propafenone has been researched along with Heart Diseases in 14 studies
Propafenone: An antiarrhythmia agent that is particularly effective in ventricular arrhythmias. It also has weak beta-blocking activity.
propafenone : An aromatic ketone that is 3-(propylamino)propane-1,2-diol in which the hydrogen of the primary hydroxy group is replaced by a 2-(3-phenylpropanoyl)phenyl group. It is a class 1C antiarrhythmic drug with local anesthetic effects, and is used as the hydrochloride salt in the management of supraventricular and ventricular arrhythmias.
Heart Diseases: Pathological conditions involving the HEART including its structural and functional abnormalities.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of oral propafenone in converting recent-onset atrial fibrillation to sinus rhythm has been established by controlled trials." | 9.08 | Oral propafenone to convert recent-onset atrial fibrillation in patients with and without underlying heart disease. A randomized, controlled trial. ( Biffi, M; Boriani, G; Botto, GL; Broffoni, T; Capucci, A; Della Casa, S; Magnani, B; Rubino, I; Sanguinetti, M, 1997) |
| "The effectiveness of oral propafenone in converting recent-onset atrial fibrillation to sinus rhythm has been established by controlled trials." | 5.08 | Oral propafenone to convert recent-onset atrial fibrillation in patients with and without underlying heart disease. A randomized, controlled trial. ( Biffi, M; Boriani, G; Botto, GL; Broffoni, T; Capucci, A; Della Casa, S; Magnani, B; Rubino, I; Sanguinetti, M, 1997) |
| "The effect of long-term treatment with propafenone, metoprolol and amiodarone was studied on the activity of Na,K-adenosine triphosphatase in lymphocytes and the plasma level of cAMP in patients with ventricular arrhythmias." | 3.69 | [The effect of treatment with propafenone, metoprolol and amiodarone on lymphocyte sodium efflux and level of cAMP in serum]. ( Kosmala, W, 1995) |
| "Propafenone is an effective drug for preventing supraventricular tachyarrhythmia, but the incidence of side effects during longterm therapy in patients with such arrhythmias has not been adequately reported." | 2.68 | Safety and tolerability of long-term propafenone therapy for supraventricular tachyarrhythmias. The Propafenone Multicenter Study Group. ( Anderson, JL; Podrid, PJ, 1996) |
| "To evaluate treatment of junctional ectopic tachycardia after cardiac surgery." | 1.31 | [The treatment of postoperative junctional ectopic tachycardia]. ( Cabrera Duro, A; Galdeano Miranda, JM; Macua Biurrun, P; MartÃnez Corrales, P; Pastor Menchaca, E; Pilar Orive, J; Rodrigo Carbonero, D, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.14) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 3 (21.43) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Wybraniec, MT | 1 |
| Kampka, Z | 1 |
| Mizia-Stec, K | 1 |
| Madias, C | 1 |
| Estes, NAM | 1 |
| ten Tusscher, BL | 1 |
| Beishuizen, A | 1 |
| Girbes, AR | 1 |
| Swart, EL | 1 |
| van Leeuwen, RW | 1 |
| Janko, S | 1 |
| Hoffmann, E | 1 |
| Reimold, SC | 1 |
| Lamas, GA | 1 |
| Cantillon, CO | 1 |
| Antman, EM | 1 |
| Kosmala, W | 1 |
| Doni, F | 1 |
| Kheir, A | 1 |
| Manfredi, M | 1 |
| Piemonti, C | 1 |
| Staffiere, E | 1 |
| Todd, S | 1 |
| Rimondini, A | 1 |
| Podrid, PJ | 1 |
| Anderson, JL | 1 |
| Boriani, G | 1 |
| Biffi, M | 1 |
| Capucci, A | 1 |
| Botto, GL | 1 |
| Broffoni, T | 1 |
| Rubino, I | 1 |
| Della Casa, S | 1 |
| Sanguinetti, M | 1 |
| Magnani, B | 1 |
| SoRelle, R | 1 |
| Cabrera Duro, A | 1 |
| Rodrigo Carbonero, D | 1 |
| Galdeano Miranda, JM | 1 |
| MartÃnez Corrales, P | 1 |
| Pastor Menchaca, E | 1 |
| Macua Biurrun, P | 1 |
| Pilar Orive, J | 1 |
| Lombardi, F | 1 |
| Finocchiaro, ML | 1 |
| Dalla Vecchia, L | 1 |
| Rech, R | 1 |
| Castelli, A | 1 |
| Pastine, J | 1 |
| Cappiello, E | 1 |
| Vincenti, A | 1 |
| Landolina, M | 1 |
| Latini, R | 1 |
| Cavalli, A | 1 |
| Gaita, F | 1 |
| Giani, P | 1 |
| Lee, PK | 1 |
| Kerr, CR | 1 |
| Vorderbrugge, S | 1 |
| Qi, AZ | 1 |
| Yeung-Lai-Wah, JA | 1 |
2 reviews available for propafenone and Heart Diseases
| Article | Year |
|---|---|
Pharmacological cardioversion of atrial fibrillation: practical considerations.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Electric Countershock; Heart Diseases; Heart Failure; H | 2023 |
[Drug treatment of atrial fibrillation].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti | 2006 |
5 trials available for propafenone and Heart Diseases
| Article | Year |
|---|---|
Risk factors for the development of recurrent atrial fibrillation: role of pacing and clinical variables.
Topics: Atrial Fibrillation; Cardiac Pacing, Artificial; Chronic Disease; Female; Heart Atria; Heart Disease | 1995 |
[Facilitating effect of propafenone pretreatment in the interruption of atrial flutter by transesophageal pacing].
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Flutter; Cardiac Pacing, Artificial; Esophagus; Female; | 1996 |
Safety and tolerability of long-term propafenone therapy for supraventricular tachyarrhythmias. The Propafenone Multicenter Study Group.
Topics: Administration, Oral; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial | 1996 |
Oral propafenone to convert recent-onset atrial fibrillation in patients with and without underlying heart disease. A randomized, controlled trial.
Topics: Administration, Oral; Anti-Arrhythmia Agents; Atrial Fibrillation; Heart Diseases; Humans; Hypertens | 1997 |
Washout of long-term treatment with flecainide and propafenone in patients with complex ventricular arrhythmias and cardiac disease. Antiarrhythmic Drug Evaluation Group.
Topics: Arrhythmias, Cardiac; Electrocardiography; Flecainide; Heart Diseases; Humans; Male; Middle Aged; Pr | 1992 |
7 other studies available for propafenone and Heart Diseases
| Article | Year |
|---|---|
Class IC antiarrhythmic agents in structural heart disease: Is nothing CAST in stone?
Topics: Anti-Arrhythmia Agents; Heart Diseases; Humans; Propafenone | 2018 |
Intravenous fat emulsion therapy for intentional propafenone intoxication.
Topics: Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Cardiotonic Agents; Fat Emulsions, Intravenou | 2011 |
[The effect of treatment with propafenone, metoprolol and amiodarone on lymphocyte sodium efflux and level of cAMP in serum].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cyclic AMP; Female; Heart Dis | 1995 |
Late-breaking clinical trials at the American Heart Association's scientific sessions 2001.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Clinical Trials as Topic; Coronary Artery Bypass; Coron | 2001 |
[The treatment of postoperative junctional ectopic tachycardia].
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiac Surgical Procedures; Combined Modality Therapy; Female; | 2002 |
Effects of mexiletine, propafenone and flecainide on signal-averaged electrocardiogram.
Topics: Adult; Aged; Aged, 80 and over; Electrocardiography, Ambulatory; Female; Flecainide; Heart Diseases; | 1992 |
Symptomatic sinus node dysfunction associated with the use of propafenone.
Topics: Bradycardia; Cardiac Pacing, Artificial; Heart Diseases; Humans; Propafenone; Sinoatrial Node; Synco | 1988 |