Page last updated: 2024-11-03

propantheline and Gastric Ulcer

propantheline has been researched along with Gastric Ulcer in 21 studies

Propantheline: A muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.

Research Excerpts

ExcerptRelevanceReference
"Fifty-eight adult outpatients with endoscopically verified gastric, prepyloric or duodenal ulcers completed a double-blind trial of treatment with either cimetidine, 1 g daily, plus propantheline, 45 mg daily (group A) or cimetidine, 1 g daily, plus placebo (group B)."9.05Treatment of gastroduodenal ulcers with cimetidine in combination with low-dose propantheline. ( Hendel, L; Mosbech, J; Paerregaard, A; Schultz-Larsen, K; Tobiasen, K, 1983)
"Seventy-one patients with duodenal ulcer disease completed a 3- to 6-week controlled randomized trial in which cimetidine (1 g daily) was compared with an optimally effective dose of propantheline."9.05Cimetidine or propantheline combined with antacid therapy for short-term treatment of duodenal ulcer. ( Adami, HO; Björklund, O; Enander, LK; Gustavsson, S; Lööf, L; Nordahl, A; Rosén, A, 1982)
"Fifty-eight adult outpatients with endoscopically verified gastric, prepyloric or duodenal ulcers completed a double-blind trial of treatment with either cimetidine, 1 g daily, plus propantheline, 45 mg daily (group A) or cimetidine, 1 g daily, plus placebo (group B)."5.05Treatment of gastroduodenal ulcers with cimetidine in combination with low-dose propantheline. ( Hendel, L; Mosbech, J; Paerregaard, A; Schultz-Larsen, K; Tobiasen, K, 1983)
"Seventy-one patients with duodenal ulcer disease completed a 3- to 6-week controlled randomized trial in which cimetidine (1 g daily) was compared with an optimally effective dose of propantheline."5.05Cimetidine or propantheline combined with antacid therapy for short-term treatment of duodenal ulcer. ( Adami, HO; Björklund, O; Enander, LK; Gustavsson, S; Lööf, L; Nordahl, A; Rosén, A, 1982)
"Gastric ulcerations were produced in rats by oral administration of aspirin (ASA) suspended in a vehicle consisting of either water or increasing concentrations of HCl (0."3.67Distinction between antiulcer effect and cytoprotection. ( Davis, JP; Field, SO; Lancaster, C; Nezamis, JE; Robert, A, 1984)
" Intragastric administration of PB, CM or TP produced dose-dependent inhibition of gastric ulceration with parallel dose-response curves."1.26Synergistic actions of propantheline bromide with cimetidine and thiopropazate hydrochloride in the prevention of stress ulcer formation in rats. ( Bianchi, RG; Calhoun, DW; Dajani, EZ, 1979)
"A gastroduodenal combination preparation was introduced at a deliberately high dosage into a clinical treatment schema."1.26[Clinical treatment of inflammatory and benign ulcerous diseases of the stomach and duodenum with a new combination preparation (Aci-Tensilan) (author's transl)]. ( van de Loo, W, 1976)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199021 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KOWALEWSKI, K2
MACKENZIE, WC1
SHNITKA, TK1
BAIN, GO1
SPARACIA, A1
Konturek, SJ1
Radecki, T1
Brzozowski, T1
Piastucki, I1
Dembińska-Kieć, A1
Zmuda, A1
Gustavsson, S2
Adami, HO2
Björklund, O2
Enander, LK2
Lundqvist, G1
Lööf, L2
Nordahl, A2
Paerregaard, A1
Hendel, L1
Schultz-Larsen, K1
Tobiasen, K1
Mosbech, J1
Robert, A1
Lancaster, C1
Davis, JP1
Field, SO1
Nezamis, JE1
Isenberg, JI1
Rosén, A1
Marini, U1
Visconti, GP1
Spotti, D1
Geniram, A1
Reikowski, H1
Dairman, WM1
Juhasz, L1
Guth, PH1
Aures, D1
Paulsen, G1
Dajani, EZ1
Bianchi, RG1
Calhoun, DW1
van de Loo, W1
Wang, JC1
Ito, M1
Fujii, A1
Suzuki, Y1
Southgate, PJ1
Ottenjann, R1
Winston, MA1
Guth, P1
Endow, JS1
Blahd, WH1
Lee, YH1
Mollison, KW1
Cheng, WD1

Trials

4 trials available for propantheline and Gastric Ulcer

ArticleYear
Fasting blood levels of gastrin, somatostatin, and pancreatic polypeptide in peptic ulcer disease.
    Scandinavian journal of gastroenterology, 1982, Volume: 17, Issue:1

    Topics: Adult; Aged; Cimetidine; Duodenal Ulcer; Fasting; Female; Gastrins; Humans; Male; Middle Aged; Pancr

1982
Treatment of gastroduodenal ulcers with cimetidine in combination with low-dose propantheline.
    Acta medica Scandinavica, 1983, Volume: 213, Issue:3

    Topics: Adolescent; Adult; Aged; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Co

1983
Are anticholinergics plus antacids truly as effective as cimetidine plus antacids in the treatment of duodenal ulcer? Comments on a clinical trial.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:5

    Topics: Antacids; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination; Duodenal Ulcer; Guanidine

1982
Cimetidine or propantheline combined with antacid therapy for short-term treatment of duodenal ulcer.
    Digestive diseases and sciences, 1982, Volume: 27, Issue:5

    Topics: Adult; Aged; Antacids; Cimetidine; Clinical Trials as Topic; Drug Therapy, Combination; Duodenal Ulc

1982

Other Studies

17 other studies available for propantheline and Gastric Ulcer

ArticleYear
Protective action of pro-banthine (SC-3171) on experimental gastric ulcers of rats.
    Canadian Medical Association journal, 1954, Volume: 71, Issue:5

    Topics: Animals; Parasympatholytics; Peptic Ulcer; Propantheline; Rats; Stomach Ulcer

1954
[Effect of propantheline bromide on experimental gastric ulcer induced by pyloric ligation].
    Rivista di patologia e clinica, 1957, Volume: 12, Issue:12

    Topics: Ligation; Methantheline; Peptic Ulcer; Propantheline; Pylorus; Quaternary Ammonium Compounds; Stomac

1957
Gastric cytoprotection by prostaglandins, ranitidine, and probanthine in rats. Role of endogenous prostaglandins.
    Scandinavian journal of gastroenterology, 1981, Volume: 16, Issue:1

    Topics: Animals; Aspirin; Epoprostenol; Furans; Gastric Juice; Gastric Mucosa; Histamine H2 Antagonists; Hyd

1981
Distinction between antiulcer effect and cytoprotection.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 101

    Topics: 16,16-Dimethylprostaglandin E2; Animals; Anti-Ulcer Agents; Aspirin; Cimetidine; Ethanol; Female; Ga

1984
[Trithiozine versus propantheline in the therapy of gastric ulcer: double-blind clinical studies].
    La Clinica terapeutica, 1980, Feb-29, Volume: 92, Issue:4

    Topics: Adult; Aged; Anti-Ulcer Agents; Double-Blind Method; Female; Humans; Male; Middle Aged; Morpholines;

1980
[Experimental testing of a new gastrotherapeutic agent].
    Fortschritte der Medizin, 1976, Jan-22, Volume: 94, Issue:3

    Topics: Adult; Antacids; Antipsychotic Agents; Drug Combinations; Drug Evaluation; Female; Gastric Mucosa; G

1976
A study in mice of benzodiazephine-anticholinergic interaction: protection against restraint-immersion and forced exertion-induced gastric mucosal erosion.
    Pharmacology, 1978, Volume: 17, Issue:2

    Topics: Animals; Anti-Anxiety Agents; Chlordiazepoxide; Diazepam; Dose-Response Relationship, Drug; Drug Eva

1978
Topical aspirin plus HCl gastric lesions in the rat. Cytoprotective effect of prostaglandin, cimetidine, and probanthine.
    Gastroenterology, 1979, Volume: 76, Issue:1

    Topics: Animals; Aspirin; Cimetidine; Depression, Chemical; Gastric Juice; Guanidines; Hydrochloric Acid; In

1979
Synergistic actions of propantheline bromide with cimetidine and thiopropazate hydrochloride in the prevention of stress ulcer formation in rats.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:3

    Topics: Animals; Cimetidine; Dose-Response Relationship, Drug; Drug Synergism; Guanidines; Humans; Male; Phe

1979
[Clinical treatment of inflammatory and benign ulcerous diseases of the stomach and duodenum with a new combination preparation (Aci-Tensilan) (author's transl)].
    MMW, Munchener medizinische Wochenschrift, 1976, Feb-27, Volume: 118, Issue:9

    Topics: Adolescent; Adult; Aged; Aluminum Hydroxide; Antacids; Calcium Carbonate; Carbenoxolone; Carbonates;

1976
[Effect of Chinese herbal medicine, western medicine and Chinese and western medicine combined in the treatment of peptic ulcer].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1985, Volume: 5, Issue:1

    Topics: Adolescent; Adult; Aged; Duodenal Ulcer; Female; Humans; Male; Medicine, Chinese Traditional; Medici

1985
Healing-promoting action of dried aluminium hydroxide gel evaluated by the method of histological measurements in acetic acid ulcer of rats.
    Japanese journal of pharmacology, 1985, Volume: 37, Issue:4

    Topics: Acetates; Acetic Acid; Aluminum Hydroxide; Animals; Male; Propantheline; Rats; Rats, Inbred Strains;

1985
Central and peripheral actions of the acetylcholine antagonist, ambutonium bromide.
    Archives internationales de pharmacodynamie et de therapie, 1972, Volume: 196, Issue:2

    Topics: Acetylcholine; Animals; Atropine; Drug Antagonism; Guinea Pigs; Histamine H1 Antagonists; Ileum; In

1972
Gastric secretion and peptic ulcer in rats with experimentally-induced polycythemia.
    Digestion, 1972, Volume: 7, Issue:3

    Topics: Animals; Blood Transfusion; Depression, Chemical; Erythrocytes; Gastric Acidity Determination; Gastr

1972
[Conservative therapy of gastroduodenal ulcer].
    Minerva medica, 1973, Dec-26, Volume: 64, Issue:93

    Topics: Antacids; Duodenal Ulcer; Glycopyrrolate; Glycyrrhiza; Humans; Parasympatholytics; Peptic Ulcer; Pla

1973
Enhancement of pancreatic concentration of 75Se-selenomethionine.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1974, Volume: 15, Issue:8

    Topics: Animals; Bethanechol Compounds; Cholecystokinin; Female; Glucagon; Humans; Pancreatic Cyst; Pancreat

1974
The effects of anti-ulcer agents on indomethacin-induced gastric ulceration in the rat.
    Archives internationales de pharmacodynamie et de therapie, 1971, Volume: 192, Issue:2

    Topics: Analysis of Variance; Animals; Antacids; Drug Antagonism; Gastric Juice; Gastric Mucosa; Indomethaci

1971