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propionic acid and Innate Inflammatory Response

propionic acid has been researched along with Innate Inflammatory Response in 23 studies

propionic acid : A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group.

Research Excerpts

ExcerptRelevanceReference
"Fibrosis is a common complication of inflammatory bowel diseases (IBDs)."5.91The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis. ( Alston, LA; Flannigan, KL; Hirota, SA; Lee, JW; Mani, S; Nieves, KM; Ramay, H; Serra, A; Szczepanski, HE, 2023)
"Propionic acid (PPA) is a short-chain fatty acid produced endogenously by gut microbiota and found in foodstuffs and pharmaceutical products as an additive."5.72Acetyl-L-carnitine and/or liposomal co-enzyme Q10 prevent propionic acid-induced neurotoxicity by modulating oxidative tissue injury, inflammation, and ALDH1A1-RA-RARα signaling in rats. ( Abo-Hamad, A; Alhumaidan, S; Alhusaini, A; Almogren, R; Alsaif, S; Alsultan, E; Hasan, I; Hassanein, E; Mahmoud, A; Mattar, D; Sarawi, W, 2022)
"Treatment with pioglitazone, significantly attenuated the postnatal propionic acid-induced social impairment, repetitive behavior, hyperactivity, anxiety and low exploratory activity."5.51A selective peroxisome proliferator-activated receptor-γ agonist benefited propionic acid induced autism-like behavioral phenotypes in rats by attenuation of neuroinflammation and oxidative stress. ( Mirza, R; Sharma, B, 2019)
"We evaluated the in vivo pharmacological properties of AM803 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxy-pyridin-3-yl)-benzyl]-5-(5-methyl-pyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethyl-propionic acid, a selective five-lipoxygenase-activating protein (FLAP) inhibitor, using rat and mouse models of acute inflammation."3.76Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation. ( Baccei, CS; Bain, G; Broadhead, AR; Chapman, C; Correa, LD; Darlington, JV; Evans, JF; Hutchinson, JH; King, CD; Lee, C; Lorrain, DS; Prasit, P; Prodanovich, PP; Roppe, J; Santini, AM; Stearns, B; Stock, NS; Zunic, J, 2010)
"Fibrosis is a common complication of inflammatory bowel diseases (IBDs)."1.91The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis. ( Alston, LA; Flannigan, KL; Hirota, SA; Lee, JW; Mani, S; Nieves, KM; Ramay, H; Serra, A; Szczepanski, HE, 2023)
"Propionic acid (PPA) is a short-chain fatty acid produced endogenously by gut microbiota and found in foodstuffs and pharmaceutical products as an additive."1.72Acetyl-L-carnitine and/or liposomal co-enzyme Q10 prevent propionic acid-induced neurotoxicity by modulating oxidative tissue injury, inflammation, and ALDH1A1-RA-RARα signaling in rats. ( Abo-Hamad, A; Alhumaidan, S; Alhusaini, A; Almogren, R; Alsaif, S; Alsultan, E; Hasan, I; Hassanein, E; Mahmoud, A; Mattar, D; Sarawi, W, 2022)
"Treatment with pioglitazone, significantly attenuated the postnatal propionic acid-induced social impairment, repetitive behavior, hyperactivity, anxiety and low exploratory activity."1.51A selective peroxisome proliferator-activated receptor-γ agonist benefited propionic acid induced autism-like behavioral phenotypes in rats by attenuation of neuroinflammation and oxidative stress. ( Mirza, R; Sharma, B, 2019)
"Regressive autism is a devastating disorder affecting children between the ages of 15-30 months."1.40Model-based hypothesis of gut microbe populations and gut/brain barrier permeabilities in the development of regressive autism. ( Cook, D; Dhurjati, P; Downs, R; Perna, J; Vitelli, A, 2014)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's11 (47.83)24.3611
2020's12 (52.17)2.80

Authors

AuthorsStudies
Maruo, S1
Kuriyama, I1
Kuramochi, K1
Tsubaki, K1
Yoshida, H1
Mizushina, Y1
Erten, F1
Owumi, SE1
Adedara, IA1
Oyelere, AK1
Alhusaini, A1
Sarawi, W1
Mattar, D1
Abo-Hamad, A1
Almogren, R1
Alhumaidan, S1
Alsultan, E1
Alsaif, S1
Hasan, I1
Hassanein, E1
Mahmoud, A1
Zhao, Q1
Chen, T1
Ni, C1
Hu, Y1
Nan, Y1
Lin, W1
Liu, Y1
Zheng, F1
Shi, X1
Lin, Z2
Zhu, J1
Flannigan, KL1
Nieves, KM1
Szczepanski, HE1
Serra, A1
Lee, JW1
Alston, LA1
Ramay, H1
Mani, S1
Hirota, SA1
Azumi, J1
Shimada, Y1
Takeda, T1
Aso, H1
Nakamura, T1
Zhuang, H1
Ren, X1
Jiang, F1
Zhou, P1
Illikoud, N1
do Carmo, FLR1
Daniel, N1
Jan, G1
Gagnaire, V1
Shi, C1
Wan, Y1
He, A1
Wu, X1
Shen, X1
Zhu, X1
Yang, J1
Zhou, Y1
Aabed, K1
Bhat, RS1
Al-Dbass, A1
Moubayed, N1
Algahtani, N1
Merghani, NM1
Alanazi, A1
Zayed, N1
El-Ansary, A1
Tengeler, AC1
Gart, E1
Wiesmann, M1
Arnoldussen, IAC1
van Duyvenvoorde, W1
Hoogstad, M1
Dederen, PJ1
Verweij, V1
Geenen, B1
Kozicz, T1
Kleemann, R1
Morrison, MC1
Kiliaan, AJ1
Haase, S1
Mäurer, J1
Duscha, A1
Lee, DH1
Balogh, A1
Gold, R1
Müller, DN1
Haghikia, A1
Linker, RA1
Liu, FY1
Wen, J1
Hou, J1
Zhang, SQ1
Sun, CB1
Zhou, LC1
Yin, W1
Pang, WL1
Wang, C1
Ying, Y1
Han, SS1
Yan, JY1
Li, CX1
Yuan, JL1
Xing, HJ1
Yang, ZS1
Yisireyili, M1
Takeshita, K1
Saito, S1
Murohara, T1
Niwa, T1
Abdelli, LS1
Samsam, A1
Naser, SA1
Mirza, R1
Sharma, B1
Downs, R1
Perna, J1
Vitelli, A1
Cook, D1
Dhurjati, P1
Yajima, M1
Kimura, S1
Karaki, S1
Nio-Kobayashi, J1
Tsuruta, T1
Kuwahara, A1
Yajima, T1
Iwanaga, T1
Corrêa, RO1
Vieira, A1
Sernaglia, EM1
Lancellotti, M1
Vieira, AT1
Avila-Campos, MJ1
Rodrigues, HG1
Vinolo, MAR1
Nakajima, A1
Sato, H1
Oda, S1
Yokoi, T1
Lorrain, DS1
Bain, G1
Correa, LD1
Chapman, C1
Broadhead, AR1
Santini, AM1
Prodanovich, PP1
Darlington, JV1
Stock, NS1
Zunic, J1
King, CD1
Lee, C1
Baccei, CS1
Stearns, B1
Roppe, J1
Hutchinson, JH1
Prasit, P1
Evans, JF1
MacFabe, DF1
Cain, NE1
Boon, F1
Ossenkopp, KP1
Cain, DP1

Other Studies

23 other studies available for propionic acid and Innate Inflammatory Response

ArticleYear
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response.
    Bioorganic & medicinal chemistry, 2011, Oct-01, Volume: 19, Issue:19

    Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Cell Line, Tumor; DNA Polymerase beta; Enz

2011
Lycopene ameliorates propionic acid-induced autism spectrum disorders by inhibiting inflammation and oxidative stress in rats.
    Journal of food biochemistry, 2021, Volume: 45, Issue:10

    Topics: Animals; Autism Spectrum Disorder; Inflammation; Lycopene; Oxidative Stress; Propionates; Rats

2021
Indole-3-propionic acid mitigates chlorpyrifos-mediated neurotoxicity by modulating cholinergic and redox-regulatory systems, inflammatory stress, apoptotic responses and DNA damage in rats.
    Environmental toxicology and pharmacology, 2022, Volume: 89

    Topics: Animals; Apoptosis; Behavior, Animal; Chlorpyrifos; DNA Damage; Indoles; Inflammation; Insecticides;

2022
Acetyl-L-carnitine and/or liposomal co-enzyme Q10 prevent propionic acid-induced neurotoxicity by modulating oxidative tissue injury, inflammation, and ALDH1A1-RA-RARα signaling in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Acetylcarnitine; Animals; Antioxidants; Autism Spectrum Disorder; Inflammation; Neurotoxicity Syndro

2022
Indole-3-propionic Acid Attenuates HI-Related Blood-Brain Barrier Injury in Neonatal Rats by Modulating the PXR Signaling Pathway.
    ACS chemical neuroscience, 2022, 10-05, Volume: 13, Issue:19

    Topics: Animals; Animals, Newborn; Anti-Inflammatory Agents; Antioxidants; Blood-Brain Barrier; Brain Injuri

2022
The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis.
    Cellular and molecular gastroenterology and hepatology, 2023, Volume: 15, Issue:3

    Topics: Animals; Colitis, Ulcerative; Crohn Disease; Fibrosis; Indoles; Inflammation; Intestines; Mice; Preg

2023
The Organogermanium Compound 3-(Trihydroxygermyl) Propanoic Acid (THGP) Suppresses Inflammasome Activation Via Complexation with ATP.
    International journal of molecular sciences, 2022, Nov-01, Volume: 23, Issue:21

    Topics: Adenosine Triphosphate; Caspase 1; Cytokines; Diabetes Mellitus, Type 2; Humans; Inflammasomes; Infl

2022
Indole-3-propionic acid alleviates chondrocytes inflammation and osteoarthritis via the AhR/NF-κB axis.
    Molecular medicine (Cambridge, Mass.), 2023, 01-31, Volume: 29, Issue:1

    Topics: Animals; Chondrocytes; Inflammation; NF-kappa B; Osteoarthritis; Rats; Receptors, Aryl Hydrocarbon

2023
Development of innovative fermented products by exploiting the diversity of immunomodulatory properties and fermentative activity of lactic and propionic acid bacteria.
    Food research international (Ottawa, Ont.), 2023, Volume: 166

    Topics: Animals; Cultured Milk Products; Goats; Humans; Inflammation; Lactobacillus; Leukocytes, Mononuclear

2023
Urinary metabolites associate with the presence of diabetic kidney disease in type 2 diabetes and mediate the effect of inflammation on kidney complication.
    Acta diabetologica, 2023, Volume: 60, Issue:9

    Topics: Biomarkers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Inflammation; Interleukin-18;

2023
Bee pollen and propolis improve neuroinflammation and dysbiosis induced by propionic acid, a short chain fatty acid in a rodent model of autism.
    Lipids in health and disease, 2019, Nov-16, Volume: 18, Issue:1

    Topics: Animals; Autistic Disorder; Brain Chemistry; Cytokines; Disease Models, Animal; Dysbiosis; Inflammat

2019
Propionic acid and not caproic acid, attenuates nonalcoholic steatohepatitis and improves (cerebro) vascular functions in obese Ldlr
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:7

    Topics: Animals; Caproates; Cerebrovascular Disorders; Diet, Fat-Restricted; Diet, High-Fat; Inflammation; M

2020
Propionic Acid Rescues High-Fat Diet Enhanced Immunopathology in Autoimmunity
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Autoimmunity; Cell Proliferation; Cytokines; Diet, High-Fat; Encephalomyelitis, Autoimmune,

2021
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
    International immunopharmacology, 2021, Volume: 96

    Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal;

2021
Indole-3-propionic acid suppresses indoxyl sulfate-induced expression of fibrotic and inflammatory genes in proximal tubular cells.
    Nagoya journal of medical science, 2017, Volume: 79, Issue:4

    Topics: Animals; Blotting, Western; Cell Line; Chemokine CCL2; Cytochrome P-450 CYP1A1; Humans; Immunohistoc

2017
Propionic Acid Induces Gliosis and Neuro-inflammation through Modulation of PTEN/AKT Pathway in Autism Spectrum Disorder.
    Scientific reports, 2019, 06-19, Volume: 9, Issue:1

    Topics: Autism Spectrum Disorder; Biomarkers, Tumor; Butyric Acid; Cell Differentiation; Cell Proliferation;

2019
A selective peroxisome proliferator-activated receptor-γ agonist benefited propionic acid induced autism-like behavioral phenotypes in rats by attenuation of neuroinflammation and oxidative stress.
    Chemico-biological interactions, 2019, Sep-25, Volume: 311

    Topics: Animals; Anxiety; Autism Spectrum Disorder; Behavior, Animal; Brain; Disease Models, Animal; Explora

2019
Model-based hypothesis of gut microbe populations and gut/brain barrier permeabilities in the development of regressive autism.
    Medical hypotheses, 2014, Volume: 83, Issue:6

    Topics: Animals; Autistic Disorder; Bacteroides; Blood-Brain Barrier; Child, Preschool; Computer Simulation;

2014
Non-neuronal, but atropine-sensitive ileal contractile responses to short-chain fatty acids: age-dependent desensitization and restoration under inflammatory conditions in mice.
    Physiological reports, 2016, Volume: 4, Issue:7

    Topics: Acetic Acid; Acetylcholine; Acetylcholinesterase; Age Factors; Animals; Atropine; Choline O-Acetyltr

2016
Bacterial short-chain fatty acid metabolites modulate the inflammatory response against infectious bacteria.
    Cellular microbiology, 2017, Volume: 19, Issue:7

    Topics: Acetic Acid; Acrylamides; Aggregatibacter actinomycetemcomitans; Animals; Butyrates; Cytokines; Hist

2017
Fluoroquinolones and propionic acid derivatives induce inflammatory responses in vitro.
    Cell biology and toxicology, 2018, Volume: 34, Issue:1

    Topics: Allopurinol; Cell Line; Fluoroquinolones; Gene Expression Regulation; Humans; Inflammation; Levoflox

2018
Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation.
    European journal of pharmacology, 2010, Aug-25, Volume: 640, Issue:1-3

    Topics: 5-Lipoxygenase-Activating Proteins; Animals; Carrier Proteins; Chronic Disease; Cysteine; Disease Mo

2010
Effects of the enteric bacterial metabolic product propionic acid on object-directed behavior, social behavior, cognition, and neuroinflammation in adolescent rats: Relevance to autism spectrum disorder.
    Behavioural brain research, 2011, Feb-02, Volume: 217, Issue:1

    Topics: Animals; Astrocytes; Child; Child Development Disorders, Pervasive; Cognition; Disease Models, Anima

2011