propidium has been researched along with Melanoma in 12 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results provide evidence for the mechanisms of action of jacaranone and emphasize the potential use of this quinone for the treatment of melanoma." | 7.78 | Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo. ( Arruda, DC; Farias, CF; Favero, OA; Ferreira, MJ; Figueiredo, CR; Girola, N; Lago, JH; Massaoka, MH; Matsuo, AL; Romoff, P; Scutti, JA; Travassos, LR, 2012) |
| "This report describes a method by which mitotic cells were isolated from nonsynchronized Cloudman melanoma cells that had been pulse labeled with 5-bromo-2'-deoxyuridine (BrdUrd) and double-stained with a fluoresceinated monoclonal antibody to BrdUrd and with propidium iodide (PI)." | 7.67 | Differentiation of mitotic melanoma cells from G2 cells and their isolation by use of 5-bromo-2'-deoxyuridine and propidium iodide. ( Abdel-Malek, ZA; Nordlund, JJ; Swope, VB; Trinkle, LS, 1988) |
| "Curcumin treatment also altered the expressions of apoptosis associated proteins NF-κB, p38 and p53." | 5.42 | Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells. ( Jiang, AJ; Jiang, G; Li, LT; Zheng, JN, 2015) |
| "LGG-SN alone or in combination with either 5-Fuorouracil and Irinotecan was used to treat human colon and human melanoma cancer cell lines." | 4.31 | Lactobacillus rhamnosus GG cell-free supernatant as a novel anti-cancer adjuvant. ( Falzone, L; Gattuso, G; Libra, M; Ricci, D; Salemi, R; Santagati, M; Scillato, M; Vivarelli, S, 2023) |
| "The results provide evidence for the mechanisms of action of jacaranone and emphasize the potential use of this quinone for the treatment of melanoma." | 3.78 | Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo. ( Arruda, DC; Farias, CF; Favero, OA; Ferreira, MJ; Figueiredo, CR; Girola, N; Lago, JH; Massaoka, MH; Matsuo, AL; Romoff, P; Scutti, JA; Travassos, LR, 2012) |
| "Cisplatin-induced cell death was evaluated in human proximal tubular HK-2, lung carcinoma H460, and melanoma G361 cells using MTT, Hoechst 33342, and propidium iodide assays." | 3.77 | Silymarin selectively protects human renal cells from cisplatin-induced cell death. ( Chanvorachote, P; Chaotham, C; Ninsontia, C; Pongjit, K, 2011) |
| "This report describes a method by which mitotic cells were isolated from nonsynchronized Cloudman melanoma cells that had been pulse labeled with 5-bromo-2'-deoxyuridine (BrdUrd) and double-stained with a fluoresceinated monoclonal antibody to BrdUrd and with propidium iodide (PI)." | 3.67 | Differentiation of mitotic melanoma cells from G2 cells and their isolation by use of 5-bromo-2'-deoxyuridine and propidium iodide. ( Abdel-Malek, ZA; Nordlund, JJ; Swope, VB; Trinkle, LS, 1988) |
| "Curcumin treatment also altered the expressions of apoptosis associated proteins NF-κB, p38 and p53." | 1.42 | Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells. ( Jiang, AJ; Jiang, G; Li, LT; Zheng, JN, 2015) |
| " Also, the dual-luciferase reporter vectors encoding Photinus pyralis firefly or Renilla reniformis luciferase showed a linear increase in dose-response with increasing amounts of transfected DNA, but at higher levels of transfected DNA, a reduction in expressed levels of luciferase activity resulted." | 1.33 | Inhibitory effects associated with use of modified Photinus pyralis and Renilla reniformis luciferase vectors in dual reporter assays and implications for analysis of ISGs. ( Cutler, SJ; Ghazawi, I; Low, P; Mellick, AS; Ralph, SJ, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Salemi, R | 1 |
| Vivarelli, S | 1 |
| Ricci, D | 1 |
| Scillato, M | 1 |
| Santagati, M | 1 |
| Gattuso, G | 1 |
| Falzone, L | 1 |
| Libra, M | 1 |
| Jiang, AJ | 1 |
| Jiang, G | 1 |
| Li, LT | 1 |
| Zheng, JN | 1 |
| Ninsontia, C | 1 |
| Pongjit, K | 1 |
| Chaotham, C | 1 |
| Chanvorachote, P | 1 |
| Massaoka, MH | 1 |
| Matsuo, AL | 1 |
| Figueiredo, CR | 1 |
| Farias, CF | 1 |
| Girola, N | 1 |
| Arruda, DC | 1 |
| Scutti, JA | 1 |
| Romoff, P | 1 |
| Favero, OA | 1 |
| Ferreira, MJ | 1 |
| Lago, JH | 1 |
| Travassos, LR | 1 |
| Ghosh, R | 1 |
| Ott, AM | 1 |
| Seetharam, D | 1 |
| Slaga, TJ | 1 |
| Kumar, AP | 1 |
| Ghazawi, I | 1 |
| Cutler, SJ | 1 |
| Low, P | 1 |
| Mellick, AS | 1 |
| Ralph, SJ | 1 |
| Posen, Y | 1 |
| Kalchenko, V | 1 |
| Seger, R | 1 |
| Brandis, A | 1 |
| Scherz, A | 1 |
| Salomon, Y | 1 |
| Zhang, XD | 1 |
| Wu, JJ | 1 |
| Gillespie, S | 1 |
| Borrow, J | 1 |
| Hersey, P | 1 |
| Okrój, M | 1 |
| Stawikowska, D | 1 |
| Słomińska, EM | 1 |
| Myśliwski, A | 1 |
| Bigda, J | 1 |
| Pullen, GR | 1 |
| Chalmers, PJ | 1 |
| Nind, AP | 1 |
| Nairn, RC | 1 |
| Benbow, U | 1 |
| Orndorff, KA | 1 |
| Brinckerhoff, CE | 1 |
| Givan, AL | 1 |
| Trinkle, LS | 1 |
| Swope, VB | 1 |
| Abdel-Malek, ZA | 1 |
| Nordlund, JJ | 1 |
12 other studies available for propidium and Melanoma
| Article | Year |
|---|---|
Lactobacillus rhamnosus GG cell-free supernatant as a novel anti-cancer adjuvant.
Topics: Adjuvants, Immunologic; Colon; Humans; Irinotecan; Lacticaseibacillus rhamnosus; Melanoma; Probiotic | 2023 |
Curcumin induces apoptosis through mitochondrial pathway and caspases activation in human melanoma cells.
Topics: Annexin A5; Apoptosis; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcumin; DNA | 2015 |
Silymarin selectively protects human renal cells from cisplatin-induced cell death.
Topics: Acute Kidney Injury; Antineoplastic Agents; Antioxidants; Apoptosis; Benzimidazoles; Cell Death; Cel | 2011 |
Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.
Topics: Acetylcysteine; Animals; Annexin A5; Antineoplastic Agents; Apoptosis; Asteraceae; Benzoquinones; Bl | 2012 |
Cell cycle block and apoptosis induction in a human melanoma cell line following treatment with 2-methoxyoestradiol: therapeutic implications?
Topics: 2-Methoxyestradiol; Apoptosis; bcl-2-Associated X Protein; Blotting, Western; Cell Cycle; Cell Divis | 2003 |
Inhibitory effects associated with use of modified Photinus pyralis and Renilla reniformis luciferase vectors in dual reporter assays and implications for analysis of ISGs.
Topics: Animals; Cell Line, Tumor; Fireflies; Flow Cytometry; Fluorescent Dyes; Fluorometry; Genes, Reporter | 2005 |
Manipulation of redox signaling in mammalian cells enabled by controlled photogeneration of reactive oxygen species.
Topics: Animals; Bacteriochlorophylls; Cell Line, Tumor; Cell Survival; Cell-Free System; Cells, Cultured; D | 2005 |
Human melanoma cells selected for resistance to apoptosis by prolonged exposure to tumor necrosis factor-related apoptosis-inducing ligand are more vulnerable to necrotic cell death induced by cisplatin.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Caspa | 2006 |
The atypical pattern of cell death in B16F10 melanoma cells treated with TNP-470.
Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Annexin A5; Antibiotics, Antineopl | 2006 |
Criteria of cell killing in vitro.
Topics: Carcinoma; Cell Adhesion; Cell Survival; Cells, Cultured; Colonic Neoplasms; Complement System Prote | 1981 |
Confocal assay for invasion: use of propidium iodide fluorescence and laser reflectance to quantify the rate of migration of cells through a matrix.
Topics: Breast Neoplasms; Cell Movement; Diagnostic Imaging; DNA, Neoplasm; Female; Fluorescence; Humans; In | 2000 |
Differentiation of mitotic melanoma cells from G2 cells and their isolation by use of 5-bromo-2'-deoxyuridine and propidium iodide.
Topics: Animals; Antibodies, Monoclonal; Bromodeoxyuridine; Cell Cycle; Cell Line; DNA, Neoplasm; Flow Cytom | 1988 |