propentofylline has been researched along with Dementia in 5 studies
Dementia: An acquired organic mental disorder with loss of intellectual abilities of sufficient severity to interfere with social or occupational functioning. The dysfunction is multifaceted and involves memory, behavior, personality, judgment, attention, spatial relations, language, abstract thought, and other executive functions. The intellectual decline is usually progressive, and initially spares the level of consciousness.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Over a 3-month period a multicenter, double-blind, placebo-controlled, parallel-group study was conducted in 190 patients with dementia to examine whether administration of the xanthine derivative propentofylline at 0." | 9.07 | Placebo-controlled trial of the xanthine derivative propentofylline in dementia. ( Maurer, I; Möller, HJ; Saletu, B, 1994) |
| "Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase." | 8.82 | Propentofylline for dementia. ( Frampton, M; Harvey, RJ; Kirchner, V, 2003) |
| " Over a 3-month period a multicenter, double-blind, placebo-controlled, parallel-group study was conducted in 190 patients with dementia to examine whether administration of the xanthine derivative propentofylline at 0." | 5.07 | Placebo-controlled trial of the xanthine derivative propentofylline in dementia. ( Maurer, I; Möller, HJ; Saletu, B, 1994) |
| "Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase." | 4.82 | Propentofylline for dementia. ( Frampton, M; Harvey, RJ; Kirchner, V, 2003) |
| " Plasma concentrations of cerebral metabolic activating drugs (bifemelane, indeloxazine and propentofylline) were studied in 68 patients (male 25, female 43) with dementia or other organic brain diseases." | 3.69 | A preliminary study on plasma concentrations of bifemelane, indeloxazine and propentofylline in aged patients with organic brain disorders. ( Arai, H; Inoue, R; Kimura, M; Minami, M; Noguchi, I; Suzuki, T; Takahashi, T, 1995) |
| "Propentofylline has potent stimulatory effects on NGF synthesis/secretion in mouse astrocytes in vitro." | 1.29 | Propentofylline prevents neuronal dysfunction induced by infusion of anti-nerve growth factor antibody into the rat septum. ( Furukawa, S; Hasegawa, T; Nabeshima, T; Nitta, A; Ogihara, Y; Onishi, J, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frampton, M | 1 |
| Harvey, RJ | 1 |
| Kirchner, V | 1 |
| Minami, M | 1 |
| Arai, H | 1 |
| Takahashi, T | 1 |
| Kimura, M | 1 |
| Noguchi, I | 1 |
| Suzuki, T | 1 |
| Inoue, R | 1 |
| Möller, HJ | 1 |
| Maurer, I | 1 |
| Saletu, B | 1 |
| Nitta, A | 1 |
| Ogihara, Y | 1 |
| Onishi, J | 1 |
| Hasegawa, T | 1 |
| Furukawa, S | 1 |
| Nabeshima, T | 1 |
1 review available for propentofylline and Dementia
| Article | Year |
|---|---|
Propentofylline for dementia.
Topics: Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Neuroprotective Agents; Pick Disease | 2003 |
1 trial available for propentofylline and Dementia
| Article | Year |
|---|---|
Placebo-controlled trial of the xanthine derivative propentofylline in dementia.
Topics: Aged; Anti-Ulcer Agents; Arousal; Cognition; Dementia; Double-Blind Method; Emotions; Female; Humans | 1994 |
3 other studies available for propentofylline and Dementia
| Article | Year |
|---|---|
A preliminary study on plasma concentrations of bifemelane, indeloxazine and propentofylline in aged patients with organic brain disorders.
Topics: Aged; Antidepressive Agents; Benzhydryl Compounds; Dementia; Female; Humans; Male; Morpholines; Xant | 1995 |
Propentofylline prevents neuronal dysfunction induced by infusion of anti-nerve growth factor antibody into the rat septum.
Topics: Administration, Intranasal; Animals; Anti-Ulcer Agents; Antibodies, Monoclonal; Choline O-Acetyltran | 1996 |
[Dementia-related diseases. Propentofyllin--a neuroprotective glia cell modulator].
Topics: Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Neuroglia; Xanthines | 1998 |