propidium has been researched along with Brain Neoplasms in 12 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gliomas are the most common and devastating tumors of the central nervous system." | 5.35 | Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study. ( Battastini, AM; Bavaresco, L; Bernardi, A; Figueiró, F; Frozza, RL; Guterres, SS; Jäger, E; Pohlmann, AR; Salbego, C, 2008) |
| " Previous results with the preclinical GL261 glioblastoma (GB) showed that combination treatment of temozolomide (TMZ) + CX-4945 (protein kinase CK2 inhibitor) outperformed single treatments, provided an immune-friendly schedule was followed." | 4.02 | Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells. ( Arús, C; Candiota, AP; Martínez-Escardó, L; Villamañan, L; Yuste, VJ, 2021) |
| "Gliomas are the most common and devastating tumors of the central nervous system." | 1.35 | Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study. ( Battastini, AM; Bavaresco, L; Bernardi, A; Figueiró, F; Frozza, RL; Guterres, SS; Jäger, E; Pohlmann, AR; Salbego, C, 2008) |
| "Growth retardation of inoculated brain tumors and prolonged survival of inoculated rats were observed with treatment with the anticancer agents, except cisplatin." | 1.30 | Prediction of drug cytotoxicity in 9L rat brain tumor by using flow cytometry with a deoxyribonucleic acid-binding dye. ( Fujimoto, S; Iwadate, Y; Namba, H; Sueyoshi, K; Tagawa, M; Yamaura, A, 1997) |
| "Propidium iodide was employed for nuclear DNA staining." | 1.27 | Ploidy and proliferative activity of human brain tumors. A flow cytofluorometric study. ( Ascari, E; Butti, G; Danova, M; Gaetani, P; Knerich, R; Mazzini, G; Riccardi, A; Silvani, V; Ucci, G, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 2 (16.67) | 18.2507 |
| 2000's | 3 (25.00) | 29.6817 |
| 2010's | 4 (33.33) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Kadhim, ZA | 1 |
| Sulaiman, GM | 1 |
| Al-Shammari, AM | 1 |
| Khan, RA | 1 |
| Al Rugaie, O | 1 |
| Mohammed, HA | 1 |
| Villamañan, L | 1 |
| Martínez-Escardó, L | 1 |
| Arús, C | 1 |
| Yuste, VJ | 1 |
| Candiota, AP | 1 |
| Dilnawaz, F | 1 |
| Sahoo, SK | 1 |
| Vartholomatos, G | 1 |
| Alexiou, GA | 1 |
| Stefanaki, K | 1 |
| Lykoudis, EG | 1 |
| Tseka, G | 1 |
| Tzoufi, M | 1 |
| Sfakianos, G | 1 |
| Prodromou, N | 1 |
| Marzocco, S | 1 |
| Popolo, A | 1 |
| Bianco, G | 1 |
| Pinto, A | 1 |
| Autore, G | 1 |
| Mirbahai, L | 1 |
| Wilson, M | 1 |
| Shaw, CS | 1 |
| McConville, C | 1 |
| Malcomson, RD | 1 |
| Kauppinen, RA | 1 |
| Peet, AC | 1 |
| Chen, GG | 1 |
| Sin, FL | 1 |
| Leung, BC | 1 |
| Ng, HK | 1 |
| Poon, WS | 1 |
| Krajcí, D | 1 |
| Mares, V | 1 |
| Lisá, V | 1 |
| Bottone, MG | 1 |
| Pellicciari, C | 1 |
| Bernardi, A | 1 |
| Frozza, RL | 1 |
| Jäger, E | 1 |
| Figueiró, F | 1 |
| Bavaresco, L | 1 |
| Salbego, C | 1 |
| Pohlmann, AR | 1 |
| Guterres, SS | 1 |
| Battastini, AM | 1 |
| Wang, J | 1 |
| Basu, HS | 1 |
| Hu, L | 1 |
| Feuerstein, BG | 1 |
| Nederlof, PM | 1 |
| Deen, DF | 1 |
| Iwadate, Y | 1 |
| Fujimoto, S | 1 |
| Sueyoshi, K | 1 |
| Namba, H | 1 |
| Tagawa, M | 1 |
| Yamaura, A | 1 |
| Danova, M | 1 |
| Riccardi, A | 1 |
| Mazzini, G | 1 |
| Ucci, G | 1 |
| Gaetani, P | 1 |
| Silvani, V | 1 |
| Knerich, R | 1 |
| Butti, G | 1 |
| Ascari, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of Topical Application of 5% Imiquimod, 0.05% Imiquimod and 0.05% Nanoencapsulated Imiquimod Gel in the Treatment of Actinic Cheilitis: a Randomized Controlled Trial[NCT04219358] | Phase 1 | 49 participants (Actual) | Interventional | 2019-03-23 | Terminated (stopped due to Study terminated because of COVID19 pandemics.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 other studies available for propidium and Brain Neoplasms
| Article | Year |
|---|---|
Oncolytic Newcastle Disease Virus Co-Delivered with Modified PLGA Nanoparticles Encapsulating Temozolomide against Glioblastoma Cells: Developing an Effective Treatment Strategy.
Topics: Acridine Orange; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Chick Embryo; Em | 2022 |
Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Prot | 2021 |
Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model.
Topics: Acridine Orange; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cu | 2013 |
The value of cell cycle analysis by propidium-iodine staining of CD56+ cells in pediatric brain tumors.
Topics: Adolescent; Brain Neoplasms; CD56 Antigen; Cell Cycle; Cell Division; Child; Child, Preschool; DNA, | 2015 |
Pro-apoptotic effect of methylguanidine on hydrogen peroxide-treated rat glioma cell line.
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Blotting, Western; Br | 2010 |
Lipid biomarkers of glioma cell growth arrest and cell death detected by 1 H magic angle spinning MRS.
Topics: Animals; Annexin A5; Biomarkers, Tumor; Brain Neoplasms; Cell Cycle; Cell Death; Cell Line, Tumor; C | 2012 |
Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death.
Topics: Annexin A5; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Brain | 2005 |
Intranuclear microtubules are hallmarks of an unusual form of cell death in cisplatin-treated C6 glioma cells.
Topics: Actin Cytoskeleton; Annexin A5; Antineoplastic Agents; Brain Neoplasms; Cell Cycle; Cell Death; Cell | 2006 |
Selective cytotoxicity of indomethacin and indomethacin ethyl ester-loaded nanocapsules against glioma cell lines: an in vitro study.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Brain Neoplasms; Cell Count | 2008 |
Radiation-induced changes in nucleoid halo diameters of aerobic and hypoxic SF-126 human brain tumor cells.
Topics: Aerobiosis; Brain; Brain Neoplasms; Cell Hypoxia; Cell Survival; DNA Damage; DNA, Neoplasm; DNA, Sup | 1995 |
Prediction of drug cytotoxicity in 9L rat brain tumor by using flow cytometry with a deoxyribonucleic acid-binding dye.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; DNA, Neoplasm; Drug Resistance, Neoplasm | 1997 |
Ploidy and proliferative activity of human brain tumors. A flow cytofluorometric study.
Topics: Adolescent; Adult; Aged; Aneuploidy; Brain Neoplasms; DNA, Neoplasm; Evaluation Studies as Topic; Fe | 1987 |