Page last updated: 2024-11-03

propidium and Glioma

propidium has been researched along with Glioma in 13 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Gliomas are the most common and devastating tumors of the central nervous system."5.35Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study. ( Battastini, AM; Bavaresco, L; Bernardi, A; Figueiró, F; Frozza, RL; Guterres, SS; Jäger, E; Pohlmann, AR; Salbego, C, 2008)
" The aim of this study was to evaluate the effect of methylglyoxal exposure, over short (1 and 3 h) and long term (24 h) periods, on glucose, glycine and lactate metabolism in C6 glioma cells, as well as investigate the glyoxalase system and AGEs formation."3.78Methylglyoxal alters glucose metabolism and increases AGEs content in C6 glioma cells. ( Bobermin, LD; de Souza, DF; Fontoura, JB; Gonçalves, CA; Hansen, F; Hoefel, AL; Leite, MC; Perry, ML; Silveira, Sda L; Tramontina, AC, 2012)
" Results demonstrate that smaller size of MWCNT seems to be more toxic than that of larger one."1.38In vitro toxicity of multi-walled carbon nanotubes in C6 rat glioma cells. ( Han, YG; Li, ZG; Ren, GG; Xu, J; Yang, Z, 2012)
"Gliomas are the most common and devastating tumors of the central nervous system."1.35Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study. ( Battastini, AM; Bavaresco, L; Bernardi, A; Figueiró, F; Frozza, RL; Guterres, SS; Jäger, E; Pohlmann, AR; Salbego, C, 2008)
"Propidium iodide was employed for nuclear DNA staining."1.27Ploidy and proliferative activity of human brain tumors. A flow cytofluorometric study. ( Ascari, E; Butti, G; Danova, M; Gaetani, P; Knerich, R; Mazzini, G; Riccardi, A; Silvani, V; Ucci, G, 1987)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's2 (15.38)18.2507
2000's5 (38.46)29.6817
2010's5 (38.46)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gu, XQ1
Pamenter, ME1
Siemen, D1
Sun, X1
Haddad, GG1
Quincozes-Santos, A2
Nardin, P2
de Souza, DF2
Gelain, DP1
Moreira, JC1
Latini, A1
Gonçalves, CA3
Gottfried, C2
Marzocco, S1
Popolo, A1
Bianco, G1
Pinto, A1
Autore, G1
Mirbahai, L1
Wilson, M1
Shaw, CS1
McConville, C1
Malcomson, RD1
Kauppinen, RA1
Peet, AC1
Han, YG1
Xu, J1
Li, ZG1
Ren, GG1
Yang, Z1
Hansen, F1
Silveira, Sda L1
Hoefel, AL1
Fontoura, JB1
Tramontina, AC1
Bobermin, LD1
Leite, MC1
Perry, ML1
Trentin, GA1
He, Y1
Wu, DC1
Tang, D1
Rozakis-Adcock, M1
Krajcí, D1
Mares, V1
Lisá, V1
Bottone, MG2
Pellicciari, C2
Andreazza, AC1
Funchal, C1
Bernardi, A1
Frozza, RL1
Jäger, E1
Figueiró, F1
Bavaresco, L1
Salbego, C1
Pohlmann, AR1
Guterres, SS1
Battastini, AM1
Mangiarotti, R1
Danova, M2
Wang, E1
Adler, M1
Shafer, H1
Hamilton, T1
Petrali, JP1
Riccardi, A1
Mazzini, G1
Ucci, G1
Gaetani, P1
Silvani, V1
Knerich, R1
Butti, G1
Ascari, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of Topical Application of 5% Imiquimod, 0.05% Imiquimod and 0.05% Nanoencapsulated Imiquimod Gel in the Treatment of Actinic Cheilitis: a Randomized Controlled Trial[NCT04219358]Phase 149 participants (Actual)Interventional2019-03-23Terminated (stopped due to Study terminated because of COVID19 pandemics.)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

13 other studies available for propidium and Glioma

ArticleYear
Mitochondrial but not plasmalemmal BK channels are hypoxia-sensitive in human glioma.
    Glia, 2014, Volume: 62, Issue:4

    Topics: Adenosine Triphosphate; Calcium; Cell Line, Tumor; Cell Membrane; Charybdotoxin; Glioma; Humans; Hyp

2014
The janus face of resveratrol in astroglial cells.
    Neurotoxicity research, 2009, Volume: 16, Issue:1

    Topics: Actins; Analysis of Variance; Animals; Antioxidants; Astrocytes; Dose-Response Relationship, Drug; D

2009
Pro-apoptotic effect of methylguanidine on hydrogen peroxide-treated rat glioma cell line.
    Neurochemistry international, 2010, Volume: 57, Issue:5

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Blotting, Western; Br

2010
Lipid biomarkers of glioma cell growth arrest and cell death detected by 1 H magic angle spinning MRS.
    NMR in biomedicine, 2012, Volume: 25, Issue:11

    Topics: Animals; Annexin A5; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; C

2012
In vitro toxicity of multi-walled carbon nanotubes in C6 rat glioma cells.
    Neurotoxicology, 2012, Volume: 33, Issue:5

    Topics: Analysis of Variance; Animals; Annexin A5; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; D

2012
Methylglyoxal alters glucose metabolism and increases AGEs content in C6 glioma cells.
    Metabolic brain disease, 2012, Volume: 27, Issue:4

    Topics: Cell Line, Tumor; Coloring Agents; Energy Metabolism; Glioma; Glucose; Glycation End Products, Advan

2012
Identification of a hTid-1 mutation which sensitizes gliomas to apoptosis.
    FEBS letters, 2004, Dec-17, Volume: 578, Issue:3

    Topics: Adenoviridae; Animals; Apoptosis; bcl-X Protein; Blotting, Western; Caspases; Cell Line, Tumor; Chlo

2004
Intranuclear microtubules are hallmarks of an unusual form of cell death in cisplatin-treated C6 glioma cells.
    Histochemistry and cell biology, 2006, Volume: 125, Issue:1-2

    Topics: Actin Cytoskeleton; Annexin A5; Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cell Death; Cell

2006
Resveratrol attenuates oxidative-induced DNA damage in C6 Glioma cells.
    Neurotoxicology, 2007, Volume: 28, Issue:4

    Topics: Analysis of Variance; Animals; Antioxidants; Cell Line, Tumor; Comet Assay; DNA Damage; Dose-Respons

2007
Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study.
    European journal of pharmacology, 2008, May-31, Volume: 586, Issue:1-3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Brain Neoplasms; Cell Count

2008
Identification of resting cells by dual-parameter flow cytometry of statin expression and DNA content.
    Cytometry, 1995, Dec-01, Volume: 21, Issue:4

    Topics: 3T3 Cells; Animals; Antigens, Neoplasm; Apoptosis; Biomarkers; Breast Neoplasms; Bromodeoxyuridine;

1995
Cytotoxic actions of the heavy metal chelator TPEN on NG108-15 neuroblastoma-glioma cells.
    Neurotoxicology, 1999, Volume: 20, Issue:4

    Topics: Animals; Apoptosis; Biomarkers; Cell Aggregation; Cell Nucleus; Cell Survival; Chelating Agents; Chr

1999
Ploidy and proliferative activity of human brain tumors. A flow cytofluorometric study.
    Oncology, 1987, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Aged; Aneuploidy; Brain Neoplasms; DNA, Neoplasm; Evaluation Studies as Topic; Fe

1987