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propidium and Nerve Degeneration

propidium has been researched along with Nerve Degeneration in 27 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
" Dihydroergocryptine antagonized both the neuronal death produced by acute exposure to a toxic glutamate concentration as well as the normal age-dependent degeneration in culture."1.29Protection by dihydroergocryptine of glutamate-induced neurotoxicity. ( Aleppo, G; Canonico, PL; Favit, A; Scapagnini, U; Sortino, MA, 1993)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (33.33)18.2507
2000's16 (59.26)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Eles, JR1
Vazquez, AL1
Kozai, TDY1
Cui, XT1
Horn, AP1
Frozza, RL1
Grudzinski, PB1
Gerhardt, D1
Hoppe, JB1
Bruno, AN1
Chagastelles, P1
Nardi, NB1
Lenz, G1
Salbego, C1
Montero Domínguez, M1
González, B1
Zimmer, J4
de Calignon, A1
Spires-Jones, TL1
Pitstick, R1
Carlson, GA1
Hyman, BT1
Ebrahimi, F1
Hezel, M1
Koch, M1
Ghadban, C1
Korf, HW1
Dehghani, F1
Brana, C1
Benham, C1
Sundstrom, L1
Eyüpoglu, IY1
Savaskan, NE1
Bräuer, AU1
Nitsch, R1
Heimrich, B1
Ikegami, K1
Koike, T1
Adembri, C1
Bechi, A1
Meli, E1
Gramigni, E1
Venturi, L1
Moroni, F1
De Gaudio, AR1
Pellegrini-Giampietro, DE1
Belmadani, A1
Kumar, S1
Schipma, M1
Collins, MA1
Neafsey, EJ1
Noraberg, J4
Elsisi, NS1
Darling-Reed, S1
Lee, EY1
Oriaku, ET1
Soliman, KF1
de Pina-Benabou, MH1
Szostak, V1
Kyrozis, A1
Rempe, D1
Uziel, D1
Urban-Maldonado, M1
Benabou, S1
Spray, DC1
Federoff, HJ1
Stanton, PK1
Rozental, R1
Lapanantasin, S1
Chongthammakun, S1
Floyd, CL1
Berman, RF1
Bottlang, M1
Sommers, MB1
Lusardi, TA1
Miesch, JJ1
Simon, RP1
Xiong, ZG1
Choi, JS1
Kim, SJ1
Shin, JA1
Lee, KE1
Park, EM1
Okada, M2
Sakaguchi, T2
Kawasaki, K2
Wilde, GJ1
Sundström, LE1
Iannotti, F1
Favit, A1
Sortino, MA1
Aleppo, G1
Scapagnini, U1
Canonico, PL1
Keilhoff, G1
Wolf, G1
Rossi, F1
Borsello, T1
Vaudano, E1
Strata, P1
Kuno, M1
Gramsbergen, JB1
Fonnum, F1
Rundén, E1
Seglen, PO1
Haug, FM1
Ottersen, OP1
Wieloch, T1
Shamloo, M1
Laake, JH1
Kristensen, BW1
Kim, EJ1
Lee, JE1
Kwon, KJ1
Lee, SH1
Moon, CH1
Baik, EJ1
Bonde, C1

Other Studies

27 other studies available for propidium and Nerve Degeneration

ArticleYear
In vivo imaging of neuronal calcium during electrode implantation: Spatial and temporal mapping of damage and recovery.
    Biomaterials, 2018, Volume: 174

    Topics: Animals; Brain-Computer Interfaces; Calcium; Calcium Signaling; Electric Impedance; Electrodes, Impl

2018
Conditioned medium from mesenchymal stem cells induces cell death in organotypic cultures of rat hippocampus and aggravates lesion in a model of oxygen and glucose deprivation.
    Neuroscience research, 2009, Volume: 63, Issue:1

    Topics: Animals; Cell Death; Cells, Cultured; Culture Media, Conditioned; Excitatory Amino Acid Antagonists;

2009
Neuroprotective effects of the anti-inflammatory compound triflusal on ischemia-like neurodegeneration in mouse hippocampal slice cultures occur independent of microglia.
    Experimental neurology, 2009, Volume: 218, Issue:1

    Topics: Analysis of Variance; Animals; Animals, Newborn; Cell Count; Cell Death; Cell Movement; Cell Prolife

2009
Tangle-bearing neurons survive despite disruption of membrane integrity in a mouse model of tauopathy.
    Journal of neuropathology and experimental neurology, 2009, Volume: 68, Issue:7

    Topics: Animals; Brain; Caspases; Cell Death; Cell Membrane; Cell Survival; Disease Models, Animal; Fluoresc

2009
Analyses of neuronal damage in excitotoxically lesioned organotypic hippocampal slice cultures.
    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 2010, Aug-20, Volume: 192, Issue:4

    Topics: Animals; CA1 Region, Hippocampal; Coloring Agents; Dentate Gyrus; Excitatory Amino Acid Agonists; Mi

2010
A method for characterising cell death in vitro by combining propidium iodide staining with immunohistochemistry.
    Brain research. Brain research protocols, 2002, Volume: 10, Issue:2

    Topics: Animals; Animals, Newborn; Cell Death; Cells, Cultured; Hippocampus; Hypoxia-Ischemia, Brain; Immuno

2002
Identification of neuronal cell death in a model of degeneration in the hippocampus.
    Brain research. Brain research protocols, 2003, Volume: 11, Issue:1

    Topics: Animals; Animals, Newborn; Axons; Biomarkers; Cell Death; Cell Line; Dendrites; Disease Models, Anim

2003
Non-apoptotic neurite degeneration in apoptotic neuronal death: pivotal role of mitochondrial function in neurites.
    Neuroscience, 2003, Volume: 122, Issue:3

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Antineoplastic Agents, Phytogenic; Carbonyl Cyani

2003
Erythropoietin attenuates post-traumatic injury in organotypic hippocampal slices.
    Journal of neurotrauma, 2004, Volume: 21, Issue:8

    Topics: Animals; Animals, Newborn; Brain Injuries; Dizocilpine Maleate; Down-Regulation; Erythropoietin; Exc

2004
Inhibition of amyloid-beta-induced neurotoxicity and apoptosis by moderate ethanol preconditioning.
    Neuroreport, 2004, Sep-15, Volume: 15, Issue:13

    Topics: Amyloid beta-Peptides; Animals; Animals, Newborn; Apoptosis; Benzimidazoles; Central Nervous System

2004
Organotypic brain slice cultures: an efficient and reliable method for neurotoxicological screening and mechanistic studies.
    Alternatives to laboratory animals : ATLA, 2004, Volume: 32, Issue:4

    Topics: Animal Testing Alternatives; Animals; Brain; Cell Death; Glutamic Acid; Hippocampus; Kainic Acid; Mi

2004
Ibuprofen and apigenin induce apoptosis and cell cycle arrest in activated microglia.
    Neuroscience letters, 2005, Feb-28, Volume: 375, Issue:2

    Topics: Animals; Annexin A5; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Apigenin; Ap

2005
Blockade of gap junctions in vivo provides neuroprotection after perinatal global ischemia.
    Stroke, 2005, Volume: 36, Issue:10

    Topics: Animals; Anti-Ulcer Agents; Apoptosis; Brain; Carbenoxolone; Caspase 3; Caspases; Cell Communication

2005
Effects of 17beta-estradiol on intracellular calcium changes and neuronal survival after mechanical strain injury in neuronal-glial cultures.
    Synapse (New York, N.Y.), 2006, Volume: 60, Issue:5

    Topics: Animals; Brain; Brain Injuries; Calcium; Calcium Signaling; Cell Survival; Cells, Cultured; Cocultur

2006
Modeling neural injury in organotypic cultures by application of inertia-driven shear strain.
    Journal of neurotrauma, 2007, Volume: 24, Issue:6

    Topics: Animals; Animals, Newborn; Biomechanical Phenomena; Brain Injuries; Cell Death; Coloring Agents; Hip

2007
Effects of estrogen on temporal expressions of IL-1beta and IL-1ra in rat organotypic hippocampal slices exposed to oxygen-glucose deprivation.
    Neuroscience letters, 2008, Jun-20, Volume: 438, Issue:2

    Topics: Animals; Cell Death; Cell Survival; Cytoprotection; Down-Regulation; Encephalitis; Estradiol; Estrog

2008
Correlation between anti-ubiquitin immunoreactivity and region-specific neuronal death in N-methyl-D-aspartate-treated rat hippocampal organotypic cultures.
    Neuroscience research, 1995, Volume: 22, Issue:4

    Topics: Animals; Axons; Electrophysiology; Excitatory Amino Acid Agonists; Hippocampus; Immunoblotting; Immu

1995
Propidium iodide in vivo: an early marker of neuronal damage in rat hippocampus.
    Neuroscience letters, 1994, Oct-24, Volume: 180, Issue:2

    Topics: Animals; Biological Transport; Cell Death; Chromatin; Fluorescent Dyes; Hippocampus; Injections, Int

1994
Protection by dihydroergocryptine of glutamate-induced neurotoxicity.
    Pharmacology & toxicology, 1993, Volume: 73, Issue:4

    Topics: Aging; Animals; Cell Survival; Cells, Cultured; Cerebellar Cortex; Dihydroergotoxine; Dose-Response

1993
Comparison of double fluorescence staining and LDH-test for monitoring cell viability in vitro.
    Neuroreport, 1993, Nov-18, Volume: 5, Issue:2

    Topics: Animals; Biomarkers; Cell Survival; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Cy

1993
Regressive modifications of climbing fibres following Purkinje cell degeneration in the cerebellar cortex of the adult rat.
    Neuroscience, 1993, Volume: 53, Issue:3

    Topics: Animals; Cerebellar Cortex; Immunohistochemistry; Kainic Acid; Nerve Degeneration; Nerve Fibers; Oli

1993
Dual mode of N-methyl-D-aspartate-induced neuronal death in hippocampal slice cultures in relation to N-methyl-D-aspartate receptor properties.
    Neuroscience, 1997, Volume: 76, Issue:2

    Topics: Animals; Cell Death; Cell Membrane; Electrophysiology; Excitatory Amino Acid Agonists; Hippocampus;

1997
Trimethyltin (TMT) neurotoxicity in organotypic rat hippocampal slice cultures.
    Brain research, 1998, Feb-09, Volume: 783, Issue:2

    Topics: Animals; Cobalt; Coloring Agents; Glutamic Acid; Hippocampus; Immunohistochemistry; L-Lactate Dehydr

1998
Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1998, Sep-15, Volume: 18, Issue:18

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Apoptosis; Benzylamines; Calci

1998
Markers for neuronal degeneration in organotypic slice cultures.
    Brain research. Brain research protocols, 1999, Volume: 3, Issue:3

    Topics: Animals; Animals, Newborn; Biomarkers; Calcium Channels; Cells, Cultured; Cerebral Cortex; Cobalt; C

1999
Differential roles of cyclooxygenase isoforms after kainic acid-induced prostaglandin E(2) production and neurodegeneration in cortical and hippocampal cell cultures.
    Brain research, 2001, Jul-20, Volume: 908, Issue:1

    Topics: Animals; Astrocytes; Bisbenzimidazole; Cells, Cultured; Cerebral Cortex; Coloring Agents; Cyclooxyge

2001
Nuclear shrinkage and other markers of neuronal cell death after oxygen-glucose deprivation in rat hippocampal slice cultures.
    Neuroscience letters, 2002, Jul-12, Volume: 327, Issue:1

    Topics: Animals; Benzimidazoles; Cell Death; Cell Hypoxia; Cell Nucleus; Coloring Agents; Fluorescent Dyes;

2002