topical application of prostaglandin E2 to the urethra with a decrease in urethral pressure.
Topics: Administration, Intravesical; Administration, Topical; Adrenergic alpha-Antagonists; Animals; Atropi | 2007 |
Effects of propiverine and naftopidil on the urinary ATP level and bladder activity after bladder stimulation in rats.
Topics: Acetic Acid; Adenosine Triphosphate; Adrenergic alpha-Antagonists; Animals; Benzilates; Cholinergic | 2007 |
Muscarinic receptor expression and receptor-mediated detrusor contraction: comparison of juvenile and adult porcine tissue.
Topics: Aging; Animals; Benzilates; Calcium; Cholinergic Antagonists; Muscarinic Antagonists; Muscle Contrac | 2008 |
Pharmacological effects of propiverine and its active metabolite, M-1, on isolated human urinary bladder smooth muscle, and on bladder contraction in rats.
Topics: Aged; Animals; Benzhydryl Compounds; Benzilates; Carbachol; Cholinergic Agonists; Cresols; Cyclic N- | 2008 |
Inhibitory effect of alpha-alpha-diphenyl-alpha-propoxyacetic acid-L-methyl-4-piperidyl ester hydrochloride on the activity of the rat urinary bladder.
Topics: Animals; Benzilates; Efferent Pathways; Male; Muscle Contraction; Parasympathetic Nervous System; Ra | 1983 |
[Therapy of detrusor hyperactivity with propiverin (mictonorm)].
Topics: Benzilates; Humans; Hydrostatic Pressure; Manometry; Muscle Contraction; Parasympatholytics; Urinary | 1981 |
Inhibitory effects of propiverine on rat and guinea-pig urinary bladder muscle.
Topics: Animals; Atropine; Benzilates; Calcium Channel Blockers; Calcium Channels; Carbachol; Female; Guinea | 1993 |
Pharmacological effects of tolterodine on human isolated urinary bladder.
Topics: Aged; Benzhydryl Compounds; Benzilates; Calcium Chloride; Carbachol; Cresols; Dose-Response Relation | 1999 |
[Effects of propiverine hydrochloride (propiverine) on isolated rat and dog urinary bladder].
Topics: Acetylcholine; Animals; Atropine; Benzilates; Butylamines; Dogs; Dose-Response Relationship, Drug; E | 1999 |
Effects of TAK-637, a tachykinin receptor antagonist, on the micturition reflex in guinea pigs.
Topics: Animals; Benzhydryl Compounds; Benzilates; Capsaicin; Cholinergic Antagonists; Cresols; Dilatation; | 2000 |
Possible site of action of TAK-637, a tachykinin NK(1) receptor antagonist, on the micturition reflex in guinea pigs.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Carbachol; Cresols; Denervation; Dose-Response | 2000 |
Effects of propiverine hydrochloride on the spontaneous contractions of isolated guinea-pig urinary bladder strip and rhythmic urinary bladder contractions of anesthetized dog.
Topics: Anesthesia; Animals; Benzilates; Blood Pressure; Dogs; Female; Flavoxate; Guinea Pigs; Heart Rate; I | 1992 |
Inhibitory effects of propiverine hydrochloride on the agonist-induced or spontaneous contractions of various isolated muscle preparations.
Topics: Animals; Benzilates; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smo | 1992 |
Anticholinergic properties of propiverine and its metabolites.
Topics: Animals; Benzilates; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Musc | 1990 |
[Effect of propiverine hydrochloride on the function of the bladder in dogs].
Topics: Animals; Benzilates; Dogs; Dose-Response Relationship, Drug; Female; Flavoxate; Male; Muscle Contrac | 1989 |
[Effects of propiverine hydrochloride and its metabolites on isolated guinea pig urinary bladder].
Topics: Acetylcholine; Animals; Benzilates; Calcium; Dose-Response Relationship, Drug; Female; Guinea Pigs; | 1989 |
[Effects of propiverine hydrochloride (P-4) and its metabolites on urinary bladder function in anesthetized rats].
Topics: Animals; Benzilates; Male; Muscle Contraction; Parasympatholytics; Rats; Rats, Inbred Strains; Urina | 1989 |
[The spasmolytic activity of propiverine and some of its structural analogs].
Topics: Adrenergic alpha-Antagonists; Animals; Arecoline; Barium; Barium Compounds; Benzilates; Chlorides; I | 1987 |