propidium and Glioma
propidium has been researched along with Glioma in 13 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gliomas are the most common and devastating tumors of the central nervous system." | 5.35 | Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study. ( Battastini, AM; Bavaresco, L; Bernardi, A; Figueiró, F; Frozza, RL; Guterres, SS; Jäger, E; Pohlmann, AR; Salbego, C, 2008) |
| " The aim of this study was to evaluate the effect of methylglyoxal exposure, over short (1 and 3 h) and long term (24 h) periods, on glucose, glycine and lactate metabolism in C6 glioma cells, as well as investigate the glyoxalase system and AGEs formation." | 3.78 | Methylglyoxal alters glucose metabolism and increases AGEs content in C6 glioma cells. ( Bobermin, LD; de Souza, DF; Fontoura, JB; Gonçalves, CA; Hansen, F; Hoefel, AL; Leite, MC; Perry, ML; Silveira, Sda L; Tramontina, AC, 2012) |
| " Results demonstrate that smaller size of MWCNT seems to be more toxic than that of larger one." | 1.38 | In vitro toxicity of multi-walled carbon nanotubes in C6 rat glioma cells. ( Han, YG; Li, ZG; Ren, GG; Xu, J; Yang, Z, 2012) |
| "Gliomas are the most common and devastating tumors of the central nervous system." | 1.35 | Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study. ( Battastini, AM; Bavaresco, L; Bernardi, A; Figueiró, F; Frozza, RL; Guterres, SS; Jäger, E; Pohlmann, AR; Salbego, C, 2008) |
| "Propidium iodide was employed for nuclear DNA staining." | 1.27 | Ploidy and proliferative activity of human brain tumors. A flow cytofluorometric study. ( Ascari, E; Butti, G; Danova, M; Gaetani, P; Knerich, R; Mazzini, G; Riccardi, A; Silvani, V; Ucci, G, 1987) |
Research
Studies (13)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 5 (38.46) | 29.6817 |
| 2010's | 5 (38.46) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Gu, XQ | 1 |
| Pamenter, ME | 1 |
| Siemen, D | 1 |
| Sun, X | 1 |
| Haddad, GG | 1 |
| Quincozes-Santos, A | 2 |
| Nardin, P | 2 |
| de Souza, DF | 2 |
| Gelain, DP | 1 |
| Moreira, JC | 1 |
| Latini, A | 1 |
| Gonçalves, CA | 3 |
| Gottfried, C | 2 |
| Marzocco, S | 1 |
| Popolo, A | 1 |
| Bianco, G | 1 |
| Pinto, A | 1 |
| Autore, G | 1 |
| Mirbahai, L | 1 |
| Wilson, M | 1 |
| Shaw, CS | 1 |
| McConville, C | 1 |
| Malcomson, RD | 1 |
| Kauppinen, RA | 1 |
| Peet, AC | 1 |
| Han, YG | 1 |
| Xu, J | 1 |
| Li, ZG | 1 |
| Ren, GG | 1 |
| Yang, Z | 1 |
| Hansen, F | 1 |
| Silveira, Sda L | 1 |
| Hoefel, AL | 1 |
| Fontoura, JB | 1 |
| Tramontina, AC | 1 |
| Bobermin, LD | 1 |
| Leite, MC | 1 |
| Perry, ML | 1 |
| Trentin, GA | 1 |
| He, Y | 1 |
| Wu, DC | 1 |
| Tang, D | 1 |
| Rozakis-Adcock, M | 1 |
| Krajcí, D | 1 |
| Mares, V | 1 |
| Lisá, V | 1 |
| Bottone, MG | 2 |
| Pellicciari, C | 2 |
| Andreazza, AC | 1 |
| Funchal, C | 1 |
| Bernardi, A | 1 |
| Frozza, RL | 1 |
| Jäger, E | 1 |
| Figueiró, F | 1 |
| Bavaresco, L | 1 |
| Salbego, C | 1 |
| Pohlmann, AR | 1 |
| Guterres, SS | 1 |
| Battastini, AM | 1 |
| Mangiarotti, R | 1 |
| Danova, M | 2 |
| Wang, E | 1 |
| Adler, M | 1 |
| Shafer, H | 1 |
| Hamilton, T | 1 |
| Petrali, JP | 1 |
| Riccardi, A | 1 |
| Mazzini, G | 1 |
| Ucci, G | 1 |
| Gaetani, P | 1 |
| Silvani, V | 1 |
| Knerich, R | 1 |
| Butti, G | 1 |
| Ascari, E | 1 |
Clinical Trials (1)
Trial Overview
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Topical Application of 5% Imiquimod, 0.05% Imiquimod and 0.05% Nanoencapsulated Imiquimod Gel in the Treatment of Actinic Cheilitis: a Randomized Controlled Trial[NCT04219358] | Phase 1 | 49 participants (Actual) | Interventional | 2019-03-23 | Terminated (stopped due to Study terminated because of COVID19 pandemics.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Other Studies
13 other studies available for propidium and Glioma
| Article | Year |
|---|---|
Mitochondrial but not plasmalemmal BK channels are hypoxia-sensitive in human glioma.
Topics: Adenosine Triphosphate; Calcium; Cell Line, Tumor; Cell Membrane; Charybdotoxin; Glioma; Humans; Hyp | 2014 |
The janus face of resveratrol in astroglial cells.
Topics: Actins; Analysis of Variance; Animals; Antioxidants; Astrocytes; Dose-Response Relationship, Drug; D | 2009 |
Pro-apoptotic effect of methylguanidine on hydrogen peroxide-treated rat glioma cell line.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Blotting, Western; Br | 2010 |
Lipid biomarkers of glioma cell growth arrest and cell death detected by 1 H magic angle spinning MRS.
Topics: Animals; Annexin A5; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; C | 2012 |
In vitro toxicity of multi-walled carbon nanotubes in C6 rat glioma cells.
Topics: Analysis of Variance; Animals; Annexin A5; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Survival; D | 2012 |
Methylglyoxal alters glucose metabolism and increases AGEs content in C6 glioma cells.
Topics: Cell Line, Tumor; Coloring Agents; Energy Metabolism; Glioma; Glucose; Glycation End Products, Advan | 2012 |
Identification of a hTid-1 mutation which sensitizes gliomas to apoptosis.
Topics: Adenoviridae; Animals; Apoptosis; bcl-X Protein; Blotting, Western; Caspases; Cell Line, Tumor; Chlo | 2004 |
Intranuclear microtubules are hallmarks of an unusual form of cell death in cisplatin-treated C6 glioma cells.
Topics: Actin Cytoskeleton; Annexin A5; Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cell Death; Cell | 2006 |
Resveratrol attenuates oxidative-induced DNA damage in C6 Glioma cells.
Topics: Analysis of Variance; Animals; Antioxidants; Cell Line, Tumor; Comet Assay; DNA Damage; Dose-Respons | 2007 |
Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Brain Neoplasms; Cell Count | 2008 |
Identification of resting cells by dual-parameter flow cytometry of statin expression and DNA content.
Topics: 3T3 Cells; Animals; Antigens, Neoplasm; Apoptosis; Biomarkers; Breast Neoplasms; Bromodeoxyuridine; | 1995 |
Cytotoxic actions of the heavy metal chelator TPEN on NG108-15 neuroblastoma-glioma cells.
Topics: Animals; Apoptosis; Biomarkers; Cell Aggregation; Cell Nucleus; Cell Survival; Chelating Agents; Chr | 1999 |
Ploidy and proliferative activity of human brain tumors. A flow cytofluorometric study.
Topics: Adolescent; Adult; Aged; Aneuploidy; Brain Neoplasms; DNA, Neoplasm; Evaluation Studies as Topic; Fe | 1987 |