propafenone has been researched along with Poisoning in 8 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Propafenone was continuously pumped (velocity=70 mg/kg per h) until the mean blood pressure dropped to 50% of basal level." | 5.56 | Detoxification effects of long-chain versus a mixture of medium- and long-chain triglyceride-based fat emulsion on propafenone poisoning. ( An, X; Mei, Y; Sun, H; Zhang, J, 2020) |
| "Propafenone is an anti-arrhythmic drug used in the management of supraventricular and ventricular arrhythmias." | 5.36 | Propafenone poisoning--a case report with plasma propafenone concentrations. ( Dargan, PI; Jones, AL; Ludman, A; Ovaska, H; Spencer, EP; Wood, DM, 2010) |
| "Propafenone is a class IC antiarrhythmic agent metabolized into two major metabolites, 5-hydroxypropafenone and N-depropylpropafenone." | 5.30 | ECG changes and plasma concentrations of propafenone and its metabolites in a case of severe poisoning. ( Belpaire, F; Buylaert, W; Calle, P; Fonck, K; Haenebalcke, C; Hemeryck, A; Jordaens, L, 1998) |
| " The practical use of the T(M) values as a support to distinguish between different metabolites in the HPLC-DAD analysis of intoxications is demonstrated with cases of poisoning with diphenhydramine, propafenone and methaqualone." | 3.69 | Shift of the high-performance liquid chromatographic retention times of metabolites in relation to the original drug on an RP8 column with acidic mobile phase. ( Herre, S; Pragst, F, 1997) |
| "Propafenone was continuously pumped (velocity=70 mg/kg per h) until the mean blood pressure dropped to 50% of basal level." | 1.56 | Detoxification effects of long-chain versus a mixture of medium- and long-chain triglyceride-based fat emulsion on propafenone poisoning. ( An, X; Mei, Y; Sun, H; Zhang, J, 2020) |
| "Propafenone is an anti-arrhythmic drug used in the management of supraventricular and ventricular arrhythmias." | 1.36 | Propafenone poisoning--a case report with plasma propafenone concentrations. ( Dargan, PI; Jones, AL; Ludman, A; Ovaska, H; Spencer, EP; Wood, DM, 2010) |
| "Maximum occurence of arrhythmias was observed 2." | 1.32 | Acute toxicity of propafenone in a case of suicidal attempt. ( Markovic, P; Petrikova, V; Rajnic, A; Stancak, B, 2004) |
| "Propafenone is a class IC antiarrhythmic agent metabolized into two major metabolites, 5-hydroxypropafenone and N-depropylpropafenone." | 1.30 | ECG changes and plasma concentrations of propafenone and its metabolites in a case of severe poisoning. ( Belpaire, F; Buylaert, W; Calle, P; Fonck, K; Haenebalcke, C; Hemeryck, A; Jordaens, L, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| An, X | 1 |
| Mei, Y | 1 |
| Sun, H | 1 |
| Zhang, J | 1 |
| Ovaska, H | 1 |
| Ludman, A | 1 |
| Spencer, EP | 1 |
| Wood, DM | 1 |
| Jones, AL | 1 |
| Dargan, PI | 1 |
| ten Tusscher, BL | 1 |
| Beishuizen, A | 1 |
| Girbes, AR | 1 |
| Swart, EL | 1 |
| van Leeuwen, RW | 1 |
| Stancak, B | 1 |
| Markovic, P | 1 |
| Rajnic, A | 1 |
| Petrikova, V | 1 |
| Herre, S | 1 |
| Pragst, F | 1 |
| Fonck, K | 1 |
| Haenebalcke, C | 1 |
| Hemeryck, A | 1 |
| Belpaire, F | 1 |
| Jordaens, L | 1 |
| Calle, P | 1 |
| Buylaert, W | 1 |
| Köppel, C | 1 |
| Tenczer, J | 1 |
| Peixoto-Menezes, KM | 1 |
| Lanquetot, H | 1 |
| Furet, Y | 1 |
| Kerourédan, V | 1 |
| Poitrineau, O | 1 |
| Hubiche, M | 1 |
| Autret, E | 1 |
8 other studies available for propafenone and Poisoning
| Article | Year |
|---|---|
Detoxification effects of long-chain versus a mixture of medium- and long-chain triglyceride-based fat emulsion on propafenone poisoning.
Topics: Animals; Disease Models, Animal; Fat Emulsions, Intravenous; Male; Poisoning; Propafenone; Rats; Rat | 2020 |
Propafenone poisoning--a case report with plasma propafenone concentrations.
Topics: Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Coma; Combined Modality Therapy; Drug | 2010 |
Intravenous fat emulsion therapy for intentional propafenone intoxication.
Topics: Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Cardiotonic Agents; Fat Emulsions, Intravenou | 2011 |
Acute toxicity of propafenone in a case of suicidal attempt.
Topics: Acute Disease; Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Humans; Male; Poisoning; Propafe | 2004 |
Shift of the high-performance liquid chromatographic retention times of metabolites in relation to the original drug on an RP8 column with acidic mobile phase.
Topics: Chromatography, High Pressure Liquid; Diphenhydramine; Humans; Methaqualone; Pharmaceutical Preparat | 1997 |
ECG changes and plasma concentrations of propafenone and its metabolites in a case of severe poisoning.
Topics: Anti-Arrhythmia Agents; Chromatography, High Pressure Liquid; Electrocardiography; Female; Half-Life | 1998 |
Formation of formaldehyde adducts from various drugs by use of methanol in a toxicological screening procedure with gas chromatography-mass spectrometry.
Topics: Adrenergic beta-Antagonists; Flecainide; Formaldehyde; Gas Chromatography-Mass Spectrometry; Humans; | 1991 |
[Fatal poisoning caused by the combination propafenone-amitriptyline; apropos of a case].
Topics: Adult; Amitriptyline; Diazepam; Drug Combinations; Electrocardiography; Humans; Male; Poisoning; Pro | 1988 |