Page last updated: 2024-11-03

propafenone and Pregnancy

propafenone has been researched along with Pregnancy in 10 studies

Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Propafenone is a potent antiarrhythmic agent effective in either supraventricular or ventricular tachyarrhythmias."8.79Propafenone in the treatment of cardiac arrhythmias. A risk-benefit appraisal. ( Boriani, G; Capucci, A, 1995)
"Propafenone is a well-known Class 1C antiarrhythmic agent that has sodium channel blocking properties as well as the ability to block 13 other channels and a modest calcium antagonistic effect."5.72Effect of Rythmol (propafenone HCl) administration during pregnancy in Wistar rats. ( Abd-Allah, ER; Amin, S; Badawy, MA; El Ghareeb, AEW, 2022)
"Propafenone is a potent antiarrhythmic agent effective in either supraventricular or ventricular tachyarrhythmias."4.79Propafenone in the treatment of cardiac arrhythmias. A risk-benefit appraisal. ( Boriani, G; Capucci, A, 1995)
"Evaluation revealed mitral valve prolapse with minimal mitral regurgitation, and normal left ventricular size and function."1.28New onset ventricular tachycardia during pregnancy. ( Braverman, AC; Bromley, BS; Rutherford, JD, 1991)
"In cases of non-immune hydrops fetalis caused by tachyarrhythmias, the transplacental passage of antiarrhythmic drugs may be hampered."1.27Direct intrauterine fetal treatment of fetal tachyarrhythmia with severe hydrops fetalis by antiarrhythmic drugs. ( Bald, R; Gembruch, U; Hansmann, M, 1988)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's3 (30.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's4 (40.00)2.80

Authors

AuthorsStudies
Abd-Allah, ER1
Amin, S1
El Ghareeb, AEW1
Badawy, MA1
Basza, M1
Maciejewski, C1
Bojanowicz, W1
Balsam, P1
Grabowski, M1
Mitkowski, P1
Kempa, M1
Kowalski, O1
Kalarus, Z1
Jaguszewski, M1
Lubiński, A1
Daniłowicz-Szymanowicz, L1
Szumowski, Ł1
Sterliński, M1
Kołtowski, Ł1
Moon, JH1
Kim, YG1
Kim, K1
Osonoi, S1
Wang, S1
Saunders, DC1
Wang, J1
Yang, K1
Kim, H2
Lee, J1
Jeong, JS1
Banerjee, RR1
Kim, SK1
Wu, Y1
Mizukami, H1
Powers, AC1
German, MS1
Bjeloševič, M1
Illíková, V1
Tomko, J1
Olejník, P1
Chalupka, M1
Hatala, R1
Capucci, A1
Boriani, G1
Braverman, AC1
Bromley, BS1
Rutherford, JD1
Libardoni, M1
Piovan, D1
Busato, E1
Padrini, R1
Gembruch, U1
Hansmann, M1
Bald, R1
Brunozzi, LT1
Meniconi, L1
Chiocchi, P1
Liberati, R1
Zuanetti, G1
Latini, R1
Santinelli, V1
de Paola, M1
Turco, P1
Smimmo, D1
Chiariello, M1
Condorelli, M1

Reviews

2 reviews available for propafenone and Pregnancy

ArticleYear
Flecainide in clinical practice.
    Cardiology journal, 2023, Volume: 30, Issue:3

    Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Child; Female; Flecainide; Humans; Pregnancy; Propafeno

2023
Propafenone in the treatment of cardiac arrhythmias. A risk-benefit appraisal.
    Drug safety, 1995, Volume: 12, Issue:1

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Electrophysiology; Female;

1995

Other Studies

8 other studies available for propafenone and Pregnancy

ArticleYear
Effect of Rythmol (propafenone HCl) administration during pregnancy in Wistar rats.
    Journal of biochemical and molecular toxicology, 2022, Volume: 36, Issue:8

    Topics: Animals; Anti-Arrhythmia Agents; Female; Humans; Placenta; Pregnancy; Propafenone; Rats; Rats, Wista

2022
Serotonin Regulates Adult β-Cell Mass by Stimulating Perinatal β-Cell Proliferation.
    Diabetes, 2020, Volume: 69, Issue:2

    Topics: Animals; Animals, Newborn; Cell Proliferation; Female; Glucose; Growth Hormone; Humans; Infant; Insu

2020
Supraventricular tachyarrhythmias during the intrauterine, neonatal, and infant period: A 10-year population-based study.
    Pacing and clinical electrophysiology : PACE, 2020, Volume: 43, Issue:7

    Topics: Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Incidence; Infant; Infant, Newborn; Male; Pregna

2020
New onset ventricular tachycardia during pregnancy.
    International journal of cardiology, 1991, Volume: 33, Issue:3

    Topics: Adult; Electrocardiography; Electrophysiology; Female; Humans; Mitral Valve Insufficiency; Mitral Va

1991
Transfer of propafenone and 5-OH-propafenone to foetal plasma and maternal milk.
    British journal of clinical pharmacology, 1991, Volume: 32, Issue:4

    Topics: Adult; Animals; Female; Fetal Blood; Humans; Maternal-Fetal Exchange; Milk; Pregnancy; Propafenone

1991
Direct intrauterine fetal treatment of fetal tachyarrhythmia with severe hydrops fetalis by antiarrhythmic drugs.
    Fetal therapy, 1988, Volume: 3, Issue:4

    Topics: Anti-Arrhythmia Agents; Female; Fetal Diseases; Flecainide; Humans; Hydrops Fetalis; Medigoxin; Preg

1988
Propafenone in the treatment of chronic ventricular arrhythmias in a pregnant patient.
    British journal of clinical pharmacology, 1988, Volume: 26, Issue:4

    Topics: Adult; Arrhythmias, Cardiac; Female; Humans; Pregnancy; Pregnancy Complications, Cardiovascular; Pro

1988
Wolff-Parkinson-White at risk and propafenone.
    Journal of the American College of Cardiology, 1988, Volume: 11, Issue:5

    Topics: Administration, Oral; Adult; Female; Humans; Pregnancy; Propafenone; Wolff-Parkinson-White Syndrome

1988