Page last updated: 2024-10-20

propionic acid and Mitochondrial Diseases

propionic acid has been researched along with Mitochondrial Diseases in 3 studies

propionic acid : A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group.

Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.

Research Excerpts

ExcerptRelevanceReference
"Propionic acid (PPA) is a ubiquitous short-chain fatty acid, which is a major fermentation product of the enteric microbiome."1.43Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines. ( Bennuri, SC; Chacko, J; Delhey, L; Frye, RE; Kahler, SG; MacFabe, DF; Melnyk, S; Rose, S; Slattery, JC; Tippett, M; Wynne, R, 2016)
"Acyl-carnitine panels were determined to be abnormal if three or more individual acyl-carnitine species were abnormal in the panel and these abnormalities were verified by repeated testing."1.39Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder. ( Frye, RE; Macfabe, DF; Melnyk, S, 2013)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frye, RE2
Rose, S1
Chacko, J1
Wynne, R1
Bennuri, SC1
Slattery, JC1
Tippett, M1
Delhey, L1
Melnyk, S2
Kahler, SG1
MacFabe, DF2
Schwab, MA1
Sauer, SW1
Okun, JG1
Nijtmans, LG1
Rodenburg, RJ1
van den Heuvel, LP1
Dröse, S1
Brandt, U1
Hoffmann, GF1
Ter Laak, H1
Kölker, S1
Smeitink, JA1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Chart Review to Evaluate the Safety and Efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on Subjects With Autism Spectrum Disorder (ASD)[NCT02758496]141 participants (Actual)Observational2016-04-30Completed
A Longitudinal Study on the Safety and Efficacy for Subjects With Autism Spectrum Disorder (ASD) Who Received Magnetic EEG/ECG-Guided Resonance Therapy (MeRT)[NCT02746445]11 participants (Actual)Observational2016-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for propionic acid and Mitochondrial Diseases

ArticleYear
Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines.
    Translational psychiatry, 2016, 10-25, Volume: 6, Issue:10

    Topics: Autism Spectrum Disorder; Case-Control Studies; Cell Line; Child; Gastrointestinal Microbiome; Human

2016
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.
    Translational psychiatry, 2013, Jan-22, Volume: 3

    Topics: Biomarkers; Carnitine; Child; Child Development Disorders, Pervasive; Cohort Studies; DNA, Mitochond

2013
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.
    Translational psychiatry, 2013, Jan-22, Volume: 3

    Topics: Biomarkers; Carnitine; Child; Child Development Disorders, Pervasive; Cohort Studies; DNA, Mitochond

2013
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.
    Translational psychiatry, 2013, Jan-22, Volume: 3

    Topics: Biomarkers; Carnitine; Child; Child Development Disorders, Pervasive; Cohort Studies; DNA, Mitochond

2013
Unique acyl-carnitine profiles are potential biomarkers for acquired mitochondrial disease in autism spectrum disorder.
    Translational psychiatry, 2013, Jan-22, Volume: 3

    Topics: Biomarkers; Carnitine; Child; Child Development Disorders, Pervasive; Cohort Studies; DNA, Mitochond

2013
Secondary mitochondrial dysfunction in propionic aciduria: a pathogenic role for endogenous mitochondrial toxins.
    The Biochemical journal, 2006, Aug-15, Volume: 398, Issue:1

    Topics: Acetyl Coenzyme A; Acyl Coenzyme A; Amino Acid Metabolism, Inborn Errors; Animals; Cattle; Energy Me

2006