Page last updated: 2024-11-03

propidium and Ataxia Telangiectasia

propidium has been researched along with Ataxia Telangiectasia in 3 studies

Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pollard, JM1
Reboucas, JS1
Durazo, A1
Kos, I1
Fike, F1
Panni, M1
Gralla, EB1
Valentine, JS1
Batinic-Haberle, I1
Gatti, RA1
Djuzenova, CS1
Flentje, M1
Taylor, YC1
Duncan, PG1
Zhang, X1
Wright, WD1

Other Studies

3 other studies available for propidium and Ataxia Telangiectasia

ArticleYear
Radioprotective effects of manganese-containing superoxide dismutase mimics on ataxia-telangiectasia cells.
    Free radical biology & medicine, 2009, Aug-01, Volume: 47, Issue:3

    Topics: Annexin A5; Antioxidants; Apoptosis; Ataxia Telangiectasia; Biomimetic Materials; Cell Separation; C

2009
Light scatter and DNA accessibility to propidium iodide of ataxia telangiectasia and fanconi anemia cells.
    Biochemical and biophysical research communications, 2001, Aug-17, Volume: 286, Issue:2

    Topics: Ataxia Telangiectasia; Cell Nucleus; Cells, Cultured; Chromatin; Coloring Agents; DNA; Fanconi Anemi

2001
Differences in the DNA supercoiling response of irradiated cell lines from ataxia-telangiectasia versus unaffected individuals.
    International journal of radiation biology, 1991, Volume: 59, Issue:2

    Topics: Ataxia Telangiectasia; Cell Line; Cell Survival; DNA Damage; DNA, Superhelical; Dose-Response Relati

1991