propidium has been researched along with Hepatolenticular Degeneration in 1 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Hepatolenticular Degeneration: A rare autosomal recessive disease characterized by the deposition of copper in the BRAIN; LIVER; CORNEA; and other organs. It is caused by defects in the ATP7B gene encoding copper-transporting ATPase 2 (EC 3.6.3.4), also known as the Wilson disease protein. The overload of copper inevitably leads to progressive liver and neurological dysfunction such as LIVER CIRRHOSIS; TREMOR; ATAXIA and intellectual deterioration. Hepatic dysfunction may precede neurologic dysfunction by several years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Wilson's disease is a genetic disorder characterized by the accumulation of copper in the body due to a defect of biliary copper excretion." | 1.31 | Copper does not alter the intracellular distribution of ATP7B, a copper-transporting ATPase. ( Baba, S; Furuta, K; Hanada, S; Harada, M; Kawaguchi, T; Kimura, R; Koga, H; Kumashiro, R; Sakisaka, S; Sata, M; Sugiyama, T; Taniguchi, E, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harada, M | 1 |
| Sakisaka, S | 1 |
| Kawaguchi, T | 1 |
| Kimura, R | 1 |
| Taniguchi, E | 1 |
| Koga, H | 1 |
| Hanada, S | 1 |
| Baba, S | 1 |
| Furuta, K | 1 |
| Kumashiro, R | 1 |
| Sugiyama, T | 1 |
| Sata, M | 1 |
1 other study available for propidium and Hepatolenticular Degeneration
| Article | Year |
|---|---|
Copper does not alter the intracellular distribution of ATP7B, a copper-transporting ATPase.
Topics: Adenosine Triphosphatases; Antigens, CD; Biological Transport; Biomarkers; Carcinoma, Hepatocellular | 2000 |