propentofylline has been researched along with Ischemic Attack, Transient in 14 studies
Ischemic Attack, Transient: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propentofylline treatment resulted in a statistically significant decrease in infarct volume when an infusion dose of 6 mg/kg per h was initiated at 30 min or when a bolus of 3 mg/kg plus an infusion dose was initiated at 1 h but not 3 h post ischemia." | 1.30 | Temporal dependent neuroprotection with propentofylline (HWA 285) in a temporary focal ischemia model. ( Chmielewski, PA; Johnson, MP; McCarty, DR, 1998) |
| "Propentofylline (HWA285) has been reported to protect neuronal cells through the inhibition of glutamate release during transient ischemia." | 1.29 | Propentofylline (HWA285) inhibits the release of dopamine during transient ischemia and modulates its metabolism in rat striatum. ( Kawase, T; Mitani, S; Ogino, M; Saito, R; Shimizu, K; Toya, S; Yamaguchi, N, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (21.43) | 18.7374 |
| 1990's | 10 (71.43) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, M | 1 |
| Bai, X | 1 |
| Li, T | 1 |
| Chen, F | 1 |
| Dong, Q | 1 |
| Zhao, Y | 1 |
| Liu, X | 1 |
| Stanimirovic, DB | 1 |
| Micic, DV | 2 |
| Markovic, M | 1 |
| Spatz, M | 2 |
| Mrsulja, BB | 2 |
| McRae, A | 1 |
| Rudolphi, KA | 1 |
| Schubert, P | 3 |
| Kano, T | 1 |
| Katayama, Y | 1 |
| Kawamata, T | 1 |
| Hirota, H | 1 |
| Tsubokawa, T | 1 |
| Shimizu, K | 1 |
| Ogino, M | 1 |
| Yamaguchi, N | 1 |
| Mitani, S | 1 |
| Saito, R | 1 |
| Kawase, T | 1 |
| Toya, S | 1 |
| Phillis, JW | 1 |
| O'Regan, MH | 1 |
| Johnson, MP | 1 |
| McCarty, DR | 1 |
| Chmielewski, PA | 1 |
| Miyashita, K | 1 |
| Nakajima, T | 1 |
| Ishikawa, A | 1 |
| Miyatake, T | 1 |
| Hirata, H | 1 |
| Ogawa, N | 1 |
| Haba, K | 1 |
| Asanuma, M | 1 |
| Chou, H | 1 |
| Mori, A | 1 |
| Stanimirović, D | 1 |
| Dux, E | 1 |
| Fastbom, J | 1 |
| Ungerstedt, U | 1 |
| Rudolphi, K | 2 |
| Fredholm, BB | 1 |
| DeLeo, J | 2 |
| Toth, L | 1 |
| Kreutzberg, GW | 2 |
| Sasaki, M | 1 |
| Naritomi, H | 1 |
| Kanashiro, M | 1 |
| Nishimura, H | 1 |
| Sawada, T | 1 |
14 other studies available for propentofylline and Ischemic Attack, Transient
| Article | Year |
|---|---|
Decreased extracellular adenosine levels lead to loss of hypoxia-induced neuroprotection after repeated episodes of exposure to hypoxia.
Topics: 5'-Nucleotidase; Adenosine; Animals; Antigens, CD; Apyrase; Cerebrovascular Circulation; Equilibrati | 2013 |
'Therapeutic window's for multiple drug treatment of experimental cerebral ischemia in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Animals; Drug Therapy, Combination; Gerbillinae; Ischemic Attack, Trans | 1994 |
Propentosylline depresses amyloid and Alzheimer's CSF microglial antigens after ischaemia.
Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Antigen-Antibody Reactions; Antigens; Ce | 1994 |
Propentofylline administered by microdialysis attenuates ischemia-induced hippocampal damage but not excitatory amino acid release in gerbils.
Topics: Amino Acids; Animals; Cell Survival; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Microdial | 1994 |
Propentofylline (HWA285) inhibits the release of dopamine during transient ischemia and modulates its metabolism in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Ulcer Agents; Corpus Striatum; Dopamine; Homovanillic | 1993 |
Effects of an inhibitor of adenosine deaminase, deoxycoformycin, and of nucleoside transport, propentofylline, on post-ischemic recovery of adenine nucleotides in rat brain.
Topics: Adenine Nucleotides; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Diphosphate; Adenosine Mon | 1996 |
Temporal dependent neuroprotection with propentofylline (HWA 285) in a temporary focal ischemia model.
Topics: Animals; Blood Gas Analysis; Blood Glucose; Brain; Cerebral Infarction; Ischemic Attack, Transient; | 1998 |
An adenosine uptake blocker, propentofylline, reduces glutamate release in gerbil hippocampus following transient forebrain ischemia.
Topics: Adenosine; Amino Acids; Animals; Gerbillinae; Glutamates; Glutamic Acid; Glycine; Hippocampus; Ische | 1992 |
Effect of propentofylline on ischemia-induced loss of muscarinic cholinergic receptor binding in the gerbil hippocampus.
Topics: Animals; Anti-Ulcer Agents; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Kinetics; Pirenzep | 1992 |
Excitatory amino acid receptors, oxido-reductive processes and brain oedema following transient ischaemia in gerbils.
Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Animals; Anions; Brain Edema; Female; Gerbillinae; Ischemi | 1990 |
Protective effect of adenosine and a novel xanthine derivative propentofylline on the cell damage after bilateral carotid occlusion in the gerbil hippocampus.
Topics: Adenosine; Animals; Gerbillinae; Ischemic Attack, Transient; Male; Purinergic Antagonists; Receptors | 1990 |
Ischemia-induced neuronal cell death, calcium accumulation, and glial response in the hippocampus of the Mongolian gerbil and protection by propentofylline (HWA 285).
Topics: Animals; Calcium; Cell Survival; Gerbillinae; Glial Fibrillary Acidic Protein; Hippocampus; Histocyt | 1987 |
Effects of propentofylline on energy metabolism of the ischemic brain studied by in vivo 31P nuclear magnetic resonance spectroscopy.
Topics: Adenosine Triphosphate; Animals; Blood Gas Analysis; Blood Pressure; Body Water; Brain Chemistry; Ca | 1989 |
Propentofylline (HWA 285) protects hippocampal neurons of Mongolian gerbils against ischemic damage in the presence of an adenosine antagonist.
Topics: Adenosine; Animals; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Pyramidal T | 1988 |