Page last updated: 2024-11-03

propidium and Melanoma

propidium has been researched along with Melanoma in 12 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"The results provide evidence for the mechanisms of action of jacaranone and emphasize the potential use of this quinone for the treatment of melanoma."7.78Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo. ( Arruda, DC; Farias, CF; Favero, OA; Ferreira, MJ; Figueiredo, CR; Girola, N; Lago, JH; Massaoka, MH; Matsuo, AL; Romoff, P; Scutti, JA; Travassos, LR, 2012)
"This report describes a method by which mitotic cells were isolated from nonsynchronized Cloudman melanoma cells that had been pulse labeled with 5-bromo-2'-deoxyuridine (BrdUrd) and double-stained with a fluoresceinated monoclonal antibody to BrdUrd and with propidium iodide (PI)."7.67Differentiation of mitotic melanoma cells from G2 cells and their isolation by use of 5-bromo-2'-deoxyuridine and propidium iodide. ( Abdel-Malek, ZA; Nordlund, JJ; Swope, VB; Trinkle, LS, 1988)
"Curcumin treatment also altered the expressions of apoptosis associated proteins NF-κB, p38 and p53."5.42Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells. ( Jiang, AJ; Jiang, G; Li, LT; Zheng, JN, 2015)
"LGG-SN alone or in combination with either 5-Fuorouracil and Irinotecan was used to treat human colon and human melanoma cancer cell lines."4.31Lactobacillus rhamnosus GG cell-free supernatant as a novel anti-cancer adjuvant. ( Falzone, L; Gattuso, G; Libra, M; Ricci, D; Salemi, R; Santagati, M; Scillato, M; Vivarelli, S, 2023)
"The results provide evidence for the mechanisms of action of jacaranone and emphasize the potential use of this quinone for the treatment of melanoma."3.78Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo. ( Arruda, DC; Farias, CF; Favero, OA; Ferreira, MJ; Figueiredo, CR; Girola, N; Lago, JH; Massaoka, MH; Matsuo, AL; Romoff, P; Scutti, JA; Travassos, LR, 2012)
"Cisplatin-induced cell death was evaluated in human proximal tubular HK-2, lung carcinoma H460, and melanoma G361 cells using MTT, Hoechst 33342, and propidium iodide assays."3.77Silymarin selectively protects human renal cells from cisplatin-induced cell death. ( Chanvorachote, P; Chaotham, C; Ninsontia, C; Pongjit, K, 2011)
"This report describes a method by which mitotic cells were isolated from nonsynchronized Cloudman melanoma cells that had been pulse labeled with 5-bromo-2'-deoxyuridine (BrdUrd) and double-stained with a fluoresceinated monoclonal antibody to BrdUrd and with propidium iodide (PI)."3.67Differentiation of mitotic melanoma cells from G2 cells and their isolation by use of 5-bromo-2'-deoxyuridine and propidium iodide. ( Abdel-Malek, ZA; Nordlund, JJ; Swope, VB; Trinkle, LS, 1988)
"Curcumin treatment also altered the expressions of apoptosis associated proteins NF-κB, p38 and p53."1.42Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells. ( Jiang, AJ; Jiang, G; Li, LT; Zheng, JN, 2015)
" Also, the dual-luciferase reporter vectors encoding Photinus pyralis firefly or Renilla reniformis luciferase showed a linear increase in dose-response with increasing amounts of transfected DNA, but at higher levels of transfected DNA, a reduction in expressed levels of luciferase activity resulted."1.33Inhibitory effects associated with use of modified Photinus pyralis and Renilla reniformis luciferase vectors in dual reporter assays and implications for analysis of ISGs. ( Cutler, SJ; Ghazawi, I; Low, P; Mellick, AS; Ralph, SJ, 2005)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19902 (16.67)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's3 (25.00)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Salemi, R1
Vivarelli, S1
Ricci, D1
Scillato, M1
Santagati, M1
Gattuso, G1
Falzone, L1
Libra, M1
Jiang, AJ1
Jiang, G1
Li, LT1
Zheng, JN1
Ninsontia, C1
Pongjit, K1
Chaotham, C1
Chanvorachote, P1
Massaoka, MH1
Matsuo, AL1
Figueiredo, CR1
Farias, CF1
Girola, N1
Arruda, DC1
Scutti, JA1
Romoff, P1
Favero, OA1
Ferreira, MJ1
Lago, JH1
Travassos, LR1
Ghosh, R1
Ott, AM1
Seetharam, D1
Slaga, TJ1
Kumar, AP1
Ghazawi, I1
Cutler, SJ1
Low, P1
Mellick, AS1
Ralph, SJ1
Posen, Y1
Kalchenko, V1
Seger, R1
Brandis, A1
Scherz, A1
Salomon, Y1
Zhang, XD1
Wu, JJ1
Gillespie, S1
Borrow, J1
Hersey, P1
Okrój, M1
Stawikowska, D1
Słomińska, EM1
Myśliwski, A1
Bigda, J1
Pullen, GR1
Chalmers, PJ1
Nind, AP1
Nairn, RC1
Benbow, U1
Orndorff, KA1
Brinckerhoff, CE1
Givan, AL1
Trinkle, LS1
Swope, VB1
Abdel-Malek, ZA1
Nordlund, JJ1

Other Studies

12 other studies available for propidium and Melanoma

ArticleYear
Lactobacillus rhamnosus GG cell-free supernatant as a novel anti-cancer adjuvant.
    Journal of translational medicine, 2023, 03-14, Volume: 21, Issue:1

    Topics: Adjuvants, Immunologic; Colon; Humans; Irinotecan; Lacticaseibacillus rhamnosus; Melanoma; Probiotic

2023
Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells.
    Molecular biology reports, 2015, Volume: 42, Issue:1

    Topics: Annexin A5; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; DNA

2015
Silymarin selectively protects human renal cells from cisplatin-induced cell death.
    Pharmaceutical biology, 2011, Volume: 49, Issue:10

    Topics: Acute Kidney Injury; Antineoplastic Agents; Antioxidants; Apoptosis; Benzimidazoles; Cell Death; Cel

2011
Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Acetylcysteine; Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Asteraceae; Benzoquinones; Bl

2012
Cell cycle block and apoptosis induction in a human melanoma cell line following treatment with 2-methoxyoestradiol: therapeutic implications?
    Melanoma research, 2003, Volume: 13, Issue:2

    Topics: 2-Methoxyestradiol; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Cycle; Cell Divis

2003
Inhibitory effects associated with use of modified Photinus pyralis and Renilla reniformis luciferase vectors in dual reporter assays and implications for analysis of ISGs.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2005, Volume: 25, Issue:2

    Topics: Animals; Cell Line, Tumor; Fireflies; Flow Cytometry; Fluorescent Dyes; Fluorometry; Genes, Reporter

2005
Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species.
    Journal of cell science, 2005, May-01, Volume: 118, Issue:Pt 9

    Topics: Animals; Bacteriochlorophylls; Cell Line, Tumor; Cell Survival; Cell-Free System; Cells, Cultured; D

2005
Human melanoma cells selected for resistance to apoptosis by prolonged exposure to tumor necrosis factor-related apoptosis-inducing ligand are more vulnerable to necrotic cell death induced by cisplatin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Feb-15, Volume: 12, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Caspa

2006
The atypical pattern of cell death in B16F10 melanoma cells treated with TNP-470.
    Cellular & molecular biology letters, 2006, Volume: 11, Issue:3

    Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Annexin A5; Antibiotics, Antineopl

2006
Criteria of cell killing in vitro.
    Journal of immunological methods, 1981, Volume: 43, Issue:1

    Topics: Carcinoma; Cell Adhesion; Cell Survival; Cells, Cultured; Colonic Neoplasms; Complement System Prote

1981
Confocal assay for invasion: use of propidium iodide fluorescence and laser reflectance to quantify the rate of migration of cells through a matrix.
    Cytometry, 2000, Aug-01, Volume: 40, Issue:4

    Topics: Breast Neoplasms; Cell Movement; Diagnostic Imaging; DNA, Neoplasm; Female; Fluorescence; Humans; In

2000
Differentiation of mitotic melanoma cells from G2 cells and their isolation by use of 5-bromo-2'-deoxyuridine and propidium iodide.
    Cytometry, 1988, Volume: 9, Issue:5

    Topics: Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Cycle; Cell Line; DNA, Neoplasm; Flow Cytom

1988