propidium has been researched along with Brain Ischemia in 14 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This protocol describes a model of cerebral ischemia based on organotypic hippocampal slice cultures and quantitative assessment of cell death by use of propidium iodide and image analysis." | 3.70 | A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence. ( Haug, FM; Laake, JH; Ottersen, OP; Wieloch, T, 1999) |
| "Neurodegenerative disorders are subjects of intense scrutiny in biomedical research because of their often-debilitating effects." | 2.44 | The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures. ( Cui, H; Lau, AC; Tymianski, M, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pamenter, ME | 1 |
| Perkins, GA | 1 |
| Gu, XQ | 1 |
| Ellisman, MH | 1 |
| Haddad, GG | 1 |
| Beraki, S | 1 |
| Litrus, L | 1 |
| Soriano, L | 1 |
| Monbureau, M | 1 |
| To, LK | 1 |
| Braithwaite, SP | 1 |
| Nikolich, K | 1 |
| Urfer, R | 1 |
| Oksenberg, D | 1 |
| Shamloo, M | 1 |
| Scartabelli, T | 1 |
| Gerace, E | 1 |
| Landucci, E | 1 |
| Moroni, F | 1 |
| Pellegrini-Giampietro, DE | 1 |
| Wilson, BC | 1 |
| Rappaport, R | 1 |
| Pugliese, AM | 1 |
| Traini, C | 1 |
| Cipriani, S | 1 |
| Gianfriddo, M | 1 |
| Mello, T | 1 |
| Giovannini, MG | 1 |
| Galli, A | 1 |
| Pedata, F | 1 |
| Bahmani, P | 1 |
| Schellenberger, E | 1 |
| Klohs, J | 1 |
| Steinbrink, J | 1 |
| Cordell, R | 1 |
| Zille, M | 1 |
| Müller, J | 1 |
| Harhausen, D | 1 |
| Hofstra, L | 1 |
| Reutelingsperger, C | 1 |
| Farr, TD | 1 |
| Dirnagl, U | 1 |
| Wunder, A | 1 |
| Cheng, Z | 1 |
| He, W | 1 |
| Zhou, X | 1 |
| Lv, Q | 1 |
| Xu, X | 1 |
| Yang, S | 1 |
| Zhao, C | 1 |
| Guo, L | 1 |
| Hassen, GW | 1 |
| Tian, D | 1 |
| Ding, D | 1 |
| Bergold, PJ | 1 |
| Fogal, B | 1 |
| Hewett, JA | 1 |
| Hewett, SJ | 1 |
| Skibo, GG | 1 |
| Lushnikova, IV | 1 |
| Voronin, KY | 1 |
| Dmitrieva, O | 1 |
| Novikova, T | 1 |
| Klementiev, B | 1 |
| Vaudano, E | 1 |
| Berezin, VA | 1 |
| Bock, E | 1 |
| Montero, M | 1 |
| Poulsen, FR | 1 |
| Noraberg, J | 1 |
| Kirkeby, A | 1 |
| van Beek, J | 1 |
| Leist, M | 1 |
| Zimmer, J | 2 |
| Lau, AC | 1 |
| Cui, H | 1 |
| Tymianski, M | 1 |
| Laake, JH | 1 |
| Haug, FM | 1 |
| Wieloch, T | 1 |
| Ottersen, OP | 1 |
| Bonde, C | 1 |
| Kristensen, BW | 1 |
| Blaabjerg, M | 1 |
| Johansen, TE | 1 |
| Meyer, M | 1 |
1 review available for propidium and Brain Ischemia
| Article | Year |
|---|---|
The use of propidium iodide to assess excitotoxic neuronal death in primary mixed cortical cultures.
Topics: Acute Disease; Animals; Benzimidazoles; Brain Ischemia; Cell Death; Cells, Cultured; Cerebral Cortex | 2007 |
13 other studies available for propidium and Brain Ischemia
| Article | Year |
|---|---|
DIDS (4,4-diisothiocyanatostilbenedisulphonic acid) induces apoptotic cell death in a hippocampal neuronal cell line and is not neuroprotective against ischemic stress.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Animals; Apoptosis; Biolog | 2013 |
A pharmacological screening approach for discovery of neuroprotective compounds in ischemic stroke.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 1; Analysis of Variance; Brain Ischemia; Carbenoxolone; Dr | 2013 |
Neuroprotection by group I mGlu receptors in a rat hippocampal slice model of cerebral ischemia is associated with the PI3K-Akt signaling pathway: a novel postconditioning strategy?
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Ischemia; Disease Models, Animal; Dose-Respon | 2008 |
An in vitro study of the protective effect of relaxin on brain tissue under ischemic stress.
Topics: Animals; Animals, Newborn; Brain; Brain Ischemia; Cell Death; Disease Models, Animal; In Vitro Techn | 2009 |
The adenosine A2A receptor antagonist ZM241385 enhances neuronal survival after oxygen-glucose deprivation in rat CA1 hippocampal slices.
Topics: Adenosine; Adenosine A2 Receptor Antagonists; Animals; Astrocytes; Blotting, Western; Brain Ischemia | 2009 |
Visualization of cell death in mice with focal cerebral ischemia using fluorescent annexin A5, propidium iodide, and TUNEL staining.
Topics: Animals; Annexin A5; Biomarkers; Brain Ischemia; Carbocyanines; Cell Death; Fluorescent Dyes; In Sit | 2011 |
Cordycepin protects against cerebral ischemia/reperfusion injury in vivo and in vitro.
Topics: Animals; Brain Ischemia; Cell Count; Deoxyadenosines; Excitatory Amino Acids; Glucose; Hippocampus; | 2011 |
A new model of ischemic preconditioning using young adult hippocampal slice cultures.
Topics: Adenosine Triphosphate; Animals; Antibodies; Brain Ischemia; Diffusion Chambers, Culture; DNA-Bindin | 2004 |
Interleukin-1beta potentiates neuronal injury in a variety of injury models involving energy deprivation.
Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Ischemia; Cell Count; Cell Death; Cells, Cult | 2005 |
A synthetic NCAM-derived peptide, FGL, protects hippocampal neurons from ischemic insult both in vitro and in vivo.
Topics: Animals; Animals, Newborn; Brain Ischemia; Cell Count; Cells, Cultured; Drug Interactions; Glucose; | 2005 |
Comparison of neuroprotective effects of erythropoietin (EPO) and carbamylerythropoietin (CEPO) against ischemia-like oxygen-glucose deprivation (OGD) and NMDA excitotoxicity in mouse hippocampal slice cultures.
Topics: Animals; Animals, Newborn; Brain Ischemia; Calpain; Coloring Agents; Erythropoietin; Excitatory Amin | 2007 |
A simple in vitro model of ischemia based on hippocampal slice cultures and propidium iodide fluorescence.
Topics: Animals; Brain Ischemia; Cell Death; Cell Hypoxia; Excitatory Amino Acid Antagonists; Fluorescent Dy | 1999 |
GDNF and neublastin protect against NMDA-induced excitotoxicity in hippocampal slice cultures.
Topics: Animals; Brain Ischemia; Cell Death; Cells, Cultured; Culture Media, Conditioned; Glial Cell Line-De | 2000 |