propidium has been researched along with Astrocytoma, Grade IV in 7 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The sanguinarine treatment induced the proteolytic activation of caspases and ICAD/DFF45, which was associated with the modulation of the Bcl-2 family, concomitant degradation of poly(ADP ribose) polymerase and phospholipase C-gamma1 protein, and DNA fragmentation." | 5.34 | Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. ( Choi, BT; Choi, YH; Han, MH; Kim, GY; Kim, SO; Kwon, TK; Lee, WH, 2007) |
| " Previous results with the preclinical GL261 glioblastoma (GB) showed that combination treatment of temozolomide (TMZ) + CX-4945 (protein kinase CK2 inhibitor) outperformed single treatments, provided an immune-friendly schedule was followed." | 4.02 | Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells. ( Arús, C; Candiota, AP; Martínez-Escardó, L; Villamañan, L; Yuste, VJ, 2021) |
| "The human colon adenocarcinoma cell line WiDr was tested for combinations with camptothecin, cisplatin, gemcitabine and paclitaxel." | 3.79 | Comparison of the effects of photon versus carbon ion irradiation when combined with chemotherapy in vitro. ( Brons, S; Combs, SE; Debus, J; Haberer, T; Schlaich, F; Weber, KJ, 2013) |
| "The sanguinarine treatment induced the proteolytic activation of caspases and ICAD/DFF45, which was associated with the modulation of the Bcl-2 family, concomitant degradation of poly(ADP ribose) polymerase and phospholipase C-gamma1 protein, and DNA fragmentation." | 1.34 | Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. ( Choi, BT; Choi, YH; Han, MH; Kim, GY; Kim, SO; Kwon, TK; Lee, WH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Kadhim, ZA | 1 |
| Sulaiman, GM | 1 |
| Al-Shammari, AM | 1 |
| Khan, RA | 1 |
| Al Rugaie, O | 1 |
| Mohammed, HA | 1 |
| Villamañan, L | 1 |
| Martínez-Escardó, L | 1 |
| Arús, C | 1 |
| Yuste, VJ | 1 |
| Candiota, AP | 1 |
| Dilnawaz, F | 1 |
| Sahoo, SK | 1 |
| Schlaich, F | 1 |
| Brons, S | 1 |
| Haberer, T | 1 |
| Debus, J | 1 |
| Combs, SE | 1 |
| Weber, KJ | 1 |
| Chen, GG | 1 |
| Sin, FL | 1 |
| Leung, BC | 1 |
| Ng, HK | 1 |
| Poon, WS | 1 |
| Han, MH | 1 |
| Kim, SO | 1 |
| Kim, GY | 1 |
| Kwon, TK | 1 |
| Choi, BT | 1 |
| Lee, WH | 1 |
| Choi, YH | 1 |
| Hussaini, IM | 1 |
| Carpenter, JE | 1 |
| Redpath, GT | 1 |
| Sando, JJ | 1 |
| Shaffrey, ME | 1 |
| Vandenberg, SR | 1 |
7 other studies available for propidium and Astrocytoma, Grade IV
| Article | Year |
|---|---|
Oncolytic Newcastle Disease Virus Co-Delivered with Modified PLGA Nanoparticles Encapsulating Temozolomide against Glioblastoma Cells: Developing an Effective Treatment Strategy.
Topics: Acridine Orange; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Chick Embryo; Em | 2022 |
Successful Partnerships: Exploring the Potential of Immunogenic Signals Triggered by TMZ, CX-4945, and Combined Treatment in GL261 Glioblastoma Cells.
Topics: Adenosine Triphosphate; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Prot | 2021 |
Enhanced accumulation of curcumin and temozolomide loaded magnetic nanoparticles executes profound cytotoxic effect in glioblastoma spheroid model.
Topics: Acridine Orange; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Cu | 2013 |
Comparison of the effects of photon versus carbon ion irradiation when combined with chemotherapy in vitro.
Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Camptothecin; Carbon; Cel | 2013 |
Glioblastoma cells deficient in DNA-dependent protein kinase are resistant to cell death.
Topics: Annexin A5; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Brain | 2005 |
Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt.
Topics: Alkaloids; Animals; Annexin A5; Apoptosis; Benzophenanthridines; Blotting, Western; Caspases; Cell L | 2007 |
Protein kinase C-eta regulates resistance to UV- and gamma-irradiation-induced apoptosis in glioblastoma cells by preventing caspase-9 activation.
Topics: Apoptosis; Astrocytes; Caspase 9; Caspases; Coloring Agents; DNA; Enzyme Activation; Gamma Rays; Gli | 2002 |