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propidium and Idiopathic Parkinson Disease

propidium has been researched along with Idiopathic Parkinson Disease in 3 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Research Excerpts

ExcerptRelevanceReference
" A combination of Annexin V binding and propidium iodide (PI) exclusion was used to distinguish apoptosis from necrosis in flow cytometry experiments and FACS profiles of permeabilised PI-labelled cells were employed for the assessment of cell cycle distribution."7.73Isatin, an endogenous monoamine oxidase inhibitor, triggers a dose- and time-dependent switch from apoptosis to necrosis in human neuroblastoma cells. ( Glover, V; Igosheva, N; Lorz, C; Mehmet, H; O'Conner, E, 2005)
" A combination of Annexin V binding and propidium iodide (PI) exclusion was used to distinguish apoptosis from necrosis in flow cytometry experiments and FACS profiles of permeabilised PI-labelled cells were employed for the assessment of cell cycle distribution."3.73Isatin, an endogenous monoamine oxidase inhibitor, triggers a dose- and time-dependent switch from apoptosis to necrosis in human neuroblastoma cells. ( Glover, V; Igosheva, N; Lorz, C; Mehmet, H; O'Conner, E, 2005)
"The cause of dopaminergic cell death in Parkinson's disease (PD) remains unknown, but may involve oxidative stress and mitochondrial complex I deficiency."1.30Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins. ( Cooper, JM; Schapira, AH; Seaton, TA, 1998)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moldzio, R1
Piskernik, C1
Radad, K1
Rausch, WD1
Igosheva, N1
Lorz, C1
O'Conner, E1
Glover, V1
Mehmet, H1
Seaton, TA1
Cooper, JM1
Schapira, AH1

Other Studies

3 other studies available for propidium and Idiopathic Parkinson Disease

ArticleYear
Rotenone damages striatal organotypic slice culture.
    Annals of the New York Academy of Sciences, 2008, Volume: 1148

    Topics: Animals; Corpus Striatum; Indicators and Reagents; Insecticides; L-Lactate Dehydrogenase; Mice; Mice

2008
Isatin, an endogenous monoamine oxidase inhibitor, triggers a dose- and time-dependent switch from apoptosis to necrosis in human neuroblastoma cells.
    Neurochemistry international, 2005, Volume: 47, Issue:3

    Topics: Annexin A5; Antiparkinson Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Membrane Permeabilit

2005
Cyclosporin inhibition of apoptosis induced by mitochondrial complex I toxins.
    Brain research, 1998, Oct-26, Volume: 809, Issue:1

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Coloring Agents; Cyclosporine; Dopamine Agents; Enz

1998