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propidium and Kahler Disease

propidium has been researched along with Kahler Disease in 16 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Research Excerpts

ExcerptRelevanceReference
" Histone deacetylase inhibitors such as valproic acid (VPA) are promising drugs for cancer therapy since they have been reported to have antiproliferative effects and to induce differentiation in carcinoma and leukemic cells."7.74Valproic acid induces non-apoptotic cell death mechanisms in multiple myeloma cell lines. ( Aouali, N; Berchem, G; Bosseler, M; Brons, NH; Leners, B; Palissot, V; Schwartz, C; Wack, S, 2007)
"The aim of this study was a contemporaneous measurement of plasma cells proliferative and apoptotic activity in patients examined at the time of multiple myeloma (MM) diagnosis before initiation of chemotherapy, focussed on the following aspects: determination of prognostic significance of plasma cell propidium iodide (PC-PI) and annexin-V FITC (PC-AI) indices; optimal cut off of PC-PI and PC-AI with regard to overall survival; calculation of summary kinetic index of plasma cells (PC-PI/AI ratio) for evaluation of its prognostic importance; determination of an index (out of PC-PI, PC-AI and PC-PI/AI) showing the closest relation to prognosis of multiple myeloma."7.73Prognostic significance of plasma cell propidium iodide and annexin-V indices and their mutual ratio in multiple myeloma. ( Bacovsky, J; Dusek, L; Minarik, J; Ordeltova, M; Scudla, V; Zemanova, M, 2006)
"In a group of 117 patients with multiple myeloma (MM) examined at the time of diagnosis, i."5.33Evaluation of plasma cell propidium-iodide and annexin-V indices: their relation to prognosis in multiple myeloma. ( Bacovský, J; Minarík, J; Ordeltová, M; Scudla, V; Zemanová, M, 2005)
"Bruceantin treatment (2."5.32Multiple myeloma regression mediated by bruceantin. ( Christov, K; Cuendet, M; Deng, Y; Hedayat, S; Helson, L; Lantvit, DD; McChesney, JD; Pezzuto, JM, 2004)
" The purine analogue 8-aminoadenosine (8-NH(2)-Ado) is known to be a transcription inhibitor that has proved very effective in multiple myeloma cell lines and primary indolent leukemia cells."3.778-Aminoadenosine enhances radiation-induced cell death in human lung carcinoma A549 cells. ( Eitaki, M; Inanami, O; Matsuda, A; Meike, S; Yamamori, T; Yasui, H, 2011)
" Histone deacetylase inhibitors such as valproic acid (VPA) are promising drugs for cancer therapy since they have been reported to have antiproliferative effects and to induce differentiation in carcinoma and leukemic cells."3.74Valproic acid induces non-apoptotic cell death mechanisms in multiple myeloma cell lines. ( Aouali, N; Berchem, G; Bosseler, M; Brons, NH; Leners, B; Palissot, V; Schwartz, C; Wack, S, 2007)
"The aim of this study was a contemporaneous measurement of plasma cells proliferative and apoptotic activity in patients examined at the time of multiple myeloma (MM) diagnosis before initiation of chemotherapy, focussed on the following aspects: determination of prognostic significance of plasma cell propidium iodide (PC-PI) and annexin-V FITC (PC-AI) indices; optimal cut off of PC-PI and PC-AI with regard to overall survival; calculation of summary kinetic index of plasma cells (PC-PI/AI ratio) for evaluation of its prognostic importance; determination of an index (out of PC-PI, PC-AI and PC-PI/AI) showing the closest relation to prognosis of multiple myeloma."3.73Prognostic significance of plasma cell propidium iodide and annexin-V indices and their mutual ratio in multiple myeloma. ( Bacovsky, J; Dusek, L; Minarik, J; Ordeltova, M; Scudla, V; Zemanova, M, 2006)
"Bone marrow cells of 82 patients with multiple myeloma were subjected to flow cytometric analysis of DNA and cytoplasmic immunoglobulin (CIg) content using propidium iodide and direct immunofluorescence assays."3.67Cytoplasmic immunoglobulin content in multiple myeloma. ( Alexanian, R; Barlogie, B; Pershouse, M; Smallwood, L; Smith, L, 1985)
"In a group of 117 patients with multiple myeloma (MM) examined at the time of diagnosis, i."1.33Evaluation of plasma cell propidium-iodide and annexin-V indices: their relation to prognosis in multiple myeloma. ( Bacovský, J; Minarík, J; Ordeltová, M; Scudla, V; Zemanová, M, 2005)
"Bruceantin treatment (2."1.32Multiple myeloma regression mediated by bruceantin. ( Christov, K; Cuendet, M; Deng, Y; Hedayat, S; Helson, L; Lantvit, DD; McChesney, JD; Pezzuto, JM, 2004)
"Previous studies have suggested that multiple myeloma (MM) cells express estrogen receptors (ER)."1.30Anti-estrogens induce apoptosis of multiple myeloma cells. ( Anderson, KC; Chauhan, D; Ogata, A; Teoh, G; Treon, SP; Urashima, M; Webb, IJ, 1998)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19902 (12.50)18.7374
1990's4 (25.00)18.2507
2000's8 (50.00)29.6817
2010's2 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schmeel, FC1
Schmeel, LC1
Kim, Y1
Schmidt-Wolf, IG1
Meike, S1
Yamamori, T1
Yasui, H1
Eitaki, M1
Matsuda, A1
Inanami, O1
Scudla, V3
Ordeltova, M3
Bacovsky, J3
Vytrasova, M1
Sumna, E1
Martinek, A1
Horak, P1
Cuendet, M1
Christov, K1
Lantvit, DD1
Deng, Y1
Hedayat, S1
Helson, L1
McChesney, JD1
Pezzuto, JM1
Fandy, TE1
Shankar, S1
Ross, DD1
Sausville, E1
Srivastava, RK1
Minarík, J2
Zemanová, M2
Dusek, L1
Schwartz, C1
Palissot, V1
Aouali, N1
Wack, S1
Brons, NH1
Leners, B1
Bosseler, M1
Berchem, G1
Baumal, R1
Musclow, E1
Farkas-Himsley, H1
Marks, A1
Orfäo, A1
García-Sanz, R1
López-Berges, MC1
Belén Vidriales, M1
González, M1
Caballero, MD1
San Miguel, JF1
Djuzenova, CS1
Zimmermann, U2
Frank, H1
Sukhorukov, VL2
Richter, E1
Fuhr, G1
Treon, SP1
Teoh, G1
Urashima, M1
Ogata, A1
Chauhan, D1
Webb, IJ1
Anderson, KC1
Fosså, A1
Brandhorst, D1
Myklebust, JH1
Seeber, S1
Nowrousian, MR1
Müller, KJ1
Hradcová, M1
Marinov, I1
Novák, JT1
Nemcová, J1
Stöckbauer, P1
Barlogie, B1
Alexanian, R1
Pershouse, M1
Smallwood, L1
Smith, L1

Other Studies

16 other studies available for propidium and Kahler Disease

ArticleYear
Piceatannol exhibits selective toxicity to multiple myeloma cells and influences the Wnt/ beta-catenin pathway.
    Hematological oncology, 2014, Volume: 32, Issue:4

    Topics: Animals; Apoptosis; beta Catenin; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Fi

2014
8-Aminoadenosine enhances radiation-induced cell death in human lung carcinoma A549 cells.
    Journal of radiation research, 2011, Volume: 52, Issue:4

    Topics: Adenocarcinoma; Adenosine; Adenosine Triphosphate; Apoptosis; Caspase Inhibitors; Cell Death; Cell L

2011
A contribution to examination of propidium iodide and annexin V plasma cells indices in multiple myeloma.
    Neoplasma, 2003, Volume: 50, Issue:5

    Topics: Annexin A5; Apoptosis; Cell Division; Coloring Agents; Humans; Monoclonal Gammopathy of Undetermined

2003
Multiple myeloma regression mediated by bruceantin.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Feb-01, Volume: 10, Issue:3

    Topics: Animals; Apoptosis; BH3 Interacting Domain Death Agonist Protein; Carbocyanines; Carrier Proteins; C

2004
Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:7

    Topics: Amino Acid Chloromethyl Ketones; Annexin A5; Apoptosis; Apoptosis Regulatory Proteins; Calpain; Casp

2005
Evaluation of plasma cell propidium-iodide and annexin-V indices: their relation to prognosis in multiple myeloma.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2005, Volume: 149, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Annexin A5; Apoptosis; Cell Proliferation; Female; Humans; Male; Mid

2005
Prognostic significance of plasma cell propidium iodide and annexin-V indices and their mutual ratio in multiple myeloma.
    Neoplasma, 2006, Volume: 53, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Annexin A5; Apoptosis; Cell Proliferation; Female; Humans; Male; Mid

2006
Valproic acid induces non-apoptotic cell death mechanisms in multiple myeloma cell lines.
    International journal of oncology, 2007, Volume: 30, Issue:3

    Topics: Apoptosis; Cadaverine; Carcinoma; Caspases; Cell Cycle; Cell Death; Cell Line, Tumor; Cell Survival;

2007
Variants of an interspecies hybridoma with altered tumorigenicity and protective ability against mouse myeloma tumors.
    Cancer research, 1982, Volume: 42, Issue:5

    Topics: Animals; Bacteriocins; Cell Line; Cell Membrane; Flow Cytometry; Hybridomas; Mice; Mice, Inbred BALB

1982
A new method for the analysis of plasma cell DNA content in multiple myeloma samples using a CD38/propidium iodide double staining technique.
    Cytometry, 1994, Dec-01, Volume: 17, Issue:4

    Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Biomarkers, Tumor; Bone Marrow; Cell Cycle; DNA, Ne

1994
Effect of medium conductivity and composition on the uptake of propidium iodide into electropermeabilized myeloma cells.
    Biochimica et biophysica acta, 1996, Oct-23, Volume: 1284, Issue:2

    Topics: Animals; Cell Line; Cell Membrane; Culture Media; Electric Conductivity; Electroporation; Kinetics;

1996
Anti-estrogens induce apoptosis of multiple myeloma cells.
    Blood, 1998, Sep-01, Volume: 92, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cell Division; Cell Survival; Coloring Agents; Estradiol; Estrogen Anta

1998
Relation between S-phase fraction of myeloma cells and anemia in patients with multiple myeloma.
    Experimental hematology, 1999, Volume: 27, Issue:11

    Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Anemia; Antigens, CD; Antigens, Differentiation; Cell Cy

1999
Reversible electropermeabilization of mammalian cells by high-intensity, ultra-short pulses of submicrosecond duration.
    The Journal of membrane biology, 2001, Nov-15, Volume: 184, Issue:2

    Topics: Animals; Cell Membrane Permeability; Electric Conductivity; Electric Stimulation; Electroporation; F

2001
Monoclonal antibody to human chronic myeloid leukemia cell line MOLM-7 specifically reacts with an antigen of apoptotic cells.
    Leukemia research, 2002, Volume: 26, Issue:1

    Topics: Animals; Antibodies, Monoclonal; Antigens, Neoplasm; Antineoplastic Agents, Phytogenic; Apoptosis; C

2002
Cytoplasmic immunoglobulin content in multiple myeloma.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:2

    Topics: Bone Marrow Cells; Cytoplasm; DNA; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoele

1985