propantheline has been researched along with Multiple Sclerosis in 5 studies
Propantheline: A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blaivas, JG | 2 |
| Barbalias, GA | 1 |
| Rabey, JM | 1 |
| Moriel, EZ | 1 |
| Farkas, A | 1 |
| Firstater, M | 1 |
| Vardi, I | 1 |
| Streifler, M | 1 |
| Gajewski, JB | 1 |
| Awad, SA | 1 |
| DeLisa, JA | 1 |
| Miller, RM | 1 |
| Mikulic, MA | 1 |
| Hammond, MC | 1 |
1 trial available for propantheline and Multiple Sclerosis
| Article | Year |
|---|---|
Oxybutynin versus propantheline in patients with multiple sclerosis and detrusor hyperreflexia.
Topics: Female; Humans; Male; Mandelic Acids; Multiple Sclerosis; Parasympatholytics; Propantheline; Prospec | 1986 |
4 other studies available for propantheline and Multiple Sclerosis
| Article | Year |
|---|---|
Detrusor-external sphincter dyssynergia in men with multiple sclerosis: an ominous urologic condition.
Topics: Adult; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Muscle Contraction; Muscle, Smooth; Pr | 1984 |
Management of bladder dysfunction in multiple sclerosis.
Topics: Adult; Aged; Bethanechol Compounds; Female; Humans; Male; Middle Aged; Multiple Sclerosis; Propanthe | 1980 |
Detrusor hyperreflexia in multiple sclerosis. Alleviation by a combination of imipramine and propantheline, a clinico-laboratory study.
Topics: Adult; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Imipramine; Male; Middle Aged; Mu | 1979 |
Multiple sclerosis: Part II. Common functional problems and rehabilitation.
Topics: Cognition Disorders; Constipation; Deglutition Disorders; Humans; Multiple Sclerosis; Propantheline; | 1985 |