propidium has been researched along with Amyotrophic Lateral Sclerosis in 3 studies
Propidium: Quaternary ammonium analog of ethidium; an intercalating dye with a specific affinity to certain forms of DNA and, used as diiodide, to separate them in density gradients; also forms fluorescent complexes with cholinesterase which it inhibits.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Green, KM | 1 |
| Sheth, UJ | 1 |
| Flores, BN | 1 |
| Wright, SE | 1 |
| Sutter, AB | 1 |
| Kearse, MG | 1 |
| Barmada, SJ | 1 |
| Ivanova, MI | 1 |
| Todd, PK | 1 |
| Wang, J | 1 |
| Zhang, Y | 1 |
| Tang, L | 1 |
| Zhang, N | 1 |
| Fan, D | 1 |
| Li, PA | 1 |
| He, Q | 1 |
| Cao, T | 1 |
| Yong, G | 1 |
| Szauter, KM | 1 |
| Fong, KS | 1 |
| Karlsson, J | 1 |
| Keep, MF | 1 |
| Csiszar, K | 1 |
3 other studies available for propidium and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation.
Topics: Amyotrophic Lateral Sclerosis; Animals; Ataxia; Azepines; Cells, Cultured; Circular Dichroism; DNA R | 2019 |
Protective effects of resveratrol through the up-regulation of SIRT1 expression in the mutant hSOD1-G93A-bearing motor neuron-like cell culture model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Annexin A5; Blotting, Western; Cell Death; Cell Survival; Cells, Cult | 2011 |
Up-regulation and altered distribution of lysyl oxidase in the central nervous system of mutant SOD1 transgenic mouse model of amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Blotting, Western; Central Nervous System; Cytoplasm; Diseas | 2004 |