propentofylline has been researched along with Glioma in 4 studies
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the previous study, we have shown that propentofylline (PPF) could induce the cellular differentiation and apoptosis-related growth regression in the human glioma cell lines." | 7.70 | [Neural protective agents, propentofylline (PPF) could induce apoptotic cell death in the human glioma cells: analysis of Bcl-2 and Bax alpha/Bax beta expressions]. ( Chiba, S; Hashimoto, I; Ide, W; Ikeda, M; Kamada, H; Matsumoto, A; Murakami, H; Ogata, A; Oshima, Y; Satone, A; Ukita, H; Yamaguchi, H, 1998) |
| "Propentofylline (PPF) is a xanthine derivative and it has been reported that PPF stimulated the synthesis/secretion of nerve growth factor (NGF) by cultured astroglial cells." | 5.30 | [Induction of apoptosis through NGF/p75NTR in human glioma cells treated with propentofylline]. ( Chiba, S; Hashimoto, I; Ide, W; Ikeda, M; Kamada, H; Matsumoto, A; Murakami, H; Ogata, A; Oshima, Y; Satone, A; Ukita, H; Yamaguchi, H, 1998) |
| "Propentofylline (PPF) has been reported to stimulate the synthesis/secretion of nerve growth factor (NGF) by cultured mouse astroglial cells." | 5.29 | [Up-regulation of NGF, trkA, Fas, down-regulation of bcl-2, and induction of apoptosis by propentofylline in human glioma cell lines]. ( Hashimoto, I; Ide, W; Ikeda, M; Kamada, H; Matsumoto, A; Murakami, H; Satone, A; Ukita, H; Yamaguchi, H, 1996) |
| "In the previous study, we have shown that propentofylline (PPF) could induce the cellular differentiation and apoptosis-related growth regression in the human glioma cell lines." | 3.70 | [Neural protective agents, propentofylline (PPF) could induce apoptotic cell death in the human glioma cells: analysis of Bcl-2 and Bax alpha/Bax beta expressions]. ( Chiba, S; Hashimoto, I; Ide, W; Ikeda, M; Kamada, H; Matsumoto, A; Murakami, H; Ogata, A; Oshima, Y; Satone, A; Ukita, H; Yamaguchi, H, 1998) |
| "Propentofylline (PPF) is a xanthine derivative and it has been reported that PPF stimulated the synthesis/secretion of nerve growth factor (NGF) by cultured astroglial cells." | 1.30 | [Induction of apoptosis through NGF/p75NTR in human glioma cells treated with propentofylline]. ( Chiba, S; Hashimoto, I; Ide, W; Ikeda, M; Kamada, H; Matsumoto, A; Murakami, H; Ogata, A; Oshima, Y; Satone, A; Ukita, H; Yamaguchi, H, 1998) |
| "Propentofylline (PPF) has been reported to stimulate the synthesis/secretion of nerve growth factor (NGF) by cultured mouse astroglial cells." | 1.29 | [Up-regulation of NGF, trkA, Fas, down-regulation of bcl-2, and induction of apoptosis by propentofylline in human glioma cell lines]. ( Hashimoto, I; Ide, W; Ikeda, M; Kamada, H; Matsumoto, A; Murakami, H; Satone, A; Ukita, H; Yamaguchi, H, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobs, VL | 1 |
| De Leo, JA | 1 |
| Kamada, H | 3 |
| Murakami, H | 3 |
| Satone, A | 3 |
| Ikeda, M | 3 |
| Yamaguchi, H | 3 |
| Matsumoto, A | 3 |
| Ide, W | 3 |
| Hashimoto, I | 3 |
| Ukita, H | 3 |
| Chiba, S | 2 |
| Oshima, Y | 2 |
| Ogata, A | 2 |
4 other studies available for propentofylline and Glioma
| Article | Year |
|---|---|
Increased glutamate uptake in astrocytes via propentofylline results in increased tumor cell apoptosis using the CNS-1 glioma model.
Topics: Animals; Animals, Newborn; Annexin A5; Apoptosis; Astrocytes; Cell Line, Tumor; Cell Proliferation; | 2013 |
[Up-regulation of NGF, trkA, Fas, down-regulation of bcl-2, and induction of apoptosis by propentofylline in human glioma cell lines].
Topics: Animals; Apoptosis; Down-Regulation; fas Receptor; Glioma; Humans; Mice; Nerve Growth Factors; Polym | 1996 |
[Neural protective agents, propentofylline (PPF) could induce apoptotic cell death in the human glioma cells: analysis of Bcl-2 and Bax alpha/Bax beta expressions].
Topics: Apoptosis; bcl-2-Associated X Protein; Cell Division; Cell Line; Glioma; Humans; Proto-Oncogene Prot | 1998 |
[Induction of apoptosis through NGF/p75NTR in human glioma cells treated with propentofylline].
Topics: Apoptosis; Brain Neoplasms; Carrier Proteins; Glioma; Humans; Nerve Growth Factors; Nerve Tissue Pro | 1998 |