propantheline has been researched along with Muscle Contraction in 23 studies
Propantheline: A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oxybutynin has statistically significant effects on subjective symptoms and objective urodynamic parameters in patients with detrusor hyperactivity compared to propantheline." | 2.67 | Randomized, double-blind, multicenter trial on treatment of frequency, urgency and incontinence related to detrusor hyperactivity: oxybutynin versus propantheline versus placebo. ( Bunke, B; de Geeter, P; Ebner, A; Faber, P; Hannappel, J; Heidler, H; Madersbacher, H; Melchior, H; Schäfer, W; Thüroff, JW, 1991) |
| "Propiverine is a drug for the treatment of incontinence and pollakiuria." | 1.30 | [Effects of propiverine hydrochloride (propiverine) on isolated rat and dog urinary bladder]. ( Kaneko, S; Nakano, D; Nishimori, T; Ohara, M, 1999) |
| "Pirenzepine is an antisecretory anticholinergic type drug that has recently been shown to be relatively free of usual anticholinergic side effects on esophageal smooth muscle." | 1.27 | Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol. ( Castell, DO; Castell, JA; Dalton, CB; Hassan, M, 1986) |
| "Dicyclomine failed to cause inhibition of the barium chloride-induced contractions in the guinea pig vesicourethral smooth muscle." | 1.26 | In vitro study of antispasmodic effects of dicyclomine hydrochloride on vesicourethral smooth muscle of guinea pig and rabbit. ( Barbieri, EJ; DiGregorio, GJ; Khanna, OP; McMichael, R; Ruch, E, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (86.96) | 18.7374 |
| 1990's | 2 (8.70) | 18.2507 |
| 2000's | 1 (4.35) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mokry, J | 1 |
| Nosalova, G | 1 |
| Jakubesova, M | 1 |
| Blaivas, JG | 1 |
| Barbalias, GA | 1 |
| Hongo, M | 1 |
| Traube, M | 1 |
| McCallum, RW | 1 |
| Karol, JB | 1 |
| Anderson, RU | 1 |
| Kaneko, S | 1 |
| Nakano, D | 1 |
| Ohara, M | 1 |
| Nishimori, T | 1 |
| Finkbeiner, AE | 1 |
| Bissada, NK | 1 |
| Welch, LT | 1 |
| Khanna, OP | 1 |
| DiGregorio, GJ | 1 |
| Barbieri, EJ | 1 |
| McMichael, R | 1 |
| Ruch, E | 1 |
| Low, JA | 1 |
| Thompson, IM | 1 |
| Lauvetz, R | 1 |
| Benson, GS | 1 |
| Sarshik, SA | 1 |
| Raezer, DM | 1 |
| Wein, AJ | 2 |
| Horioka, M | 1 |
| Aoyama, T | 1 |
| Karasawa, H | 1 |
| Honig, CR | 1 |
| Frierson, JL | 1 |
| Thüroff, JW | 1 |
| Bunke, B | 1 |
| Ebner, A | 1 |
| Faber, P | 1 |
| de Geeter, P | 1 |
| Hannappel, J | 1 |
| Heidler, H | 1 |
| Madersbacher, H | 1 |
| Melchior, H | 1 |
| Schäfer, W | 1 |
| Hassan, M | 1 |
| Dalton, CB | 1 |
| Castell, JA | 1 |
| Castell, DO | 1 |
| Rose, JG | 1 |
| Gillenwater, JY | 1 |
| Nagendra, NK | 1 |
| Goldfarb, M | 1 |
| Yu, RC | 1 |
| Jacoby, HI | 1 |
| Marshall, CH | 1 |
| Gregory, JG | 1 |
| Schoenberg, HW | 1 |
| Story, ME | 1 |
| Bentley, GA | 1 |
| Pedersen, E | 2 |
| Bjarnason, EV | 2 |
| Hansen, PH | 2 |
| Diokno, AC | 1 |
| Hyndman, CW | 1 |
| Hardy, DA | 1 |
| Lapides, J | 1 |
| Kumada, S | 1 |
| Otsuka, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Placebo-Controlled Study to Assess the Efficacy of Propantheline for the Treatment of Overactive Bladder[NCT01640002] | Phase 1 | 42 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for propantheline and Muscle Contraction
| Article | Year |
|---|---|
Uropharmacology: part VI. Parasympathetic depressants.
Topics: Acetylcholine; Atropine; Belladonna Alkaloids; Benactyzine; Cyclohexanes; Hemicholinium 3; Humans; M | 1977 |
4 trials available for propantheline and Muscle Contraction
| Article | Year |
|---|---|
Comparison of effects of nifedipine, propantheline bromide, and the combination on esophageal motor function in normal volunteers.
Topics: Administration, Oral; Adult; Capsules; Esophagogastric Junction; Esophagus; Humans; Male; Manometry; | 1984 |
Oxybutynin in bladder spasm, neurogenic bladder, and enuresis.
Topics: Adult; Amines; Bethanechol Compounds; Child; Clinical Trials as Topic; Dicyclomine; Enuresis; Humans | 1976 |
Randomized, double-blind, multicenter trial on treatment of frequency, urgency and incontinence related to detrusor hyperactivity: oxybutynin versus propantheline versus placebo.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Humans; Male; Mandelic Acid | 1991 |
[Neurogenic disturbances of the bladder treated with flavoxate (Urispadol)].
Topics: Clinical Trials as Topic; Depression, Chemical; Flavonoids; Humans; Muscle Contraction; Muscle, Smoo | 1973 |
18 other studies available for propantheline and Muscle Contraction
| Article | Year |
|---|---|
Propantheline and in vitro reactivity of urinary bladder smooth muscle in guinea pigs.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniques; Mandelic | 2005 |
Detrusor-external sphincter dyssynergia in men with multiple sclerosis: an ominous urologic condition.
Topics: Adult; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Contraction; Muscle, Smooth; Pr | 1984 |
Neuropharmacologic evaluation in spinal cord injury patients using membrane catheter cystosphincterometry.
Topics: Bethanechol Compounds; Catheterization; Drug Evaluation; Humans; Male; Muscle Contraction; Phentolam | 1980 |
[Effects of propiverine hydrochloride (propiverine) on isolated rat and dog urinary bladder].
Topics: Acetylcholine; Animals; Atropine; Benzilates; Butylamines; Dogs; Dose-Response Relationship, Drug; E | 1999 |
In vitro study of antispasmodic effects of dicyclomine hydrochloride on vesicourethral smooth muscle of guinea pig and rabbit.
Topics: Acetylcholine; Animals; Atropine; Barium; Chlorides; Cyclohexanecarboxylic Acids; Dicyclomine; Dose- | 1979 |
Urethral behavior during the involuntary detrusor contraction.
Topics: Humans; Male; Muscle Contraction; Parasympathetic Nervous System; Phenoxybenzamine; Phentolamine; Pr | 1977 |
Bladder muscle contractility. Comparative effects and mechanisms of action of atropine, propantheline, flavoxate, and imipramine.
Topics: Animals; Atropine; Barium; Bethanechol Compounds; Chlorides; Dogs; Female; Flavonoids; Flavoxate; Im | 1977 |
Pharmacological activity of propantheline bromide mixed with antacids in guinea-pigs and human.
Topics: Aluminum Hydroxide; Animals; Drug Combinations; Female; Guinea Pigs; Humans; In Vitro Techniques; Ma | 1977 |
Neurons intrinsic to arterioles initiate postcontraction vasodilation.
Topics: Animals; Arteries; Atropine; Blood Pressure; Denervation; Dipyridamole; Dogs; Gallamine Triethiodide | 1976 |
Pirenzepine and propantheline effects on esophageal pressure responses to bethanechol.
Topics: Adult; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Esophagus; Female; Gastrointestinal Ag | 1986 |
The effect of adrenergic and cholinergic agents and their blockers upon ureteral activity.
Topics: Adrenergic alpha-Agonists; Animals; Bethanechol Compounds; Dogs; Epinephrine; Female; Isoproterenol; | 1974 |
Vesical distension and ureteral activity in the canine.
Topics: Anesthesia, Local; Animals; Denervation; Dogs; Female; Lidocaine; Male; Muscle Contraction; Pressure | 1974 |
Gastric motor-stimulating activity of gastrin tetrapeptide in dogs.
Topics: Animals; Atropine; Blood Pressure; Carbachol; Chlorpromazine; Colon; Dogs; Duodenum; Gastrins; Gastr | 1969 |
A comparison of the action of Tofranil and Pro-Banthine on the urinary bladder.
Topics: Animals; Depression, Chemical; Dogs; Electric Stimulation; Female; Imipramine; Muscle Contraction; P | 1974 |
The effects of drugs and treatments upon adrenaline re-reversal in the rabbit.
Topics: Animals; Blood Pressure; Bretylium Compounds; Cocaine; Diphenhydramine; Ear; Epinephrine; Female; Gu | 1974 |
The effect of Flavoxate R on neurogenic bladder dysfunction.
Topics: Depression, Chemical; Flavonoids; Humans; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pr | 1972 |
Comparison of action of imipramine (tofranil) and propantheline (probanthine) on detrusor contraction.
Topics: Enuresis; Humans; Imipramine; Muscle Contraction; Muscle, Smooth; Propantheline; Urinary Bladder; Ur | 1972 |
[Inhibitory activities of several atropine-like drugs on the contraction of the digestive system and urinary bladder induced by the parasympathetic nerve stimulation in the dog].
Topics: Animals; Atropine; Benactyzine; Colon; Depression, Chemical; Digestive System; Dogs; Electric Stimul | 1970 |