propentofylline has been researched along with Cerebral Ischemia in 26 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "To assess the effect of intravenous or oral methylxanthines (pentoxifylline, propentofylline, or pentifylline) in patients with acute ischaemic stroke." | 8.82 | Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. ( Bath, PM; Bath-Hextall, FJ, 2004) |
| "The objective of this review was to assess the effect of intravenous or oral methylxanthines (pentoxifylline, propentofylline, or pentifylline) in patients with acute ischaemic stroke." | 8.80 | Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. ( Asplund, K; Bath, FJ; Bath, PM, 2000) |
| "The effect of propentofylline on mitochondrial respiratory activity was assessed in gerbils after 30 min of unilateral forebrain ischemia and 5 min of incomplete reperfusion." | 7.72 | Propentofylline rapidly normalizes mitochondrial respiration in a gerbil low flow unilateral forebrain ischemia. ( Pavlik, A; Turcani, M; Turcani, P, 2003) |
| " Propentofylline, an adenosine uptake and phosphodiesterase inhibitor, has been shown to be neuroprotective in various models of cerebral ischemia." | 7.71 | Effect of propentofylline on cerebral blood flow in a gerbil focal cerebral ischemia. ( Turcáni, P; Turèáni, M, 2001) |
| "1." | 6.39 | Propentofylline: a nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia. ( Fredholm, BB; Parkinson, FE; Rudolphi, KA, 1994) |
| "Posttreatment with propentofylline (0." | 5.29 | Antiischemic effects of propentofylline (HWA 285) against focal cerebral infarction in rats. ( Park, CK; Rudolphi, KA, 1994) |
| "To assess the effect of intravenous or oral methylxanthines (pentoxifylline, propentofylline, or pentifylline) in patients with acute ischaemic stroke." | 4.82 | Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. ( Bath, PM; Bath-Hextall, FJ, 2004) |
| "The objective of this review was to assess the effect of intravenous or oral methylxanthines (pentoxifylline, propentofylline, or pentifylline) in patients with acute ischaemic stroke." | 4.80 | Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke. ( Asplund, K; Bath, FJ; Bath, PM, 2000) |
| "The effect of propentofylline on mitochondrial respiratory activity was assessed in gerbils after 30 min of unilateral forebrain ischemia and 5 min of incomplete reperfusion." | 3.72 | Propentofylline rapidly normalizes mitochondrial respiration in a gerbil low flow unilateral forebrain ischemia. ( Pavlik, A; Turcani, M; Turcani, P, 2003) |
| " Propentofylline, an adenosine uptake and phosphodiesterase inhibitor, has been shown to be neuroprotective in various models of cerebral ischemia." | 3.71 | Effect of propentofylline on cerebral blood flow in a gerbil focal cerebral ischemia. ( Turcáni, P; Turèáni, M, 2001) |
| "The purpose of this study was to determine the effects of adenosine agonists and an antagonist on ischemia-induced extracellular glutamate concentrations in an animal model of transient cerebral ischemia using in vivo cerebral microdialysis." | 3.70 | Effects of adenosine agonists and an antagonist on excitatory transmitter release from the ischemic rabbit hippocampus. ( Martinez-Tica, JF; Zornow, MH, 2000) |
| " Recently, propentofylline, a xanthine derivative, has been shown to increase extracellular concentrations of adenosine in ischemic brain and to limit the extent of neuronal damage in experimental models of cerebral ischemia." | 3.68 | Inhibitory effects of propentofylline on [3H]adenosine influx. A study of three nucleoside transport systems. ( Cass, CE; Parkinson, FE; Paterson, AR; Young, JD, 1993) |
| "1." | 2.39 | Propentofylline: a nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia. ( Fredholm, BB; Parkinson, FE; Rudolphi, KA, 1994) |
| "Propentofylline was administered 24 hours after short preconditioning ischemia, and animals were subjected to 5-minute ischemia 24 hours thereafter." | 1.30 | Propentofylline potentiates induced ischemic tolerance in gerbil hippocampal neurons via adenosine receptor. ( Ide, T; Kawahara, N; Kawai, K; Kirino, T; Saito, N, 1998) |
| " In summary, the results demonstrated that chronic administration of PPF induced an enhancement in ATP concentration in adult rat hippocampus under conditions of long-term brain vessel occlusion." | 1.30 | Effect of propentofylline on hippocampal brain energy state and amyloid precursor protein concentration in a rat model of cerebral hypoperfusion. ( Bardenheuer, HJ; Martin, E; Plaschke, K, 1998) |
| "Posttreatment with propentofylline (0." | 1.29 | Antiischemic effects of propentofylline (HWA 285) against focal cerebral infarction in rats. ( Park, CK; Rudolphi, KA, 1994) |
| "Propentofylline pretreatment at a dose of 25 mg/kg p." | 1.29 | Effect of propentofylline on [3H]-leucine incorporation into protein of postischemic rat brain. ( Faberová, V; Fabianová, M; Machová, J; Noskovic, P, 1996) |
| " Determination of the dose-response relation revealed the optimal dose of HWA 285 to be 10 mg/kg i." | 1.27 | Protection against ischemic brain damage using propentofylline in gerbils. ( DeLeo, J; Kreutzberg, GW; Schubert, P, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.85) | 18.7374 |
| 1990's | 18 (69.23) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turcani, M | 1 |
| Pavlik, A | 1 |
| Turcani, P | 2 |
| Bath, PM | 2 |
| Bath-Hextall, FJ | 1 |
| Gidday, JM | 1 |
| Fitzgibbons, JC | 1 |
| Shah, AR | 1 |
| Kraujalis, MJ | 1 |
| Park, TS | 1 |
| Melaragno Filho, R | 1 |
| Park, CK | 1 |
| Rudolphi, KA | 3 |
| Parkinson, FE | 2 |
| Fredholm, BB | 2 |
| Paterson, AR | 1 |
| Young, JD | 1 |
| Cass, CE | 1 |
| Kolvenbach, R | 2 |
| Figge, C | 1 |
| Godehardt, E | 1 |
| Sandmann, W | 2 |
| Huber, M | 1 |
| Kittner, B | 2 |
| Hojer, C | 1 |
| Fink, GR | 1 |
| Neveling, M | 1 |
| Heiss, WD | 1 |
| Rother, M | 1 |
| Rudolphi, K | 3 |
| Rössner, M | 1 |
| Labs, KH | 1 |
| Matsumoto, K | 1 |
| Sakaki, T | 1 |
| Kohmura, E | 1 |
| Hayakawa, T | 1 |
| Yamada, K | 1 |
| Faberová, V | 1 |
| Fabianová, M | 1 |
| Noskovic, P | 1 |
| Machová, J | 1 |
| Kawahara, N | 1 |
| Ide, T | 1 |
| Saito, N | 1 |
| Kawai, K | 1 |
| Kirino, T | 1 |
| Plaschke, K | 3 |
| Bardenheuer, HJ | 3 |
| Weigand, MA | 2 |
| Martin, E | 3 |
| Hoyer, S | 1 |
| McRae, A | 2 |
| Ling, EA | 3 |
| Schubert, P | 2 |
| Wu, YP | 1 |
| Bath, FJ | 1 |
| Asplund, K | 1 |
| Martinez-Tica, JF | 1 |
| Zornow, MH | 1 |
| Turèáni, M | 1 |
| Ng, YK | 1 |
| Grant, M | 1 |
| Züchner, J | 1 |
| Nemat, AT | 1 |
| Kadoya, F | 1 |
| Hayashi, F | 1 |
| Senda, T | 1 |
| Yoshimura, Y | 1 |
| Imon, H | 1 |
| Arai, T | 1 |
| Andiné, P | 1 |
| Hagberg, H | 1 |
| DeLeo, J | 1 |
| Kreutzberg, GW | 1 |
5 reviews available for propentofylline and Cerebral Ischemia
| Article | Year |
|---|---|
Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke.
Topics: Brain Ischemia; Humans; Neuroprotective Agents; Pentoxifylline; Platelet Aggregation Inhibitors; Str | 2004 |
[The importance of clinical hemorheology in the study of cerebral blood flow in normal conditions and in cerebrovascular ischemia].
Topics: Ancrod; Animals; Blood Viscosity; Brain Ischemia; Cerebral Infarction; Cerebrovascular Circulation; | 1995 |
Propentofylline: a nucleoside transport inhibitor with neuroprotective effects in cerebral ischemia.
Topics: Adenosine; Animals; Biological Transport; Brain Ischemia; Cells, Cultured; Cerebrovascular Circulati | 1994 |
HWA 285 (propentofylline)--a new compound for the treatment of both vascular dementia and dementia of the Alzheimer type.
Topics: Activities of Daily Living; Alzheimer Disease; Brain Ischemia; Clinical Trials as Topic; Dementia, V | 1996 |
Pentoxifylline, propentofylline and pentifylline for acute ischaemic stroke.
Topics: Brain Ischemia; Humans; Neuroprotective Agents; Pentoxifylline; Platelet Aggregation Inhibitors; Str | 2000 |
1 trial available for propentofylline and Cerebral Ischemia
| Article | Year |
|---|---|
Effect of propentofylline on regional cerebral glucose metabolism in acute ischemic stroke.
Topics: Acute Disease; Aged; Aged, 80 and over; Brain; Brain Ischemia; Cerebrovascular Disorders; Double-Bli | 1993 |
20 other studies available for propentofylline and Cerebral Ischemia
| Article | Year |
|---|---|
Propentofylline rapidly normalizes mitochondrial respiration in a gerbil low flow unilateral forebrain ischemia.
Topics: Animals; Brain Ischemia; Cell Respiration; Cerebrovascular Circulation; Functional Laterality; Gerbi | 2003 |
Reduction in cerebral ischemic injury in the newborn rat by potentiation of endogenous adenosine.
Topics: Adenosine; Animals; Animals, Newborn; Body Temperature; Brain; Brain Ischemia; Disease Models, Anima | 1995 |
Antiischemic effects of propentofylline (HWA 285) against focal cerebral infarction in rats.
Topics: Adenosine; Animals; Behavior, Animal; Brain Ischemia; Cerebral Infarction; Male; Nervous System; Neu | 1994 |
Inhibitory effects of propentofylline on [3H]adenosine influx. A study of three nucleoside transport systems.
Topics: Adenosine; Animals; Biological Transport; Brain Ischemia; Cell Line; Mice; Rats; Thioinosine; Tritiu | 1993 |
Adenosine agonists and global cerebral ischaemia.
Topics: Adenosine; Animals; Brain; Brain Ischemia; Male; Rats; Rats, Wistar; Xanthines | 1993 |
Amelioration of ischemic brain damage by the preischemic administration of propentofylline (HWA285) in a rat focal ischemia.
Topics: Animals; Anti-Ulcer Agents; Brain Ischemia; Corpus Striatum; Male; Rats; Rats, Sprague-Dawley; Xanth | 1996 |
Effect of propentofylline on [3H]-leucine incorporation into protein of postischemic rat brain.
Topics: Animals; Anti-Ulcer Agents; Brain; Brain Ischemia; Leucine; Male; Protein Biosynthesis; Rats; Rats, | 1996 |
Propentofylline potentiates induced ischemic tolerance in gerbil hippocampal neurons via adenosine receptor.
Topics: Animals; Brain Ischemia; Gerbillinae; Hippocampus; Injections, Intraperitoneal; Ischemic Preconditio | 1998 |
Increased ATP production during long-term brain ischemia in rats in the presence of propentofylline.
Topics: Adenosine Triphosphate; Animals; Arterial Occlusive Diseases; Biomarkers; Brain Ischemia; Carotid Ar | 1998 |
Properties of activated microglia and pharmacologic interference by propentofylline.
Topics: Adult; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Brain Ischemia; | 1998 |
Effect of propentofylline on hippocampal brain energy state and amyloid precursor protein concentration in a rat model of cerebral hypoperfusion.
Topics: Amyloid beta-Protein Precursor; Animals; Brain Ischemia; Energy Metabolism; Hemodynamics; Hippocampu | 1998 |
Propentofylline attenuates microglial reaction in the rat spinal cord induced by middle cerebral artery occlusion.
Topics: Animals; Brain Ischemia; Cerebral Arterial Diseases; Male; Microglia; Neuroprotective Agents; Rats; | 1999 |
Effects of adenosine agonists and an antagonist on excitatory transmitter release from the ischemic rabbit hippocampus.
Topics: Adenosine; Animals; Brain Ischemia; Chromatography, High Pressure Liquid; Electroencephalography; Ex | 2000 |
Effect of propentofylline on cerebral blood flow in a gerbil focal cerebral ischemia.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Gerbillinae; Neuroprotective A | 2001 |
Microglial reaction in focal cerebral ischaemia induced by intra-carotid homologous clot injection.
Topics: Animals; Body Temperature; Brain; Brain Ischemia; Carotid Artery Thrombosis; Hemodynamics; Immunohis | 2001 |
Neuromodulatory effect of propentofylline on rat brain under acute and long-term hypoperfusion.
Topics: Adenosine; Animals; Blood Gas Analysis; Blood Pressure; Brain; Brain Ischemia; Carotid Arteries; Cyc | 2001 |
Disturbance of cerebral autoregulation after global ischemia and the stabilizing role of adenosine.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Homeostasis; Rats; Xan | 1992 |
[Effects of propentofylline (HWA285) on recovery of brain function following total cerebral ischemia (TCI) in dogs].
Topics: Animals; Brain; Brain Ischemia; Dogs; Xanthines | 1992 |
Effect of propentofylline (HWA 285) on extracellular purines and excitatory amino acids in CA1 of rat hippocampus during transient ischaemia.
Topics: Adenosine Deaminase; Amino Acids; Animals; Brain Ischemia; Dialysis; Electroencephalography; Hippoca | 1990 |
Protection against ischemic brain damage using propentofylline in gerbils.
Topics: Animals; Brain; Brain Ischemia; Gerbillinae; Male; Xanthines | 1988 |