Page last updated: 2024-11-03

propidium and Down Syndrome

propidium has been researched along with Down Syndrome in 3 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dogliotti, G1
Galliera, E1
Dozio, E1
Vianello, E1
Villa, RE1
Licastro, F2
Barajon, I1
Corsi, MM2
Gemen, EF1
Verstegen, RH1
Leuvenink, J1
de Vries, E1
Ponti, W1
Venditti, A1
Ferrara, F1
Baldo, C1
Chiappelli, M1

Other Studies

3 other studies available for propidium and Down Syndrome

ArticleYear
Okadaic acid induces apoptosis in Down syndrome fibroblasts.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:3

    Topics: Annexin A5; Apoptosis; Cell Line; Cell Membrane; Coloring Agents; Down Syndrome; Fibroblasts; Flow C

2010
Increased circulating apoptotic lymphocytes in children with Down syndrome.
    Pediatric blood & cancer, 2012, Dec-15, Volume: 59, Issue:7

    Topics: Annexin A5; Apoptosis; Child; Coloring Agents; Down Syndrome; Flow Cytometry; Fluorescein-5-isothioc

2012
Proapoptotic activated T-cells in the blood of children with Down's syndrome: relationship with dietary antigens and intestinal alterations.
    International journal of tissue reactions, 2003, Volume: 25, Issue:3

    Topics: Adolescent; Annexin A5; Antigens; Apoptosis; CD3 Complex; CD4 Antigens; Celiac Disease; Cells, Cultu

2003