propidium has been researched along with Atrial Fibrillation in 1 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propidium iodide-uptake was sensitive to [Ca2+]o and the hemichannel blockers, carbenoxolone, flufenamic acid and mefloquine, but was not affected by the pannexin 1 channel blocking agent, probenecid, indicating that uptake is most likely mediated via connexin hemichannels." | 1.40 | Atrial fibrillation-linked germline GJA5/connexin40 mutants showed an increased hemichannel function. ( Bai, D; Hills, MD; Sun, Y; Tong, X; Ye, WG, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sun, Y | 1 |
| Hills, MD | 1 |
| Ye, WG | 1 |
| Tong, X | 1 |
| Bai, D | 1 |
1 other study available for propidium and Atrial Fibrillation
| Article | Year |
|---|---|
Atrial fibrillation-linked germline GJA5/connexin40 mutants showed an increased hemichannel function.
Topics: Animals; Atrial Fibrillation; Calcium; Carbenoxolone; Cations, Divalent; Connexins; Gap Junction alp | 2014 |