Page last updated: 2024-11-03

propafenone and Recrudescence

propafenone has been researched along with Recrudescence in 70 studies

Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone and propafenone are commonly used to maintain sinus rhythm in patients with atrial fibrillation (AF)."9.34Comparison of Amiodarone and Propafenone in Blanking Period after Radiofrequency Catheter Ablation in Patients with Atrial Fibrillation: A Propensity Score-Matched Study. ( Chen, L; Chen, X; Fan, L; Gong, K; Huang, R; Lin, J; Xu, Z; Zhang, F; Zhang, Y, 2020)
"Our objective was to compare the efficacy of dronedarone and propafenone in maintaining sinus rhythm in patients with atrial fibrillation (AF) after electrical cardioversion."9.19Efficacy of dronedarone versus propafenone in the maintenance of sinus rhythm in patients with atrial fibrillation after electrical cardioversion. ( Byeon, K; Chun, KJ; Im, SI; Kim, JS; On, YK; Park, KM; Park, SJ, 2014)
"A prospective, randomized study was conducted to evaluate the efficacy and tolerability of oral propafenone and quinidine for the conversion of paroxysmal atrial fibrillation (AF)."9.14Efficacy and tolerability of oral propafenone versus quinidine in the treatment of recent onset atrial fibrillation: A randomized, prospective study. ( Kochanowski, J; Kosior, DA; Opolski, G; Piatkowski, R; Postuła, M; Rabczenko, D; Scisło, P, 2009)
"This prospective, randomized, single-blinded, placebo-controlled study compared the efficacy and safety of sotalol and propafenone when used for long-term prevention of atrial fibrillation."9.11Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation. ( Chlouverakis, GI; Hamilos, ME; Igoumenidis, NE; Klapsinos, NC; Kochiadakis, GE; Tzerakis, PG; Vardas, PE, 2004)
"We report a double-blind, multicenter, multinational, placebo-controlled, and well-controlled trial to prove that the sustained-release (SR) formulation of propafenone is superior to placebo in preventing symptoms of paroxysmal atrial fibrillation (AF)."9.10Efficacy and safety of propafenone sustained release in the prophylaxis of symptomatic paroxysmal atrial fibrillation (The European Rythmol/Rytmonorm Atrial Fibrillation Trial [ERAFT] Study). ( Camez, A; Eberle, S; Hewkin, A; Kalsch, B; Lip, GY; Lombardi, F; Meinertz, T; Sadowski, ZP, 2002)
"The objective of this randomized, double-blind, placebo-controlled clinical trial was to test the efficacy and safety of a new sustained-release preparation of the antiarrhythmic drug propafenone (propafenone SR) in reducing the frequency of symptomatic arrhythmia recurrences in patients with atrial fibrillation (AF)."9.10Efficacy and safety of sustained-release propafenone (propafenone SR) for patients with atrial fibrillation. ( Carlson, M; Fava, G; Page, RL; Pritchett, EL; Undesser, K, 2003)
"Amiodarone and propafenone were superior to sotalol in maintaining long-term normal sinus rhythm in patients with atrial fibrillation."9.09Amiodarone, sotalol, or propafenone in atrial fibrillation: which is preferred to maintain normal sinus rhythm? ( Chrysostomakis, SI; Igoumenidis, NE; Kaleboubas, MD; Kochiadakis, GE; Marketou, ME; Mavrakis, HE; Vardas, PE, 2000)
"This study was performed to evaluate, using a randomized double-blind, placebo-controlled protocol, the long-term efficacy and safety of propafenone and sotalol in maintaining sinus rhythm after conversion of recurrent symptomatic atrial fibrillation (AF)."9.09Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation. ( Bellandi, F; Dabizzi, RP; Frascarelli, F; Giovannini, T; Leoncini, M; Maioli, M; Simonetti, I, 2001)
"To evaluate, in a prospective and randomized fashion, the efficacy of a pretreatment with verapamil (V) in reducing recurrences of atrial fibrillation (AF) after electrical cardioversion (C)."9.09Pretreatment with verapamil in patients with persistent or chronic atrial fibrillation who underwent electrical cardioversion. ( De Matteis, C; De Simone, A; Di Napoli, T; Di Stasio, M; Gasparini, M; Petrazzuoli, F; Rotunno, R; Stabile, G; Turco, P; Vitale, DF, 1999)
"Propafenone, given before electrical cardioversion for chronic atrial fibrillation does not affect the mean defibrillation threshold or the rate of successful arrhythmia conversion."9.08Effects of oral propafenone administration before electrical cardioversion of chronic atrial fibrillation: a placebo-controlled study. ( Bianconi, L; Castro, A; Chieffi, M; Lukic, V; Mennuni, M; Santini, M, 1996)
"The study consisted of a 3-month treatment with oral propafenone hydrochloride or quinidine sulphate in patients with paroxysmal symptomatic atrial fibrillation, according to a double-blind randomized system."9.08Comparisons of oral propafenone and quinidine as an initial treatment option in patients with symptomatic paroxysmal atrial fibrillation: a double-blind, randomized trial. ( Chang, MS; Chen, SA; Chiang, CE; Lee, SH; Tai, CT; Wang, SP; Wen, ZC, 1996)
"This multicentre, randomized, double-blind study, conducted in parallel groups, was designed to compare the efficacy and safety of cibenzoline (C) and oral propafenone (P) in the prevention of recurrent atrial arrhythmias (M) over a 6-month period."9.08[Cibenzoline versus propafenone by the oral route for preventing recurrence of atrial arrhythmia: multicenter, randomized, double-blind study]. ( Bleinc, D; Canler, A; Lardoux, H; Maison Blanche, P; Marchand, X; Péraudeau, P; Rouesnel, P; Scheck, F, 1996)
"To evaluate the efficacy of propafenone for suppression of recurrent paroxysmal symptomatic atrial fibrillation (AF), patients with frequent episodes of AF entered an open-label, dose-ranging study to determine the maximal tolerated dose of propafenone and were subsequently randomized to alternate between propafenone and placebo every month for 4 months."9.06Usefulness of propafenone for recurrent paroxysmal atrial fibrillation. ( Connolly, SJ; Hoffert, DL, 1989)
"Sixteen patients with ventricular tachycardia (VT) or nonfatal cardiac arrest were treated with propafenone (P), 900 mg/day."9.05Clinical efficacy and electrophysiology of oral propafenone for ventricular tachycardia. ( Connolly, SJ; Echt, DS; Kates, RE; Lebsack, CS; Mason, JW; Winkle, RA, 1983)
"The clinical outcomes of 114 patients with atrial fibrillation who had been treated with the innovator propafenone, and in whom the drug was then replaced with generic propafenone because of cost containment, were compared."7.72Efficacy of substituting innovator propafenone for its generic formulation in patients with atrial fibrillation. ( Amit, G; Bonneh, DY; Grosbard, A; Ilia, R; Katz, A; Liss, T; Rosen, A; Wagshal, AB, 2004)
"The antiarrhythmic effect of oral propafenone was evaluated in 10 patients with Wolff-Parkinson-White syndrome presenting with non-ventricular arrhythmias (paroxysmal supraventricular tachycardia n = 7, atrial fibrillation or flutter n = 3)."7.68Propafenone in the prevention of non-ventricular arrhythmias associated with the Wolff-Parkinson-White syndrome. ( Kallikazaros, I; Papoutsakis, P; Stefanadis, C; Vassiliadis, I, 1990)
"To determine the electrophysiological properties of oral propafenone, 50 patients (39 male and 11 female, aged 31 to 80 years) with sustained ventricular tachycardia or ventricular fibrillation underwent serial electrophysiological drug testing, using propafenone (750 to 900 mg daily) as the anti-arrhythmic regimen of first choice."7.68Acute and long-term efficacy of propafenone in patients with sustained ventricular tachyarrhythmias: assessment with programmed ventricular stimulation. ( Frohner, K; Hief, C; Podczeck, A; Steinbach, KK; Stix, G, 1991)
"Propafenone may be effective in some patients for long term prevention of atrial fibrillation, although efficacy may decrease over time."7.68Long term efficacy of propafenone for prevention of atrial fibrillation. ( Kerr, CR; Kyles, AE; Murdock, CJ; Vorderbrugge, S; Yeung-Lai-Wah, JA, 1991)
"One hundred and fourteen patients were included in an open multicenter trial of the prevention of atrial arrhythmias by propafenone and of the tolerability of this anti-arrhythmic agent after a year."7.68[Efficacy and tolerance of propafenone in the prevention after a year of recurrent atrial arrhythmia. Results of a multicenter study of 114 patients]. ( Maarek-Charbit, M; Motté, G; Sirinelli, A, 1992)
"One hundred and ninety-six patients with stable atrial fibrillation of recent onset received propafenone (98 patients) or Amiodarone (98 patients) intravenously."7.68[The efficacy of intravenous propafenone and amiodarone in the conversion of recent-onset atrial fibrillation. A 1-year follow-up with oral treatment]. ( Bellandi, F; Cantini, F; Dabizzi, RP; Palchetti, R; Pedone, T, 1993)
"Electrophysiologic and hemodynamic studies were performed before and after intravenous infusion of a new antiarrhythmic agent, propafenone, in 28 patients with recurrent ventricular tachycardia."7.67Electrophysiologic and hemodynamic effects of intravenous propafenone in patients with recurrent ventricular tachycardia. ( DiCarlo, L; Morady, F; Scheinman, MM; Schwartz, AB; Shapiro, W; Shen, EN; Sung, RJ, 1984)
"The purpose of our study was to assess the efficacy of Propafenon in comparison with Disopyramide in the long-term treatment of repetitive ventricular tachycardia."7.67[Comparative study on the efficacy of disopyramide and propafenone in the prevention of the recurrence of ventricular tachycardia]. ( Bomba, E; Bracchetti, D; Capucci, A; Lombardi, G; Naccarella, F; Palmieri, M, 1984)
"The efficacy of Propafenone to prevent exercise-induced ventricular arrhythmias (EIVA) has been studied in eleven patients affected by ischemic heart disease."7.67[Effects of propafenone on arrhythmias induced by exertion in patients with ischemic cardiopathy]. ( Arrigo, F; Giannetto, M; Luzza, F; Oreto, G; Patané, S; Virga, T, 1987)
"Propafenone was administered to 29 patients who had multiple episodes of recurrent ventricular tachycardia (VT) or ventricular fibrillation (VF) despite previous antiarrhythmic therapy."7.67Propafenone treatment of recurrent ventricular tachycardia: comparison of continuous electrocardiographic recording and electrophysiologic study in predicting drug efficacy. ( Heger, JJ; Hubbard, J; Miles, WM; Prystowsky, EN; Zipes, DP, 1984)
"Sixty patients who had recurrent episodes of symptomatic atrial fibrillation or flutter, or both, and who had failed one to five prior drug trials were treated with open label oral propafenone hydrochloride."7.67Long-term oral propafenone therapy for suppression of refractory symptomatic atrial fibrillation and atrial flutter. ( Antman, EM; Beamer, AD; Cantillon, C; Friedman, PL; Goldman, L; McGowan, N, 1988)
"The frequent recurrence of paroxysmal atrial fibrillation (PAF) despite the use of standard antiarrhythmic agents prompted the use of new therapeutic approaches."6.69Control of paroxysmal atrial fibrillation recurrence using combined administration of propafenone and quinidine. ( Chow, MS; Fan, C; Lau, CP; Tang, MO; Tse, HF, 2000)
"Amiodarone and propafenone are commonly used to maintain sinus rhythm in patients with atrial fibrillation (AF)."5.34Comparison of Amiodarone and Propafenone in Blanking Period after Radiofrequency Catheter Ablation in Patients with Atrial Fibrillation: A Propensity Score-Matched Study. ( Chen, L; Chen, X; Fan, L; Gong, K; Huang, R; Lin, J; Xu, Z; Zhang, F; Zhang, Y, 2020)
"Propafenone was prescribed at the initial dose of 600 mg/day in 65% of patients."5.31[Efficacy and tolerance of propafenone after correction of atrial fibrillation: PEPS pharmaco-epidemiologic study]. ( Davy, JM; Funck-Brentano, C; Jaillon, P; Mary-Krause, M; Simon, T; Weingrod, M, 2002)
"In our patient, recurrences of ventricular fibrillation were not prevented either by lidocaine, or amiodarone."5.29Sixty-six episodes of ventricular fibrillation within four hours: electrical stability restored by propafenone. ( Bellone, P; Spirito, P; Vecchio, C, 1994)
"Three patients experienced recurrence of AF in the early follow-up."5.29Role of transesophageal pacing in recurrent atrial fibrillation. Experience with propafenone. ( Bellizzi, G; Candelmo, F; Foffa, A; Guarino, P; Martino, DF; Morella, A; Parente, A; Turco, P; Viola, V, 1994)
"Our objective was to compare the efficacy of dronedarone and propafenone in maintaining sinus rhythm in patients with atrial fibrillation (AF) after electrical cardioversion."5.19Efficacy of dronedarone versus propafenone in the maintenance of sinus rhythm in patients with atrial fibrillation after electrical cardioversion. ( Byeon, K; Chun, KJ; Im, SI; Kim, JS; On, YK; Park, KM; Park, SJ, 2014)
"A prospective, randomized study was conducted to evaluate the efficacy and tolerability of oral propafenone and quinidine for the conversion of paroxysmal atrial fibrillation (AF)."5.14Efficacy and tolerability of oral propafenone versus quinidine in the treatment of recent onset atrial fibrillation: A randomized, prospective study. ( Kochanowski, J; Kosior, DA; Opolski, G; Piatkowski, R; Postuła, M; Rabczenko, D; Scisło, P, 2009)
"This prospective, randomized, single-blinded, placebo-controlled study compared the efficacy and safety of sotalol and propafenone when used for long-term prevention of atrial fibrillation."5.11Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation. ( Chlouverakis, GI; Hamilos, ME; Igoumenidis, NE; Klapsinos, NC; Kochiadakis, GE; Tzerakis, PG; Vardas, PE, 2004)
"The objective of this randomized, double-blind, placebo-controlled clinical trial was to test the efficacy and safety of a new sustained-release preparation of the antiarrhythmic drug propafenone (propafenone SR) in reducing the frequency of symptomatic arrhythmia recurrences in patients with atrial fibrillation (AF)."5.10Efficacy and safety of sustained-release propafenone (propafenone SR) for patients with atrial fibrillation. ( Carlson, M; Fava, G; Page, RL; Pritchett, EL; Undesser, K, 2003)
"We report a double-blind, multicenter, multinational, placebo-controlled, and well-controlled trial to prove that the sustained-release (SR) formulation of propafenone is superior to placebo in preventing symptoms of paroxysmal atrial fibrillation (AF)."5.10Efficacy and safety of propafenone sustained release in the prophylaxis of symptomatic paroxysmal atrial fibrillation (The European Rythmol/Rytmonorm Atrial Fibrillation Trial [ERAFT] Study). ( Camez, A; Eberle, S; Hewkin, A; Kalsch, B; Lip, GY; Lombardi, F; Meinertz, T; Sadowski, ZP, 2002)
"To evaluate, in a prospective and randomized fashion, the efficacy of a pretreatment with verapamil (V) in reducing recurrences of atrial fibrillation (AF) after electrical cardioversion (C)."5.09Pretreatment with verapamil in patients with persistent or chronic atrial fibrillation who underwent electrical cardioversion. ( De Matteis, C; De Simone, A; Di Napoli, T; Di Stasio, M; Gasparini, M; Petrazzuoli, F; Rotunno, R; Stabile, G; Turco, P; Vitale, DF, 1999)
"Amiodarone and propafenone were superior to sotalol in maintaining long-term normal sinus rhythm in patients with atrial fibrillation."5.09Amiodarone, sotalol, or propafenone in atrial fibrillation: which is preferred to maintain normal sinus rhythm? ( Chrysostomakis, SI; Igoumenidis, NE; Kaleboubas, MD; Kochiadakis, GE; Marketou, ME; Mavrakis, HE; Vardas, PE, 2000)
"This study was performed to evaluate, using a randomized double-blind, placebo-controlled protocol, the long-term efficacy and safety of propafenone and sotalol in maintaining sinus rhythm after conversion of recurrent symptomatic atrial fibrillation (AF)."5.09Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation. ( Bellandi, F; Dabizzi, RP; Frascarelli, F; Giovannini, T; Leoncini, M; Maioli, M; Simonetti, I, 2001)
"The study consisted of a 3-month treatment with oral propafenone hydrochloride or quinidine sulphate in patients with paroxysmal symptomatic atrial fibrillation, according to a double-blind randomized system."5.08Comparisons of oral propafenone and quinidine as an initial treatment option in patients with symptomatic paroxysmal atrial fibrillation: a double-blind, randomized trial. ( Chang, MS; Chen, SA; Chiang, CE; Lee, SH; Tai, CT; Wang, SP; Wen, ZC, 1996)
"Propafenone, given before electrical cardioversion for chronic atrial fibrillation does not affect the mean defibrillation threshold or the rate of successful arrhythmia conversion."5.08Effects of oral propafenone administration before electrical cardioversion of chronic atrial fibrillation: a placebo-controlled study. ( Bianconi, L; Castro, A; Chieffi, M; Lukic, V; Mennuni, M; Santini, M, 1996)
"This multicentre, randomized, double-blind study, conducted in parallel groups, was designed to compare the efficacy and safety of cibenzoline (C) and oral propafenone (P) in the prevention of recurrent atrial arrhythmias (M) over a 6-month period."5.08[Cibenzoline versus propafenone by the oral route for preventing recurrence of atrial arrhythmia: multicenter, randomized, double-blind study]. ( Bleinc, D; Canler, A; Lardoux, H; Maison Blanche, P; Marchand, X; Péraudeau, P; Rouesnel, P; Scheck, F, 1996)
"To evaluate the efficacy of propafenone for suppression of recurrent paroxysmal symptomatic atrial fibrillation (AF), patients with frequent episodes of AF entered an open-label, dose-ranging study to determine the maximal tolerated dose of propafenone and were subsequently randomized to alternate between propafenone and placebo every month for 4 months."5.06Usefulness of propafenone for recurrent paroxysmal atrial fibrillation. ( Connolly, SJ; Hoffert, DL, 1989)
"Sixteen patients with ventricular tachycardia (VT) or nonfatal cardiac arrest were treated with propafenone (P), 900 mg/day."5.05Clinical efficacy and electrophysiology of oral propafenone for ventricular tachycardia. ( Connolly, SJ; Echt, DS; Kates, RE; Lebsack, CS; Mason, JW; Winkle, RA, 1983)
"Among the drugs recommended to prevent recurrences of atrial fibrillation after external electric shock, antiarrhythmic agents of classes Ia (quinidine, disopyramide), Ic (cibenzoline, flecainide, propafenone) and III (sotalol) seem to have the same effectiveness in maintaining the sinus rhythm in about 50 percent of the cases after 6 months and one year."4.78[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock]. ( Brechenmacher, C; Chauvin, M; Koenig, A; Theolade, R, 1993)
"The clinical outcomes of 114 patients with atrial fibrillation who had been treated with the innovator propafenone, and in whom the drug was then replaced with generic propafenone because of cost containment, were compared."3.72Efficacy of substituting innovator propafenone for its generic formulation in patients with atrial fibrillation. ( Amit, G; Bonneh, DY; Grosbard, A; Ilia, R; Katz, A; Liss, T; Rosen, A; Wagshal, AB, 2004)
"One hundred and ninety-six patients with stable atrial fibrillation of recent onset received propafenone (98 patients) or Amiodarone (98 patients) intravenously."3.68[The efficacy of intravenous propafenone and amiodarone in the conversion of recent-onset atrial fibrillation. A 1-year follow-up with oral treatment]. ( Bellandi, F; Cantini, F; Dabizzi, RP; Palchetti, R; Pedone, T, 1993)
"To determine the electrophysiological properties of oral propafenone, 50 patients (39 male and 11 female, aged 31 to 80 years) with sustained ventricular tachycardia or ventricular fibrillation underwent serial electrophysiological drug testing, using propafenone (750 to 900 mg daily) as the anti-arrhythmic regimen of first choice."3.68Acute and long-term efficacy of propafenone in patients with sustained ventricular tachyarrhythmias: assessment with programmed ventricular stimulation. ( Frohner, K; Hief, C; Podczeck, A; Steinbach, KK; Stix, G, 1991)
"Propafenone may be effective in some patients for long term prevention of atrial fibrillation, although efficacy may decrease over time."3.68Long term efficacy of propafenone for prevention of atrial fibrillation. ( Kerr, CR; Kyles, AE; Murdock, CJ; Vorderbrugge, S; Yeung-Lai-Wah, JA, 1991)
"One hundred and fourteen patients were included in an open multicenter trial of the prevention of atrial arrhythmias by propafenone and of the tolerability of this anti-arrhythmic agent after a year."3.68[Efficacy and tolerance of propafenone in the prevention after a year of recurrent atrial arrhythmia. Results of a multicenter study of 114 patients]. ( Maarek-Charbit, M; Motté, G; Sirinelli, A, 1992)
"In order to determine the efficacy of type 1C agents (flecainide, encainide, propafenone) in patients with atrial fibrillation who have failed to maintain sinus rhythm with type 1A agents (quinidine, procainamide, disopyramide), 147 patients, that were admitted into the John Dempsey Hospital with new or recurrent atrial fibrillation between 1987-1991, were studied retrospectively."3.68Efficacy of type 1C antiarrhythmic agents for treatment of resistant atrial fibrillation. ( Grey, E; Silverman, DI, 1993)
"One hundred nine patients with recurrent episodes of symptomatic atrial fibrillation or flutter, or both, who had failed one to five previous antiarrhythmic drug trials were treated with propafenone and, subsequently, sotalol if atrial fibrillation recurred."3.68Therapy of refractory symptomatic atrial fibrillation and atrial flutter: a staged care approach with new antiarrhythmic drugs. ( Antman, EM; Beamer, AD; Cantillon, C; Friedman, PL; McGowan, N, 1990)
"The antiarrhythmic effect of oral propafenone was evaluated in 10 patients with Wolff-Parkinson-White syndrome presenting with non-ventricular arrhythmias (paroxysmal supraventricular tachycardia n = 7, atrial fibrillation or flutter n = 3)."3.68Propafenone in the prevention of non-ventricular arrhythmias associated with the Wolff-Parkinson-White syndrome. ( Kallikazaros, I; Papoutsakis, P; Stefanadis, C; Vassiliadis, I, 1990)
"Propafenone was administered to 29 patients who had multiple episodes of recurrent ventricular tachycardia (VT) or ventricular fibrillation (VF) despite previous antiarrhythmic therapy."3.67Propafenone treatment of recurrent ventricular tachycardia: comparison of continuous electrocardiographic recording and electrophysiologic study in predicting drug efficacy. ( Heger, JJ; Hubbard, J; Miles, WM; Prystowsky, EN; Zipes, DP, 1984)
"The purpose of our study was to assess the efficacy of Propafenon in comparison with Disopyramide in the long-term treatment of repetitive ventricular tachycardia."3.67[Comparative study on the efficacy of disopyramide and propafenone in the prevention of the recurrence of ventricular tachycardia]. ( Bomba, E; Bracchetti, D; Capucci, A; Lombardi, G; Naccarella, F; Palmieri, M, 1984)
"Electrophysiologic and hemodynamic studies were performed before and after intravenous infusion of a new antiarrhythmic agent, propafenone, in 28 patients with recurrent ventricular tachycardia."3.67Electrophysiologic and hemodynamic effects of intravenous propafenone in patients with recurrent ventricular tachycardia. ( DiCarlo, L; Morady, F; Scheinman, MM; Schwartz, AB; Shapiro, W; Shen, EN; Sung, RJ, 1984)
"Sixty patients who had recurrent episodes of symptomatic atrial fibrillation or flutter, or both, and who had failed one to five prior drug trials were treated with open label oral propafenone hydrochloride."3.67Long-term oral propafenone therapy for suppression of refractory symptomatic atrial fibrillation and atrial flutter. ( Antman, EM; Beamer, AD; Cantillon, C; Friedman, PL; Goldman, L; McGowan, N, 1988)
"The efficacy of Propafenone to prevent exercise-induced ventricular arrhythmias (EIVA) has been studied in eleven patients affected by ischemic heart disease."3.67[Effects of propafenone on arrhythmias induced by exertion in patients with ischemic cardiopathy]. ( Arrigo, F; Giannetto, M; Luzza, F; Oreto, G; Patané, S; Virga, T, 1987)
" Despite careful precautions, serious proarrhythmias, the major limiting side effect of dofetilide, still occurred during long-term follow-up."2.73Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function. ( Bauman, JL; Kehoe, RF; Leal, S; Mykytsey, A; Razminia, M; Saleem, M; Wang, T; Zheutlin, T, 2007)
"However, patients with no symptomatic recurrences of AF had higher scores at 3 months on measures of global well-being than those with recurrences in the first 3 months (7."2.70Quality of life improves with treatment in the Canadian Trial of Atrial Fibrillation. ( Connolly, SJ; Dorian, P; Green, M; Newman, D; Paquette, M; Roy, D; Talajic, M, 2002)
"The frequent recurrence of paroxysmal atrial fibrillation (PAF) despite the use of standard antiarrhythmic agents prompted the use of new therapeutic approaches."2.69Control of paroxysmal atrial fibrillation recurrence using combined administration of propafenone and quinidine. ( Chow, MS; Fan, C; Lau, CP; Tang, MO; Tse, HF, 2000)
"In case of PAF recurrence pts withdrew from the study."2.68[Comparison of anti-arrhythmic therapy guided by the transesophageal electropharmacologic test and emperic therapy in the prophylaxis of atrial fibrillation recurrence]. ( Burattini, M; Carunchio, A; Ceci, V; Coletta, C; Fera, MS; Galati, A; Mazza, A, 1997)
"The time to first recurrence was prolonged for the overall group of 23 patients while they received propafenone (P = 0."2.67Propafenone treatment of symptomatic paroxysmal supraventricular arrhythmias. A randomized, placebo-controlled, crossover trial in patients tolerating oral therapy. ( McCarthy, EA; Pritchett, EL; Wilkinson, WE, 1991)
"Atrial flutter is most often arising from a macroreentry circuit in the right atrium or around scar tissue in case or previous cardiothoracic surgery."2.43[Atrial flutter and fibrillation]. ( Scharf, C, 2005)
"Recurrence was not affected by the drug used for cardioversion (P = 0."1.40Advanced interatrial block is associated with recurrence of atrial fibrillation post pharmacological cardioversion. ( Baranchuk, A; Chiale, PA; Conde, D; de Luna, AB; Enriquez, A; Hopman, W; Mondragon, I, 2014)
"Propafenone was prescribed at the initial dose of 600 mg/day in 65% of patients."1.31[Efficacy and tolerance of propafenone after correction of atrial fibrillation: PEPS pharmaco-epidemiologic study]. ( Davy, JM; Funck-Brentano, C; Jaillon, P; Mary-Krause, M; Simon, T; Weingrod, M, 2002)
"She also developed severe arrhythmia during her hospital course."1.30Recurrent convulsions and cardiac conduction disturbances after propafenone overdose. ( Buffet, M; Grossenbacher, F; Lamiable, D; Rambourg-Schepens, MO, 1999)
" In this study, we prospectively investigated the effects of AFI ablation and continuation of drug therapy in patients with AF who developed AFI due to long-term administration of class IC antiarrhythmic drugs."1.30Radiofrequency ablation of atrial flutter due to administration of class IC antiarrhythmic drugs for atrial fibrillation. ( Jung, W; Lewalter, T; Lüderitz, B; Schumacher, B; Vahlhaus, C; Wolpert, C, 1999)
"In our patient, recurrences of ventricular fibrillation were not prevented either by lidocaine, or amiodarone."1.29Sixty-six episodes of ventricular fibrillation within four hours: electrical stability restored by propafenone. ( Bellone, P; Spirito, P; Vecchio, C, 1994)
"Three patients experienced recurrence of AF in the early follow-up."1.29Role of transesophageal pacing in recurrent atrial fibrillation. Experience with propafenone. ( Bellizzi, G; Candelmo, F; Foffa, A; Guarino, P; Martino, DF; Morella, A; Parente, A; Turco, P; Viola, V, 1994)
"Propafenone has been efficient in preventing supraventricular tachycardias in all patients."1.29[Propafenone efficacy in preventing supraventricular tachycardia in childhood]. ( Barrenetxea, JI; Bodegas, A; Cabrera, A; Galdeano, JM; Idígoras, G; Pastor, E; Pérez García, P; Rumoroso, JR; Sarrionaindía, MJ; Sota, J, 1994)
" Adverse effects were encountered in 7 patients: in 1 case worsened arrhythmia and in 6 patients, with long-lasting arrhythmias, congestive heart failure."1.28[The emergency treatment of supraventricular tachyarrhythmias: the efficacy and safety of intravenous propafenone]. ( Annoni, P; Baroffio, R; Bossi, M; Cazzaniga, L; Ciaramella, C; Guzzini, F; Maestroni, A; Tisi, G, 1992)
"Evaluation revealed mitral valve prolapse with minimal mitral regurgitation, and normal left ventricular size and function."1.28New onset ventricular tachycardia during pregnancy. ( Braverman, AC; Bromley, BS; Rutherford, JD, 1991)
"Two patients with recurrences of sustained VT in this group were later successfully treated with propafenone, 900 mg/day; overall, 8 of 9 patients with recurrences of sustained VT were successfully treated with 900 mg/day."1.27Propafenone for refractory ventricular arrhythmias: correlation with drug plasma levels during long-term treatment. ( Ambrosioni, E; Bracchetti, D; Marchesini, B; Naccarella, F; Palmieri, M, 1984)

Research

Studies (70)

TimeframeStudies, this research(%)All Research%
pre-199014 (20.00)18.7374
1990's29 (41.43)18.2507
2000's24 (34.29)29.6817
2010's2 (2.86)24.3611
2020's1 (1.43)2.80

Authors

AuthorsStudies
Huang, R1
Lin, J1
Gong, K1
Chen, L1
Fan, L1
Zhang, F1
Zhang, Y1
Chen, X1
Xu, Z1
Enriquez, A1
Conde, D1
Hopman, W1
Mondragon, I1
Chiale, PA1
de Luna, AB1
Baranchuk, A1
Chun, KJ1
Byeon, K1
Im, SI1
Park, KM1
Park, SJ1
Kim, JS1
On, YK1
Stanaitiene, G1
Babarskiene, RM1
Daubert, JP1
Kosior, DA1
Kochanowski, J1
Scisło, P1
Piatkowski, R1
Postuła, M1
Rabczenko, D1
Opolski, G1
Simon, T1
Mary-Krause, M1
Funck-Brentano, C1
Davy, JM1
Weingrod, M1
Jaillon, P1
Meinertz, T1
Lip, GY1
Lombardi, F1
Sadowski, ZP1
Kalsch, B1
Camez, A1
Hewkin, A1
Eberle, S1
Mattioli, AV1
Bonatti, S1
Bonetti, L1
Mattioli, G1
Friberg, J1
Gadsbøll, N1
Pritchett, EL2
Page, RL1
Carlson, M1
Undesser, K1
Fava, G1
Lee, JK2
Klein, GJ3
Krahn, AD2
Yee, R2
Zarnke, K2
Simpson, C2
Skanes, A2
Dorian, P2
Mangat, I1
Amit, G1
Rosen, A1
Wagshal, AB1
Bonneh, DY1
Liss, T1
Grosbard, A1
Ilia, R1
Katz, A1
Bertaglia, E1
Bonso, A1
Zoppo, F1
Proclemer, A1
Verlato, R1
Corò, L1
Mantovan, R1
Themistoclakis, S1
Raviele, A1
Pascotto, P1
Kochiadakis, GE2
Igoumenidis, NE2
Hamilos, ME1
Tzerakis, PG1
Klapsinos, NC1
Chlouverakis, GI1
Vardas, PE2
Scharf, C1
Gorenek, B1
Cavusoglu, Y1
Goktekin, O1
Birdane, A1
Kudaiberdieva, G1
Ata, N1
Unalir, A1
Timuralp, B1
Janko, S1
Hoffmann, E1
Mykytsey, A1
Bauman, JL1
Razminia, M1
Zheutlin, T1
Wang, T1
Saleem, M1
Leal, S1
Kehoe, RF1
Connolly, SJ3
Kates, RE1
Lebsack, CS1
Echt, DS1
Mason, JW1
Winkle, RA1
Palmieri, M2
Capucci, A1
Lombardi, G1
Naccarella, F2
Bomba, E1
Bracchetti, D2
Marchesini, B1
Ambrosioni, E1
Heger, JJ1
Hubbard, J1
Zipes, DP1
Miles, WM1
Prystowsky, EN1
Shen, EN2
Sung, RJ2
Morady, F2
Schwartz, AB1
Scheinman, MM1
DiCarlo, L1
Shapiro, W1
Waleffe, A1
Mary-Rabine, L1
de Rijbel, R1
Soyeur, D1
Legrand, V1
Kulbertus, HE1
Grey, E1
Silverman, DI1
Siebels, J1
Cappato, R1
Rüppel, R1
Schneider, MA1
Kuck, KH1
Reimold, SC2
Lamas, GA1
Cantillon, CO2
Antman, EM4
Alboni, P1
Scarfò, S1
Fucà, G1
Paparella, N1
Pedini, I1
Mele, D1
Turco, P2
Guarino, P1
Parente, A1
Viola, V1
Candelmo, F1
Bellizzi, G1
Foffa, A1
Morella, A1
Martino, DF1
Bodegas, A1
Cabrera, A1
Sarrionaindía, MJ1
Idígoras, G1
Rumoroso, JR1
Pérez García, P1
Pastor, E1
Galdeano, JM1
Sota, J1
Barrenetxea, JI1
Bellone, P1
Spirito, P1
Vecchio, C1
Koenig, A1
Theolade, R1
Chauvin, M1
Brechenmacher, C1
Bellandi, F3
Cantini, F2
Pedone, T1
Dabizzi, RP3
Palchetti, R2
Friedman, PL3
Lee, SH1
Chen, SA1
Chiang, CE1
Tai, CT1
Wen, ZC1
Wang, SP1
Chang, MS1
Bianconi, L1
Mennuni, M1
Lukic, V1
Castro, A1
Chieffi, M1
Santini, M1
Lardoux, H1
Maison Blanche, P1
Marchand, X1
Canler, A1
Rouesnel, P1
Bleinc, D1
Péraudeau, P1
Scheck, F1
Fera, MS1
Carunchio, A1
Burattini, M1
Mazza, A1
Coletta, C1
Galati, A1
Ceci, V1
Mugnaioni, G1
Schumacher, B1
Jung, W1
Lewalter, T1
Vahlhaus, C1
Wolpert, C1
Lüderitz, B1
Nabar, A1
Rodriguez, LM1
Timmermans, C1
Smeets, JL1
Wellens, HJ1
Rambourg-Schepens, MO1
Grossenbacher, F1
Buffet, M1
Lamiable, D1
De Simone, A1
Stabile, G1
Vitale, DF1
Di Stasio, M1
Petrazzuoli, F1
Gasparini, M1
De Matteis, C1
Rotunno, R1
Di Napoli, T1
Ergene, U1
Ergene, O1
Fowler, J1
Kinay, O1
Cete, Y1
Oktay, C1
Nazli, C1
Spindler, B1
Lau, CP1
Chow, MS1
Tse, HF1
Tang, MO1
Fan, C1
Marketou, ME1
Chrysostomakis, SI1
Mavrakis, HE1
Kaleboubas, MD1
Michelucci, A1
Lazzeri, C1
Padeletti, L1
Bagliani, G1
Colella, A1
Sabini, A1
Zipoli, R1
Costoli, A1
Pieragnoli, P1
Gensini, GF1
Franchi, F1
Simonetti, I1
Leoncini, M1
Frascarelli, F1
Giovannini, T1
Maioli, M1
Lin, JL1
Lai, LP1
Tseng, YZ1
Lien, WP1
Huang, SK1
Paquette, M1
Newman, D1
Green, M1
Talajic, M1
Roy, D1
Sirinelli, A1
Maarek-Charbit, M1
Motté, G1
Tisi, G1
Annoni, P1
Baroffio, R1
Cazzaniga, L1
Ciaramella, C1
Guzzini, F1
Maestroni, A1
Bossi, M1
Kumagai, K1
Yamanouchi, Y1
Hiroki, T1
Arakawa, K1
Kyles, AE1
Murdock, CJ1
Yeung-Lai-Wah, JA1
Vorderbrugge, S1
Kerr, CR2
Braverman, AC1
Bromley, BS1
Rutherford, JD1
Podczeck, A1
Frohner, K1
Hief, C1
Stix, G1
Steinbach, KK1
McCarthy, EA1
Wilkinson, WE1
Beamer, AD2
Cantillon, C2
McGowan, N2
Vassiliadis, I1
Papoutsakis, P1
Kallikazaros, I1
Stefanadis, C1
Menozzi, C1
Brignole, M1
Monducci, I1
Lolli, G1
Hoffert, DL1
Musto, B1
D'Onofrio, A1
Cavallaro, C1
Musto, A1
Axelson, JE1
Cooper, JC1
Marchlinski, FE1
Goldman, L1
Patané, S1
Virga, T1
Giannetto, M1
Luzza, F1
Oreto, G1
Arrigo, F1
Keung, E1
Huycke, E1
Dohrmann, ML1
Nguyen, N1

Clinical Trials (6)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Propafenone Versus Dronedarone for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation After DC Cardioversion[NCT01991119]98 participants (Actual)Interventional2011-05-31Completed
First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation - a Randomized Study Comparing Early Trigger Isolation Using the Cryoballoon Versus Antiarrhythmic Medication[NCT05939076]Phase 3220 participants (Anticipated)Interventional2023-08-21Not yet recruiting
Antiarrhythmic Drugs Assessment in Preventing Atrial Fibrillation[NCT02145546]Phase 4600 participants (Anticipated)Interventional2014-05-31Not yet recruiting
Home-based Videoplethysmographic Detection of Atrial Fibrillation[NCT04267133]256 participants (Actual)Interventional2018-05-24Completed
Subclinical Postoperative Atrial Fibrillation[NCT02522364]150 participants (Anticipated)Interventional2015-08-31Recruiting
[NCT00005237]0 participants Observational1988-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Area Under the Receiver Operating Characteristic Curve (AUC) for the Detection of Atrial Fibrillation

The outcome measure is the AUC of the curve obtained from the ROC analysis. The curve is a combination of specificity and sensitivity of detecting atrial fibrillation. The range of the curve is 0.5-1.0 where 0.5 would be random detection of atrial fibrillation and 1.0 would be perfect performance. (NCT04267133)
Timeframe: 2 weeks

Interventionprobability (Number)
All Participants0.74

Reviews

3 reviews available for propafenone and Recrudescence

ArticleYear
[Atrial flutter and fibrillation].
    Praxis, 2005, Nov-09, Volume: 94, Issue:45

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia

2005
[Drug treatment of atrial fibrillation].
    MMW Fortschritte der Medizin, 2006, Apr-13, Volume: 148, Issue:15

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti

2006
[Antiarrhythmic treatment after reduction of atrial fibrillation by external shock].
    Presse medicale (Paris, France : 1983), 1993, Nov-20, Volume: 22, Issue:36

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Disopyramide; El

1993

Trials

30 trials available for propafenone and Recrudescence

ArticleYear
Comparison of Amiodarone and Propafenone in Blanking Period after Radiofrequency Catheter Ablation in Patients with Atrial Fibrillation: A Propensity Score-Matched Study.
    BioMed research international, 2020, Volume: 2020

    Topics: Aged; Amiodarone; Atrial Fibrillation; Catheter Ablation; Female; Humans; Male; Middle Aged; Propafe

2020
Efficacy of dronedarone versus propafenone in the maintenance of sinus rhythm in patients with atrial fibrillation after electrical cardioversion.
    Clinical therapeutics, 2014, Sep-01, Volume: 36, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Dronedaron

2014
Efficacy of dronedarone versus propafenone in the maintenance of sinus rhythm in patients with atrial fibrillation after electrical cardioversion.
    Clinical therapeutics, 2014, Sep-01, Volume: 36, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Dronedaron

2014
Efficacy of dronedarone versus propafenone in the maintenance of sinus rhythm in patients with atrial fibrillation after electrical cardioversion.
    Clinical therapeutics, 2014, Sep-01, Volume: 36, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Dronedaron

2014
Efficacy of dronedarone versus propafenone in the maintenance of sinus rhythm in patients with atrial fibrillation after electrical cardioversion.
    Clinical therapeutics, 2014, Sep-01, Volume: 36, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Dronedaron

2014
[Impact of electrical shock waveform and paddle positions on efficacy of direct current cardioversion for atrial fibrillation].
    Medicina (Kaunas, Lithuania), 2008, Volume: 44, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Body Mass Index; Chi-Square Distribut

2008
Efficacy and tolerability of oral propafenone versus quinidine in the treatment of recent onset atrial fibrillation: A randomized, prospective study.
    Cardiology journal, 2009, Volume: 16, Issue:6

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; B

2009
Efficacy and safety of propafenone sustained release in the prophylaxis of symptomatic paroxysmal atrial fibrillation (The European Rythmol/Rytmonorm Atrial Fibrillation Trial [ERAFT] Study).
    The American journal of cardiology, 2002, Dec-15, Volume: 90, Issue:12

    Topics: Acute Disease; Anti-Arrhythmia Agents; Atrial Fibrillation; Delayed-Action Preparations; Double-Blin

2002
Left atrial size after cardioversion for atrial fibrillation: effect of external direct current shock.
    Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2003, Volume: 16, Issue:3

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function, Left; Blood Flow Velocity

2003
Intracardiac low-energy versus transthoracic high-energy direct-current cardioversion of atrial fibrillation: a randomised comparison.
    Cardiology, 2003, Volume: 99, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biomarkers; Creatine Kinase; Electric

2003
Efficacy and safety of sustained-release propafenone (propafenone SR) for patients with atrial fibrillation.
    The American journal of cardiology, 2003, Oct-15, Volume: 92, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Fibrillation; C

2003
Rate-control versus conversion strategy in postoperative atrial fibrillation: trial design and pilot study results.
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:2

    Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Atrial Fib

2003
Quality of life variables in the selection of rate versus rhythm control in patients with atrial fibrillation: observations from the Canadian Trial of Atrial Fibrillation.
    Cardiac electrophysiology review, 2003, Volume: 7, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Health Status Indicators; Humans; Propafeno

2003
Sotalol versus propafenone for long-term maintenance of normal sinus rhythm in patients with recurrent symptomatic atrial fibrillation.
    The American journal of cardiology, 2004, Dec-15, Volume: 94, Issue:12

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Male; Middle Aged; Propafenone; P

2004
Amiodarone versus Sotalol and Propafenone for prevention of immediate recurrence of atrial fibrillation after internal cardioversion: importance of P wave analysis.
    International journal of cardiology, 2006, Jan-13, Volume: 106, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Female; Humans; Male

2006
Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function.
    Journal of cardiovascular pharmacology and therapeutics, 2007, Volume: 12, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flut

2007
Clinical efficacy and electrophysiology of oral propafenone for ventricular tachycardia.
    The American journal of cardiology, 1983, Dec-01, Volume: 52, Issue:10

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Cardiac Catheterization; Cardiac Pacing, Artificial; C

1983
ICD versus drugs in cardiac arrest survivors: preliminary results of the Cardiac Arrest Study Hamburg.
    Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:3 Pt 2

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Death, Sudden, Cardiac; Defibrillators, Implantable

1993
Risk factors for the development of recurrent atrial fibrillation: role of pacing and clinical variables.
    American heart journal, 1995, Volume: 129, Issue:6

    Topics: Atrial Fibrillation; Cardiac Pacing, Artificial; Chronic Disease; Female; Heart Atria; Heart Disease

1995
Propafenone versus sotalol for suppression of recurrent symptomatic atrial fibrillation.
    The American journal of cardiology, 1993, Mar-01, Volume: 71, Issue:7

    Topics: Aged; Atrial Fibrillation; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Male;

1993
Comparisons of oral propafenone and quinidine as an initial treatment option in patients with symptomatic paroxysmal atrial fibrillation: a double-blind, randomized trial.
    Journal of internal medicine, 1996, Volume: 239, Issue:3

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Electrocardi

1996
Effects of oral propafenone administration before electrical cardioversion of chronic atrial fibrillation: a placebo-controlled study.
    Journal of the American College of Cardiology, 1996, Volume: 28, Issue:3

    Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Chron

1996
[Cibenzoline versus propafenone by the oral route for preventing recurrence of atrial arrhythmia: multicenter, randomized, double-blind study].
    Annales de cardiologie et d'angeiologie, 1996, Volume: 45, Issue:8

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation

1996
[Comparison of anti-arrhythmic therapy guided by the transesophageal electropharmacologic test and emperic therapy in the prophylaxis of atrial fibrillation recurrence].
    Giornale italiano di cardiologia, 1997, Volume: 27, Issue:2

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Echocardiography, Transesophageal; Female; Flecainide;

1997
Pretreatment with verapamil in patients with persistent or chronic atrial fibrillation who underwent electrical cardioversion.
    Journal of the American College of Cardiology, 1999, Volume: 34, Issue:3

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Chronic Disease; Combined Modality Therapy; Elect

1999
Rate-control versus conversion strategy in postoperative atrial fibrillation: a prospective, randomized pilot study.
    American heart journal, 2000, Volume: 140, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Digoxin;

2000
Control of paroxysmal atrial fibrillation recurrence using combined administration of propafenone and quinidine.
    The American journal of cardiology, 2000, Dec-15, Volume: 86, Issue:12

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Arrhythmia Agents; Atrial Fibrillation; Cross-Ov

2000
Amiodarone, sotalol, or propafenone in atrial fibrillation: which is preferred to maintain normal sinus rhythm?
    Pacing and clinical electrophysiology : PACE, 2000, Volume: 23, Issue:11 Pt 2

    Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Heart R

2000
Long-term efficacy and safety of propafenone and sotalol for the maintenance of sinus rhythm after conversion of recurrent symptomatic atrial fibrillation.
    The American journal of cardiology, 2001, Sep-15, Volume: 88, Issue:6

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Surviva

2001
Quality of life improves with treatment in the Canadian Trial of Atrial Fibrillation.
    American heart journal, 2002, Volume: 143, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Canada; Female; Health Status Indicat

2002
Propafenone treatment of symptomatic paroxysmal supraventricular arrhythmias. A randomized, placebo-controlled, crossover trial in patients tolerating oral therapy.
    Annals of internal medicine, 1991, Apr-01, Volume: 114, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Dose-Response Relationship, Drug; Female; Follo

1991
Usefulness of propafenone for recurrent paroxysmal atrial fibrillation.
    The American journal of cardiology, 1989, Apr-01, Volume: 63, Issue:12

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Double-Blind Method; Humans;

1989
Intravenous propafenone for termination of reentrant supraventricular tachycardia. A placebo-controlled, randomized, double-blind, crossover study.
    Annals of internal medicine, 1986, Volume: 105, Issue:5

    Topics: Adult; Aged; Double-Blind Method; Drug Evaluation; Electrocardiography; Humans; Injections, Intraven

1986

Other Studies

37 other studies available for propafenone and Recrudescence

ArticleYear
Advanced interatrial block is associated with recurrence of atrial fibrillation post pharmacological cardioversion.
    Cardiovascular therapeutics, 2014, Volume: 32, Issue:2

    Topics: Aged; Anisoles; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease-Free Survival; Electrocardiogra

2014
Is newer better? Propafenone versus quinidine for conversion of atrial fibrillation.
    Cardiology journal, 2009, Volume: 16, Issue:6

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Drug Therapy, Combinatio

2009
[Efficacy and tolerance of propafenone after correction of atrial fibrillation: PEPS pharmaco-epidemiologic study].
    Archives des maladies du coeur et des vaisseaux, 2002, Volume: 95, Issue:6

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Female; Humans; Male; Middle Aged

2002
Efficacy of substituting innovator propafenone for its generic formulation in patients with atrial fibrillation.
    The American journal of cardiology, 2004, Jun-15, Volume: 93, Issue:12

    Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Drugs, Generic

2004
Different clinical courses and predictors of atrial fibrillation occurrence after transisthmic ablation in patients with preablation lone atrial flutter, coexistent atrial fibrillation, and drug induced atrial flutter.
    Pacing and clinical electrophysiology : PACE, 2004, Volume: 27, Issue:11

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation; Co

2004
[Comparative study on the efficacy of disopyramide and propafenone in the prevention of the recurrence of ventricular tachycardia].
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:5

    Topics: Anti-Arrhythmia Agents; Disopyramide; Drug Evaluation; Heart Ventricles; Humans; Propafenone; Propio

1984
Propafenone for refractory ventricular arrhythmias: correlation with drug plasma levels during long-term treatment.
    The American journal of cardiology, 1984, Nov-01, Volume: 54, Issue:8

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Dizziness; Female; Humans

1984
Propafenone treatment of recurrent ventricular tachycardia: comparison of continuous electrocardiographic recording and electrophysiologic study in predicting drug efficacy.
    The American journal of cardiology, 1984, Nov-14, Volume: 54, Issue:9

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; Electrocardiography; Female; Humans

1984
Electrophysiologic and hemodynamic effects of intravenous propafenone in patients with recurrent ventricular tachycardia.
    Journal of the American College of Cardiology, 1984, Volume: 3, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Electrophysiology; Female; Heart Conduction System;

1984
Electrophysiological effects of propafenone studied with programmed electrical stimulation of the heart in patients with recurrent paroxysmal supraventricular tachycardia.
    European heart journal, 1981, Volume: 2, Issue:4

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Electric Stimulation; Female; Heart; Hear

1981
Efficacy of type 1C antiarrhythmic agents for treatment of resistant atrial fibrillation.
    Pacing and clinical electrophysiology : PACE, 1993, Volume: 16, Issue:12

    Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Disopyramide; Encainide; Female; Flecainide; Hear

1993
Hemodynamic effects of oral propafenone during both sinus rhythm and atrial fibrillation.
    The American journal of cardiology, 1995, Jan-01, Volume: 75, Issue:1

    Topics: Administration, Oral; Atrial Fibrillation; Electrophysiology; Female; Heart Rate; Hemodynamics; Huma

1995
Role of transesophageal pacing in recurrent atrial fibrillation. Experience with propafenone.
    Angiology, 1994, Volume: 45, Issue:2

    Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Cardiac Pacing, Artificial; Echocardiography

1994
[Propafenone efficacy in preventing supraventricular tachycardia in childhood].
    Revista espanola de cardiologia, 1994, Volume: 47, Issue:2

    Topics: Administration, Oral; Adolescent; Child; Child, Preschool; Drug Evaluation; Echocardiography, Dopple

1994
Sixty-six episodes of ventricular fibrillation within four hours: electrical stability restored by propafenone.
    International journal of cardiology, 1994, Mar-01, Volume: 43, Issue:3

    Topics: Amiodarone; Electric Countershock; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; My

1994
[The efficacy of intravenous propafenone and amiodarone in the conversion of recent-onset atrial fibrillation. A 1-year follow-up with oral treatment].
    Giornale italiano di cardiologia, 1993, Volume: 23, Issue:3

    Topics: Administration, Oral; Adult; Aged; Amiodarone; Atrial Fibrillation; Drug Evaluation; Female; Follow-

1993
[Pharmacological cardioversion of isolated atrial fibrillation: recovery of atrial mechanical function and correlation with duration of arrhythmia].
    Giornale italiano di cardiologia, 1997, Volume: 27, Issue:10

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Function; Data Interpretation, Stat

1997
Radiofrequency ablation of atrial flutter due to administration of class IC antiarrhythmic drugs for atrial fibrillation.
    The American journal of cardiology, 1999, Mar-01, Volume: 83, Issue:5

    Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Catheter Ablation

1999
Radiofrequency ablation of "class IC atrial flutter" in patients with resistant atrial fibrillation.
    The American journal of cardiology, 1999, Mar-01, Volume: 83, Issue:5

    Topics: Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Cath

1999
Recurrent convulsions and cardiac conduction disturbances after propafenone overdose.
    Veterinary and human toxicology, 1999, Volume: 41, Issue:3

    Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Heart Conduction System; Humans; Propaf

1999
Must antidysrhythmic agents be given to all patients with new-onset atrial fibrillation?
    The American journal of emergency medicine, 1999, Volume: 17, Issue:7

    Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Monitoring; Emergency

1999
Altered values of heart rate variability in patients with relapse of atrial fibrillation during the first week after electrical cardioversion: preliminary data.
    Italian heart journal : official journal of the Italian Federation of Cardiology, 2001, Volume: 2, Issue:6

    Topics: Aged; Amiodarone; Atrial Fibrillation; Circadian Rhythm; Electric Countershock; Electrocardiography,

2001
Global distribution of atrial ectopic foci triggering recurrence of atrial tachyarrhythmia after electrical cardioversion of long-standing atrial fibrillation: a bi-atrial basket mapping study.
    Journal of the American College of Cardiology, 2001, Mar-01, Volume: 37, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock;

2001
[Efficacy and tolerance of propafenone in the prevention after a year of recurrent atrial arrhythmia. Results of a multicenter study of 114 patients].
    Annales de cardiologie et d'angeiologie, 1992, Volume: 41, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arrhythmias, Cardiac; Blood Pressure; Drug Tolerance; El

1992
[The emergency treatment of supraventricular tachyarrhythmias: the efficacy and safety of intravenous propafenone].
    Cardiologia (Rome, Italy), 1992, Volume: 37, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Chi-Square Distribution; Drug Evaluation; Emergencies; F

1992
Effects of transcatheter cardioversion on chronic lone atrial fibrillation.
    Pacing and clinical electrophysiology : PACE, 1991, Volume: 14, Issue:11 Pt 1

    Topics: Atrial Fibrillation; Cardiac Catheterization; Cardiac Pacing, Artificial; Chronic Disease; Disopyram

1991
Long term efficacy of propafenone for prevention of atrial fibrillation.
    The Canadian journal of cardiology, 1991, Volume: 7, Issue:9

    Topics: Atrial Fibrillation; Female; Follow-Up Studies; Humans; Male; Middle Aged; Propafenone; Recurrence;

1991
New onset ventricular tachycardia during pregnancy.
    International journal of cardiology, 1991, Volume: 33, Issue:3

    Topics: Adult; Electrocardiography; Electrophysiology; Female; Humans; Mitral Valve Insufficiency; Mitral Va

1991
Acute and long-term efficacy of propafenone in patients with sustained ventricular tachyarrhythmias: assessment with programmed ventricular stimulation.
    European heart journal, 1991, Volume: 12, Issue:7

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Coronary Disease; Drug Evaluation; Electric St

1991
Therapy of refractory symptomatic atrial fibrillation and atrial flutter: a staged care approach with new antiarrhythmic drugs.
    Journal of the American College of Cardiology, 1990, Mar-01, Volume: 15, Issue:3

    Topics: Adult; Aged; Atrial Fibrillation; Atrial Flutter; Data Interpretation, Statistical; Drug Administrat

1990
Propafenone in the prevention of non-ventricular arrhythmias associated with the Wolff-Parkinson-White syndrome.
    International journal of cardiology, 1990, Volume: 27, Issue:1

    Topics: Adult; Atrial Fibrillation; Drug Administration Schedule; Echocardiography; Electrocardiography; Ele

1990
Noninvasive serial electrophysiological testing using an implanted pacemaker for management of recurrent ventricular tachycardia.
    Pacing and clinical electrophysiology : PACE, 1986, Volume: 9, Issue:4

    Topics: Aged; Amiodarone; Electrophysiology; Heart Ventricles; Humans; Male; Mexiletine; Pacemaker, Artifici

1986
Electrophysiological effects and clinical efficacy of propafenone in children with recurrent paroxysmal supraventricular tachycardia.
    Circulation, 1988, Volume: 78, Issue:4

    Topics: Cardiac Pacing, Artificial; Child; Electrocardiography; Electrophysiology; Female; Follow-Up Studies

1988
Propafenone for prevention of recurrent atrial fibrillation.
    The American journal of cardiology, 1988, Apr-15, Volume: 61, Issue:11

    Topics: Adult; Aged; Atrial Fibrillation; Female; Follow-Up Studies; Humans; Male; Middle Aged; Propafenone;

1988
Propafenone: new therapy for a tough, old arrhythmia.
    Journal of the American College of Cardiology, 1988, Volume: 12, Issue:4

    Topics: Atrial Fibrillation; Atrial Flutter; Electric Countershock; Humans; Propafenone; Recurrence

1988
Long-term oral propafenone therapy for suppression of refractory symptomatic atrial fibrillation and atrial flutter.
    Journal of the American College of Cardiology, 1988, Volume: 12, Issue:4

    Topics: Actuarial Analysis; Administration, Oral; Atrial Fibrillation; Atrial Flutter; Female; Humans; Male;

1988
[Effects of propafenone on arrhythmias induced by exertion in patients with ischemic cardiopathy].
    Giornale italiano di cardiologia, 1987, Volume: 17, Issue:7

    Topics: Aged; Arrhythmias, Cardiac; Coronary Disease; Electrocardiography; Heart Ventricles; Humans; Male; M

1987