propidium has been researched along with Multiple Sclerosis in 2 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitoxantrone is an anti-neoplastic anthracenedione derivative that, based on its immunosuppressive properties, is approved for the treatment of severe forms of relapsing-remitting or secondary progressive multiple sclerosis (MS)." | 7.73 | Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro. ( Archelos, JJ; Hartung, HP; Hemmer, B; Kieseier, BC; Neuhaus, O; Stüve, O; Wiendl, H, 2005) |
| "Mitoxantrone is an anti-neoplastic anthracenedione derivative that, based on its immunosuppressive properties, is approved for the treatment of severe forms of relapsing-remitting or secondary progressive multiple sclerosis (MS)." | 3.73 | Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro. ( Archelos, JJ; Hartung, HP; Hemmer, B; Kieseier, BC; Neuhaus, O; Stüve, O; Wiendl, H, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Neuhaus, O | 1 |
| Wiendl, H | 1 |
| Kieseier, BC | 1 |
| Archelos, JJ | 1 |
| Hemmer, B | 1 |
| Stüve, O | 1 |
| Hartung, HP | 1 |
| Studzinski, DM | 1 |
| Benjamins, JA | 1 |
2 other studies available for propidium and Multiple Sclerosis
| Article | Year |
|---|---|
Multiple sclerosis: Mitoxantrone promotes differential effects on immunocompetent cells in vitro.
Topics: Adult; Annexin A5; Blood Cells; Cell Death; Cell Differentiation; Cells, Cultured; Cytokines; Dendri | 2005 |
Cyclic AMP differentiation of the oligodendroglial cell line N20.1 switches staurosporine-induced cell death from necrosis to apoptosis.
Topics: Animals; Apoptosis; Caspase Inhibitors; Caspases; Cell Differentiation; Cell Line, Transformed; Cell | 2001 |