propidium has been researched along with Myelodysplastic Syndromes in 3 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Myelodysplastic Syndromes: Clonal hematopoietic stem cell disorders characterized by dysplasia in one or more hematopoietic cell lineages. They predominantly affect patients over 60, are considered preleukemic conditions, and have high probability of transformation into ACUTE MYELOID LEUKEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "By staining human bone marrow cells with a monoclonal antibody reacting with erythroid precursor cells (AS-E1) and propidium iodide, we have evaluated the proliferative capacity of erythropoiesis in patients with myelodysplastic syndromes (MDS) using flow cytometry." | 3.68 | A quantitative evaluation of erythropoiesis in myelodysplastic syndromes using multiparameter flow cytometry. ( Hokland, M; Hokland, P; Jensen, IM, 1993) |
| "Propidium iodide (PI) DNA distribution of bone marrow (BM) cells was studied by flow cytometry (FCM) in 36 patients without hematologic or malignant disease (normal BM) and in 172 patients with anemias (36 pts), myelodysplastic syndromes (MDS) (33 pts) and acute leukemia (AL) at diagnosis (60 pts), remission (24 pts) and relapse (19 pts)." | 3.67 | Flow cytometric evaluation of proliferative activity and ploidy in myelodysplastic syndromes and acute leukemias. ( Danova, M; Giordano, PA; Mazzini, G; Montecucco, CM; Pasquali, F; Riccardi, A; Ucci, G, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jensen, IM | 1 |
| Hokland, M | 1 |
| Hokland, P | 1 |
| Yamamoto, T | 1 |
| Shichishima, T | 1 |
| Shikama, Y | 1 |
| Saitoh, Y | 1 |
| Ogawa, K | 1 |
| Maruyama, Y | 1 |
| Riccardi, A | 1 |
| Montecucco, CM | 1 |
| Danova, M | 1 |
| Ucci, G | 1 |
| Mazzini, G | 1 |
| Giordano, PA | 1 |
| Pasquali, F | 1 |
3 other studies available for propidium and Myelodysplastic Syndromes
| Article | Year |
|---|---|
A quantitative evaluation of erythropoiesis in myelodysplastic syndromes using multiparameter flow cytometry.
Topics: Antibodies, Monoclonal; Bone Marrow; Cell Count; Cell Cycle; Cell Division; Erythroid Precursor Cell | 1993 |
Granulocytes from patients with paroxysmal nocturnal hemoglobinuria and normal individuals have the same sensitivity to spontaneous apoptosis.
Topics: Adult; Aged; Annexin A5; Antibodies, Monoclonal; Apoptosis; Caspase 3; Caspases; CD59 Antigens; Cell | 2002 |
Flow cytometric evaluation of proliferative activity and ploidy in myelodysplastic syndromes and acute leukemias.
Topics: Acute Disease; Cell Division; DNA, Neoplasm; Flow Cytometry; Fluorescent Dyes; Humans; Karyotyping; | 1986 |