propentofylline has been researched along with Dementia, Vascular in 10 studies
Dementia, Vascular: An imprecise term referring to dementia associated with CEREBROVASCULAR DISORDERS, including CEREBRAL INFARCTION (single or multiple), and conditions associated with chronic BRAIN ISCHEMIA. Diffuse, cortical, and subcortical subtypes have been described. (From Gerontol Geriatr 1998 Feb;31(1):36-44)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase." | 8.82 | Propentofylline for dementia. ( Frampton, M; Harvey, RJ; Kirchner, V, 2003) |
| "Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase." | 4.82 | Propentofylline for dementia. ( Frampton, M; Harvey, RJ; Kirchner, V, 2003) |
| "Propentofylline was found to provide consistent improvements over placebo in efficacy assessments for both AD and VaD patients." | 2.40 | Propentofylline in the treatment of Alzheimer's disease and vascular dementia: a review of phase III trials. ( Erkinjuntti, T; Karlsson, I; Kittner, B; Marcusson, J; Roessner, M; Rother, M, 1998) |
| "In experimental models of vascular dementia and/or Alzheimer's disease it improves cognitive functions, inhibits inflammatory processes as well as excessive activation of microglia, formation of free radicals, cytocines and abnormal amyloid precursor proteins (APP)." | 2.40 | [New pharmacologic aspects in the neurologic profile of propentofylline (Karsivan ad us. vet.)]. ( Kapl, D; Rudolphi, KA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frampton, M | 1 |
| Harvey, RJ | 1 |
| Kirchner, V | 1 |
| Rother, M | 4 |
| Kittner, B | 6 |
| Rudolphi, K | 1 |
| Rössner, M | 2 |
| Labs, KH | 1 |
| Mielke, R | 2 |
| Ghaemi, M | 1 |
| Kessler, J | 1 |
| Szelies, B | 1 |
| Herholz, K | 1 |
| Heiss, WD | 1 |
| Erkinjuntti, T | 3 |
| Roessner, M | 1 |
| Marcusson, J | 1 |
| Karlsson, I | 1 |
| Möller, HJ | 1 |
| Rosenkranz, B | 1 |
| Kapl, D | 1 |
| Rudolphi, KA | 1 |
| De Deyn, PP | 1 |
| Ringheim, GE | 1 |
7 reviews available for propentofylline and Dementia, Vascular
| Article | Year |
|---|---|
Propentofylline for dementia.
Topics: Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Neuroprotective Agents; Pick Disease | 2003 |
HWA 285 (propentofylline)--a new compound for the treatment of both vascular dementia and dementia of the Alzheimer type.
Topics: Activities of Daily Living; Alzheimer Disease; Brain Ischemia; Clinical Trials as Topic; Dementia, V | 1996 |
Clinical trials in dementia with propentofylline.
Topics: Adenosine; Aged; Alzheimer Disease; Clinical Trials, Phase III as Topic; Dementia, Vascular; Double- | 1997 |
Propentofylline in the treatment of Alzheimer's disease and vascular dementia: a review of phase III trials.
Topics: Alzheimer Disease; Clinical Trials, Phase III as Topic; Dementia, Vascular; Humans; Neuroprotective | 1998 |
Propentofylline in the treatment of vascular dementia and Alzheimer-type dementia: overview of phase I and phase II clinical trials.
Topics: Aged; Alzheimer Disease; Brain; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topi | 1998 |
[New pharmacologic aspects in the neurologic profile of propentofylline (Karsivan ad us. vet.)].
Topics: Adenosine; Alzheimer Disease; Animals; Cerebrovascular Circulation; Cognition Disorders; Dementia, V | 1998 |
Glial modulating and neurotrophic properties of propentofylline and its application to Alzheimer's disease and vascular dementia.
Topics: Alzheimer Disease; Animals; Dementia, Vascular; Humans; Learning; Memory; Neuroglia; Neuroprotective | 2000 |
2 trials available for propentofylline and Dementia, Vascular
| Article | Year |
|---|---|
Propentofylline improves regional cerebral glucose metabolism and neuropsychologic performance in vascular dementia.
Topics: Aged; Anti-Ulcer Agents; Cerebral Cortex; Dementia, Vascular; Disease Progression; Female; Glucose; | 1996 |
Investigating the natural course and treatment of vascular dementia and Alzheimer's disease. Parallel study populations in two randomized, placebo-controlled trials.
Topics: Aged; Alzheimer Disease; Cognition; Dementia, Vascular; Disease Progression; Female; Humans; Male; N | 2000 |
1 other study available for propentofylline and Dementia, Vascular
| Article | Year |
|---|---|
[Dementia-related diseases. Propentofyllin--a neuroprotective glia cell modulator].
Topics: Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Neuroglia; Xanthines | 1998 |