propafenone has been researched along with Injury, Myocardial Reperfusion in 3 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The class Ic steroidal antiarrhythmic agent, Org 7797, was compared with two other Ic agents, flecainide and propafenone for intravenous activity against ischaemia-related cardiac arrhythmias and for electrophysiological actions in vivo." | 7.68 | Effects of Org 7797 on early, late and inducible arrhythmias following coronary artery occlusion in rats and dogs. ( Barron, E; Campbell, JK; Marshall, RJ; Muir, AW; Winslow, E, 1991) |
| "5OHP suppressed reperfusion arrhythmias similar to the parent drug in a concentration-dependent manner." | 5.28 | The relative potency of major metabolites and enantiomers of propafenone in an experimental reperfusion arrhythmia model. ( Follath, F; Ha, HR; Oti-Amoako, K; Vozeh, S, 1990) |
| " The class Ic steroidal antiarrhythmic agent, Org 7797, was compared with two other Ic agents, flecainide and propafenone for intravenous activity against ischaemia-related cardiac arrhythmias and for electrophysiological actions in vivo." | 3.68 | Effects of Org 7797 on early, late and inducible arrhythmias following coronary artery occlusion in rats and dogs. ( Barron, E; Campbell, JK; Marshall, RJ; Muir, AW; Winslow, E, 1991) |
| "5OHP suppressed reperfusion arrhythmias similar to the parent drug in a concentration-dependent manner." | 1.28 | The relative potency of major metabolites and enantiomers of propafenone in an experimental reperfusion arrhythmia model. ( Follath, F; Ha, HR; Oti-Amoako, K; Vozeh, S, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakamura, T | 1 |
| Kashimoto, S | 1 |
| Oguchi, T | 1 |
| Kumazawa, T | 1 |
| Oti-Amoako, K | 1 |
| Vozeh, S | 1 |
| Ha, HR | 1 |
| Follath, F | 1 |
| Winslow, E | 1 |
| Campbell, JK | 1 |
| Barron, E | 1 |
| Marshall, RJ | 1 |
| Muir, AW | 1 |
3 other studies available for propafenone and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Effects of propafenone on function and metabolism in the ischemic working rat heart.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Energy Metabolism; Heart Rate; Hemodynamics; Male; | 1992 |
The relative potency of major metabolites and enantiomers of propafenone in an experimental reperfusion arrhythmia model.
Topics: Animals; Arrhythmias, Cardiac; Biotransformation; Chromatography, High Pressure Liquid; Male; Myocar | 1990 |
Effects of Org 7797 on early, late and inducible arrhythmias following coronary artery occlusion in rats and dogs.
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Electric Stimulation; Estrenes; Female; | 1991 |