propionic acid has been researched along with Crohn Disease in 3 studies
propionic acid : A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fibrosis is a common complication of inflammatory bowel diseases (IBDs)." | 5.91 | The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis. ( Alston, LA; Flannigan, KL; Hirota, SA; Lee, JW; Mani, S; Nieves, KM; Ramay, H; Serra, A; Szczepanski, HE, 2023) |
| "Fibrosis is a common complication of inflammatory bowel diseases (IBDs)." | 1.91 | The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis. ( Alston, LA; Flannigan, KL; Hirota, SA; Lee, JW; Mani, S; Nieves, KM; Ramay, H; Serra, A; Szczepanski, HE, 2023) |
| "Propionic acid (PA) is a bacterium-derived intestinal antimicrobial and immune modulator used widely in food production and agriculture." | 1.56 | Propionic Acid Promotes the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli. ( Boyd, J; Carpena, N; Connolly, JPR; Fitzgerald, E; Gerasimidis, K; Goldstone, RJ; Hansen, R; Hasson, C; Hold, GL; Hulme, HE; Johnson, SA; McConnachie, CC; McIntosh, A; Meikle, LM; Morrison, D; Ormsby, MJ; Roe, AJ; Smith, DGE; Walker, D; Wall, DM; Wessel, HM, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Flannigan, KL | 1 |
| Nieves, KM | 1 |
| Szczepanski, HE | 1 |
| Serra, A | 1 |
| Lee, JW | 1 |
| Alston, LA | 1 |
| Ramay, H | 1 |
| Mani, S | 1 |
| Hirota, SA | 1 |
| Ormsby, MJ | 1 |
| Johnson, SA | 1 |
| Carpena, N | 1 |
| Meikle, LM | 1 |
| Goldstone, RJ | 1 |
| McIntosh, A | 1 |
| Wessel, HM | 1 |
| Hulme, HE | 1 |
| McConnachie, CC | 1 |
| Connolly, JPR | 1 |
| Roe, AJ | 1 |
| Hasson, C | 1 |
| Boyd, J | 1 |
| Fitzgerald, E | 1 |
| Gerasimidis, K | 1 |
| Morrison, D | 1 |
| Hold, GL | 1 |
| Hansen, R | 1 |
| Walker, D | 1 |
| Smith, DGE | 1 |
| Wall, DM | 1 |
| Tjellström, B | 1 |
| Högberg, L | 1 |
| Stenhammar, L | 1 |
| Magnusson, KE | 1 |
| Midtvedt, T | 1 |
| Norin, E | 1 |
| Sundqvist, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Washed Microbiota Transplantation Combining Exclusive Enteral Nutrition Contribute to Nutritional Improvement of Patients With Crohns' Disease[NCT02897661] | 30 participants (Anticipated) | Interventional | 2016-08-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 other studies available for propionic acid and Crohn Disease
| Article | Year |
|---|---|
The Pregnane X Receptor and Indole-3-Propionic Acid Shape the Intestinal Mesenchyme to Restrain Inflammation and Fibrosis.
Topics: Animals; Colitis, Ulcerative; Crohn Disease; Fibrosis; Indoles; Inflammation; Intestines; Mice; Preg | 2023 |
Propionic Acid Promotes the Virulent Phenotype of Crohn's Disease-Associated Adherent-Invasive Escherichia coli.
Topics: Animals; Bacterial Adhesion; Crohn Disease; Escherichia coli; Escherichia coli Infections; Humans; M | 2020 |
Effect of exclusive enteral nutrition on gut microflora function in children with Crohn's disease.
Topics: Acetic Acid; Adolescent; Anus Diseases; Butyric Acid; Case-Control Studies; Child; Colitis; Crohn Di | 2012 |