propafenone has been researched along with Parasitemia in 1 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Parasitemia: The presence of parasites (especially malarial parasites) in the blood. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previously reported studies identified analogues of propafenone that had potent antimalarial activity, reduced cardiac ion channel activity, and properties that suggested the potential for clinical development for malaria." | 7.78 | Lead optimization of antimalarial propafenone analogues. ( Clark, JA; Connelly, MC; Derisi, JL; Furimsky, A; Gow, J; Guiguemde, WA; Guy, RK; Iyer, LV; Kyle, DE; Lemoff, A; Lowes, D; Mirsalis, J; Parman, T; Pradhan, A; Sigal, M; Tang, L; Wilson, E; Zhu, F, 2012) |
| "Previously reported studies identified analogues of propafenone that had potent antimalarial activity, reduced cardiac ion channel activity, and properties that suggested the potential for clinical development for malaria." | 3.78 | Lead optimization of antimalarial propafenone analogues. ( Clark, JA; Connelly, MC; Derisi, JL; Furimsky, A; Gow, J; Guiguemde, WA; Guy, RK; Iyer, LV; Kyle, DE; Lemoff, A; Lowes, D; Mirsalis, J; Parman, T; Pradhan, A; Sigal, M; Tang, L; Wilson, E; Zhu, F, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lowes, D | 1 |
| Pradhan, A | 1 |
| Iyer, LV | 1 |
| Parman, T | 1 |
| Gow, J | 1 |
| Zhu, F | 1 |
| Furimsky, A | 1 |
| Lemoff, A | 1 |
| Guiguemde, WA | 1 |
| Sigal, M | 1 |
| Clark, JA | 1 |
| Wilson, E | 1 |
| Tang, L | 1 |
| Connelly, MC | 1 |
| Derisi, JL | 1 |
| Kyle, DE | 1 |
| Mirsalis, J | 1 |
| Guy, RK | 1 |
1 other study available for propafenone and Parasitemia
| Article | Year |
|---|---|
Lead optimization of antimalarial propafenone analogues.
Topics: Administration, Oral; Animals; Antimalarials; Chloroquine; Cytochrome P-450 CYP2D6; Cytochrome P-450 | 2012 |