propidium has been researched along with Down Syndrome in 3 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Down Syndrome: A chromosome disorder associated either with an extra chromosome 21 or an effective trisomy for chromosome 21. Clinical manifestations include hypotonia, short stature, brachycephaly, upslanting palpebral fissures, epicanthus, Brushfield spots on the iris, protruding tongue, small ears, short, broad hands, fifth finger clinodactyly, Simian crease, and moderate to severe INTELLECTUAL DISABILITY. Cardiac and gastrointestinal malformations, a marked increase in the incidence of LEUKEMIA, and the early onset of ALZHEIMER DISEASE are also associated with this condition. Pathologic features include the development of NEUROFIBRILLARY TANGLES in neurons and the deposition of AMYLOID BETA-PROTEIN, similar to the pathology of ALZHEIMER DISEASE. (Menkes, Textbook of Child Neurology, 5th ed, p213)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Dogliotti, G | 1 |
Galliera, E | 1 |
Dozio, E | 1 |
Vianello, E | 1 |
Villa, RE | 1 |
Licastro, F | 2 |
Barajon, I | 1 |
Corsi, MM | 2 |
Gemen, EF | 1 |
Verstegen, RH | 1 |
Leuvenink, J | 1 |
de Vries, E | 1 |
Ponti, W | 1 |
Venditti, A | 1 |
Ferrara, F | 1 |
Baldo, C | 1 |
Chiappelli, M | 1 |
3 other studies available for propidium and Down Syndrome
Article | Year |
---|---|
Okadaic acid induces apoptosis in Down syndrome fibroblasts.
Topics: Annexin A5; Apoptosis; Cell Line; Cell Membrane; Coloring Agents; Down Syndrome; Fibroblasts; Flow C | 2010 |
Increased circulating apoptotic lymphocytes in children with Down syndrome.
Topics: Annexin A5; Apoptosis; Child; Coloring Agents; Down Syndrome; Flow Cytometry; Fluorescein-5-isothioc | 2012 |
Proapoptotic activated T-cells in the blood of children with Down's syndrome: relationship with dietary antigens and intestinal alterations.
Topics: Adolescent; Annexin A5; Antigens; Apoptosis; CD3 Complex; CD4 Antigens; Celiac Disease; Cells, Cultu | 2003 |