Page last updated: 2024-10-20

propionic acid and Cognitive Dysfunction

propionic acid has been researched along with Cognitive Dysfunction in 3 studies

propionic acid : A short-chain saturated fatty acid comprising ethane attached to the carbon of a carboxy group.

Cognitive Dysfunction: Diminished or impaired mental and/or intellectual function.

Research Excerpts

ExcerptRelevanceReference
"Our findings show that intracerebroventricular injection of streptozotocin accelerated cognitive dysfunction associated with increasing levels of glycogen synthase kinase 3 beta (GSK3β) activity, tau protein phosphorylation at the T231 site (pT231), amyloid-β (Aβ) deposition, amyloid-β protein precursor (AβPP), β-site AβPP-cleaving enzyme (BACE1), gliosis, fecal propionic acid (PPA) levels and cognition-related neuronal loss and decreasing postsynaptic density protein 95 (PSD95) levels in 3 × Tg-AD mice."8.02Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer's disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis. ( Chen, JL; Chen, YH; Chieu, MW; Hsieh-Li, HM; Hsu, CC; Huang, HJ; Ke, YY; Liao, JF; Tsai, YC, 2021)
"Our findings show that intracerebroventricular injection of streptozotocin accelerated cognitive dysfunction associated with increasing levels of glycogen synthase kinase 3 beta (GSK3β) activity, tau protein phosphorylation at the T231 site (pT231), amyloid-β (Aβ) deposition, amyloid-β protein precursor (AβPP), β-site AβPP-cleaving enzyme (BACE1), gliosis, fecal propionic acid (PPA) levels and cognition-related neuronal loss and decreasing postsynaptic density protein 95 (PSD95) levels in 3 × Tg-AD mice."4.02Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer's disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis. ( Chen, JL; Chen, YH; Chieu, MW; Hsieh-Li, HM; Hsu, CC; Huang, HJ; Ke, YY; Liao, JF; Tsai, YC, 2021)
"Gut microbial dysbiosis is associated with neurological diseases; however, the mechanisms by which the microbiota regulates postoperative gastrointestinal and cognitive function are incompletely understood."1.91Surgery-induced gut microbial dysbiosis promotes cognitive impairment via regulation of intestinal function and the metabolite palmitic amide. ( Chen, L; Liu, X; Meng, Q; Pan, C; Wang, X; Xu, L; Xu, N; Zhang, H; Zhang, L; Zhang, ZY, 2023)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's3 (100.00)2.80

Authors

AuthorsStudies
Huang, HJ1
Chen, JL1
Liao, JF1
Chen, YH1
Chieu, MW1
Ke, YY1
Hsu, CC1
Tsai, YC1
Hsieh-Li, HM1
Neuffer, J1
González-Domínguez, R1
Lefèvre-Arbogast, S1
Low, DY1
Driollet, B1
Helmer, C1
Du Preez, A1
de Lucia, C1
Ruigrok, SR1
Altendorfer, B1
Aigner, L1
Lucassen, PJ1
Korosi, A1
Thuret, S1
Manach, C1
Pallàs, M1
Urpi-Sardà, M1
Sánchez-Pla, A1
Andres-Lacueva, C1
Samieri, C1
Pan, C1
Zhang, H1
Zhang, L1
Chen, L1
Xu, L1
Xu, N1
Liu, X1
Meng, Q1
Wang, X1
Zhang, ZY1

Other Studies

3 other studies available for propionic acid and Cognitive Dysfunction

ArticleYear
Lactobacillus plantarum PS128 prevents cognitive dysfunction in Alzheimer's disease mice by modulating propionic acid levels, glycogen synthase kinase 3 beta activity, and gliosis.
    BMC complementary medicine and therapies, 2021, Oct-09, Volume: 21, Issue:1

    Topics: Alzheimer Disease; Animals; Cognitive Dysfunction; Disease Models, Animal; Gliosis; Glycogen Synthas

2021
Exploration of the Gut-Brain Axis through Metabolomics Identifies Serum Propionic Acid Associated with Higher Cognitive Decline in Older Persons.
    Nutrients, 2022, Nov-05, Volume: 14, Issue:21

    Topics: Aged; Aged, 80 and over; Brain-Gut Axis; Case-Control Studies; Cognitive Dysfunction; Humans; Metabo

2022
Surgery-induced gut microbial dysbiosis promotes cognitive impairment via regulation of intestinal function and the metabolite palmitic amide.
    Microbiome, 2023, 11-08, Volume: 11, Issue:1

    Topics: Animals; Cognitive Dysfunction; Dexamethasone; Dysbiosis; Gastrointestinal Microbiome; Indoles; Mice

2023