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propidium and Neoplasms

propidium has been researched along with Neoplasms in 38 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Malignant peripheral nerve sheath tumors (MPNSTs) are aggressive sarcomas that typically carry a dismal prognosis."1.72Photonic hyperthermia of malignant peripheral nerve sheath tumors at the third near-infrared biowindow. ( Chang, M; Chen, Y; Feng, W; Gu, Y; Li, Q; Li, Y; Wang, W; Wang, Z; Wei, C, 2022)
"Apoptosis in cell cultures and whole tumors was detected by propidium iodide (PI) and TUNEL staining, respectively."1.72Neospora caninum inhibits tumor development by activating the immune response and destroying tumor cells in a B16F10 melanoma model. ( He, K; He, L; Jia, Y; Li, X; Liu, H; Lv, C; Qi, M; Qian, W; Wang, T; Wei, Z; Yan, W; Yu, F; Zhang, M; Zhao, L, 2022)
"Gambogic acid (GA) is a natural product with potent apoptotic activity."1.35Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells. ( Gu, H; Guo, Q; Ling, H; Liu, W; Lu, N; Mu, R; Qi, Q; Rao, S; Ren, FL; Wang, J; Wang, X; Yang, Y; You, Q; Zhao, J, 2008)
"We analyzed 24 non-small-cell lung cancer (NSCLC) samples by semi-quantitative RT-PCR."1.33Differential expression of survivin-2B and survivin-DeltaEx3 is inversely associated with disease relapse and patient survival in non-small-cell lung cancer (NSCLC). ( Bundy, BN; Li, F; Ling, X; Ramnath, N; Slocum, HK; Tan, D; Yang, J; Yang, L; Younis, T; Zhou, M, 2005)
"With ranges of SSRIs cytotoxicity on cancer cells defined, limits in their possible applicability in cancer therapy is discussed."1.33Cytotoxicity of different selective serotonin reuptake inhibitors (SSRIs) against cancer cells. ( Conti, M; Frasnelli, M; Rosetti, M; Tesei, A; Zoli, W, 2006)
"Because survival for patients with oral cancer has not improved over the past 25 years, new approaches for treatment are needed."1.32Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer. ( Bekele, BN; Bucana, CD; Doan, DD; Fidler, IJ; Greenberg, JS; Holsinger, FC; Jasser, SA; Myers, JN; Schiff, BA; Swan, EA; Younes, MN, 2003)
"Growth of subcutaneous 9L rat tumors transduced ex vivo with TK-GFP gene was prevented when ganciclovir (GCV) treatment was initiated immediately after tumor inoculation."1.32TK-GFP fusion gene virus vectors as tools for studying the features of HSV-TK/ganciclovir cancer gene therapy in vivo. ( Hakkarainen, T; Loimas, S; Parkkinen, J; Pasanen, T; Tenhunen, A; Timonen, P; Wahlfors, J, 2003)
"Ad-mda7-transduced cancer or normal cell lines were assayed for cell proliferation (tritiated thymidine incorporation assay, Alamar blue assay, and trypan-blue exclusion assay), apoptosis (TUNEL, and Annexin V staining visualized by fluorescent microscopy or FACs analysis), and cell cycle regulation (Propidium Iodide staining and FACs analysis)."1.31Melanoma differentiation associated gene-7 (mda-7): a novel anti-tumor gene for cancer gene therapy. ( Chada, S; Fanger, G; Fisher, PB; Hindi, M; Kourouma, F; Liao, J; Mhashilkar, AM; Onishi, E; Ramesh, R; Roth, JA; Saeki, T; Schrock, RD; Sieger, K; Snary, D; Stewart, L; Takh, O; Vedvick, TS; Watson, GJ; Zou-Yang, XH, 2001)
"Solid tumors were dissociated by a combined mechanical/ enzymatic method."1.29One-tube triple staining method for flow cytometric analysis of DNA ploidy and phenotypic heterogeneity of human solid tumors using single laser excitation. ( Abeln, EC; Bonsing, BA; Cornelisse, CJ; Corver, WE; Fleuren, GJ; Vlak-Theil, PM, 1996)
" Reproducible dose-response curves were obtained for 6 drugs tested."1.27The PIT method: an automated in vitro technique for drug toxicity testing. ( Lelieveld, P; van Lambalgen, R, 1987)

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.53)18.7374
1990's6 (15.79)18.2507
2000's18 (47.37)29.6817
2010's8 (21.05)24.3611
2020's2 (5.26)2.80

Authors

AuthorsStudies
Gu, Y1
Wang, Z1
Wei, C1
Li, Y1
Feng, W1
Wang, W1
Chang, M1
Chen, Y2
Li, Q1
Li, X1
Qi, M1
He, K1
Liu, H1
Yan, W2
Zhao, L1
Jia, Y1
He, L1
Lv, C1
Zhang, M1
Wei, Z1
Wang, T1
Yu, F1
Qian, W1
Kang, B1
Austin, LA1
El-Sayed, MA1
Gu, H1
Wang, X1
Rao, S1
Wang, J1
Zhao, J1
Ren, FL1
Mu, R1
Yang, Y1
Qi, Q1
Liu, W1
Lu, N1
Ling, H1
You, Q1
Guo, Q1
Ozdemir, O1
Chopinet, L1
Wasungu, L1
Rols, MP1
Ongaro, A1
Pellati, A1
Caruso, A1
Battista, M1
De Terlizzi, F1
De Mattei, M1
Fini, M1
Istivan, TS1
Pirogova, E1
Gan, E1
Almansour, NM1
Coloe, PJ1
Cosic, I1
Kim, SK1
Foote, MB1
Huang, L1
Khonkarn, R1
Mankhetkorn, S1
Talelli, M1
Hennink, WE1
Okonogi, S1
Cheng, H1
Hong, B1
Zhou, L1
Allen, JE1
Tai, G1
Humphreys, R1
Dicker, DT1
Liu, YY1
El-Deiry, WS1
Itoh, M1
Kitano, T1
Watanabe, M1
Kondo, T1
Yabu, T1
Taguchi, Y1
Iwai, K1
Tashima, M1
Uchiyama, T1
Okazaki, T1
Okumura, T1
Shimada, Y1
Imamura, M1
Yasumoto, S1
Holsinger, FC1
Doan, DD1
Jasser, SA1
Swan, EA1
Greenberg, JS1
Schiff, BA1
Bekele, BN1
Younes, MN1
Bucana, CD1
Fidler, IJ1
Myers, JN1
Pasanen, T1
Hakkarainen, T1
Timonen, P1
Parkkinen, J1
Tenhunen, A1
Loimas, S1
Wahlfors, J1
Wu, X1
Hui, KM1
Dertinger, SD1
Camphausen, K1
Macgregor, JT1
Bishop, ME1
Torous, DK1
Avlasevich, S1
Cairns, S1
Tometsko, CR1
Menard, C1
Muanza, T1
Miller, RK1
Cederbrant, K1
Sandelin, K1
Pontén, I1
Bolcsfoldi, G1
Bohnenkamp, HR1
Burchell, JM1
Taylor-Papadimitriou, J1
Noll, T1
Sugawara, S1
Sasaki, S1
Ogawa, Y1
Hosono, M1
Nitta, K1
Coffey, JC1
Wang, JH1
Smith, MJ1
Laing, A1
Bouchier-Hayes, D1
Cotter, TG1
Redmond, HP1
Ling, X1
Yang, J1
Tan, D1
Ramnath, N1
Younis, T1
Bundy, BN1
Slocum, HK1
Yang, L1
Zhou, M1
Li, F1
Salvioli, S1
Bonafé, M1
Barbi, C1
Storci, G1
Trapassi, C1
Tocco, F1
Gravina, S1
Rossi, M1
Tiberi, L1
Mondello, C1
Monti, D1
Franceschi, C1
Osaki, T1
Takagi, S1
Hoshino, Y1
Okumura, M1
Fujinaga, T1
Rosetti, M1
Frasnelli, M1
Tesei, A1
Zoli, W1
Conti, M1
Ogawa, M1
Nakai, S1
Deguchi, A1
Nonomura, T1
Masaki, T1
Uchida, N1
Yoshiji, H1
Kuriyama, S1
Wilhelm, C1
Fortin, JP1
Gazeau, F1
Deitch, AD1
Law, H1
deVere White, R1
Cunningham, RE2
Corver, WE1
Bonsing, BA1
Abeln, EC1
Vlak-Theil, PM1
Cornelisse, CJ1
Fleuren, GJ1
Hultdin, M1
Grönlund, E1
Norrback, K1
Eriksson-Lindström, E1
Just, T1
Roos, G1
Leers, MP1
Schutte, B1
Theunissen, PH1
Ramaekers, FC1
Nap, M1
Wen, J1
Krishan, A1
Thomas, RA1
Mhashilkar, AM1
Schrock, RD1
Hindi, M1
Liao, J1
Sieger, K1
Kourouma, F1
Zou-Yang, XH1
Onishi, E1
Takh, O1
Vedvick, TS1
Fanger, G1
Stewart, L1
Watson, GJ1
Snary, D1
Fisher, PB1
Saeki, T1
Roth, JA1
Ramesh, R1
Chada, S1
Almasri, NM1
Iturraspe, JA1
Benson, NA1
Chen, MG1
Braylan, RC1
Sasaki, K1
Tanaka, K1
Murakami, T1
Ogino, T1
Kawasaki, M1
Takahashi, M1
Tenjin, T1
van Lambalgen, R1
Lelieveld, P1
Pavlik, EJ1
Flanigan, RC1
van Nagell, JR1
Hanson, MB1
Donaldson, ES1
Keaton, K1
Doss, B1
Bartmas, J1
Kenady, DE1

Other Studies

38 other studies available for propidium and Neoplasms

ArticleYear
Photonic hyperthermia of malignant peripheral nerve sheath tumors at the third near-infrared biowindow.
    eLife, 2022, 09-16, Volume: 11

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; China; Humans; Hyperthermia, Induced; Mice; Neopla

2022
Neospora caninum inhibits tumor development by activating the immune response and destroying tumor cells in a B16F10 melanoma model.
    Parasites & vectors, 2022, Sep-23, Volume: 15, Issue:1

    Topics: Animals; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Cytokines; Eosine Yellowish-(YS); Hematoxylin; I

2022
Observing real-time molecular event dynamics of apoptosis in living cancer cells using nuclear-targeted plasmonically enhanced Raman nanoprobes.
    ACS nano, 2014, May-27, Volume: 8, Issue:5

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Nucleus; DNA; DNA Fragmentation; Gold; Huma

2014
Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells.
    Molecular cancer therapeutics, 2008, Volume: 7, Issue:10

    Topics: Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Cell Proliferation; Down-Regulation; Humans;

2008
Flow cytometric mast cell-mediated cytotoxicity assay: a three-color flow cytometric approach using monoclonal antibody staining with annexin V/propidium iodide co-labeling to assess human mast cell-mediated cytotoxicity by fluorosphere-adjusted counts.
    Journal of immunological methods, 2011, Feb-28, Volume: 365, Issue:1-2

    Topics: Annexin A5; Antibodies, Monoclonal; Cell Line, Tumor; Chromium Radioisotopes; Cytotoxicity Tests, Im

2011
First explanations for differences in electrotransfection efficiency in vitro and in vivo using spheroid model.
    International journal of pharmaceutics, 2012, Feb-14, Volume: 423, Issue:1

    Topics: Cell Culture Techniques; Cell Membrane; Cell Proliferation; Cell Survival; DNA; Electrochemotherapy;

2012
Identification of in vitro electropermeabilization equivalent pulse protocols.
    Technology in cancer research & treatment, 2011, Volume: 10, Issue:5

    Topics: Cell Line; Cell Membrane Permeability; Cell Survival; Electrochemotherapy; Electroporation; Fluoresc

2011
Biological effects of a de novo designed myxoma virus peptide analogue: evaluation of cytotoxicity on tumor cells.
    PloS one, 2011, Volume: 6, Issue:9

    Topics: Animals; Annexin A5; Apoptosis; Cell Death; Cell Line, Tumor; Cell Survival; Computational Biology;

2011
The targeted intracellular delivery of cytochrome C protein to tumors using lipid-apolipoprotein nanoparticles.
    Biomaterials, 2012, Volume: 33, Issue:15

    Topics: Amino Acid Sequence; Animals; Annexin A5; Apolipoproteins; Apoptosis; Caspase 3; Cell Line, Tumor; C

2012
Cytostatic effect of xanthone-loaded mPEG-b-p(HPMAm-Lac2) micelles towards doxorubicin sensitive and resistant cancer cells.
    Colloids and surfaces. B, Biointerfaces, 2012, Jun-01, Volume: 94

    Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cytostatic Agents; Doxorubicin; Drug Carriers; Drug Comp

2012
Mitomycin C potentiates TRAIL-induced apoptosis through p53-independent upregulation of death receptors: evidence for the role of c-Jun N-terminal kinase activation.
    Cell cycle (Georgetown, Tex.), 2012, Sep-01, Volume: 11, Issue:17

    Topics: Analysis of Variance; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis;

2012
Possible role of ceramide as an indicator of chemoresistance: decrease of the ceramide content via activation of glucosylceramide synthase and sphingomyelin synthase in chemoresistant leukemia.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Apoptosis; Cell Line; Cell Separation; Ceramides; DNA, Complementary

2003
Neurotrophin receptor p75(NTR) characterizes human esophageal keratinocyte stem cells in vitro.
    Oncogene, 2003, Jun-26, Volume: 22, Issue:26

    Topics: Blotting, Western; Carcinoma, Squamous Cell; Cell Adhesion; Cell Cycle; Cell Division; Cell Membrane

2003
Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-01, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Death; Cell Line, Tum

2003
TK-GFP fusion gene virus vectors as tools for studying the features of HSV-TK/ganciclovir cancer gene therapy in vivo.
    International journal of molecular medicine, 2003, Volume: 12, Issue:4

    Topics: Animals; Antiviral Agents; Cell Line, Tumor; Flow Cytometry; Ganciclovir; Gene Transfer Techniques;

2003
Induction of potent TRAIL-mediated tumoricidal activity by hFLEX/Furin/TRAIL recombinant DNA construct.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2004, Volume: 9, Issue:5

    Topics: Animals; Annexin A5; Antibodies; Apoptosis; Apoptosis Regulatory Proteins; Carcinoma; Cell Line, Tum

2004
Three-color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood.
    Environmental and molecular mutagenesis, 2004, Volume: 44, Issue:5

    Topics: Adult; Animals; Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Antimetabolites, Antineoplast

2004
Apoptosis of monocytes and the influence on yield of monocyte-derived dendritic cells.
    Journal of immunological methods, 2004, Volume: 294, Issue:1-2

    Topics: Annexin A5; Apoptosis; Cancer Vaccines; Cell Differentiation; Cell Separation; Cells, Cultured; Cyto

2004
[Catfish (Silurus asotus) lectin enhances the cytotoxic effects of doxorubicin].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2005, Volume: 125, Issue:3

    Topics: Animals; Annexin A5; Antibiotics, Antineoplastic; Apoptosis; Cell Membrane; Cell Membrane Permeabili

2005
Phosphoinositide 3-kinase accelerates postoperative tumor growth by inhibiting apoptosis and enhancing resistance to chemotherapy-induced apoptosis. Novel role for an old enemy.
    The Journal of biological chemistry, 2005, Jun-03, Volume: 280, Issue:22

    Topics: Animals; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Li

2005
Differential expression of survivin-2B and survivin-DeltaEx3 is inversely associated with disease relapse and patient survival in non-small-cell lung cancer (NSCLC).
    Lung cancer (Amsterdam, Netherlands), 2005, Volume: 49, Issue:3

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Clon

2005
p53 codon 72 alleles influence the response to anticancer drugs in cells from aged people by regulating the cell cycle inhibitor p21WAF1.
    Cell cycle (Georgetown, Tex.), 2005, Volume: 4, Issue:9

    Topics: Adult; Age Factors; Aged, 80 and over; Aging; Alleles; Antineoplastic Agents; Apoptosis; Arginine; b

2005
Intracellular localization and concentration as well as photodynamic effects of benzoporphyrin derivative monoacid ring A in four types of rodent tumor cells.
    Cancer letters, 2006, Nov-18, Volume: 243, Issue:2

    Topics: Animals; Apoptosis; Biological Transport; Cell Line, Tumor; Cell Survival; Dose-Response Relationshi

2006
Cytotoxicity of different selective serotonin reuptake inhibitors (SSRIs) against cancer cells.
    Journal of experimental therapeutics & oncology, 2006, Volume: 6, Issue:1

    Topics: Animals; Antidepressive Agents; Benzimidazoles; Biological Transport; Cell Line, Tumor; Cyclohexanol

2006
Vitamins K2, K3 and K5 exert antitumor effects on established colorectal cancer in mice by inducing apoptotic death of tumor cells.
    International journal of oncology, 2007, Volume: 31, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colorectal Neoplasms; Dose-Response Rel

2007
Tumour cell toxicity of intracellular hyperthermia mediated by magnetic nanoparticles.
    Journal of nanoscience and nanotechnology, 2007, Volume: 7, Issue:8

    Topics: Anions; Cell Death; Cell Line, Tumor; Ferric Compounds; Hot Temperature; Humans; Hyperthermia, Induc

2007
A stable propidium iodide staining procedure for flow cytometry.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1982, Volume: 30, Issue:9

    Topics: Animals; DNA; DNA, Neoplasm; Flow Cytometry; Humans; Male; Mice; Neoplasms; Phenanthridines; Propidi

1982
Fluorescent labeling of DNA.
    Methods in molecular biology (Clifton, N.J.), 1994, Volume: 34

    Topics: Animals; Cell Cycle; Cell Separation; DNA; DNA, Neoplasm; Flow Cytometry; Fluorescent Dyes; Histocyt

1994
Deparaffinization and processing of pathologic material.
    Methods in molecular biology (Clifton, N.J.), 1994, Volume: 34

    Topics: Aneuploidy; Cell Nucleus; Cell Separation; DNA; DNA, Neoplasm; Flow Cytometry; Histological Techniqu

1994
One-tube triple staining method for flow cytometric analysis of DNA ploidy and phenotypic heterogeneity of human solid tumors using single laser excitation.
    Cytometry, 1996, Dec-01, Volume: 25, Issue:4

    Topics: Biomarkers; Cell Survival; Coloring Agents; DNA, Neoplasm; Female; Flow Cytometry; Fluorescein-5-iso

1996
Telomere analysis by fluorescence in situ hybridization and flow cytometry.
    Nucleic acids research, 1998, Aug-15, Volume: 26, Issue:16

    Topics: Base Sequence; Blotting, Southern; Bone Marrow Cells; Cell Cycle; Cell Line; DNA; DNA Replication; D

1998
Heat pretreatment increases resolution in DNA flow cytometry of paraffin-embedded tumor tissue.
    Cytometry, 1999, Mar-01, Volume: 35, Issue:3

    Topics: Breast Neoplasms; Cell Separation; Colon; Colorectal Neoplasms; Dose-Response Relationship, Drug; Fl

1999
NASA/American Cancer Society High-Resolution Flow Cytometry Project - II. Effect of pH and DAPI concentration on dual parametric analysis of DNA/DAPI fluorescence and electronic nuclear volume.
    Cytometry, 2001, Jan-01, Volume: 43, Issue:1

    Topics: American Cancer Society; Aneuploidy; Animals; Cell Line; Cell Nucleus; DNA; Erythrocytes; Female; Fl

2001
Melanoma differentiation associated gene-7 (mda-7): a novel anti-tumor gene for cancer gene therapy.
    Molecular medicine (Cambridge, Mass.), 2001, Volume: 7, Issue:4

    Topics: Adenoviridae; Annexin A5; Blotting, Western; Cell Division; Cell Line; Cell Separation; Chromosome M

2001
Flow cytometric analysis of terminal deoxynucleotidyl transferase.
    American journal of clinical pathology, 1991, Volume: 95, Issue:3

    Topics: DNA Nucleotidylexotransferase; Flow Cytometry; Fluorescent Antibody Technique; Hematologic Diseases;

1991
[Estimation of cell viability by FCM using rhodamin 123 and propidum iodide--its application in evaluating the effect of anticancer drugs to tumor cells].
    Gan no rinsho. Japan journal of cancer clinics, 1988, Volume: 34, Issue:1

    Topics: Antineoplastic Agents; Cell Survival; Flow Cytometry; Humans; Neoplasms; Phenanthridines; Propidium;

1988
The PIT method: an automated in vitro technique for drug toxicity testing.
    Investigational new drugs, 1987, Volume: 5, Issue:2

    Topics: Antineoplastic Agents; Cell Line; Cell Survival; Fluorescence; Humans; Neoplasms; Octoxynol; Polyeth

1987
Esterase activity, exclusion of propidium iodide, and proliferation in tumor cells exposed to anticancer agents: phenomena relevant to chemosensitivity determinations.
    Cancer investigation, 1985, Volume: 3, Issue:5

    Topics: Antineoplastic Agents; Cell Division; Cell Line; Cell Survival; Colony-Forming Units Assay; Esterase

1985