propentofylline has been researched along with Disease Models, Animal in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (20.83) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 14 (58.33) | 24.3611 |
| 2020's | 1 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Constandil, L; Galleguillos, D; Hernández, A; Marcos, JL; Pelissier, T; Velásquez, L; Villanueva, L | 1 |
| Alves-Filho, JC; Cecilio, NT; Cunha, FQ; Cunha, TM; Davoli-Ferreira, M; Ferreira, DW; Fonseca, MM; Guimaraes, RM; Kusuda, R; Lopes, AH; Nachbur, U; Santa-Cecília, FV; Souza, GR; Teixeira, MM; Zamboni, DS | 1 |
| Chen, J; Liu, Z; Miao, X; Sun, Y; Tao, Y; Wu, F; Yu, W | 1 |
| Bondan, EF; Castro Poppe, S; Martha Bernardi, M; Martins, Mde F; Menezes Baliellas, DE; Monteiro Gimenez, CF | 1 |
| Ellis, A; Falci, S; Favret, J; Johnson, KW; Maier, SF; Rice, KC; Watkins, LR; Wieseler, J | 1 |
| Bernardi, MM; Bondan, EF; Martins, Mde F | 1 |
| Bernardi, MM; Bondan, EF; Cardoso, CV; Dossa, PD; Martins, JL; Martins, MF; Viebig, LB | 1 |
| Bernardi, MM; Bondan, EF; Cabral, D; Coelho, CP; Galvão, MC; Kirsten, TB; Martins, MF; Moraes, MM; Queiroz-Hazarbassanov, N | 1 |
| Gwak, YS; Hulsebosch, CE; Unabia, GC | 1 |
| Chessell, IP; Curnow, SJ; Delaney, SA; Hughes, JP; Salmon, M; Smith, CG; Whitehead, KJ | 1 |
| Cao, HQ; Chang, XY; Chu, YX; Liu, MJ; Wang, LN; Xu, QN; Yang, JP; Yao, M | 1 |
| De Leo, JA; Jacobs, VL; Landry, RP; Liu, Y; Romero-Sandoval, EA | 1 |
| Liu, Y; Liu, Z; Ren, W; Shi, M; Wei, C; Wu, X; Yang, M; Zhang, X | 1 |
| Bourgeais, L; Cazorla, M; Constandil, L; Goich, M; Hamon, M; Hernández, A; Pelissier, T; Villanueva, L | 1 |
| Chauhan, NB; Feinstein, DL; Siegel, GJ | 1 |
| Blackburn-Munro, G; Delaney, A; Dickinson, T; Fleetwood-Walker, SM; Garry, EM; Mitchell, R; Moss, A; Nakalembe, I; Robberecht, P; Robertson, DC; Rosie, R | 1 |
| Fitzgibbons, JC; Gidday, JM; Kraujalis, MJ; Park, TS; Shah, AR | 1 |
| Hasegawa, T; Nabeshima, T; Nitta, A | 1 |
| Furukawa, S; Hasegawa, T; Nabeshima, T; Nitta, A; Ogihara, Y; Onishi, J | 1 |
| Ling, EA; McRae, A; Rudolphi, K; Schubert, P | 1 |
| DeLeo, JA; Schubert, P; Sweitzer, SM | 1 |
| Kolvenbach, R; Nemat, AT; Sandmann, W | 1 |
24 other study(ies) available for propentofylline and Disease Models, Animal
| Article | Year |
|---|---|
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Role of the spinal TrkB-NMDA receptor link in the BDNF-induced long-lasting mechanical hyperalgesia in the rat: A behavioural study.
Topics: Animals; Brain-Derived Neurotrophic Factor; Central Nervous System Sensitization; Disease Models, Animal; Hyperalgesia; Ketamine; Male; Neuroglia; Neuronal Plasticity; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Spinal Cord; Xanthines | 2017 |
The NOD2 signaling in peripheral macrophages contributes to neuropathic pain development.
Topics: Animals; Bone Marrow Transplantation; Carrageenan; Disease Models, Animal; Inflammation; Interleukin 1 Receptor Antagonist Protein; Macrophages; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Minocycline; Neuralgia; Neuroprotective Agents; Nod2 Signaling Adaptor Protein; Receptor-Interacting Protein Serine-Threonine Kinase 2; Receptor-Interacting Protein Serine-Threonine Kinases; Receptors, Tumor Necrosis Factor, Type I; RNA, Small Interfering; Signal Transduction; Toll-Like Receptor 4; Xanthines | 2019 |
Inhibition of GAP-43 by propentofylline in a rat model of neuropathic pain.
Topics: Animals; Astrocytes; Blotting, Western; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; GAP-43 Protein; Hyperalgesia; Male; Neuralgia; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Xanthines | 2013 |
Effects of propentofylline on CNS remyelination in the rat brainstem.
Topics: Animals; Brain Stem; Demyelinating Diseases; Disease Models, Animal; Humans; Male; Myelin Sheath; Oligodendroglia; Rats; Rats, Wistar; Schwann Cells; Xanthines | 2014 |
Systemic administration of propentofylline, ibudilast, and (+)-naltrexone each reverses mechanical allodynia in a novel rat model of central neuropathic pain.
Topics: Animals; Disease Models, Animal; Hyperalgesia; Male; Naltrexone; Narcotic Antagonists; Neuralgia; Neuroglia; Neuroprotective Agents; Phosphodiesterase Inhibitors; Pyridines; Radiculopathy; Rats; Rats, Sprague-Dawley; Xanthines | 2014 |
Propentofylline reverses delayed remyelination in streptozotocin-induced diabetic rats.
Topics: Animals; Astrocytes; Demyelinating Diseases; Diabetes Mellitus, Experimental; Disease Models, Animal; Ethidium; Macrophages; Male; Mesencephalon; Microscopy, Electron, Transmission; Myelin Sheath; Nerve Regeneration; Neuroprotective Agents; Pons; Rats, Wistar; Schwann Cells; Streptozocin; Xanthines | 2015 |
Propentofylline reduces glial scar development following gliotoxic damage in the rat brainstem.
Topics: Animals; Astrocytes; Brain Stem; Demyelinating Diseases; Disease Models, Animal; Ethidium; Glial Fibrillary Acidic Protein; Gliotoxin; Immunohistochemistry; Male; Neuroprotective Agents; Rats, Wistar; Reproducibility of Results; Time Factors; Treatment Outcome; Xanthines | 2016 |
Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway.
Topics: Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Body Weight; Brain-Derived Neurotrophic Factor; Depression; Depressive Disorder; Disease Models, Animal; Glial Fibrillary Acidic Protein; Illness Behavior; Immunohistochemistry; Lipopolysaccharides; Male; Photomicrography; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha; Xanthines | 2017 |
Activation of p-38alpha MAPK contributes to neuronal hyperexcitability in caudal regions remote from spinal cord injury.
Topics: Animals; Astrocytes; Disease Models, Animal; Enzyme Activation; Gliosis; Hyperalgesia; Male; Microglia; Neurons; Neurons, Afferent; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Rats; Rats, Sprague-Dawley; Sensory Receptor Cells; Spinal Cord; Spinal Cord Injuries; Treatment Outcome; Xanthines | 2009 |
Dynamic regulation of spinal pro-inflammatory cytokine release in the rat in vivo following peripheral nerve injury.
Topics: Afferent Pathways; Animals; Cytokines; Disease Models, Animal; Electric Stimulation; Interleukin-1beta; Interleukin-6; Male; Microdialysis; Neuroglia; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Spinal Cord; Trauma, Nervous System; Tumor Necrosis Factor-alpha; Xanthines | 2010 |
Antiallodynic effects of propentofylline Elicited by interrupting spinal glial function in a rat model of bone cancer pain.
Topics: Animals; Bone Neoplasms; Cytokines; Disease Models, Animal; Female; Neuroglia; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord; Xanthines | 2011 |
Propentofylline decreases tumor growth in a rodent model of glioblastoma multiforme by a direct mechanism on microglia.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Central Nervous System; Disease Models, Animal; Glioblastoma; Humans; Macrophages; Male; Matrix Metalloproteinase 9; Microglia; Neoplasm Invasiveness; Rats; Tumor Cells, Cultured; Tumor Microenvironment; Xanthines | 2012 |
Potentiation of synaptic strength and intrinsic excitability in the nucleus accumbens after 10 days of morphine withdrawal.
Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Amino Acids; Analysis of Variance; Animals; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Down-Regulation; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; In Vitro Techniques; Male; Morphine; Narcotics; Neurons; Neuroprotective Agents; Nucleus Accumbens; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Synapses; Xanthines | 2012 |
Cyclotraxin-B, a new TrkB antagonist, and glial blockade by propentofylline, equally prevent and reverse cold allodynia induced by BDNF or partial infraorbital nerve constriction in mice.
Topics: Analgesics; Animals; Brain-Derived Neurotrophic Factor; Central Nervous System Sensitization; Cold Temperature; Disease Models, Animal; Hyperalgesia; Male; Mice; Neuralgia; Neuroglia; Neuroprotective Agents; Peptides, Cyclic; Receptor, trkB; Trigeminal Neuralgia; Xanthines | 2012 |
Propentofylline attenuates tau hyperphosphorylation in Alzheimer's Swedish mutant model Tg2576.
Topics: Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Blotting, Western; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Neuroprotective Agents; Phosphorylation; Serine; tau Proteins; Xanthines | 2005 |
Activation of p38 and p42/44 MAP kinase in neuropathic pain: involvement of VPAC2 and NK2 receptors and mediation by spinal glia.
Topics: Animals; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Inflammation Mediators; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Neuralgia; Neuroglia; Neuroprotective Agents; p38 Mitogen-Activated Protein Kinases; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Phosphorylation; Physical Stimulation; Posterior Horn Cells; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-2; Receptors, Vasoactive Intestinal Peptide, Type II; Tumor Necrosis Factor-alpha; Xanthines | 2005 |
Reduction in cerebral ischemic injury in the newborn rat by potentiation of endogenous adenosine.
Topics: Adenosine; Animals; Animals, Newborn; Body Temperature; Brain; Brain Ischemia; Disease Models, Animal; Dizocilpine Maleate; Enzyme Inhibitors; Neuroprotective Agents; Organ Size; Pentostatin; Rats; Rats, Sprague-Dawley; Xanthines | 1995 |
Impairment of learning and memory and the accessory symptom in aged rat as senile dementia model (3): Oral administration of propentofylline produces recovery of reduced NGF content in the brain of aged rats.
Topics: Administration, Oral; Aging; Alzheimer Disease; Animals; Brain; Choline O-Acetyltransferase; Disease Models, Animal; Male; Nerve Growth Factors; Rats; Rats, Wistar; Xanthines | 1993 |
Propentofylline prevents neuronal dysfunction induced by infusion of anti-nerve growth factor antibody into the rat septum.
Topics: Administration, Intranasal; Animals; Anti-Ulcer Agents; Antibodies, Monoclonal; Choline O-Acetyltransferase; Cognition Disorders; Dementia; Disease Models, Animal; Hippocampus; Male; Maze Learning; Nasal Septum; Nerve Growth Factors; Rats; Rats, Wistar; Stimulation, Chemical; Xanthines | 1996 |
Properties of activated microglia and pharmacologic interference by propentofylline.
Topics: Adult; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Brain Ischemia; Cholinergic Fibers; Disease Models, Animal; Gerbillinae; Humans; Macrophage Activation; Microglia; Neuroprotective Agents; Prosencephalon; Rats; Xanthines | 1998 |
Propentofylline, a glial modulating agent, exhibits antiallodynic properties in a rat model of neuropathic pain.
Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Immunohistochemistry; Injections, Intraperitoneal; Injections, Spinal; Male; Neuroglia; Pain Measurement; Physical Stimulation; Rats; Rats, Sprague-Dawley; Somatoform Disorders; Spinal Cord; Spinal Nerves; Treatment Outcome; Xanthines | 2001 |
Disturbance of cerebral autoregulation after global ischemia and the stabilizing role of adenosine.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Homeostasis; Rats; Xanthines | 1992 |