Page last updated: 2024-11-03

propentofylline and Pick Disease of the Brain

propentofylline has been researched along with Pick Disease of the Brain in 1 studies

Pick Disease of the Brain: A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)

Research Excerpts

ExcerptRelevanceReference
"Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase."8.82Propentofylline for dementia. ( Frampton, M; Harvey, RJ; Kirchner, V, 2003)
"Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase."4.82Propentofylline for dementia. ( Frampton, M; Harvey, RJ; Kirchner, V, 2003)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Frampton, M1
Harvey, RJ1
Kirchner, V1

Reviews

1 review available for propentofylline and Pick Disease of the Brain

ArticleYear
Propentofylline for dementia.
    The Cochrane database of systematic reviews, 2003, Issue:2

    Topics: Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Neuroprotective Agents; Pick Disease

2003