propentofylline has been researched along with Acute Onset Vascular Dementia in 10 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase." | 8.82 | Propentofylline for dementia. ( Frampton, M; Harvey, RJ; Kirchner, V, 2003) |
| "Propentofylline is a novel therapeutic agent for dementia that readily crosses the blood-brain barrier and acts by blocking the uptake of adenosine and inhibiting the enzyme phosphodiesterase." | 4.82 | Propentofylline for dementia. ( Frampton, M; Harvey, RJ; Kirchner, V, 2003) |
| "Propentofylline was found to provide consistent improvements over placebo in efficacy assessments for both AD and VaD patients." | 2.40 | Propentofylline in the treatment of Alzheimer's disease and vascular dementia: a review of phase III trials. ( Erkinjuntti, T; Karlsson, I; Kittner, B; Marcusson, J; Roessner, M; Rother, M, 1998) |
| "In experimental models of vascular dementia and/or Alzheimer's disease it improves cognitive functions, inhibits inflammatory processes as well as excessive activation of microglia, formation of free radicals, cytocines and abnormal amyloid precursor proteins (APP)." | 2.40 | [New pharmacologic aspects in the neurologic profile of propentofylline (Karsivan ad us. vet.)]. ( Kapl, D; Rudolphi, KA, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Frampton, M | 1 |
| Harvey, RJ | 1 |
| Kirchner, V | 1 |
| Rother, M | 4 |
| Kittner, B | 6 |
| Rudolphi, K | 1 |
| Rössner, M | 2 |
| Labs, KH | 1 |
| Mielke, R | 2 |
| Ghaemi, M | 1 |
| Kessler, J | 1 |
| Szelies, B | 1 |
| Herholz, K | 1 |
| Heiss, WD | 1 |
| Erkinjuntti, T | 3 |
| Roessner, M | 1 |
| Marcusson, J | 1 |
| Karlsson, I | 1 |
| Möller, HJ | 1 |
| Rosenkranz, B | 1 |
| Kapl, D | 1 |
| Rudolphi, KA | 1 |
| De Deyn, PP | 1 |
| Ringheim, GE | 1 |
7 reviews available for propentofylline and Acute Onset Vascular Dementia
| Article | Year |
|---|---|
Propentofylline for dementia.
Topics: Aged; Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Neuroprotective Agents; Pick Disease | 2003 |
HWA 285 (propentofylline)--a new compound for the treatment of both vascular dementia and dementia of the Alzheimer type.
Topics: Activities of Daily Living; Alzheimer Disease; Brain Ischemia; Clinical Trials as Topic; Dementia, V | 1996 |
Clinical trials in dementia with propentofylline.
Topics: Adenosine; Aged; Alzheimer Disease; Clinical Trials, Phase III as Topic; Dementia, Vascular; Double- | 1997 |
Propentofylline in the treatment of Alzheimer's disease and vascular dementia: a review of phase III trials.
Topics: Alzheimer Disease; Clinical Trials, Phase III as Topic; Dementia, Vascular; Humans; Neuroprotective | 1998 |
Propentofylline in the treatment of vascular dementia and Alzheimer-type dementia: overview of phase I and phase II clinical trials.
Topics: Aged; Alzheimer Disease; Brain; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topi | 1998 |
[New pharmacologic aspects in the neurologic profile of propentofylline (Karsivan ad us. vet.)].
Topics: Adenosine; Alzheimer Disease; Animals; Cerebrovascular Circulation; Cognition Disorders; Dementia, V | 1998 |
Glial modulating and neurotrophic properties of propentofylline and its application to Alzheimer's disease and vascular dementia.
Topics: Alzheimer Disease; Animals; Dementia, Vascular; Humans; Learning; Memory; Neuroglia; Neuroprotective | 2000 |
2 trials available for propentofylline and Acute Onset Vascular Dementia
| Article | Year |
|---|---|
Propentofylline improves regional cerebral glucose metabolism and neuropsychologic performance in vascular dementia.
Topics: Aged; Anti-Ulcer Agents; Cerebral Cortex; Dementia, Vascular; Disease Progression; Female; Glucose; | 1996 |
Investigating the natural course and treatment of vascular dementia and Alzheimer's disease. Parallel study populations in two randomized, placebo-controlled trials.
Topics: Aged; Alzheimer Disease; Cognition; Dementia, Vascular; Disease Progression; Female; Humans; Male; N | 2000 |
1 other study available for propentofylline and Acute Onset Vascular Dementia
| Article | Year |
|---|---|
[Dementia-related diseases. Propentofyllin--a neuroprotective glia cell modulator].
Topics: Alzheimer Disease; Dementia; Dementia, Vascular; Humans; Neuroglia; Xanthines | 1998 |